ATE308042T1 - Vorrichtung und verfahren für die trennung von analyten - Google Patents

Vorrichtung und verfahren für die trennung von analyten

Info

Publication number
ATE308042T1
ATE308042T1 AT02772306T AT02772306T ATE308042T1 AT E308042 T1 ATE308042 T1 AT E308042T1 AT 02772306 T AT02772306 T AT 02772306T AT 02772306 T AT02772306 T AT 02772306T AT E308042 T1 ATE308042 T1 AT E308042T1
Authority
AT
Austria
Prior art keywords
compartments
compounds
analyte solution
separation
solution
Prior art date
Application number
AT02772306T
Other languages
English (en)
Inventor
Philippe Michel
Frederic Reymond
Joel Stephane Rossier
Original Assignee
Diagnoswiss Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Diagnoswiss Sa filed Critical Diagnoswiss Sa
Application granted granted Critical
Publication of ATE308042T1 publication Critical patent/ATE308042T1/de

Links

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/26Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
    • G01N27/416Systems
    • G01N27/447Systems using electrophoresis
    • G01N27/44756Apparatus specially adapted therefor
    • G01N27/44795Isoelectric focusing
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/26Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
    • G01N27/416Systems
    • G01N27/447Systems using electrophoresis
    • G01N27/44756Apparatus specially adapted therefor
    • G01N27/44773Multi-stage electrophoresis, e.g. two-dimensional electrophoresis

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Molecular Biology (AREA)
  • Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Electrochemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Peptides Or Proteins (AREA)
  • Electrostatic Separation (AREA)
  • Sampling And Sample Adjustment (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
AT02772306T 2001-08-31 2002-08-30 Vorrichtung und verfahren für die trennung von analyten ATE308042T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB0121189.5A GB0121189D0 (en) 2001-08-31 2001-08-31 Apparatus and method for separating an analyte
PCT/EP2002/010369 WO2003019172A2 (en) 2001-08-31 2002-08-30 Apparatus and method for separating an analyte

Publications (1)

Publication Number Publication Date
ATE308042T1 true ATE308042T1 (de) 2005-11-15

Family

ID=9921346

Family Applications (1)

Application Number Title Priority Date Filing Date
AT02772306T ATE308042T1 (de) 2001-08-31 2002-08-30 Vorrichtung und verfahren für die trennung von analyten

Country Status (7)

Country Link
US (1) US7390389B2 (de)
EP (1) EP1421373B1 (de)
JP (1) JP4227016B2 (de)
AT (1) ATE308042T1 (de)
DE (1) DE60206937T2 (de)
GB (1) GB0121189D0 (de)
WO (1) WO2003019172A2 (de)

Families Citing this family (49)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6803568B2 (en) 2001-09-19 2004-10-12 Predicant Biosciences, Inc. Multi-channel microfluidic chip for electrospray ionization
US7105810B2 (en) 2001-12-21 2006-09-12 Cornell Research Foundation, Inc. Electrospray emitter for microfluidic channel
GB0226160D0 (en) * 2002-11-08 2002-12-18 Diagnoswiss Sa Apparatus for dispensing a sample in electrospray mass spectrometers
GB0300820D0 (en) * 2003-01-14 2003-02-12 Diagnoswiss Sa Membrane-microchannel strip
US7007710B2 (en) 2003-04-21 2006-03-07 Predicant Biosciences, Inc. Microfluidic devices and methods
AU2004272746B2 (en) * 2003-09-15 2009-12-03 Diagnoswiss S.A. Microfluidic flow monitoring device
JP2007524069A (ja) * 2003-09-24 2007-08-23 アジレント・テクノロジーズ・インク フレームを使用した分子の抽出
US7537807B2 (en) 2003-09-26 2009-05-26 Cornell University Scanned source oriented nanofiber formation
US8518228B2 (en) 2011-05-20 2013-08-27 The University Of British Columbia Systems and methods for enhanced SCODA
US10337054B2 (en) 2004-02-02 2019-07-02 Quantum-Si Incorporated Enrichment of nucleic acid targets
US9186685B2 (en) 2012-01-13 2015-11-17 The University Of British Columbia Multiple arm apparatus and methods for separation of particles
US8529744B2 (en) 2004-02-02 2013-09-10 Boreal Genomics Corp. Enrichment of nucleic acid targets
EP1720636A4 (de) 2004-02-02 2012-06-20 Univ British Columbia Scodaphorese und verfahren und vorrichtungen zum bewegen und aufkonzentrieren von teilchen
US20060060769A1 (en) 2004-09-21 2006-03-23 Predicant Biosciences, Inc. Electrospray apparatus with an integrated electrode
US7591883B2 (en) 2004-09-27 2009-09-22 Cornell Research Foundation, Inc. Microfiber supported nanofiber membrane
US20070240986A1 (en) * 2004-11-12 2007-10-18 Diagnoswiss S.A. Microfluidic Device with Minimized Ohmic Resistance
WO2006063625A1 (en) * 2004-12-17 2006-06-22 Agilent Technologies, Inc. Fractionation using electro elution
CA2496294A1 (en) 2005-02-07 2006-08-07 The University Of British Columbia Apparatus and methods for concentrating and separating particles such as molecules
EP1669751B1 (de) * 2005-07-07 2007-12-12 Agilent Technologies, Inc. Modulares System für Gelelektrophoresegerät
WO2007051492A1 (en) 2005-11-02 2007-05-10 Agilent Technologies, Inc. Force-promoted sample recovery in gel electrophoresis
GB0607205D0 (en) * 2006-04-10 2006-05-17 Diagnoswiss Sa Miniaturised biosensor with optimized anperimetric detection
WO2007141692A1 (en) * 2006-06-02 2007-12-13 Koninklijke Philips Electronics N. V. Separation device for isoelectric focusing
EP2193100B1 (de) * 2007-08-27 2014-05-07 Technion Research and Development Foundation, Limited Durch Elektrolyse gesteuerte pH-Gradienten und ihre Verwendung bei der isoelektrischen Fokussierung
CA2713313A1 (en) 2008-02-01 2009-08-06 The University Of British Columbia Methods and apparatus for particle introduction and recovery
EP2146200A1 (de) 2008-07-16 2010-01-20 Agilent Technologies, Inc. Vorrichtung und Verfahren zur isoelektrischen Fokussierung
US8877028B2 (en) 2009-04-21 2014-11-04 The University Of British Columbia System and methods for detection of particles
CN101556261B (zh) * 2009-05-25 2012-01-11 北京理工大学 微管内等电聚焦和剪断吹出培养测定微生物等电点的方法
US9028664B2 (en) * 2009-08-18 2015-05-12 Technion Research & Development Foundation Limited Proton concentration topographies, methods and devices for producing the same
CN102472724B (zh) 2009-08-18 2014-08-13 工业研究与发展基金会有限公司 分离分子分析物的方法和装置
US9855735B2 (en) 2009-11-23 2018-01-02 Cyvek, Inc. Portable microfluidic assay devices and methods of manufacture and use
WO2013133899A1 (en) 2012-03-08 2013-09-12 Cyvek, Inc Microfluidic assay systems employing micro-particles and methods of manufacture
US9759718B2 (en) 2009-11-23 2017-09-12 Cyvek, Inc. PDMS membrane-confined nucleic acid and antibody/antigen-functionalized microlength tube capture elements, and systems employing them, and methods of their use
US9651568B2 (en) 2009-11-23 2017-05-16 Cyvek, Inc. Methods and systems for epi-fluorescent monitoring and scanning for microfluidic assays
US10065403B2 (en) 2009-11-23 2018-09-04 Cyvek, Inc. Microfluidic assay assemblies and methods of manufacture
US9700889B2 (en) * 2009-11-23 2017-07-11 Cyvek, Inc. Methods and systems for manufacture of microarray assay systems, conducting microfluidic assays, and monitoring and scanning to obtain microfluidic assay results
US9216412B2 (en) 2009-11-23 2015-12-22 Cyvek, Inc. Microfluidic devices and methods of manufacture and use
US9500645B2 (en) 2009-11-23 2016-11-22 Cyvek, Inc. Micro-tube particles for microfluidic assays and methods of manufacture
US9766207B2 (en) 2011-11-04 2017-09-19 Bio-Rad Laboratories, Inc. Affinity methods and compositions employing electronic control of pH
WO2013067509A1 (en) 2011-11-04 2013-05-10 Bio-Rad Laboratories, Inc. Simultaneous purification of cell components
EP2773959B1 (de) * 2011-11-04 2019-04-10 Bio-Rad Laboratories, Inc. Proteinfraktionierung durch isoelektrische fokussierung
WO2013123425A1 (en) 2012-02-15 2013-08-22 Bio-Rad Laboratories, Inc. Electronic control of ph and ionic strength
US9321012B2 (en) 2012-04-04 2016-04-26 Bio-Rad Laboratories, Inc. Electronic protein fractionation
WO2013166444A2 (en) 2012-05-04 2013-11-07 Boreal Genomics Corp. Biomarker analysis using scodaphoresis
US9340835B2 (en) 2013-03-15 2016-05-17 Boreal Genomics Corp. Method for separating homoduplexed and heteroduplexed nucleic acids
US11130986B2 (en) 2015-05-20 2021-09-28 Quantum-Si Incorporated Method for isolating target nucleic acid using heteroduplex binding proteins
CN106582289B (zh) * 2015-10-16 2021-02-05 中美华世通生物医药科技(武汉)有限公司 过滤系统和过滤方法
US10228367B2 (en) 2015-12-01 2019-03-12 ProteinSimple Segmented multi-use automated assay cartridge
CN107245093A (zh) * 2017-08-09 2017-10-13 赖兵 一种蛋白质等电纯化装置及方法
WO2021086985A1 (en) 2019-10-29 2021-05-06 Quantum-Si Incorporated Peristaltic pumping of fluids and associated methods, systems, and devices

Family Cites Families (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2815320A (en) * 1953-10-23 1957-12-03 Kollsman Paul Method of and apparatus for treating ionic fluids by dialysis
DE2051715B2 (de) 1970-10-21 1976-01-15 Trennkammer fuer die kontinuierliche ablenkungselektrophorese
US3719580A (en) * 1971-06-04 1973-03-06 R Roberts Electrophoretic apparatus
GB1422118A (en) 1972-01-04 1976-01-21 Bovril Ltd Vertical gel electrophoresis apparatus
US3888758A (en) * 1973-06-28 1975-06-10 Sheik Arshad Saeed Apparatus for large scale gel electrophoresis
US4148703A (en) * 1976-02-11 1979-04-10 Morton Weintraub Method of electrophoretic purification of enzymes and peptides by means of an adjustable, specialized, geometrically located electrode system
US4362612A (en) * 1978-04-18 1982-12-07 University Patents, Inc. Isoelectric focusing apparatus
CA1238296A (en) 1984-08-02 1988-06-21 Claude Hamelin Electrophoresis system for multiple agarose slab gels
EP0287513B1 (de) * 1987-04-11 1992-12-02 Ciba-Geigy Ag Isoelektrisches Fokussierverfahren sowie Einrichtung zur Durchführung dieses Verfahrens
US5114555A (en) * 1988-01-05 1992-05-19 Monsanto Company Continuous isoelectric separation
US5126022A (en) * 1990-02-28 1992-06-30 Soane Tecnologies, Inc. Method and device for moving molecules by the application of a plurality of electrical fields
US5104512A (en) 1990-05-14 1992-04-14 Labintelligence, Inc. Gel electrophoresis system
US5149418A (en) * 1991-09-04 1992-09-22 Apogee Designs, Ltd. Vertical gel electrophoresis apparatus having universal gel assembly support structure
FI119756B (fi) * 1995-01-18 2009-03-13 Alteon Inc Tiatsoliumyhdisteiden käyttö pitkälle edenneen glykosylaation lopputuotteiden muodostumisen estossa ja suunnan muutoksessa
IT1272932B (it) * 1995-01-24 1997-07-01 Pier Giorgio Righetti Reattore ad enzima immobilizzato
US5540826A (en) * 1995-03-15 1996-07-30 Protein Technologies, Inc. Multi-channel separation device
CA2192262C (en) 1995-12-08 2011-03-15 Yoshihide Hayashizaki Method for purification and transfer to separation/detection systems of dna sequencing samples and plates used therefor
US5773645A (en) * 1997-05-05 1998-06-30 Bio-Rad Laboratories, Inc. Two-dimensional electrophoresis device
US6013165A (en) * 1998-05-22 2000-01-11 Lynx Therapeutics, Inc. Electrophoresis apparatus and method
AUPP576598A0 (en) * 1998-09-07 1998-10-01 Life Therapeutics Limited Cassette for macromolecule purification
WO2000074850A2 (en) * 1999-06-03 2000-12-14 University Of Washington Microfluidic devices for transverse electrophoresis and isoelectric focusing
AU3812000A (en) * 2000-03-15 2001-09-24 Proteosys Ag Micropreparative isoelectric focussing
US6638408B1 (en) * 2000-04-03 2003-10-28 The Wistar Institute Method and device for separation of charged molecules by solution isoelectric focusing
GB0010957D0 (en) * 2000-05-05 2000-06-28 Novartis Ag Compound & method
US6706162B1 (en) * 2000-09-25 2004-03-16 Applera Corporation High speed, high resolution compositions, methods, and kits for capillary electrophoresis

Also Published As

Publication number Publication date
WO2003019172A3 (en) 2003-12-18
US7390389B2 (en) 2008-06-24
DE60206937D1 (de) 2005-12-01
EP1421373B1 (de) 2005-10-26
DE60206937T2 (de) 2006-07-27
EP1421373A2 (de) 2004-05-26
GB0121189D0 (en) 2001-10-24
WO2003019172A2 (en) 2003-03-06
US20040231986A1 (en) 2004-11-25
JP2005502864A (ja) 2005-01-27
JP4227016B2 (ja) 2009-02-18

Similar Documents

Publication Publication Date Title
DE60206937D1 (de) Vorrichtung und verfahren für die trennung von analyten
DE3587888D1 (de) Mittel zum Abtrennen von Proteinen aus Blutplasma.
DE58906257D1 (de) Verfahren zur Abtrennung von Störelementen aus Wertmetall-Elektrolytlösungen.
ATE208399T1 (de) Ein verfahren zur reinigung von phosphatidylserin
DE69800049D1 (de) Mehrstufiges Verfahren für die Trennung/rückgewinnung von Gasen
DE3677618D1 (de) Gerinnungsmittel zur trennung von serum oder plasma aus vollblut zur verwendung in blutuntersuchungsmethoden.
DE50003766D1 (de) Verfahren und vorrichtung zum nachweis und zur quantifizierung von biomolekülen
DK1159453T3 (da) Fremgangsmåde til direkte nukleinsyresekventering
MX168497B (es) Ultrafiltracion de flujo tangencial por afinidad
DE3769807D1 (de) Verfahren zur trennung von lipoproteinen.
DE69925090D1 (de) Verfahren zum Rückgewinnen von Phosphat aus Schlamm und System dafür
DE59912722D1 (de) Kontinuierliches verfahren zur trennung von stoffen nach molekülgrösse
ATE554168T1 (de) Integriertes mikrofluidisches bauteil zum aufreinigen von analytmolekülen sowie verfahren zum aufreinigen
GB9810403D0 (en) Separation of nucleic acids
DE68900949D1 (de) Verfahren zur trennung von wasserstoffbehandlungs-ausfluessen.
DE3672838D1 (de) Verfahren zur gewinnung von edelmetallen aus erzkonzentraten.
DE69904971D1 (de) Verfahren zur Abtrennung von Serum aus Vollblut
DE60042343D1 (de) Abtrennung von fibrinogen von plasmaproteasen
ATE340631T1 (de) Verfahren zur isoelektrischen auftrennung mittels ph-wert-voreinstellung
DE3772342D1 (de) Verfahren zur abtrennung von phosphinischen verunreinigungen aus hoeheren olefinen.
DE69932151D1 (de) Verfahren und vorrichtung zum transformieren von plasma
DE59606129D1 (de) Verfahren und verbindungen zur detektion von analyten mittels remanenzmessung und deren verwendung
DE3766830D1 (de) Verfahren zur abtrennung von kohlenwasserstoffen aus abwaessern.
ATE394348T1 (de) Verfahren zur abtrennung von öl, fett und schmierfett aus wasser
ATA151986A (de) Verfahren zur entfernung und rueckgewinnung von ungeloesten organischen stoffen und gegebenenfalls vorliegenden, geloesten organischen stoffen aus wasser

Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties