ATE308614T1 - Durch pflanzen hergestelltes rekombinantes kollagen, verfahren zu ihrer herstellung und verwendung - Google Patents

Durch pflanzen hergestelltes rekombinantes kollagen, verfahren zu ihrer herstellung und verwendung

Info

Publication number
ATE308614T1
ATE308614T1 AT97952089T AT97952089T ATE308614T1 AT E308614 T1 ATE308614 T1 AT E308614T1 AT 97952089 T AT97952089 T AT 97952089T AT 97952089 T AT97952089 T AT 97952089T AT E308614 T1 ATE308614 T1 AT E308614T1
Authority
AT
Austria
Prior art keywords
plants
derived proteins
production
recombinant collagen
collagen produced
Prior art date
Application number
AT97952089T
Other languages
English (en)
Inventor
Veronique Gruber
Jean-Yves Exposito
Florence Ruggiero
Jeanne Comte
Robert Garrone
Bertrand Merot
Philippe Bournat
Original Assignee
Meristem Therapeutics S A
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=9499306&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ATE308614(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Meristem Therapeutics S A filed Critical Meristem Therapeutics S A
Application granted granted Critical
Publication of ATE308614T1 publication Critical patent/ATE308614T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/78—Connective tissue peptides, e.g. collagen, elastin, laminin, fibronectin, vitronectin or cold insoluble globulin [CIG]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
    • C12N15/8242—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits
    • C12N15/8257—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits for the production of primary gene products, e.g. pharmaceutical products, interferon

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biomedical Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Wood Science & Technology (AREA)
  • Biophysics (AREA)
  • Biotechnology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Cell Biology (AREA)
  • Toxicology (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Neurosurgery (AREA)
  • Dermatology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Neurology (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
AT97952089T 1996-12-17 1997-12-17 Durch pflanzen hergestelltes rekombinantes kollagen, verfahren zu ihrer herstellung und verwendung ATE308614T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR9616224A FR2757874B1 (fr) 1996-12-17 1996-12-17 Collagenes recombinants et proteines derivees produits par les plantes, leurs procedes d'obtention et leurs utilisations
PCT/FR1997/002331 WO1998027202A1 (fr) 1996-12-17 1997-12-17 Collagenes recombinants et proteines derivees produits par les plantes, leurs procedes d'obtention et leurs utilisations

Publications (1)

Publication Number Publication Date
ATE308614T1 true ATE308614T1 (de) 2005-11-15

Family

ID=9499306

Family Applications (1)

Application Number Title Priority Date Filing Date
AT97952089T ATE308614T1 (de) 1996-12-17 1997-12-17 Durch pflanzen hergestelltes rekombinantes kollagen, verfahren zu ihrer herstellung und verwendung

Country Status (9)

Country Link
US (2) US6617431B1 (de)
EP (1) EP0951537B1 (de)
JP (1) JP2001507573A (de)
AT (1) ATE308614T1 (de)
AU (1) AU5563798A (de)
CA (1) CA2274807A1 (de)
DE (1) DE69734528T2 (de)
FR (1) FR2757874B1 (de)
WO (1) WO1998027202A1 (de)

Families Citing this family (37)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19834909A1 (de) * 1998-08-03 2000-02-17 Mpb Cologne Gmbh Molecular Pla Faserproteine und ihre Herstellung
EP1177291A2 (de) * 1999-04-30 2002-02-06 Biostratum, Inc. Laminin 8 und methoden zur verwendung
EP1232182B1 (de) * 1999-11-12 2007-10-03 Fibrogen, Inc. Rinder-kollagen und verfahren zur herstelling rekombinantes gelatin
RU2002112751A (ru) * 1999-11-12 2004-02-27 Файброджен, Инк. (Us) Рекомбинантные желатины
AU2005246967B2 (en) * 1999-11-12 2008-09-04 Fibrogen, Inc. Recombinant gelatins
US6992172B1 (en) 1999-11-12 2006-01-31 Fibrogen, Inc. Recombinant gelatins
FR2807436B1 (fr) * 2000-04-10 2002-05-24 Meristem Therapeutics Methode d'obtention de fibres d'un polypeptide collagenique recombinant non-hydroxyle, et fibres de polypeptide collagenique recombinant non-hydroxyle ainsi obtenues
FR2854328B1 (fr) * 2003-04-29 2006-08-04 Rocher Yves Biolog Vegetale Composition cosmetique ou dermatologique ou pharmaceutique contenant un facteur de croissance du type vegetal de nature peptidique
US7268116B2 (en) * 2003-10-02 2007-09-11 Genhunter Corp. Methods and compositions for producing secreted trimeric receptor analogs and biologically active fusion proteins
DE602005023332D1 (de) 2004-09-29 2010-10-14 Collplant Ltd Kollagenproduzierende pflanzen sowie verfahren zu deren erzeugung und verwendung
EP2484768A3 (de) 2005-07-18 2012-11-21 Protalix Ltd. Mukosale oder enterale Verabreichung biologisch aktiver Makromoleküle
ES2661728T3 (es) 2005-10-03 2018-04-03 Pinksky, Mark A. Composiciones y métodos para el cuidado mejorado de la piel
US20080081353A1 (en) * 2006-09-29 2008-04-03 Universite Laval Production of recombinant human collagen
WO2009053985A1 (en) * 2007-10-26 2009-04-30 Collplant Ltd. Methods of processing recombinant procollagen
EP2222270B1 (de) 2007-12-26 2018-11-14 Mark A. Pinsky Collagenformulierungen für verbesserte hautpflege
US9095569B2 (en) 2008-04-18 2015-08-04 Collplant Ltd. Methods of generating and using procollagen
EP2502939B1 (de) 2009-11-19 2016-01-27 Zhejiang University Unnatürliches collagen-artiges protein und seine verwendung
EP2504472A1 (de) 2009-11-24 2012-10-03 Collplant Ltd. Verfahren zur erzeugung von kollagenfasern
US9732321B2 (en) 2010-02-16 2017-08-15 The General Hospital Corporation Engineered craniofacial constructs with composite scaffold
WO2012066543A2 (en) 2010-11-16 2012-05-24 Collplant Ltd. Collagen structures and method of fabricating the same
WO2013093921A1 (en) 2011-12-20 2013-06-27 Collplant Ltd. Collagen coated synthetic polymer fibers
ES2883580T3 (es) 2013-03-21 2021-12-09 Collplant Ltd Composiciones que comprenden colágeno y PRP para la regeneración de tejidos y su método de producción
CN108463470B (zh) 2015-12-23 2021-10-22 菲尼克斯组织修复公司 胶原蛋白7的组合物及其使用方法
US11377490B2 (en) 2017-05-31 2022-07-05 Sichuan Clover Biopharmaceuticals, Inc Method for treating cancer using disulfide-linked trimeric 4-1BBL
KR20200075036A (ko) * 2017-07-18 2020-06-25 모던 메도우 아이엔씨. 생제작된 가죽 물품 및 이의 방법
US11180541B2 (en) 2017-09-28 2021-11-23 Geltor, Inc. Recombinant collagen and elastin molecules and uses thereof
EP3787702B1 (de) 2018-05-03 2024-08-07 CollPlant Ltd. Dermale füllstoffe und deren anwendungen
GB2579036A (en) * 2018-11-15 2020-06-10 Rejuvenated Ltd Compositions comprising amino acids
EP3953380A4 (de) 2019-04-12 2023-01-25 Geltor, Inc. Rekombinantes elastin und herstellung davon
FR3105792B1 (fr) 2019-12-26 2022-08-12 Michel Assor Matériau biocomposite collagène/matrice polymérique poreuse et son utilisation comme implant de réparation de lésions méniscales du genou et/ou de prévention ou de traitement de l’arthrose du genou
GB2610313B (en) 2020-01-24 2024-07-03 Geltor Inc Animal-free dietary collagen
WO2021229577A1 (en) 2020-05-12 2021-11-18 Collplant Ltd. Collagen as a delivery tool for metal-based anti-viral agents
WO2021249011A1 (en) 2020-06-10 2021-12-16 Sichuan Clover Biopharmaceuticals, Inc. Hiv vaccine compositions, methods, and uses thereof
WO2021249116A1 (en) 2020-06-10 2021-12-16 Sichuan Clover Biopharmaceuticals, Inc. Coronavirus vaccine compositions, methods, and uses thereof
WO2022041760A1 (en) 2020-08-31 2022-03-03 Sichuan Clover Biopharmaceuticals, Inc. Methods and compositions for purification of trimeric fusion proteins
WO2023194333A1 (en) 2022-04-04 2023-10-12 Swiftpharma Bv Recombinant spider silk-reinforced collagen proteins produced in plants and the use thereof
WO2026062644A1 (en) 2024-09-20 2026-03-26 Collplant Ltd. Light-absorbing substances suitable for use in additive manufacturing and methods of identification thereof

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4956282A (en) * 1985-07-29 1990-09-11 Calgene, Inc. Mammalian peptide expression in plant cells
US5650554A (en) * 1991-02-22 1997-07-22 Sembiosys Genetics Inc. Oil-body proteins as carriers of high-value peptides in plants
WO1993021320A1 (en) * 1991-02-22 1993-10-28 University Technologies International, Inc. Oil-body proteins as carriers of high-value peptides in plants
JP3302017B2 (ja) * 1991-10-23 2002-07-15 トーマス・ジェファーソン・ユニバーシティ 組み換えｄｎａ合成システムにおけるヒトプロコラーゲン及びコラーゲンの合成
FR2685347A1 (fr) * 1991-12-23 1993-06-25 Univ Pasteur Procede biotechnologique d'obtention et de production microbienne d'oligomeres peptidiques comme substituts de la gelatine.
US5693506A (en) * 1993-11-16 1997-12-02 The Regents Of The University Of California Process for protein production in plants
US6713662B1 (en) * 1994-07-27 2004-03-30 Pharming Intellectual Property B.V. Production of collagen in the milk of transgenic mammals
WO1997004123A1 (en) * 1995-07-19 1997-02-06 Gel Tech Group Inc. Collagen compound production in plants
WO1998006861A2 (en) * 1996-08-15 1998-02-19 Agrivax Incorporated Delivery of tolerogenic antigens via edible plants or plant-derived products

Also Published As

Publication number Publication date
JP2001507573A (ja) 2001-06-12
AU5563798A (en) 1998-07-15
DE69734528D1 (de) 2005-12-08
FR2757874A1 (fr) 1998-07-03
WO1998027202A1 (fr) 1998-06-25
US20030096973A1 (en) 2003-05-22
US6617431B1 (en) 2003-09-09
DE69734528T2 (de) 2006-07-27
FR2757874B1 (fr) 2003-04-25
CA2274807A1 (fr) 1998-06-25
EP0951537B1 (de) 2005-11-02
EP0951537A1 (de) 1999-10-27

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Legal Events

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