ATE305942T1 - Dextranderivate, verfahren zu deren herstellung und verwendungen als arzneimittel mit spezifischer, biologischer wirkung - Google Patents

Dextranderivate, verfahren zu deren herstellung und verwendungen als arzneimittel mit spezifischer, biologischer wirkung

Info

Publication number
ATE305942T1
ATE305942T1 AT98959962T AT98959962T ATE305942T1 AT E305942 T1 ATE305942 T1 AT E305942T1 AT 98959962 T AT98959962 T AT 98959962T AT 98959962 T AT98959962 T AT 98959962T AT E305942 T1 ATE305942 T1 AT E305942T1
Authority
AT
Austria
Prior art keywords
groups
equal
specific biological
homogeneity
dextran derivatives
Prior art date
Application number
AT98959962T
Other languages
English (en)
Inventor
Frederic Chaubet
Remi Huynh
Latifa Dahri
Jose Correia
Marcel Jozefowicz
Jacqueline Jozefonvicz
Original Assignee
Biodex
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Biodex filed Critical Biodex
Application granted granted Critical
Publication of ATE305942T1 publication Critical patent/ATE305942T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C08B37/0006—Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid
    • C08B37/0009—Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid alpha-D-Glucans, e.g. polydextrose, alternan, glycogen; (alpha-1,4)(alpha-1,6)-D-Glucans; (alpha-1,3)(alpha-1,4)-D-Glucans, e.g. isolichenan or nigeran; (alpha-1,4)-D-Glucans; (alpha-1,3)-D-Glucans, e.g. pseudonigeran; Derivatives thereof
    • C08B37/0021—Dextran, i.e. (alpha-1,4)-D-glucan; Derivatives thereof, e.g. Sephadex, i.e. crosslinked dextran
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Polymers & Plastics (AREA)
  • Materials Engineering (AREA)
  • Veterinary Medicine (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
AT98959962T 1997-12-11 1998-12-11 Dextranderivate, verfahren zu deren herstellung und verwendungen als arzneimittel mit spezifischer, biologischer wirkung ATE305942T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR9715702A FR2772382B1 (fr) 1997-12-11 1997-12-11 Derives de dextrane, leur procede de preparation et leurs applications comme medicaments a action biologique specifique
PCT/FR1998/002699 WO1999029734A1 (fr) 1997-12-11 1998-12-11 Derives de dextrane, leur procede de preparation et leurs applications comme medicaments a action biologique specifique

Publications (1)

Publication Number Publication Date
ATE305942T1 true ATE305942T1 (de) 2005-10-15

Family

ID=9514480

Family Applications (1)

Application Number Title Priority Date Filing Date
AT98959962T ATE305942T1 (de) 1997-12-11 1998-12-11 Dextranderivate, verfahren zu deren herstellung und verwendungen als arzneimittel mit spezifischer, biologischer wirkung

Country Status (9)

Country Link
US (1) US6646120B1 (de)
EP (1) EP0990002B1 (de)
JP (1) JP2001523300A (de)
AT (1) ATE305942T1 (de)
AU (1) AU1567799A (de)
CA (1) CA2280949C (de)
DE (1) DE69831805T2 (de)
FR (1) FR2772382B1 (de)
WO (1) WO1999029734A1 (de)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2794649B1 (fr) * 1999-06-11 2003-04-11 Solutions Biomateriau a base d'un derive de dextrane insolubilise et d'un facteur de croissance, son procede de preparation et ses applications
FR2794976B1 (fr) * 1999-06-16 2004-05-07 Solutions Compositions pharmaceutiques a action cicatrisante ou anti-complementaire comprenant un derive de dextrane
DE10064827A1 (de) 2000-12-22 2002-06-27 Dade Behring Marburg Gmbh Nachweisverfahren
FR2832708B1 (fr) * 2001-11-29 2004-02-13 Organes Tissus Regeneration Re Procede de sulfonation de composes comprenant des groupements hydroxyle (oh) libres ou des amines primaires ou secondaires
US7172906B2 (en) * 2004-11-16 2007-02-06 Dade Behring Inc. Reduction of non-specific binding in assays
FR2914305B1 (fr) * 2007-03-29 2009-07-03 Proteins & Peptides Man Dextran fonctionnalise par des amino-acides hydrophobes.
FR2891149B1 (fr) 2005-09-26 2007-11-30 Biodex Sarl Composition pharmaceutique a action cicatrisante comprenant un derive de dextrane soluble et un facteur de croissance derive des plaquettes.
CN101460523A (zh) * 2006-04-07 2009-06-17 阿道恰公司 双官能化多糖
FR2914191A1 (fr) * 2007-03-29 2008-10-03 Proteins & Peptides Man Composition angiogenique.
FR2919188B1 (fr) * 2007-07-27 2010-02-26 Proteins & Peptides Man Complexes entre un polymere amphiphile et une proteine osteogenique appartenant a la famille des bmps
FR2934999B1 (fr) * 2008-08-13 2011-07-29 Adocia Polysaccharides fonctionnalises par des derives du tryptophane
FR2966248B1 (fr) 2010-10-18 2020-05-01 Centre National De La Recherche Scientifique (Cnrs) Procede de fonctionnalisation de surfaces pour la detection d'analytes
CN102863550B (zh) * 2012-10-25 2014-06-18 西南大学 辛烯基琥珀酸魔芋葡甘聚糖酯制备方法
FR3025428A1 (fr) 2014-09-08 2016-03-11 Adocia Composition pharmaceutique stable comprenant du pdgf
SE538503C2 (en) 2014-11-11 2016-08-16 Tx Medic Ab New dextran sulfate
CN107580606B (zh) 2015-04-03 2021-06-08 营养与生物科学美国4公司 凝胶化右旋糖酐醚
JP2018513249A (ja) 2015-04-03 2018-05-24 イー・アイ・デュポン・ドウ・ヌムール・アンド・カンパニーＥ．Ｉ．Ｄｕ Ｐｏｎｔ Ｄｅ Ｎｅｍｏｕｒｓ Ａｎｄ Ｃｏｍｐａｎｙ 酸化デキストラン
MX2019006868A (es) 2016-12-16 2019-09-23 Du Pont Derivados de polisacáridos anfifílicos y composiciones que los comprenden.
EP3810659A1 (de) * 2018-06-20 2021-04-28 DuPont Industrial Biosciences USA, LLC Polysaccharidderivate und zusammensetzungen damit

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1152396B (de) * 1960-01-26 1963-08-08 Bernburg Serum Werk Veb Verfahren zur Herstellung von Natriumsalzen blutgerinnungshemmender Dextranschwefelsaeureester
FR2461724A1 (fr) * 1979-07-20 1981-02-06 Christine Fougnot Polymeres substitues par des groupes leur conferant des proprietes anti-coagulantes et leur procede de preparation, objets constitues par et/ou comprenant lesdits polymeres et leurs procedes de fabrication, application desdits objets en chirurgie et en medecine, et compositions pharmaceutiques contenant lesdits polymeres substitues
FR2555589B1 (fr) * 1983-11-30 1986-05-16 Choay Sa Nouveaux derives du dextrane a activites anticoagulante en anti-inflammatoire, leur procede de preparation et utilisation de ces derives en tant qu'anticoagulants et en tant que substituts du plasma sanguin
FR2644066B1 (fr) * 1989-03-09 1994-05-13 Therapeutiques Substitutives Compositions stabilisees comprenant des fgfs, leur procede d'obtention et leurs applications therapeutiques, chirurgicales et cosmetologiques
FR2651436B1 (fr) * 1989-09-05 1994-09-09 Sanofi Sa Compositions pharmaceutiques contenant un derive substitue soluble de dextrane.
FR2657782B1 (fr) * 1990-02-06 1992-05-22 Therapeutiques Substitutives Nouvel agent antitumoral derive du dextrane.

Also Published As

Publication number Publication date
DE69831805D1 (de) 2006-02-16
AU1567799A (en) 1999-06-28
WO1999029734A1 (fr) 1999-06-17
US6646120B1 (en) 2003-11-11
FR2772382A1 (fr) 1999-06-18
EP0990002A1 (de) 2000-04-05
CA2280949A1 (fr) 1999-06-17
DE69831805T2 (de) 2008-01-24
CA2280949C (fr) 2011-03-22
FR2772382B1 (fr) 2000-03-03
JP2001523300A (ja) 2001-11-20
EP0990002B1 (de) 2005-10-05

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