ATE309372T1 - Herstellung von thioesterasen aus pflanzen und offenbarung von thioesterasen aus pflanzen mit neuer substratspezifität - Google Patents
Herstellung von thioesterasen aus pflanzen und offenbarung von thioesterasen aus pflanzen mit neuer substratspezifitätInfo
- Publication number
- ATE309372T1 ATE309372T1 AT98926359T AT98926359T ATE309372T1 AT E309372 T1 ATE309372 T1 AT E309372T1 AT 98926359 T AT98926359 T AT 98926359T AT 98926359 T AT98926359 T AT 98926359T AT E309372 T1 ATE309372 T1 AT E309372T1
- Authority
- AT
- Austria
- Prior art keywords
- thioesterases
- plant
- thioesterase
- plants
- engineered
- Prior art date
Links
- 102000005488 Thioesterase Human genes 0.000 title abstract 10
- 108020002982 thioesterase Proteins 0.000 title abstract 10
- 239000000758 substrate Substances 0.000 title abstract 4
- 108700021044 acyl-ACP thioesterase Proteins 0.000 abstract 3
- 230000000694 effects Effects 0.000 abstract 3
- 238000012986 modification Methods 0.000 abstract 3
- 230000004048 modification Effects 0.000 abstract 3
- 108091028043 Nucleic acid sequence Proteins 0.000 abstract 2
- 210000004027 cell Anatomy 0.000 abstract 2
- 108090000790 Enzymes Proteins 0.000 abstract 1
- 102000004190 Enzymes Human genes 0.000 abstract 1
- 210000004899 c-terminal region Anatomy 0.000 abstract 1
- 244000038559 crop plants Species 0.000 abstract 1
- 235000014113 dietary fatty acids Nutrition 0.000 abstract 1
- 229930195729 fatty acid Natural products 0.000 abstract 1
- 239000000194 fatty acid Substances 0.000 abstract 1
- 150000004665 fatty acids Chemical class 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- QIQXTHQIDYTFRH-UHFFFAOYSA-N octadecanoic acid Chemical compound CCCCCCCCCCCCCCCCCC(O)=O QIQXTHQIDYTFRH-UHFFFAOYSA-N 0.000 abstract 1
- 235000015112 vegetable and seed oil Nutrition 0.000 abstract 1
- 235000013311 vegetables Nutrition 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/16—Hydrolases (3) acting on ester bonds (3.1)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
- C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
- C12N15/8242—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits
- C12N15/8243—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits involving biosynthetic or metabolic pathways, i.e. metabolic engineering, e.g. nicotine, caffeine
- C12N15/8247—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits involving biosynthetic or metabolic pathways, i.e. metabolic engineering, e.g. nicotine, caffeine involving modified lipid metabolism, e.g. seed oil composition
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Genetics & Genomics (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Zoology (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biotechnology (AREA)
- Wood Science & Technology (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- General Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Nutrition Science (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Medicinal Chemistry (AREA)
- Cell Biology (AREA)
- Physics & Mathematics (AREA)
- Biophysics (AREA)
- Plant Pathology (AREA)
- Enzymes And Modification Thereof (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US08/868,458 US6150512A (en) | 1995-05-15 | 1997-06-03 | Engineering plant thioesterases and disclosure of plant thioesterases having novel substrate specificity |
| PCT/US1998/011697 WO1998055633A1 (en) | 1997-06-03 | 1998-06-03 | Engineering plant thioesterases and disclosure of plant thioesterases having novel substrate specificity |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE309372T1 true ATE309372T1 (de) | 2005-11-15 |
Family
ID=25351727
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT98926359T ATE309372T1 (de) | 1997-06-03 | 1998-06-03 | Herstellung von thioesterasen aus pflanzen und offenbarung von thioesterasen aus pflanzen mit neuer substratspezifität |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US6150512A (de) |
| EP (2) | EP1605048A1 (de) |
| JP (1) | JP2002502263A (de) |
| AT (1) | ATE309372T1 (de) |
| BR (1) | BR9810402A (de) |
| CA (1) | CA2291452A1 (de) |
| DE (1) | DE69832283T2 (de) |
| ES (1) | ES2251770T3 (de) |
| WO (1) | WO1998055633A1 (de) |
Families Citing this family (39)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2001014538A2 (en) * | 1999-08-26 | 2001-03-01 | Calgene Llc | Plants with modified polyunsaturated fatty acids |
| US7531718B2 (en) * | 1999-08-26 | 2009-05-12 | Monsanto Technology, L.L.C. | Nucleic acid sequences and methods of use for the production of plants with modified polyunsaturated fatty acids |
| US7166771B2 (en) * | 2002-06-21 | 2007-01-23 | Monsanto Technology Llc | Coordinated decrease and increase of gene expression of more than one gene using transgenic constructs |
| US7566813B2 (en) | 2002-03-21 | 2009-07-28 | Monsanto Technology, L.L.C. | Nucleic acid constructs and methods for producing altered seed oil compositions |
| BR0308614A (pt) * | 2002-03-21 | 2005-02-09 | Monsanto Technology Llc | Construções de ácidos nucléicos e processos para a produção de composições oleosas de sementes alteradas |
| WO2004001000A2 (en) * | 2002-06-21 | 2003-12-31 | Monsanto Technology Llc | Intron double stranded rna constructs and uses thereof |
| CA2614062C (en) * | 2005-06-30 | 2011-11-15 | Toyota Jidosha Kabushiki Kaisha | Novel genes involved in petroselinic acid biosynthesis and method for producing petroselinic acid |
| CN101421406B (zh) | 2006-02-13 | 2016-08-31 | 孟山都技术有限公司 | 用于产生改变的种子油组成的核酸构建体和方法 |
| CA2893168C (en) | 2006-06-28 | 2017-11-07 | Nucelis Inc. | Fatty acid blends and uses therefor |
| CA2662607A1 (en) * | 2006-09-08 | 2008-03-13 | Kaneka Corporation | Composition comprising reduced coenzyme q10 and lysolecithin |
| BRPI0821508B1 (pt) * | 2007-12-11 | 2018-12-26 | Synthetic Genomics Inc | cultura celular compreendendo uma cianobactéria recombinante da espécie synechococcus elongatus e método para converter carbono inorgânico em ácidos graxos. |
| JP2011508047A (ja) * | 2007-12-27 | 2011-03-10 | サイバス,エルエルシー | アルキルエステル脂肪酸配合物およびその用途 |
| US20100071259A1 (en) * | 2008-08-18 | 2010-03-25 | Ls9, Inc. | Systems and methods for production of mixed fatty esters |
| JP5767585B2 (ja) | 2008-09-29 | 2015-08-19 | モンサント テクノロジー エルエルシー | 大豆遺伝子組換え事象mon87705およびその検出方法 |
| US8956834B2 (en) * | 2009-06-29 | 2015-02-17 | Synthetic Genomics, Inc. | Acyl-ACP thioesterase genes and uses therefor |
| EP2521437A4 (de) | 2009-12-18 | 2013-05-01 | Cargill Inc | Gewinnung von öl aus kohlpflanzen mit geringem gesamtgehalt an gesättigten fettsäuren |
| US9695434B2 (en) | 2010-05-25 | 2017-07-04 | Cargill, Incorporated | Brassica plants yielding oils with a low alpha linolenic acid content |
| RU2012156277A (ru) | 2010-05-25 | 2014-06-27 | Карджилл, Инкорпорейтед | Растения brassica, дающие масла с низким содержанием альфа-линоленовой кислоты |
| US9399768B2 (en) | 2011-07-27 | 2016-07-26 | Iowa State University Research Foundation, Inc. | Materials and methods for using an acyl-acyl carrier protein thioesterase and mutants and chimeras thereof in fatty acid synthesis |
| US8951762B2 (en) | 2011-07-27 | 2015-02-10 | Iowa State University Research Foundation, Inc. | Materials and methods for using an acyl—acyl carrier protein thioesterase and mutants and chimeras thereof in fatty acid synthesis |
| EP2794884A4 (de) | 2011-12-20 | 2015-09-16 | Codexis Inc | Fettalkoholproduzierende acylreduktase (varianten) und verwendungsverfahren dafür |
| WO2013159055A1 (en) | 2012-04-20 | 2013-10-24 | Codexis, Inc. | Production of fatty alcohols from engineered microorganisms |
| JP6006553B2 (ja) * | 2012-07-10 | 2016-10-12 | 花王株式会社 | 組換えクラミドモナス属及びそれを用いたラウリン酸高含有油脂の製造方法 |
| WO2014015278A1 (en) | 2012-07-20 | 2014-01-23 | Codexis, Inc. | Production of fatty alcohols from engineered microorganisms |
| JP5925651B2 (ja) | 2012-09-20 | 2016-05-25 | 花王株式会社 | チオエステラーゼ改変体を用いた脂質の製造方法 |
| CA2888197C (en) | 2012-10-15 | 2023-03-07 | Genomatica, Inc. | Microorganisms and methods for production of specific length fatty alcohols and related compounds |
| US9512447B2 (en) | 2012-12-14 | 2016-12-06 | Codexis, Inc. | Modified native beta-ketoacyl-ACP synthases and engineered microorganisms |
| AU2013367325B2 (en) | 2012-12-27 | 2019-12-19 | Kao Corporation | Acyl-ACP thioesterase |
| US9567615B2 (en) * | 2013-01-29 | 2017-02-14 | Terravia Holdings, Inc. | Variant thioesterases and methods of use |
| US9816079B2 (en) | 2013-01-29 | 2017-11-14 | Terravia Holdings, Inc. | Variant thioesterases and methods of use |
| EP2971021A4 (de) | 2013-03-15 | 2016-12-21 | Genomatica Inc | Mikroorganismen und verfahren zur herstellung von butadien und verwandten verbindungen mittels formatassimilation |
| US9290749B2 (en) | 2013-03-15 | 2016-03-22 | Solazyme, Inc. | Thioesterases and cells for production of tailored oils |
| US9783836B2 (en) | 2013-03-15 | 2017-10-10 | Terravia Holdings, Inc. | Thioesterases and cells for production of tailored oils |
| US11814664B2 (en) | 2013-05-24 | 2023-11-14 | Genomatica, Inc. | Microorganisms and methods for producing (3R)-hydroxybutyl (3R)-hydroxybutyrate |
| BR112016000553A2 (pt) | 2013-07-12 | 2018-05-29 | Kao Corporation | acil-acp tioesterase |
| US20160376600A1 (en) | 2013-11-25 | 2016-12-29 | Genomatica, Inc. | Methods for enhancing microbial production of specific length fatty alcohols in the presence of methanol |
| WO2015194628A1 (ja) * | 2014-06-20 | 2015-12-23 | 花王株式会社 | 脂質の製造方法 |
| ES2772123T3 (es) * | 2014-07-24 | 2020-07-07 | Corbion Biotech Inc | Variantes de tioesterasas y métodos de uso |
| EP3194582A2 (de) | 2014-09-18 | 2017-07-26 | TerraVia Holdings, Inc. | Acyl-acp-thioesterasen und mutanten davon |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5753475A (en) | 1985-01-17 | 1998-05-19 | Calgene, Inc. | Methods and compositions for regulated transcription and expression of heterologous genes |
| US5512482A (en) * | 1990-04-26 | 1996-04-30 | Calgene, Inc. | Plant thioesterases |
| DK0563191T4 (da) | 1990-12-20 | 2000-07-17 | Du Pont | Nucleotidsekvenser af sojabønne-acyl-ACP-thioesterase-gener |
| US5455167A (en) | 1991-05-21 | 1995-10-03 | Calgene Inc. | Medium-chain thioesterases in plants |
| US5850022A (en) * | 1992-10-30 | 1998-12-15 | Calgene, Inc. | Production of myristate in plant cells |
| CA2176137A1 (en) * | 1993-11-10 | 1995-05-18 | Alois Toni Voelker | Plant acyl acp thioesterase sequences |
| US5910630A (en) | 1994-04-06 | 1999-06-08 | Davies; Huw Maelor | Plant lysophosphatidic acid acyltransferases |
| WO1996036719A1 (en) * | 1995-05-15 | 1996-11-21 | Calgene, Inc. | Engineering plant thioesterases and disclosure of plant thioesterases having novel substrate specificity |
| CA2205657A1 (en) * | 1995-09-29 | 1997-04-03 | Calgene, Inc. | Plant stearoyl-acp thioesterase sequences and methods to increase stearate content in plant seed oils |
-
1997
- 1997-06-03 US US08/868,458 patent/US6150512A/en not_active Expired - Lifetime
-
1998
- 1998-06-03 CA CA002291452A patent/CA2291452A1/en not_active Abandoned
- 1998-06-03 DE DE69832283T patent/DE69832283T2/de not_active Expired - Lifetime
- 1998-06-03 EP EP05107852A patent/EP1605048A1/de not_active Withdrawn
- 1998-06-03 ES ES98926359T patent/ES2251770T3/es not_active Expired - Lifetime
- 1998-06-03 EP EP98926359A patent/EP1003884B1/de not_active Expired - Lifetime
- 1998-06-03 BR BR9810402-0A patent/BR9810402A/pt not_active Application Discontinuation
- 1998-06-03 WO PCT/US1998/011697 patent/WO1998055633A1/en not_active Ceased
- 1998-06-03 JP JP50296899A patent/JP2002502263A/ja not_active Ceased
- 1998-06-03 AT AT98926359T patent/ATE309372T1/de not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| JP2002502263A (ja) | 2002-01-22 |
| DE69832283D1 (de) | 2005-12-15 |
| US6150512A (en) | 2000-11-21 |
| ES2251770T3 (es) | 2006-05-01 |
| EP1003884B1 (de) | 2005-11-09 |
| DE69832283T2 (de) | 2006-08-10 |
| CA2291452A1 (en) | 1998-12-10 |
| EP1003884A1 (de) | 2000-05-31 |
| BR9810402A (pt) | 2000-08-29 |
| WO1998055633A1 (en) | 1998-12-10 |
| EP1605048A1 (de) | 2005-12-14 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |