ATE309804T1 - Foerderung der wundheilung durch chemisch modifizierte tetracycline - Google Patents

Foerderung der wundheilung durch chemisch modifizierte tetracycline

Info

Publication number
ATE309804T1
ATE309804T1 AT97935248T AT97935248T ATE309804T1 AT E309804 T1 ATE309804 T1 AT E309804T1 AT 97935248 T AT97935248 T AT 97935248T AT 97935248 T AT97935248 T AT 97935248T AT E309804 T1 ATE309804 T1 AT E309804T1
Authority
AT
Austria
Prior art keywords
activity
wound healing
capacity
epithelialized tissue
healing
Prior art date
Application number
AT97935248T
Other languages
English (en)
Inventor
Nungavaram S Ramamurthy
Lorne M Golub
Thomas F Mcnamara
Original Assignee
Univ New York State Res Found
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ New York State Res Found filed Critical Univ New York State Res Found
Application granted granted Critical
Publication of ATE309804T1 publication Critical patent/ATE309804T1/de

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/65Tetracyclines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L15/00Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
    • A61L15/16Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
    • A61L15/42Use of materials characterised by their function or physical properties
    • A61L15/44Medicaments
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/02Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/404Biocides, antimicrobial agents, antiseptic agents
    • A61L2300/406Antibiotics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/41Anti-inflammatory agents, e.g. NSAIDs
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/412Tissue-regenerating or healing or proliferative agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • Materials Engineering (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Dermatology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
AT97935248T 1996-08-01 1997-08-01 Foerderung der wundheilung durch chemisch modifizierte tetracycline ATE309804T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/691,135 US5827840A (en) 1996-08-01 1996-08-01 Promotion of wound healing by chemically-modified tetracyclines
PCT/US1997/013534 WO1998005340A1 (en) 1996-08-01 1997-08-01 Promotion of wound healing by chemically-modified tetracyclines

Publications (1)

Publication Number Publication Date
ATE309804T1 true ATE309804T1 (de) 2005-12-15

Family

ID=24775298

Family Applications (1)

Application Number Title Priority Date Filing Date
AT97935248T ATE309804T1 (de) 1996-08-01 1997-08-01 Foerderung der wundheilung durch chemisch modifizierte tetracycline

Country Status (11)

Country Link
US (1) US5827840A (de)
EP (1) EP0923378B1 (de)
JP (1) JP2000516214A (de)
KR (1) KR100494206B1 (de)
AT (1) ATE309804T1 (de)
AU (1) AU3823497A (de)
CA (1) CA2261805C (de)
DE (1) DE69734661T2 (de)
DK (1) DK0923378T3 (de)
ES (1) ES2255107T3 (de)
WO (1) WO1998005340A1 (de)

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MXPA01012169A (es) 1999-05-27 2002-06-21 Euro Celtique Sa Preparaciones para la aplicacion de agentes anti-infecciosos y/o anti-lamatorios para partes externas o internas del cuerpo humano o animal en la remodelacion funcional y cosmetica y tratamientos para reparacion de tejidos.
EP1829546A1 (de) * 1999-09-14 2007-09-05 Mucosal Therapeutics LLC Formulierungen zur Behandlung oder Vorbeugung von Mucositis
EP1212050B1 (de) * 1999-09-14 2006-12-06 Mucosal Therapeutics LLC Zusammensetzungen, welche tetracycline enthalten, zur behandlung oder verhinderung von mukositis
US6946118B1 (en) * 1999-09-14 2005-09-20 Orapharma, Inc. Formulations for treating or preventing mucositis
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EP2311440A1 (de) * 2001-04-05 2011-04-20 Collagenex Pharmaceuticals, Inc. Gesteuerte Freigabe von Tetracyclinverbindungen und Tetracyclinderivaten
EP1383508B1 (de) * 2001-04-05 2006-06-21 Collagenex Pharmaceuticals, Inc. Doxycyclin zur behandlung von akne
US7211267B2 (en) 2001-04-05 2007-05-01 Collagenex Pharmaceuticals, Inc. Methods of treating acne
EP2327409A1 (de) 2001-07-13 2011-06-01 Paratek Pharmaceuticals, Inc. Tetracycline Verbindung mit therapeutischer Wirkung
US20060194773A1 (en) * 2001-07-13 2006-08-31 Paratek Pharmaceuticals, Inc. Tetracyline compounds having target therapeutic activities
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EP1684768A4 (de) * 2003-11-06 2007-06-06 Univ New York State Res Found Verfahren zur behandlung von ekzem
JP5010284B2 (ja) * 2004-01-15 2012-08-29 パラテック ファーマシューティカルズ インコーポレイテッド テトラサイクリン化合物の芳香族a環誘導体
EP1805134B1 (de) 2004-10-25 2012-06-20 Paratek Pharmaceuticals, Inc. 4-aminotetracycline und verfahren zu ihrer verwendung
EP2033950A1 (de) 2004-10-25 2009-03-11 Paratek Pharmaceuticals, Inc. Substituierte Tetracyclin-Verbindungen
US20060252731A1 (en) * 2005-05-06 2006-11-09 Pfeiffer David F Methods of treating recurrent aphthous stomatitis
US20070093455A1 (en) * 2005-07-21 2007-04-26 Paul Abato 10-substituted tetracyclines and methods of use thereof
CA2892739A1 (en) 2006-12-21 2008-07-03 Paratek Pharmaceuticals, Inc. Substituted tetracycline compounds for treatment of inflammatory skin disorders
WO2008079339A2 (en) 2006-12-21 2008-07-03 Paratek Pharmaceuticals, Inc. Tetracycline derivatives for the treatment of bacterial, viral and parasitic infections
EP2216323A3 (de) * 2007-04-27 2010-12-29 Paratek Pharmaceuticals, Inc. Verfahren zur Synthetisierung und Reinigung von Aminoalkyl-Tetracyclinverbindungen
EP2176216B1 (de) * 2007-07-06 2012-04-25 Paratek Pharmaceuticals, Inc. Verfahren zur synthese von 9-substituiertem minocyclin
TWI680117B (zh) 2008-05-19 2019-12-21 派洛泰克藥物股份有限公司 四環素化合物之甲苯磺酸鹽及同素異形體
KR101746795B1 (ko) 2008-08-08 2017-06-13 테트라페이즈 파마슈티컬스, 인코포레이티드 C7-플루오로 치환된 테트라시클린 화합물
WO2010129057A2 (en) 2009-05-08 2010-11-11 Tetraphase Pharmaceuticals, Inc. Tetracycline compounds
NO2470500T3 (de) 2009-08-28 2018-03-03
DK2552890T3 (en) 2010-03-31 2017-04-03 Tetraphase Pharmaceuticals Inc POLYCYCLIC TETRACYCLINE COMPOUNDS
CA2883238C (en) 2012-08-31 2021-11-23 Tetraphase Pharmaceuticals, Inc. Tetracycline compounds
CN104307031B (zh) * 2014-11-10 2015-12-30 刘维峰 一种皮肤外用修复材料的制备方法及用途
HUE066360T2 (hu) 2016-10-19 2024-07-28 Tetraphase Pharmaceuticals Inc Eravaciklin kristályformái
US12570604B2 (en) 2018-11-09 2026-03-10 Tetraphase Pharmaceuticals, Inc. Polymorphic forms of a tetracycline compound and uses thereof

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Also Published As

Publication number Publication date
EP0923378A1 (de) 1999-06-23
CA2261805C (en) 2008-11-04
DK0923378T3 (da) 2006-04-03
EP0923378B1 (de) 2005-11-16
EP0923378A4 (de) 2000-11-15
WO1998005340A1 (en) 1998-02-12
KR20000029753A (ko) 2000-05-25
JP2000516214A (ja) 2000-12-05
AU3823497A (en) 1998-02-25
DE69734661D1 (de) 2005-12-22
ES2255107T3 (es) 2006-06-16
US5827840A (en) 1998-10-27
KR100494206B1 (ko) 2005-06-13
DE69734661T2 (de) 2006-08-10
CA2261805A1 (en) 1998-02-12

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