ATE307335T1 - Verfahren zum nachweis von änderungen in morphologischen zellparametern - Google Patents
Verfahren zum nachweis von änderungen in morphologischen zellparameternInfo
- Publication number
- ATE307335T1 ATE307335T1 AT03718967T AT03718967T ATE307335T1 AT E307335 T1 ATE307335 T1 AT E307335T1 AT 03718967 T AT03718967 T AT 03718967T AT 03718967 T AT03718967 T AT 03718967T AT E307335 T1 ATE307335 T1 AT E307335T1
- Authority
- AT
- Austria
- Prior art keywords
- population
- cells
- sub
- wavelength
- light
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 4
- 230000000877 morphologic effect Effects 0.000 title abstract 4
- 230000001413 cellular effect Effects 0.000 abstract 3
- 239000003550 marker Substances 0.000 abstract 3
- 239000000126 substance Substances 0.000 abstract 2
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 238000001514 detection method Methods 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 238000005286 illumination Methods 0.000 abstract 1
- 238000002372 labelling Methods 0.000 abstract 1
- 238000012216 screening Methods 0.000 abstract 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
- G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
- G01N33/502—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing non-proliferative effects
- G01N33/5026—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing non-proliferative effects on cell morphology
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
- G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
- G01N33/582—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances with fluorescent label
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/968—High energy substrates, e.g. fluorescent, chemiluminescent, radioactive
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Immunology (AREA)
- Chemical & Material Sciences (AREA)
- Hematology (AREA)
- Urology & Nephrology (AREA)
- Molecular Biology (AREA)
- Cell Biology (AREA)
- General Health & Medical Sciences (AREA)
- Pathology (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- General Physics & Mathematics (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Toxicology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Physiology (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
- Investigating Or Analysing Materials By Optical Means (AREA)
- Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
- Magnetic Resonance Imaging Apparatus (AREA)
- Measuring Pulse, Heart Rate, Blood Pressure Or Blood Flow (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB0211072.4A GB0211072D0 (en) | 2002-05-15 | 2002-05-15 | Reagent and method for the determination of changes in a cellular morphological parameter |
| PCT/GB2003/001904 WO2003098210A1 (en) | 2002-05-15 | 2003-05-07 | Method for the determination of changes in a cellular morphological parameter |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE307335T1 true ATE307335T1 (de) | 2005-11-15 |
Family
ID=9936674
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT03718967T ATE307335T1 (de) | 2002-05-15 | 2003-05-07 | Verfahren zum nachweis von änderungen in morphologischen zellparametern |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US7527940B2 (de) |
| EP (1) | EP1504259B1 (de) |
| JP (1) | JP4498919B2 (de) |
| KR (1) | KR20050007539A (de) |
| CN (1) | CN100507562C (de) |
| AT (1) | ATE307335T1 (de) |
| AU (1) | AU2003223001B2 (de) |
| CA (1) | CA2485659C (de) |
| DE (1) | DE60301959T2 (de) |
| DK (1) | DK1504259T3 (de) |
| ES (1) | ES2250885T3 (de) |
| GB (1) | GB0211072D0 (de) |
| IL (1) | IL164843A0 (de) |
| WO (1) | WO2003098210A1 (de) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2006104201A1 (ja) * | 2005-03-29 | 2006-10-05 | Olympus Corporation | 細胞画像解析方法、細胞画像解析プログラム、細胞画像解析装置、スクリーニング方法およびスクリーニング装置 |
| RU2305270C2 (ru) * | 2005-05-18 | 2007-08-27 | Андрей Алексеевич Климов | Способ флуоресцентной наноскопии (варианты) |
| WO2007030835A2 (en) * | 2005-09-10 | 2007-03-15 | Baer Stephen C | High resolution microscopy using an optically switchable fluorophore |
| CN101226190B (zh) * | 2007-01-17 | 2013-07-03 | 深圳迈瑞生物医疗电子股份有限公司 | 流式细胞术的自动分类方法和装置 |
| JP2010207133A (ja) * | 2009-03-10 | 2010-09-24 | Sony Corp | 細胞分離方法 |
| EP2483684B1 (de) * | 2009-10-02 | 2018-04-18 | Blanchette Rockefeller Neurosciences, Institute | Fibroblast wachstumsmuster zur diagnose der alzheimer-krankheit |
| US9134301B2 (en) * | 2010-11-22 | 2015-09-15 | Bio-Rad Laboratories, Inc. | Sorting of adherent cells by selective transformation of labels |
| WO2018012601A1 (ja) * | 2016-07-14 | 2018-01-18 | 大日本印刷株式会社 | 画像解析システム、培養管理システム、画像解析方法、培養管理方法、細胞群製造方法及びプログラム |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5635608A (en) * | 1994-11-08 | 1997-06-03 | Molecular Probes, Inc. | α-carboxy caged compounds |
| US5989835A (en) * | 1997-02-27 | 1999-11-23 | Cellomics, Inc. | System for cell-based screening |
| US5885840A (en) * | 1997-02-10 | 1999-03-23 | Compucyte Corp. | Multiple assays of cell specimens |
| US6416959B1 (en) * | 1997-02-27 | 2002-07-09 | Kenneth Giuliano | System for cell-based screening |
| KR100560588B1 (ko) * | 1998-03-16 | 2006-03-16 | 에머샘 바이오사이언시즈 코프 | 공초점 마이크로스코피 영상 시스템 |
| US6986993B1 (en) * | 1999-08-05 | 2006-01-17 | Cellomics, Inc. | System for cell-based screening |
| JP2003506711A (ja) * | 1999-08-05 | 2003-02-18 | セロミックス インコーポレイテッド | 光学システムによる細胞の解析 |
| CA2353120A1 (en) * | 2001-07-16 | 2003-01-16 | Cardiogenics Inc. | Caged compound cleaving process |
| US6933154B2 (en) * | 2002-07-09 | 2005-08-23 | Medispectra, Inc. | Optimal windows for obtaining optical data for characterization of tissue samples |
-
2002
- 2002-05-15 GB GBGB0211072.4A patent/GB0211072D0/en not_active Ceased
-
2003
- 2003-05-07 AT AT03718967T patent/ATE307335T1/de not_active IP Right Cessation
- 2003-05-07 CN CNB038107260A patent/CN100507562C/zh not_active Expired - Fee Related
- 2003-05-07 US US10/514,924 patent/US7527940B2/en not_active Expired - Fee Related
- 2003-05-07 ES ES03718967T patent/ES2250885T3/es not_active Expired - Lifetime
- 2003-05-07 WO PCT/GB2003/001904 patent/WO2003098210A1/en not_active Ceased
- 2003-05-07 DK DK03718967T patent/DK1504259T3/da active
- 2003-05-07 JP JP2004505685A patent/JP4498919B2/ja not_active Expired - Fee Related
- 2003-05-07 AU AU2003223001A patent/AU2003223001B2/en not_active Ceased
- 2003-05-07 EP EP03718967A patent/EP1504259B1/de not_active Expired - Lifetime
- 2003-05-07 DE DE60301959T patent/DE60301959T2/de not_active Expired - Lifetime
- 2003-05-07 KR KR10-2004-7018283A patent/KR20050007539A/ko not_active Withdrawn
- 2003-05-07 CA CA2485659A patent/CA2485659C/en not_active Expired - Fee Related
-
2004
- 2004-10-26 IL IL16484304A patent/IL164843A0/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| DK1504259T3 (da) | 2006-03-06 |
| AU2003223001A1 (en) | 2003-12-02 |
| JP4498919B2 (ja) | 2010-07-07 |
| IL164843A0 (en) | 2005-12-18 |
| CA2485659A1 (en) | 2003-11-27 |
| US20050227310A1 (en) | 2005-10-13 |
| EP1504259A1 (de) | 2005-02-09 |
| GB0211072D0 (en) | 2002-06-26 |
| CN1653331A (zh) | 2005-08-10 |
| US7527940B2 (en) | 2009-05-05 |
| CN100507562C (zh) | 2009-07-01 |
| KR20050007539A (ko) | 2005-01-19 |
| CA2485659C (en) | 2011-04-19 |
| DE60301959D1 (de) | 2006-03-02 |
| WO2003098210A1 (en) | 2003-11-27 |
| JP2005525127A (ja) | 2005-08-25 |
| AU2003223001B2 (en) | 2006-08-10 |
| ES2250885T3 (es) | 2006-04-16 |
| DE60301959T2 (de) | 2006-07-27 |
| EP1504259B1 (de) | 2005-10-19 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| ES2527210T3 (es) | Células etiquetadas para su uso como un control interno funcional en ensayos de detección de células raras | |
| RU2003100531A (ru) | Композиции, содержащие краситель на основе производного мочевины, для выявления аналита, и способы их использования | |
| ATE426835T1 (de) | Verfahren zur inspektion von wafern und retikeln unter verwendung von entwickler-absichtsdaten | |
| DE60025400D1 (de) | Vorrichtung und verfahren zum kalibrieren eines abtastsystems für mikroarrays | |
| CN101634551A (zh) | 一种检测表面粗糙度的方法及其系统 | |
| ATE272841T1 (de) | Versuchsanordnung mit erweiterter bandbreite | |
| DE60332639D1 (de) | Verwendung von biomarkern zum nachweis von eierstockkrebs | |
| JP2004503760A5 (de) | ||
| SG125922A1 (en) | Device inspection | |
| WO2001096840A3 (en) | High sensitivity optical inspection system and method for detecting flaws on a diffractive surface | |
| BR9810263A (pt) | Processo para avaliar artigos absorventes | |
| PT1095270E (pt) | Dispositivo de rastreio e metodo de rastreio de um teste de imunoensaio | |
| ES2122950T1 (es) | Aparato de auto calibrado del sistema de analisis biologico. | |
| CO5280171A1 (es) | Procesos de control que tienen multiples detecciones | |
| ATE483157T1 (de) | Vorrichtung und verfahren zur automatischen inspektion von materialbahnen | |
| DK1071809T3 (da) | Multiparameter FACS test til påvisning af ændringer i cellulære parametre | |
| ATE423972T1 (de) | Vorrichtung und verfahren um gleichzeitig verschiedene antikörper und antigene nachzuweisen in klinischen, nahrungsmittel- und umwelt-proben | |
| DE60301959D1 (de) | Verfahren zum nachweis von änderungen in morphologischen zellparametern | |
| DE602004006764D1 (de) | Verfahren zur Bestimmung der Identität einer unbekannten Nachbarzelle und Vorrichtung dafür | |
| ATE449319T1 (de) | Verfahren und vorrichtung zur messung von wellenfronten | |
| DE60331918D1 (de) | Verfahren und vorrichtung zur messung der anzahl weisser blutzellen | |
| WO2003043064A1 (fr) | Dispositif de controle d'un substrat, dispositif de revetement/mise au point, et dispositif de controle d'un substrat | |
| DE69623650D1 (de) | Verfahren zum testen einer zellprobe | |
| ES2120169T3 (es) | Ensayo de retro-titulacion utilizando dos marcadores diferentes. | |
| WO2023004204A3 (en) | Use of circulating cell-free methylated dna to detect tissue damage |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |