ATE302282T1 - Erhöhte herstellung von sekretierten proteinen durch rekombinante hefezellen - Google Patents
Erhöhte herstellung von sekretierten proteinen durch rekombinante hefezellenInfo
- Publication number
- ATE302282T1 ATE302282T1 AT98933668T AT98933668T ATE302282T1 AT E302282 T1 ATE302282 T1 AT E302282T1 AT 98933668 T AT98933668 T AT 98933668T AT 98933668 T AT98933668 T AT 98933668T AT E302282 T1 ATE302282 T1 AT E302282T1
- Authority
- AT
- Austria
- Prior art keywords
- yeast cells
- recombinant yeast
- increased production
- secreted proteins
- seb1
- Prior art date
Links
- 108090000623 proteins and genes Proteins 0.000 title abstract 3
- 210000005253 yeast cell Anatomy 0.000 title abstract 3
- 102000004169 proteins and genes Human genes 0.000 title abstract 2
- 101100275159 Arabidopsis thaliana COBL7 gene Proteins 0.000 abstract 2
- 101100180341 Arabidopsis thaliana IWS1 gene Proteins 0.000 abstract 2
- 101150005224 SBH1 gene Proteins 0.000 abstract 2
- 101100256357 Schizosaccharomyces pombe (strain 972 / ATCC 24843) seb1 gene Proteins 0.000 abstract 2
- 210000004027 cell Anatomy 0.000 abstract 2
- 101100351303 Caenorhabditis elegans pdfr-1 gene Proteins 0.000 abstract 1
- 102000004190 Enzymes Human genes 0.000 abstract 1
- 108090000790 Enzymes Proteins 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 230000003301 hydrolyzing effect Effects 0.000 abstract 1
- 229920002521 macromolecule Polymers 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/80—Vectors or expression systems specially adapted for eukaryotic hosts for fungi
- C12N15/81—Vectors or expression systems specially adapted for eukaryotic hosts for fungi for yeasts
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/37—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from fungi
- C07K14/39—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from fungi from yeasts
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Chemical & Material Sciences (AREA)
- Mycology (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- General Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- General Health & Medical Sciences (AREA)
- Biophysics (AREA)
- Microbiology (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Biotechnology (AREA)
- Biochemistry (AREA)
- Plant Pathology (AREA)
- Physics & Mathematics (AREA)
- Gastroenterology & Hepatology (AREA)
- Medicinal Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
- Seeds, Soups, And Other Foods (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FI972909A FI972909A0 (fi) | 1997-07-09 | 1997-07-09 | Oekad produktion av avsoendrade proteiner genom rekombinatjaestceller |
| PCT/FI1998/000576 WO1999002716A1 (en) | 1997-07-09 | 1998-07-08 | Increased production of secreted proteins by recombinant yeast cells |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE302282T1 true ATE302282T1 (de) | 2005-09-15 |
Family
ID=8549223
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT98933668T ATE302282T1 (de) | 1997-07-09 | 1998-07-08 | Erhöhte herstellung von sekretierten proteinen durch rekombinante hefezellen |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US6344341B1 (de) |
| EP (1) | EP0994955B1 (de) |
| JP (1) | JP2001509392A (de) |
| AT (1) | ATE302282T1 (de) |
| AU (1) | AU734541B2 (de) |
| CA (1) | CA2296084A1 (de) |
| DE (1) | DE69831242T2 (de) |
| DK (1) | DK0994955T3 (de) |
| ES (1) | ES2247704T3 (de) |
| FI (1) | FI972909A0 (de) |
| WO (1) | WO1999002716A1 (de) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2568788A1 (en) * | 2004-06-16 | 2005-12-29 | Dsm Ip Assets B.V. | Production of polypeptides by improved secretion |
| EP2511372A1 (de) | 2006-11-02 | 2012-10-17 | DSM IP Assets B.V. | Verbesserte Herstellung von sekretierten Proteinen durch filamentöse Pilze |
| AR086200A1 (es) * | 2011-04-22 | 2013-11-27 | Danisco Us Inc | Hongos filamentosos que tienen un fenotipo de viscosidad alterado |
| SG11201608080RA (en) * | 2014-04-17 | 2016-10-28 | Boehringer Ingelheim Rcv Gmbh | Recombinant host cell for expressing proteins of interest |
| CA2948369C (en) | 2014-04-17 | 2023-09-26 | Boehringer Ingelheim Rcv Gmbh & Co Kg | Recombinant host cell engineered to overexpress helper proteins |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3888561T2 (de) | 1987-03-23 | 1994-09-01 | Zymogenetics Inc | Hohe Proteinsyntheserate in Hefe. |
-
1997
- 1997-07-09 FI FI972909A patent/FI972909A0/fi not_active Application Discontinuation
-
1998
- 1998-07-08 AT AT98933668T patent/ATE302282T1/de not_active IP Right Cessation
- 1998-07-08 JP JP2000502210A patent/JP2001509392A/ja active Pending
- 1998-07-08 DK DK98933668T patent/DK0994955T3/da active
- 1998-07-08 DE DE69831242T patent/DE69831242T2/de not_active Expired - Lifetime
- 1998-07-08 WO PCT/FI1998/000576 patent/WO1999002716A1/en not_active Ceased
- 1998-07-08 US US09/446,920 patent/US6344341B1/en not_active Expired - Lifetime
- 1998-07-08 CA CA002296084A patent/CA2296084A1/en not_active Abandoned
- 1998-07-08 AU AU83410/98A patent/AU734541B2/en not_active Ceased
- 1998-07-08 ES ES98933668T patent/ES2247704T3/es not_active Expired - Lifetime
- 1998-07-08 EP EP98933668A patent/EP0994955B1/de not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| DE69831242T2 (de) | 2006-06-29 |
| AU8341098A (en) | 1999-02-08 |
| EP0994955B1 (de) | 2005-08-17 |
| ES2247704T3 (es) | 2006-03-01 |
| AU734541B2 (en) | 2001-06-14 |
| CA2296084A1 (en) | 1999-01-21 |
| DE69831242D1 (de) | 2005-09-22 |
| WO1999002716A1 (en) | 1999-01-21 |
| FI972909A0 (fi) | 1997-07-09 |
| US6344341B1 (en) | 2002-02-05 |
| JP2001509392A (ja) | 2001-07-24 |
| DK0994955T3 (da) | 2005-11-28 |
| EP0994955A1 (de) | 2000-04-26 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification |
Ref document number: 0994955 Country of ref document: EP |
|
| REN | Ceased due to non-payment of the annual fee |