ATE309372T1 - Herstellung von thioesterasen aus pflanzen und offenbarung von thioesterasen aus pflanzen mit neuer substratspezifität - Google Patents
Herstellung von thioesterasen aus pflanzen und offenbarung von thioesterasen aus pflanzen mit neuer substratspezifitätInfo
- Publication number
- ATE309372T1 ATE309372T1 AT98926359T AT98926359T ATE309372T1 AT E309372 T1 ATE309372 T1 AT E309372T1 AT 98926359 T AT98926359 T AT 98926359T AT 98926359 T AT98926359 T AT 98926359T AT E309372 T1 ATE309372 T1 AT E309372T1
- Authority
- AT
- Austria
- Prior art keywords
- thioesterases
- plant
- thioesterase
- plants
- engineered
- Prior art date
Links
- 102000005488 Thioesterase Human genes 0.000 title abstract 10
- 108020002982 thioesterase Proteins 0.000 title abstract 10
- 239000000758 substrate Substances 0.000 title abstract 4
- 108700021044 acyl-ACP thioesterase Proteins 0.000 abstract 3
- 230000000694 effects Effects 0.000 abstract 3
- 238000012986 modification Methods 0.000 abstract 3
- 230000004048 modification Effects 0.000 abstract 3
- 108091028043 Nucleic acid sequence Proteins 0.000 abstract 2
- 210000004027 cell Anatomy 0.000 abstract 2
- 108090000790 Enzymes Proteins 0.000 abstract 1
- 102000004190 Enzymes Human genes 0.000 abstract 1
- 210000004899 c-terminal region Anatomy 0.000 abstract 1
- 244000038559 crop plants Species 0.000 abstract 1
- 235000014113 dietary fatty acids Nutrition 0.000 abstract 1
- 229930195729 fatty acid Natural products 0.000 abstract 1
- 239000000194 fatty acid Substances 0.000 abstract 1
- 150000004665 fatty acids Chemical class 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- QIQXTHQIDYTFRH-UHFFFAOYSA-N octadecanoic acid Chemical compound CCCCCCCCCCCCCCCCCC(O)=O QIQXTHQIDYTFRH-UHFFFAOYSA-N 0.000 abstract 1
- 235000015112 vegetable and seed oil Nutrition 0.000 abstract 1
- 235000013311 vegetables Nutrition 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/16—Hydrolases (3) acting on ester bonds (3.1)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
- C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
- C12N15/8242—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits
- C12N15/8243—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits involving biosynthetic or metabolic pathways, i.e. metabolic engineering, e.g. nicotine, caffeine
- C12N15/8247—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits involving biosynthetic or metabolic pathways, i.e. metabolic engineering, e.g. nicotine, caffeine involving modified lipid metabolism, e.g. seed oil composition
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Genetics & Genomics (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Biotechnology (AREA)
- Organic Chemistry (AREA)
- Wood Science & Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- Nutrition Science (AREA)
- Plant Pathology (AREA)
- Biophysics (AREA)
- Physics & Mathematics (AREA)
- Cell Biology (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Medicinal Chemistry (AREA)
- Enzymes And Modification Thereof (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US08/868,458 US6150512A (en) | 1995-05-15 | 1997-06-03 | Engineering plant thioesterases and disclosure of plant thioesterases having novel substrate specificity |
| PCT/US1998/011697 WO1998055633A1 (en) | 1997-06-03 | 1998-06-03 | Engineering plant thioesterases and disclosure of plant thioesterases having novel substrate specificity |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE309372T1 true ATE309372T1 (de) | 2005-11-15 |
Family
ID=25351727
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT98926359T ATE309372T1 (de) | 1997-06-03 | 1998-06-03 | Herstellung von thioesterasen aus pflanzen und offenbarung von thioesterasen aus pflanzen mit neuer substratspezifität |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US6150512A (de) |
| EP (2) | EP1003884B1 (de) |
| JP (1) | JP2002502263A (de) |
| AT (1) | ATE309372T1 (de) |
| BR (1) | BR9810402A (de) |
| CA (1) | CA2291452A1 (de) |
| DE (1) | DE69832283T2 (de) |
| ES (1) | ES2251770T3 (de) |
| WO (1) | WO1998055633A1 (de) |
Families Citing this family (39)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ATE383433T1 (de) * | 1999-08-26 | 2008-01-15 | Calgene Llc | Pflanzen mit veränderten mehrfachungesättigten fettsäuren |
| US7531718B2 (en) * | 1999-08-26 | 2009-05-12 | Monsanto Technology, L.L.C. | Nucleic acid sequences and methods of use for the production of plants with modified polyunsaturated fatty acids |
| US7166771B2 (en) * | 2002-06-21 | 2007-01-23 | Monsanto Technology Llc | Coordinated decrease and increase of gene expression of more than one gene using transgenic constructs |
| US7566813B2 (en) | 2002-03-21 | 2009-07-28 | Monsanto Technology, L.L.C. | Nucleic acid constructs and methods for producing altered seed oil compositions |
| US7601888B2 (en) * | 2002-03-21 | 2009-10-13 | Monsanto Technology L.L.C. | Nucleic acid constructs and methods for producing altered seed oil compositions |
| AR039717A1 (es) * | 2002-06-21 | 2005-03-09 | Monsanto Technology Llc | Construcciones de arn de intrones cadena doble y usos de las mismas |
| CN101213298B (zh) * | 2005-06-30 | 2012-04-18 | 丰田自动车株式会社 | 参与岩芹酸生物合成的新基因和用于生产岩芹酸的方法 |
| CN101421406B (zh) | 2006-02-13 | 2016-08-31 | 孟山都技术有限公司 | 用于产生改变的种子油组成的核酸构建体和方法 |
| CA2893168C (en) | 2006-06-28 | 2017-11-07 | Nucelis Inc. | Fatty acid blends and uses therefor |
| TW200826924A (en) * | 2006-09-08 | 2008-07-01 | Kaneka Corp | Composition containing reduced coenzyme Q10 and lysolecithin |
| MX2010006539A (es) * | 2007-12-11 | 2011-02-23 | Synthetic Genomics Inc | Secrecion de acidos grasos por parte de microorganismos fotosinteticos. |
| US20110023352A1 (en) * | 2007-12-27 | 2011-02-03 | Knuth Mark E | Alkylester fatty acid blends and uses therefor |
| US20100071259A1 (en) * | 2008-08-18 | 2010-03-25 | Ls9, Inc. | Systems and methods for production of mixed fatty esters |
| CN107699545A (zh) | 2008-09-29 | 2018-02-16 | 孟山都技术公司 | 大豆转基因时间mon87705及其检测方法 |
| US8956834B2 (en) * | 2009-06-29 | 2015-02-17 | Synthetic Genomics, Inc. | Acyl-ACP thioesterase genes and uses therefor |
| CN102984935B (zh) | 2009-12-18 | 2016-01-13 | 嘉吉公司 | 产生具有低总饱和脂肪酸含量的油的芸苔属植物 |
| US9695434B2 (en) | 2010-05-25 | 2017-07-04 | Cargill, Incorporated | Brassica plants yielding oils with a low alpha linolenic acid content |
| WO2011150028A2 (en) | 2010-05-25 | 2011-12-01 | Cargill, Incorporated | Brassica plants yielding oils with a low alpha linolenic acid content |
| US8951762B2 (en) | 2011-07-27 | 2015-02-10 | Iowa State University Research Foundation, Inc. | Materials and methods for using an acyl—acyl carrier protein thioesterase and mutants and chimeras thereof in fatty acid synthesis |
| US9399768B2 (en) | 2011-07-27 | 2016-07-26 | Iowa State University Research Foundation, Inc. | Materials and methods for using an acyl-acyl carrier protein thioesterase and mutants and chimeras thereof in fatty acid synthesis |
| US20140357727A1 (en) | 2011-12-20 | 2014-12-04 | Codexis, Inc. | Fatty alcohol forming acyl reductase (far) variants and methods of use |
| US20150133698A1 (en) | 2012-04-20 | 2015-05-14 | Codexis, Inc. | Production of fatty alcohols from engineered microorganisms |
| JP6006553B2 (ja) * | 2012-07-10 | 2016-10-12 | 花王株式会社 | 組換えクラミドモナス属及びそれを用いたラウリン酸高含有油脂の製造方法 |
| US9650655B2 (en) | 2012-07-20 | 2017-05-16 | Codexis, Inc. | Production of fatty alcohols from engineered microorganisms |
| JP5925651B2 (ja) * | 2012-09-20 | 2016-05-25 | 花王株式会社 | チオエステラーゼ改変体を用いた脂質の製造方法 |
| KR20210118216A (ko) | 2012-10-15 | 2021-09-29 | 게노마티카 인코포레이티드 | 특정 길이의 지방 알콜 및 관련 화합물의 생산을 위한 미생물 및 방법 |
| US9512447B2 (en) | 2012-12-14 | 2016-12-06 | Codexis, Inc. | Modified native beta-ketoacyl-ACP synthases and engineered microorganisms |
| BR112015015632A2 (pt) | 2012-12-27 | 2017-12-12 | Kao Corp | acil-acp tioesterase |
| US9567615B2 (en) | 2013-01-29 | 2017-02-14 | Terravia Holdings, Inc. | Variant thioesterases and methods of use |
| US9816079B2 (en) | 2013-01-29 | 2017-11-14 | Terravia Holdings, Inc. | Variant thioesterases and methods of use |
| US9783836B2 (en) | 2013-03-15 | 2017-10-10 | Terravia Holdings, Inc. | Thioesterases and cells for production of tailored oils |
| BR112015020904A2 (pt) | 2013-03-15 | 2017-10-10 | Genomatica Inc | microrganismos e métodos para produção de butadieno e compostos relacionados por assimilação de formiato |
| US9290749B2 (en) | 2013-03-15 | 2016-03-22 | Solazyme, Inc. | Thioesterases and cells for production of tailored oils |
| US11814664B2 (en) | 2013-05-24 | 2023-11-14 | Genomatica, Inc. | Microorganisms and methods for producing (3R)-hydroxybutyl (3R)-hydroxybutyrate |
| WO2015005139A1 (ja) | 2013-07-12 | 2015-01-15 | 花王株式会社 | アシル-acpチオエステラーゼ |
| US20160376600A1 (en) | 2013-11-25 | 2016-12-29 | Genomatica, Inc. | Methods for enhancing microbial production of specific length fatty alcohols in the presence of methanol |
| WO2015194628A1 (ja) * | 2014-06-20 | 2015-12-23 | 花王株式会社 | 脂質の製造方法 |
| US9765368B2 (en) | 2014-07-24 | 2017-09-19 | Terravia Holdings, Inc. | Variant thioesterases and methods of use |
| US10125382B2 (en) | 2014-09-18 | 2018-11-13 | Corbion Biotech, Inc. | Acyl-ACP thioesterases and mutants thereof |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5753475A (en) | 1985-01-17 | 1998-05-19 | Calgene, Inc. | Methods and compositions for regulated transcription and expression of heterologous genes |
| US5512482A (en) * | 1990-04-26 | 1996-04-30 | Calgene, Inc. | Plant thioesterases |
| US5530186A (en) | 1990-12-20 | 1996-06-25 | E. I. Du Pont De Nemours And Company | Nucleotide sequences of soybean acyl-ACP thioesterase genes |
| US5455167A (en) | 1991-05-21 | 1995-10-03 | Calgene Inc. | Medium-chain thioesterases in plants |
| US5850022A (en) * | 1992-10-30 | 1998-12-15 | Calgene, Inc. | Production of myristate in plant cells |
| WO1995013390A2 (en) * | 1993-11-10 | 1995-05-18 | Calgene, Inc. | Plant acyl acp thioesterase sequences |
| US5910630A (en) | 1994-04-06 | 1999-06-08 | Davies; Huw Maelor | Plant lysophosphatidic acid acyltransferases |
| CA2206984A1 (en) * | 1995-05-15 | 1996-11-21 | Calgene, Inc. | Engineering plant thioesterases and disclosure of plant thioesterases having novel substrate specificity |
| EP0795020A4 (de) * | 1995-09-29 | 1999-02-24 | Calgene Inc | Stearoyl - acp thioesterase sequenzen aus pflanzen und methoden zur erhöhung des staratsgehalts pflanzlicher saatöle |
-
1997
- 1997-06-03 US US08/868,458 patent/US6150512A/en not_active Expired - Lifetime
-
1998
- 1998-06-03 AT AT98926359T patent/ATE309372T1/de not_active IP Right Cessation
- 1998-06-03 DE DE69832283T patent/DE69832283T2/de not_active Expired - Lifetime
- 1998-06-03 JP JP50296899A patent/JP2002502263A/ja not_active Ceased
- 1998-06-03 EP EP98926359A patent/EP1003884B1/de not_active Expired - Lifetime
- 1998-06-03 WO PCT/US1998/011697 patent/WO1998055633A1/en not_active Ceased
- 1998-06-03 EP EP05107852A patent/EP1605048A1/de not_active Withdrawn
- 1998-06-03 BR BR9810402-0A patent/BR9810402A/pt not_active Application Discontinuation
- 1998-06-03 ES ES98926359T patent/ES2251770T3/es not_active Expired - Lifetime
- 1998-06-03 CA CA002291452A patent/CA2291452A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| EP1003884B1 (de) | 2005-11-09 |
| BR9810402A (pt) | 2000-08-29 |
| DE69832283D1 (de) | 2005-12-15 |
| WO1998055633A1 (en) | 1998-12-10 |
| EP1605048A1 (de) | 2005-12-14 |
| DE69832283T2 (de) | 2006-08-10 |
| EP1003884A1 (de) | 2000-05-31 |
| CA2291452A1 (en) | 1998-12-10 |
| ES2251770T3 (es) | 2006-05-01 |
| JP2002502263A (ja) | 2002-01-22 |
| US6150512A (en) | 2000-11-21 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |