ATE306253T1 - Orale bioadhäsive tablette mit verlängerter wirkstoffabgabe - Google Patents

Orale bioadhäsive tablette mit verlängerter wirkstoffabgabe

Info

Publication number
ATE306253T1
ATE306253T1 AT99942454T AT99942454T ATE306253T1 AT E306253 T1 ATE306253 T1 AT E306253T1 AT 99942454 T AT99942454 T AT 99942454T AT 99942454 T AT99942454 T AT 99942454T AT E306253 T1 ATE306253 T1 AT E306253T1
Authority
AT
Austria
Prior art keywords
extended release
bioadhesive tablet
oral bioadhesive
oral
tablet
Prior art date
Application number
AT99942454T
Other languages
English (en)
Inventor
William J Bologna
Howard L Levine
Philippe Cartier
Ziegler Dominique De
Original Assignee
Columbia Lab Bermuda Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=22265404&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ATE306253(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Columbia Lab Bermuda Ltd filed Critical Columbia Lab Bermuda Ltd
Application granted granted Critical
Publication of ATE306253T1 publication Critical patent/ATE306253T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • A61K31/568—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in positions 10 and 13 by a chain having at least one carbon atom, e.g. androstanes, e.g. testosterone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0034—Urogenital system, e.g. vagina, uterus, cervix, penis, scrotum, urethra, bladder; Personal lubricants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/006—Oral mucosa, e.g. mucoadhesive forms, sublingual droplets; Buccal patches or films; Buccal sprays
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/10—Drugs for genital or sexual disorders; Contraceptives for impotence
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
    • A61P5/26—Androgens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2013—Organic compounds, e.g. phospholipids, fats
    • A61K9/2018—Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/2027—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2059—Starch, including chemically or physically modified derivatives; Amylose; Amylopectin; Dextrin

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Gynecology & Obstetrics (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Reproductive Health (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Pulmonology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Endocrinology (AREA)
  • Rheumatology (AREA)
  • Cardiology (AREA)
  • Diabetes (AREA)
  • Vascular Medicine (AREA)
  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
AT99942454T 1998-08-25 1999-08-24 Orale bioadhäsive tablette mit verlängerter wirkstoffabgabe ATE306253T1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US9784398P 1998-08-25 1998-08-25
US09/379,310 US6248358B1 (en) 1998-08-25 1999-08-23 Bioadhesive progressive hydration tablets and methods of making and using the same
PCT/US1999/019260 WO2000010536A1 (en) 1998-08-25 1999-08-24 Extended release buccal bioadhesive tablet

Publications (1)

Publication Number Publication Date
ATE306253T1 true ATE306253T1 (de) 2005-10-15

Family

ID=22265404

Family Applications (1)

Application Number Title Priority Date Filing Date
AT99942454T ATE306253T1 (de) 1998-08-25 1999-08-24 Orale bioadhäsive tablette mit verlängerter wirkstoffabgabe

Country Status (25)

Country Link
US (1) US6248358B1 (de)
EP (1) EP1105104B1 (de)
JP (2) JP5411398B2 (de)
KR (1) KR100716702B1 (de)
CN (2) CN1879608A (de)
AR (1) AR036972A1 (de)
AT (1) ATE306253T1 (de)
AU (1) AU754880B2 (de)
BR (1) BR9913239B1 (de)
CA (1) CA2341375C (de)
DE (1) DE69927694T2 (de)
DK (1) DK1105104T3 (de)
ES (1) ES2251220T3 (de)
HU (1) HU226591B1 (de)
IL (1) IL141445A (de)
MA (1) MA24964A1 (de)
MX (1) MXPA01002007A (de)
MY (2) MY125919A (de)
NO (1) NO331255B1 (de)
NZ (1) NZ509963A (de)
PE (1) PE20001036A1 (de)
RU (1) RU2227022C2 (de)
UA (1) UA78967C2 (de)
WO (1) WO2000010536A1 (de)
ZA (1) ZA995445B (de)

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ZA995445B (en) 2000-11-27
IL141445A (en) 2005-12-18
JP2010248231A (ja) 2010-11-04
EP1105104B1 (de) 2005-10-12
EP1105104A1 (de) 2001-06-13
NO20010919D0 (no) 2001-02-23
AU5582699A (en) 2000-03-14
HK1034895A1 (en) 2001-11-09
KR100716702B1 (ko) 2007-05-14
UA78967C2 (uk) 2007-05-10
MXPA01002007A (es) 2002-06-04
BR9913239A (pt) 2001-05-15
CA2341375C (en) 2006-07-11
NO20010919L (no) 2001-03-22
JP5411398B2 (ja) 2014-02-12
HU226591B1 (en) 2009-04-28
WO2000010536A8 (en) 2000-06-15
BR9913239B1 (pt) 2010-11-16
DK1105104T3 (da) 2006-02-06
HUP0103218A2 (hu) 2001-12-28
DE69927694T2 (de) 2006-08-10
CA2341375A1 (en) 2000-03-02
JP2004500317A (ja) 2004-01-08
MY125919A (en) 2006-08-30
RU2227022C2 (ru) 2004-04-20
WO2000010536A9 (en) 2000-08-24
ES2251220T3 (es) 2006-04-16
CN1879608A (zh) 2006-12-20
MY133365A (en) 2007-11-30
MA24964A1 (fr) 2000-04-01
US6248358B1 (en) 2001-06-19
AU754880B2 (en) 2002-11-28
AR036972A1 (es) 2004-10-20
CN1259903C (zh) 2006-06-21
NZ509963A (en) 2004-11-26
KR20010072924A (ko) 2001-07-31
DE69927694D1 (de) 2005-11-17
PE20001036A1 (es) 2000-10-12
IL141445A0 (en) 2002-03-10
NO331255B1 (no) 2011-11-07
CN1323201A (zh) 2001-11-21
WO2000010536A1 (en) 2000-03-02

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