ATE309372T1 - Herstellung von thioesterasen aus pflanzen und offenbarung von thioesterasen aus pflanzen mit neuer substratspezifität - Google Patents

Herstellung von thioesterasen aus pflanzen und offenbarung von thioesterasen aus pflanzen mit neuer substratspezifität

Info

Publication number
ATE309372T1
ATE309372T1 AT98926359T AT98926359T ATE309372T1 AT E309372 T1 ATE309372 T1 AT E309372T1 AT 98926359 T AT98926359 T AT 98926359T AT 98926359 T AT98926359 T AT 98926359T AT E309372 T1 ATE309372 T1 AT E309372T1
Authority
AT
Austria
Prior art keywords
thioesterases
plant
thioesterase
plants
engineered
Prior art date
Application number
AT98926359T
Other languages
English (en)
Inventor
Ling Yuan
Original Assignee
Calgene Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Calgene Llc filed Critical Calgene Llc
Application granted granted Critical
Publication of ATE309372T1 publication Critical patent/ATE309372T1/de

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Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14Hydrolases (3)
    • C12N9/16Hydrolases (3) acting on ester bonds (3.1)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8241Phenotypically and genetically modified plants via recombinant DNA technology
    • C12N15/8242Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits
    • C12N15/8243Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits involving biosynthetic or metabolic pathways, i.e. metabolic engineering, e.g. nicotine, caffeine
    • C12N15/8247Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits involving biosynthetic or metabolic pathways, i.e. metabolic engineering, e.g. nicotine, caffeine involving modified lipid metabolism, e.g. seed oil composition

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Zoology (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • Wood Science & Technology (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Nutrition Science (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Medicinal Chemistry (AREA)
  • Cell Biology (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
AT98926359T 1997-06-03 1998-06-03 Herstellung von thioesterasen aus pflanzen und offenbarung von thioesterasen aus pflanzen mit neuer substratspezifität ATE309372T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/868,458 US6150512A (en) 1995-05-15 1997-06-03 Engineering plant thioesterases and disclosure of plant thioesterases having novel substrate specificity
PCT/US1998/011697 WO1998055633A1 (en) 1997-06-03 1998-06-03 Engineering plant thioesterases and disclosure of plant thioesterases having novel substrate specificity

Publications (1)

Publication Number Publication Date
ATE309372T1 true ATE309372T1 (de) 2005-11-15

Family

ID=25351727

Family Applications (1)

Application Number Title Priority Date Filing Date
AT98926359T ATE309372T1 (de) 1997-06-03 1998-06-03 Herstellung von thioesterasen aus pflanzen und offenbarung von thioesterasen aus pflanzen mit neuer substratspezifität

Country Status (9)

Country Link
US (1) US6150512A (de)
EP (2) EP1605048A1 (de)
JP (1) JP2002502263A (de)
AT (1) ATE309372T1 (de)
BR (1) BR9810402A (de)
CA (1) CA2291452A1 (de)
DE (1) DE69832283T2 (de)
ES (1) ES2251770T3 (de)
WO (1) WO1998055633A1 (de)

Families Citing this family (39)

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WO2001014538A2 (en) * 1999-08-26 2001-03-01 Calgene Llc Plants with modified polyunsaturated fatty acids
US7531718B2 (en) * 1999-08-26 2009-05-12 Monsanto Technology, L.L.C. Nucleic acid sequences and methods of use for the production of plants with modified polyunsaturated fatty acids
US7166771B2 (en) * 2002-06-21 2007-01-23 Monsanto Technology Llc Coordinated decrease and increase of gene expression of more than one gene using transgenic constructs
US7566813B2 (en) 2002-03-21 2009-07-28 Monsanto Technology, L.L.C. Nucleic acid constructs and methods for producing altered seed oil compositions
BR0308614A (pt) * 2002-03-21 2005-02-09 Monsanto Technology Llc Construções de ácidos nucléicos e processos para a produção de composições oleosas de sementes alteradas
WO2004001000A2 (en) * 2002-06-21 2003-12-31 Monsanto Technology Llc Intron double stranded rna constructs and uses thereof
CA2614062C (en) * 2005-06-30 2011-11-15 Toyota Jidosha Kabushiki Kaisha Novel genes involved in petroselinic acid biosynthesis and method for producing petroselinic acid
CN101421406B (zh) 2006-02-13 2016-08-31 孟山都技术有限公司 用于产生改变的种子油组成的核酸构建体和方法
CA2893168C (en) 2006-06-28 2017-11-07 Nucelis Inc. Fatty acid blends and uses therefor
CA2662607A1 (en) * 2006-09-08 2008-03-13 Kaneka Corporation Composition comprising reduced coenzyme q10 and lysolecithin
BRPI0821508B1 (pt) * 2007-12-11 2018-12-26 Synthetic Genomics Inc cultura celular compreendendo uma cianobactéria recombinante da espécie synechococcus elongatus e método para converter carbono inorgânico em ácidos graxos.
JP2011508047A (ja) * 2007-12-27 2011-03-10 サイバス,エルエルシー アルキルエステル脂肪酸配合物およびその用途
US20100071259A1 (en) * 2008-08-18 2010-03-25 Ls9, Inc. Systems and methods for production of mixed fatty esters
JP5767585B2 (ja) 2008-09-29 2015-08-19 モンサント テクノロジー エルエルシー 大豆遺伝子組換え事象mon87705およびその検出方法
US8956834B2 (en) * 2009-06-29 2015-02-17 Synthetic Genomics, Inc. Acyl-ACP thioesterase genes and uses therefor
EP2521437A4 (de) 2009-12-18 2013-05-01 Cargill Inc Gewinnung von öl aus kohlpflanzen mit geringem gesamtgehalt an gesättigten fettsäuren
US9695434B2 (en) 2010-05-25 2017-07-04 Cargill, Incorporated Brassica plants yielding oils with a low alpha linolenic acid content
RU2012156277A (ru) 2010-05-25 2014-06-27 Карджилл, Инкорпорейтед Растения brassica, дающие масла с низким содержанием альфа-линоленовой кислоты
US9399768B2 (en) 2011-07-27 2016-07-26 Iowa State University Research Foundation, Inc. Materials and methods for using an acyl-acyl carrier protein thioesterase and mutants and chimeras thereof in fatty acid synthesis
US8951762B2 (en) 2011-07-27 2015-02-10 Iowa State University Research Foundation, Inc. Materials and methods for using an acyl—acyl carrier protein thioesterase and mutants and chimeras thereof in fatty acid synthesis
EP2794884A4 (de) 2011-12-20 2015-09-16 Codexis Inc Fettalkoholproduzierende acylreduktase (varianten) und verwendungsverfahren dafür
WO2013159055A1 (en) 2012-04-20 2013-10-24 Codexis, Inc. Production of fatty alcohols from engineered microorganisms
JP6006553B2 (ja) * 2012-07-10 2016-10-12 花王株式会社 組換えクラミドモナス属及びそれを用いたラウリン酸高含有油脂の製造方法
WO2014015278A1 (en) 2012-07-20 2014-01-23 Codexis, Inc. Production of fatty alcohols from engineered microorganisms
JP5925651B2 (ja) 2012-09-20 2016-05-25 花王株式会社 チオエステラーゼ改変体を用いた脂質の製造方法
CA2888197C (en) 2012-10-15 2023-03-07 Genomatica, Inc. Microorganisms and methods for production of specific length fatty alcohols and related compounds
US9512447B2 (en) 2012-12-14 2016-12-06 Codexis, Inc. Modified native beta-ketoacyl-ACP synthases and engineered microorganisms
AU2013367325B2 (en) 2012-12-27 2019-12-19 Kao Corporation Acyl-ACP thioesterase
US9567615B2 (en) * 2013-01-29 2017-02-14 Terravia Holdings, Inc. Variant thioesterases and methods of use
US9816079B2 (en) 2013-01-29 2017-11-14 Terravia Holdings, Inc. Variant thioesterases and methods of use
EP2971021A4 (de) 2013-03-15 2016-12-21 Genomatica Inc Mikroorganismen und verfahren zur herstellung von butadien und verwandten verbindungen mittels formatassimilation
US9290749B2 (en) 2013-03-15 2016-03-22 Solazyme, Inc. Thioesterases and cells for production of tailored oils
US9783836B2 (en) 2013-03-15 2017-10-10 Terravia Holdings, Inc. Thioesterases and cells for production of tailored oils
US11814664B2 (en) 2013-05-24 2023-11-14 Genomatica, Inc. Microorganisms and methods for producing (3R)-hydroxybutyl (3R)-hydroxybutyrate
BR112016000553A2 (pt) 2013-07-12 2018-05-29 Kao Corporation acil-acp tioesterase
US20160376600A1 (en) 2013-11-25 2016-12-29 Genomatica, Inc. Methods for enhancing microbial production of specific length fatty alcohols in the presence of methanol
WO2015194628A1 (ja) * 2014-06-20 2015-12-23 花王株式会社 脂質の製造方法
ES2772123T3 (es) * 2014-07-24 2020-07-07 Corbion Biotech Inc Variantes de tioesterasas y métodos de uso
EP3194582A2 (de) 2014-09-18 2017-07-26 TerraVia Holdings, Inc. Acyl-acp-thioesterasen und mutanten davon

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5753475A (en) 1985-01-17 1998-05-19 Calgene, Inc. Methods and compositions for regulated transcription and expression of heterologous genes
US5512482A (en) * 1990-04-26 1996-04-30 Calgene, Inc. Plant thioesterases
DK0563191T4 (da) 1990-12-20 2000-07-17 Du Pont Nucleotidsekvenser af sojabønne-acyl-ACP-thioesterase-gener
US5455167A (en) 1991-05-21 1995-10-03 Calgene Inc. Medium-chain thioesterases in plants
US5850022A (en) * 1992-10-30 1998-12-15 Calgene, Inc. Production of myristate in plant cells
CA2176137A1 (en) * 1993-11-10 1995-05-18 Alois Toni Voelker Plant acyl acp thioesterase sequences
US5910630A (en) 1994-04-06 1999-06-08 Davies; Huw Maelor Plant lysophosphatidic acid acyltransferases
WO1996036719A1 (en) * 1995-05-15 1996-11-21 Calgene, Inc. Engineering plant thioesterases and disclosure of plant thioesterases having novel substrate specificity
CA2205657A1 (en) * 1995-09-29 1997-04-03 Calgene, Inc. Plant stearoyl-acp thioesterase sequences and methods to increase stearate content in plant seed oils

Also Published As

Publication number Publication date
JP2002502263A (ja) 2002-01-22
DE69832283D1 (de) 2005-12-15
US6150512A (en) 2000-11-21
ES2251770T3 (es) 2006-05-01
EP1003884B1 (de) 2005-11-09
DE69832283T2 (de) 2006-08-10
CA2291452A1 (en) 1998-12-10
EP1003884A1 (de) 2000-05-31
BR9810402A (pt) 2000-08-29
WO1998055633A1 (en) 1998-12-10
EP1605048A1 (de) 2005-12-14

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