ATE303132T1 - Ophthalmische zubereitung mit n-acetylcystein zur behandlung trockener augen - Google Patents

Ophthalmische zubereitung mit n-acetylcystein zur behandlung trockener augen

Info

Publication number
ATE303132T1
ATE303132T1 AT02765328T AT02765328T ATE303132T1 AT E303132 T1 ATE303132 T1 AT E303132T1 AT 02765328 T AT02765328 T AT 02765328T AT 02765328 T AT02765328 T AT 02765328T AT E303132 T1 ATE303132 T1 AT E303132T1
Authority
AT
Austria
Prior art keywords
cysteine
acetyl
acetylcystein
treatment
dry eyes
Prior art date
Application number
AT02765328T
Other languages
English (en)
Inventor
Enrico Boldrini
Marco Fabrizio Saettone
Patrizia Chetoni
Susi Burgalassi
Boris Giannaccini
Original Assignee
Farmigea Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Farmigea Spa filed Critical Farmigea Spa
Application granted granted Critical
Publication of ATE303132T1 publication Critical patent/ATE303132T1/de

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • A61K31/195Carboxylic acids, e.g. valproic acid having an amino group
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0048Eye, e.g. artificial tears
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • A61P27/04Artificial tears; Irrigation solutions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Ophthalmology & Optometry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
AT02765328T 2001-07-23 2002-07-22 Ophthalmische zubereitung mit n-acetylcystein zur behandlung trockener augen ATE303132T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IT2001RM000438A ITRM20010438A1 (it) 2001-07-23 2001-07-23 Preparato oftalmico a base di n-acetilcisteina per il trattamento della sindrome dell'occhio secco.
PCT/IT2002/000481 WO2003011249A2 (en) 2001-07-23 2002-07-22 Ophthalmic composition containing n-acetylcysteine for the treat ment of dry-eye syndrome

Publications (1)

Publication Number Publication Date
ATE303132T1 true ATE303132T1 (de) 2005-09-15

Family

ID=11455677

Family Applications (1)

Application Number Title Priority Date Filing Date
AT02765328T ATE303132T1 (de) 2001-07-23 2002-07-22 Ophthalmische zubereitung mit n-acetylcystein zur behandlung trockener augen

Country Status (12)

Country Link
US (1) US7321000B2 (de)
EP (1) EP1408929B1 (de)
KR (1) KR20040014657A (de)
CN (1) CN100362989C (de)
AT (1) ATE303132T1 (de)
AU (1) AU2002329042A1 (de)
CA (1) CA2454918A1 (de)
DE (1) DE60205913T2 (de)
ES (1) ES2247372T3 (de)
IT (1) ITRM20010438A1 (de)
MX (1) MXPA03011613A (de)
WO (1) WO2003011249A2 (de)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2011202871B2 (en) * 2005-08-24 2014-06-12 Cumberland Pharmaceuticals Inc. Acetylcysteine composition and uses therefor
US8148356B2 (en) 2005-08-24 2012-04-03 Cumberland Pharmaceuticals, Inc. Acetylcysteine composition and uses therefor
CN100464745C (zh) * 2006-04-07 2009-03-04 山东轩竹医药科技有限公司 乙酰半胱氨酸或其药用盐和细辛脑的药物组合物
KR100855097B1 (ko) * 2006-12-18 2008-08-29 이정상 아세틸시스테인 함유 항-헬리코박터 파이로리 조성물
EP2596112A4 (de) * 2010-07-21 2015-01-21 Cumberland Pharmaceuticals Inc Acetycystein-zusammensetzungen und verwendungsverfahren dafür
DE102013006596A1 (de) * 2013-04-17 2014-10-23 Jaime Guardiola Verfahren zum Herstellen einer sterilen intraokularen Spül-Lösung und Spül-Lösung
EP3139903B1 (de) * 2014-05-07 2019-07-03 Croma-Pharma Gesellschaft m.b.H. Wässrige opthalmische lösung und verfahren zur behandlung von trockenem augensyndrom
TR201819920T4 (tr) 2014-12-12 2019-01-21 Alfa Intes Ind Terapeutica Splendore S R L Kuru göz sendromunun tedavisinde kullanım için oftalmik bileşimler.
US10004761B2 (en) 2016-06-21 2018-06-26 Mark M. Levy Malodor neutralizing composition
WO2018089797A1 (en) * 2016-11-14 2018-05-17 Mingwu Wang Formulations for the treatment of ocular surface diseases and related methods
US20220409526A1 (en) * 2019-11-08 2022-12-29 Retina Foundation Of The Southwest Compounds and implants for treating ocular disorders
KR102283681B1 (ko) * 2020-01-17 2021-07-29 조선대학교 산학협력단 렌즈 형상의 약물 전달 시스템 및 이의 제조 방법
US20250222033A1 (en) * 2024-01-10 2025-07-10 PReye, LLC Therapeutic composition for the treatment of dry eye disease and promotion of ocular health

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1151755B (it) 1982-05-12 1986-12-24 Bruschettini Srl Composizione farmaceutica a carattere di collirio,e procedimento per la sua preparazione
US5256420A (en) * 1991-12-23 1993-10-26 Ciba-Geigy Corporation Method of imparting antimicrobial acitivity to an ophthalmic composition
IT1258781B (it) 1992-01-16 1996-02-29 Zambon Spa Composizione farmaceutica oftalmica contenente n-acetilcisteina e polivinilalcol

Also Published As

Publication number Publication date
US7321000B2 (en) 2008-01-22
EP1408929B1 (de) 2005-08-31
MXPA03011613A (es) 2004-07-01
EP1408929A2 (de) 2004-04-21
WO2003011249A3 (en) 2003-09-25
DE60205913D1 (de) 2005-10-06
ITRM20010438A1 (it) 2003-01-23
CN100362989C (zh) 2008-01-23
ES2247372T3 (es) 2006-03-01
ITRM20010438A0 (it) 2001-07-23
CN1535138A (zh) 2004-10-06
AU2002329042A1 (en) 2003-02-17
WO2003011249A2 (en) 2003-02-13
KR20040014657A (ko) 2004-02-14
CA2454918A1 (en) 2003-02-13
DE60205913T2 (de) 2006-06-29
US20040248847A1 (en) 2004-12-09

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