ATE152124T1 - Wachstumsfaktor aus parenchymalen lebenszellen, dafür kodierendes gen, verfahren zur herstellung dieses faktors und transformanten - Google Patents

Wachstumsfaktor aus parenchymalen lebenszellen, dafür kodierendes gen, verfahren zur herstellung dieses faktors und transformanten

Info

Publication number
ATE152124T1
ATE152124T1 AT90115397T AT90115397T ATE152124T1 AT E152124 T1 ATE152124 T1 AT E152124T1 AT 90115397 T AT90115397 T AT 90115397T AT 90115397 T AT90115397 T AT 90115397T AT E152124 T1 ATE152124 T1 AT E152124T1
Authority
AT
Austria
Prior art keywords
factor
producing
growth factor
gene coding
parenchymal
Prior art date
Application number
AT90115397T
Other languages
English (en)
Inventor
Naomi Kitamura
Keiji Miyazawa
Yasushi Daikuhara
Hirohito Tsubouchi
Daiji Naka
Kazuhiro Takahashi
Rie Matsui
Yoshiko Yoshiyama
Takehisa Ishii
Original Assignee
Mitsubishi Chem Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=27305852&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ATE152124(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from JP1209449A external-priority patent/JP2577091B2/ja
Priority claimed from JP2088592A external-priority patent/JP3036782B2/ja
Priority claimed from JP2200898A external-priority patent/JP2963163B2/ja
Application filed by Mitsubishi Chem Corp filed Critical Mitsubishi Chem Corp
Application granted granted Critical
Publication of ATE152124T1 publication Critical patent/ATE152124T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475—Growth factors; Growth regulators
    • C07K14/4753—Hepatocyte growth factor; Scatter factor; Tumor cytotoxic factor II
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/10—Cells modified by introduction of foreign genetic material
    • C12N5/12—Fused cells, e.g. hybridomas
    • C12N5/16—Animal cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Biomedical Technology (AREA)
  • Wood Science & Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biophysics (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Toxicology (AREA)
  • Medicinal Chemistry (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Cell Biology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Crystals, And After-Treatments Of Crystals (AREA)
  • Soft Magnetic Materials (AREA)
AT90115397T 1989-08-11 1990-08-10 Wachstumsfaktor aus parenchymalen lebenszellen, dafür kodierendes gen, verfahren zur herstellung dieses faktors und transformanten ATE152124T1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP1209449A JP2577091B2 (ja) 1989-08-11 1989-08-11 肝実質細胞増殖因子及びそれをコードする遺伝子
JP2088592A JP3036782B2 (ja) 1990-04-03 1990-04-03 ヒト肝実質細胞増殖因子の生産方法および該因子を産生する形質転換体
JP2200898A JP2963163B2 (ja) 1990-07-27 1990-07-27 ヒト肝実質細胞増殖因子

Publications (1)

Publication Number Publication Date
ATE152124T1 true ATE152124T1 (de) 1997-05-15

Family

ID=27305852

Family Applications (1)

Application Number Title Priority Date Filing Date
AT90115397T ATE152124T1 (de) 1989-08-11 1990-08-10 Wachstumsfaktor aus parenchymalen lebenszellen, dafür kodierendes gen, verfahren zur herstellung dieses faktors und transformanten

Country Status (7)

Country Link
US (1) US5500354A (de)
EP (1) EP0412557B1 (de)
KR (1) KR960006122B1 (de)
AT (1) ATE152124T1 (de)
CA (1) CA2022752C (de)
DE (2) DE412557T1 (de)
HU (1) HUT58798A (de)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9003621D0 (en) * 1990-02-16 1990-04-11 Imp Cancer Res Tech Protein factor
JP2784455B2 (ja) * 1990-05-09 1998-08-06 敏一 中村 肝硬変治療剤
EP0461560B1 (de) * 1990-06-11 1998-11-18 Toshikazu Nakamura Rekombinanter menschlicher Hepatozytwachstumsfaktor und Verfahren zu seiner Herstellung
JP2750372B2 (ja) * 1990-06-19 1998-05-13 敏一 中村 賢疾患治療剤
DE69131069T2 (de) * 1990-07-13 1999-07-15 Snow Brand Milk Products Co., Ltd., Sapporo, Hokkaido Plasmid das für die aminosäuresequenz von tcf-ii kodierende dns enthalt, transformierte zelle und produktion einer physiologisch aktiven substanz mit ihrer verwendung
JP3200609B2 (ja) * 1990-12-28 2001-08-20 敏一 中村 上皮細胞増殖促進剤
TW318142B (de) * 1991-06-03 1997-10-21 Mitsubishi Chemicals Co Ltd
EP0550296A3 (en) * 1991-11-28 1993-12-29 Terumo Corp Vascular endothelial cells growth factor
US5316921A (en) * 1992-05-18 1994-05-31 Genentech, Inc. Single-chain hepatocyte growth factor variants
ATE222603T1 (de) * 1992-05-18 2002-09-15 Genentech Inc Hepatozytwachstumfaktor variante
US5328837A (en) * 1992-05-18 1994-07-12 Genentech, Inc. Hepatocyte growth factor protease domain variants
CA2102463A1 (en) * 1992-11-05 1994-05-06 Mitsubishi Chemical Corporation Protein and gene encoding said protein
GB9301453D0 (en) * 1993-01-26 1993-03-17 Clonit Spa Nucleotide proves
WO1994021678A1 (fr) * 1993-03-23 1994-09-29 Taisho Pharmaceutical Co., Ltd. Substance de croissance des cellules du parenchyme hepatique
TR200002284T2 (tr) * 1998-02-05 2000-11-21 Smithkline Beecham Biologicals S.A. Mage ailesinden tümör ile ilgili tümör türevleri
WO2001098347A1 (en) * 2000-06-22 2001-12-27 Nippon Zenyaku Kogyo Ltd. Canine liver cell growth factor
KR20020097319A (ko) * 2001-06-20 2002-12-31 윤재승 사람 간세포 성장인자 코딩 벡터, 형질전환 균주 및이로부터 발현된 재조합 단백질
KR100562824B1 (ko) * 2002-03-20 2006-03-23 주식회사 바이로메드 유전자 발현효율이 높으며 간세포 성장인자의 두 가지이형체를 동시에 발현하는 하이브리드 간세포 성장인자유전자
US20090202606A1 (en) * 2008-01-25 2009-08-13 Viromed Co., Ltd. Treatment and Prevention of Cardiac Conditions Using Two or More Isoforms of Hepatocyte Growth Factor
US20090258932A1 (en) * 2008-04-09 2009-10-15 Viromed Co., Ltd. Lyophilized DNA Formulations for Enhanced Expression of Plasmid DNA
WO2012144535A1 (ja) 2011-04-18 2012-10-26 国立大学法人京都大学 急性肝不全抑制剤及びその薬効評価法
KR101779775B1 (ko) 2013-10-22 2017-09-21 주식회사 바이로메드 간세포 성장인자의 둘 이상의 이형체를 이용한 근위축성 측삭 경화증 예방 또는 치료용 조성물
KR101808192B1 (ko) * 2016-08-26 2018-01-18 아미코젠주식회사 7-아미노세팔로스포란산의 고농도 생산 재조합 아크레모니움 크리소제눔 균주의 제조방법 및 이 방법으로 제조된 균주
EP3823677A4 (de) 2018-07-19 2022-06-01 Helixmith Co., Ltd. Lyophilisierte pharmazeutische zusammensetzungen für nackte dna-gentherapie

Also Published As

Publication number Publication date
HU904957D0 (en) 1991-01-28
KR910004803A (ko) 1991-03-29
EP0412557B1 (de) 1997-04-23
HUT58798A (en) 1992-03-30
CA2022752A1 (en) 1991-02-12
EP0412557A1 (de) 1991-02-13
US5500354A (en) 1996-03-19
CA2022752C (en) 1998-07-07
DE412557T1 (de) 1991-07-04
DE69030539T2 (de) 1997-09-11
KR960006122B1 (ko) 1996-05-09
DE69030539D1 (de) 1997-05-28

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RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties