ATE303132T1 - Ophthalmische zubereitung mit n-acetylcystein zur behandlung trockener augen - Google Patents
Ophthalmische zubereitung mit n-acetylcystein zur behandlung trockener augenInfo
- Publication number
- ATE303132T1 ATE303132T1 AT02765328T AT02765328T ATE303132T1 AT E303132 T1 ATE303132 T1 AT E303132T1 AT 02765328 T AT02765328 T AT 02765328T AT 02765328 T AT02765328 T AT 02765328T AT E303132 T1 ATE303132 T1 AT E303132T1
- Authority
- AT
- Austria
- Prior art keywords
- cysteine
- acetyl
- acetylcystein
- treatment
- dry eyes
- Prior art date
Links
- PWKSKIMOESPYIA-BYPYZUCNSA-N L-N-acetyl-Cysteine Chemical compound CC(=O)N[C@@H](CS)C(O)=O PWKSKIMOESPYIA-BYPYZUCNSA-N 0.000 title abstract 5
- 229960004308 acetylcysteine Drugs 0.000 abstract 4
- 239000000203 mixture Substances 0.000 abstract 2
- 239000004480 active ingredient Substances 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 230000000254 damaging effect Effects 0.000 abstract 1
- 239000003889 eye drop Substances 0.000 abstract 1
- 229940012356 eye drops Drugs 0.000 abstract 1
- 238000009472 formulation Methods 0.000 abstract 1
- 230000000622 irritating effect Effects 0.000 abstract 1
- 230000003472 neutralizing effect Effects 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0048—Eye, e.g. artificial tears
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/04—Artificial tears; Irrigation solutions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
Landscapes
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Ophthalmology & Optometry (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT2001RM000438A ITRM20010438A1 (it) | 2001-07-23 | 2001-07-23 | Preparato oftalmico a base di n-acetilcisteina per il trattamento della sindrome dell'occhio secco. |
| PCT/IT2002/000481 WO2003011249A2 (en) | 2001-07-23 | 2002-07-22 | Ophthalmic composition containing n-acetylcysteine for the treat ment of dry-eye syndrome |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE303132T1 true ATE303132T1 (de) | 2005-09-15 |
Family
ID=11455677
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT02765328T ATE303132T1 (de) | 2001-07-23 | 2002-07-22 | Ophthalmische zubereitung mit n-acetylcystein zur behandlung trockener augen |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US7321000B2 (de) |
| EP (1) | EP1408929B1 (de) |
| KR (1) | KR20040014657A (de) |
| CN (1) | CN100362989C (de) |
| AT (1) | ATE303132T1 (de) |
| AU (1) | AU2002329042A1 (de) |
| CA (1) | CA2454918A1 (de) |
| DE (1) | DE60205913T2 (de) |
| ES (1) | ES2247372T3 (de) |
| IT (1) | ITRM20010438A1 (de) |
| MX (1) | MXPA03011613A (de) |
| WO (1) | WO2003011249A2 (de) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2011202871B2 (en) * | 2005-08-24 | 2014-06-12 | Cumberland Pharmaceuticals Inc. | Acetylcysteine composition and uses therefor |
| US8148356B2 (en) | 2005-08-24 | 2012-04-03 | Cumberland Pharmaceuticals, Inc. | Acetylcysteine composition and uses therefor |
| CN100464745C (zh) * | 2006-04-07 | 2009-03-04 | 山东轩竹医药科技有限公司 | 乙酰半胱氨酸或其药用盐和细辛脑的药物组合物 |
| KR100855097B1 (ko) * | 2006-12-18 | 2008-08-29 | 이정상 | 아세틸시스테인 함유 항-헬리코박터 파이로리 조성물 |
| EP2596112A4 (de) * | 2010-07-21 | 2015-01-21 | Cumberland Pharmaceuticals Inc | Acetycystein-zusammensetzungen und verwendungsverfahren dafür |
| DE102013006596A1 (de) * | 2013-04-17 | 2014-10-23 | Jaime Guardiola | Verfahren zum Herstellen einer sterilen intraokularen Spül-Lösung und Spül-Lösung |
| EP3139903B1 (de) * | 2014-05-07 | 2019-07-03 | Croma-Pharma Gesellschaft m.b.H. | Wässrige opthalmische lösung und verfahren zur behandlung von trockenem augensyndrom |
| TR201819920T4 (tr) | 2014-12-12 | 2019-01-21 | Alfa Intes Ind Terapeutica Splendore S R L | Kuru göz sendromunun tedavisinde kullanım için oftalmik bileşimler. |
| US10004761B2 (en) | 2016-06-21 | 2018-06-26 | Mark M. Levy | Malodor neutralizing composition |
| WO2018089797A1 (en) * | 2016-11-14 | 2018-05-17 | Mingwu Wang | Formulations for the treatment of ocular surface diseases and related methods |
| US20220409526A1 (en) * | 2019-11-08 | 2022-12-29 | Retina Foundation Of The Southwest | Compounds and implants for treating ocular disorders |
| KR102283681B1 (ko) * | 2020-01-17 | 2021-07-29 | 조선대학교 산학협력단 | 렌즈 형상의 약물 전달 시스템 및 이의 제조 방법 |
| US20250222033A1 (en) * | 2024-01-10 | 2025-07-10 | PReye, LLC | Therapeutic composition for the treatment of dry eye disease and promotion of ocular health |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IT1151755B (it) | 1982-05-12 | 1986-12-24 | Bruschettini Srl | Composizione farmaceutica a carattere di collirio,e procedimento per la sua preparazione |
| US5256420A (en) * | 1991-12-23 | 1993-10-26 | Ciba-Geigy Corporation | Method of imparting antimicrobial acitivity to an ophthalmic composition |
| IT1258781B (it) | 1992-01-16 | 1996-02-29 | Zambon Spa | Composizione farmaceutica oftalmica contenente n-acetilcisteina e polivinilalcol |
-
2001
- 2001-07-23 IT IT2001RM000438A patent/ITRM20010438A1/it unknown
-
2002
- 2002-07-22 ES ES02765328T patent/ES2247372T3/es not_active Expired - Lifetime
- 2002-07-22 DE DE60205913T patent/DE60205913T2/de not_active Expired - Fee Related
- 2002-07-22 CN CNB028149521A patent/CN100362989C/zh not_active Expired - Fee Related
- 2002-07-22 MX MXPA03011613A patent/MXPA03011613A/es active IP Right Grant
- 2002-07-22 WO PCT/IT2002/000481 patent/WO2003011249A2/en not_active Ceased
- 2002-07-22 EP EP02765328A patent/EP1408929B1/de not_active Expired - Lifetime
- 2002-07-22 KR KR10-2004-7000142A patent/KR20040014657A/ko not_active Ceased
- 2002-07-22 AU AU2002329042A patent/AU2002329042A1/en not_active Abandoned
- 2002-07-22 CA CA002454918A patent/CA2454918A1/en not_active Abandoned
- 2002-07-22 US US10/484,241 patent/US7321000B2/en not_active Expired - Fee Related
- 2002-07-22 AT AT02765328T patent/ATE303132T1/de not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| US7321000B2 (en) | 2008-01-22 |
| EP1408929B1 (de) | 2005-08-31 |
| MXPA03011613A (es) | 2004-07-01 |
| EP1408929A2 (de) | 2004-04-21 |
| WO2003011249A3 (en) | 2003-09-25 |
| DE60205913D1 (de) | 2005-10-06 |
| ITRM20010438A1 (it) | 2003-01-23 |
| CN100362989C (zh) | 2008-01-23 |
| ES2247372T3 (es) | 2006-03-01 |
| ITRM20010438A0 (it) | 2001-07-23 |
| CN1535138A (zh) | 2004-10-06 |
| AU2002329042A1 (en) | 2003-02-17 |
| WO2003011249A2 (en) | 2003-02-13 |
| KR20040014657A (ko) | 2004-02-14 |
| CA2454918A1 (en) | 2003-02-13 |
| DE60205913T2 (de) | 2006-06-29 |
| US20040248847A1 (en) | 2004-12-09 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification |
Ref document number: 1408929 Country of ref document: EP |
|
| REN | Ceased due to non-payment of the annual fee |