ATE304006T1 - Aminopiperidinderivate als antibakterielles arzneimittel - Google Patents

Aminopiperidinderivate als antibakterielles arzneimittel

Info

Publication number
ATE304006T1
ATE304006T1 AT00945938T AT00945938T ATE304006T1 AT E304006 T1 ATE304006 T1 AT E304006T1 AT 00945938 T AT00945938 T AT 00945938T AT 00945938 T AT00945938 T AT 00945938T AT E304006 T1 ATE304006 T1 AT E304006T1
Authority
AT
Austria
Prior art keywords
antibacterial drug
aminopiperidine derivatives
derivatives
aminopiperidine
antibacterial
Prior art date
Application number
AT00945938T
Other languages
English (en)
Inventor
David Davies
Andrew Lightfoot
Roger Edward Markwell
Neil David Pearson
Original Assignee
Smithkline Beecham Plc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Smithkline Beecham Plc filed Critical Smithkline Beecham Plc
Application granted granted Critical
Publication of ATE304006T1 publication Critical patent/ATE304006T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Plural Heterocyclic Compounds (AREA)
AT00945938T 1999-07-23 2000-07-17 Aminopiperidinderivate als antibakterielles arzneimittel ATE304006T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB9917408.8A GB9917408D0 (en) 1999-07-23 1999-07-23 Compounds
PCT/EP2000/006938 WO2001007432A2 (en) 1999-07-23 2000-07-17 Aminopiperidine derivatives as antibacterials

Publications (1)

Publication Number Publication Date
ATE304006T1 true ATE304006T1 (de) 2005-09-15

Family

ID=10857877

Family Applications (1)

Application Number Title Priority Date Filing Date
AT00945938T ATE304006T1 (de) 1999-07-23 2000-07-17 Aminopiperidinderivate als antibakterielles arzneimittel

Country Status (9)

Country Link
US (2) US7001913B1 (de)
EP (1) EP1214314B1 (de)
JP (1) JP2003505455A (de)
AT (1) ATE304006T1 (de)
AU (1) AU5986200A (de)
DE (1) DE60022523T2 (de)
ES (1) ES2246244T3 (de)
GB (1) GB9917408D0 (de)
WO (1) WO2001007432A2 (de)

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EP1305308B1 (de) 2000-07-26 2006-12-20 Smithkline Beecham Plc Aminopiperidin chinoline und ihre azaisosteren analoga mit antibakterieller wirkung
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GB0031088D0 (en) * 2000-12-20 2001-01-31 Smithkline Beecham Plc Medicaments
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GB0112834D0 (en) 2001-05-25 2001-07-18 Smithkline Beecham Plc Medicaments
GB0118238D0 (en) * 2001-07-26 2001-09-19 Smithkline Beecham Plc Medicaments
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EP1551829B1 (de) * 2002-10-10 2010-04-07 Morphochem Aktiengesellschaft Für Kombinatorische Chemie Neue verbindungen mit antibakterieller aktivität
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WO2006002047A2 (en) 2004-06-15 2006-01-05 Glaxo Group Limited Antibacterial agents
JP2008505920A (ja) * 2004-07-08 2008-02-28 グラクソ　グループ　リミテッド 抗菌剤
EP1845995A4 (de) 2005-01-25 2010-03-03 Glaxo Group Ltd Antibakterielle wirkstoffe
WO2006081182A2 (en) 2005-01-25 2006-08-03 Glaxo Group Limited Antibacterial agents
JP2008528598A (ja) 2005-01-25 2008-07-31 グラクソ グループ リミテッド 抗菌剤
US7511035B2 (en) 2005-01-25 2009-03-31 Glaxo Group Limited Antibacterial agents
JP2008528586A (ja) 2005-01-25 2008-07-31 グラクソ グループ リミテッド 抗菌剤
MY150958A (en) 2005-06-16 2014-03-31 Astrazeneca Ab Compounds for the treatment of multi-drug resistant bacterial infections
JO2952B1 (en) * 2005-08-03 2016-03-15 جانسين فارماسوتيكا ان. في Quinoline derivatives acting as antibacterial agents
ATE536351T1 (de) 2006-01-26 2011-12-15 Actelion Pharmaceuticals Ltd Tetrahydropyran-antibiotika
WO2007118130A2 (en) 2006-04-06 2007-10-18 Glaxo Group Limited Antibacterial agents
KR100760148B1 (ko) 2006-07-19 2007-09-18 주식회사 엘지생활건강 알파-리포산을 안정화시킨 화장료 조성물
EP1921070A1 (de) 2006-11-10 2008-05-14 Boehringer Ingelheim Pharma GmbH & Co. KG Bicyclische Heterocyclen, diese Verbindungen enthaltende Arzneimittel, deren Verwendung und Verfahren zu ihrer Herstelllung
AU2008212999A1 (en) 2007-02-06 2008-08-14 Boehringer Ingelheim International Gmbh Bicyclic heterocycles, drugs containing said compounds, use thereof, and method for production thereof
GB0707706D0 (en) * 2007-04-20 2007-05-30 Glaxo Group Ltd Compounds
EP2005995A1 (de) * 2007-06-22 2008-12-24 Glaxo Group Limited Heterocyclische Verbindungen für die Behandlung von Tuberkulose
US8497369B2 (en) 2008-02-07 2013-07-30 Boehringer Ingelheim International Gmbh Spirocyclic heterocycles medicaments containing said compounds, use thereof and method for their production
TW200944529A (en) 2008-04-15 2009-11-01 Actelion Pharmaceuticals Ltd Tricyclic antibiotics
JP5739802B2 (ja) 2008-05-13 2015-06-24 アストラゼネカ アクチボラグ ４−（３−クロロ−２−フルオロアニリノ）−７−メトキシ−６−｛［１−（ｎ−メチルカルバモイルメチル）ピペリジン−４−イル］オキシ｝キナゾリンのフマル酸塩
EP2313397B1 (de) 2008-08-08 2016-04-20 Boehringer Ingelheim International GmbH Cyclohexyloxy-substituierte heterocyclen, diese verbindungen enthaltende arzneimittel, deren verwendung und verfahren zu ihrer herstellung
EP2332939A1 (de) 2009-11-26 2011-06-15 Æterna Zentaris GmbH Neuartige Naphthyridinderivate und ihre Verwendung als Kinasehemmer
WO2020169593A1 (en) 2019-02-19 2020-08-27 Univerza V Ljubljani Antibacterials based on monocyclic fragments coupled to aminopiperidine naphthyridine scaffold

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Also Published As

Publication number Publication date
US7001913B1 (en) 2006-02-21
DE60022523D1 (de) 2005-10-13
AU5986200A (en) 2001-02-13
EP1214314A2 (de) 2002-06-19
DE60022523T2 (de) 2006-06-29
GB9917408D0 (en) 1999-09-22
US20060079546A1 (en) 2006-04-13
JP2003505455A (ja) 2003-02-12
EP1214314B1 (de) 2005-09-07
WO2001007432A2 (en) 2001-02-01
ES2246244T3 (es) 2006-02-16
WO2001007432A3 (en) 2001-05-25
WO2001007432A8 (en) 2001-09-07

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Legal Events

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RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties