DK0923378T3 - Fremme af sårheling ved kemisk modificerede tetracykliner - Google Patents
Fremme af sårheling ved kemisk modificerede tetracyklinerInfo
- Publication number
- DK0923378T3 DK0923378T3 DK97935248T DK97935248T DK0923378T3 DK 0923378 T3 DK0923378 T3 DK 0923378T3 DK 97935248 T DK97935248 T DK 97935248T DK 97935248 T DK97935248 T DK 97935248T DK 0923378 T3 DK0923378 T3 DK 0923378T3
- Authority
- DK
- Denmark
- Prior art keywords
- activity
- wound healing
- capacity
- epithelialized tissue
- healing
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
- A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
- A61L15/42—Use of materials characterised by their function or physical properties
- A61L15/44—Medicaments
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/65—Tetracyclines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
- A61L2300/404—Biocides, antimicrobial agents, antiseptic agents
- A61L2300/406—Antibiotics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
- A61L2300/41—Anti-inflammatory agents, e.g. NSAIDs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
- A61L2300/412—Tissue-regenerating or healing or proliferative agents
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Hematology (AREA)
- Materials Engineering (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Dermatology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US08/691,135 US5827840A (en) | 1996-08-01 | 1996-08-01 | Promotion of wound healing by chemically-modified tetracyclines |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK0923378T3 true DK0923378T3 (da) | 2006-04-03 |
Family
ID=24775298
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK97935248T DK0923378T3 (da) | 1996-08-01 | 1997-08-01 | Fremme af sårheling ved kemisk modificerede tetracykliner |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US5827840A (da) |
| EP (1) | EP0923378B1 (da) |
| JP (1) | JP2000516214A (da) |
| KR (1) | KR100494206B1 (da) |
| AT (1) | ATE309804T1 (da) |
| AU (1) | AU3823497A (da) |
| CA (1) | CA2261805C (da) |
| DE (1) | DE69734661T2 (da) |
| DK (1) | DK0923378T3 (da) |
| ES (1) | ES2255107T3 (da) |
| WO (1) | WO1998005340A1 (da) |
Families Citing this family (45)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6015804A (en) * | 1998-09-11 | 2000-01-18 | The Research Foundation Of State University Of New York | Method of using tetracycline compounds to enhance interleukin-10 production |
| JP4937453B2 (ja) | 1999-05-27 | 2012-05-23 | ユーロ−セルティック エス. ア. | 抗感染剤および/または抗炎症剤を適用するための製剤 |
| US7300667B1 (en) | 1999-05-27 | 2007-11-27 | Euro-Celtique, S.A. | Preparations for the application of anti-inflammatory, especially antiseptic agents and/or agents promoting the healing of wounds, to the lower respiratory tract |
| EP1829546A1 (en) * | 1999-09-14 | 2007-09-05 | Mucosal Therapeutics LLC | Formulations containing tetracyclines for treating or preventing mucositis |
| DK1212050T3 (da) * | 1999-09-14 | 2007-02-26 | Mucosal Therapeutics Llc | Formuleringer indeholdende tetracycliner til behandling eller forebyggelse af mucositis |
| US6946118B1 (en) | 1999-09-14 | 2005-09-20 | Orapharma, Inc. | Formulations for treating or preventing mucositis |
| KR20030024683A (ko) * | 2000-06-02 | 2003-03-26 | 유 리우 | 항진균제로서 비-항균성 테트라사이클린 |
| AU2002256092C1 (en) * | 2001-04-05 | 2009-10-15 | Collagenex Pharmaceuticals, Inc. | Controlled delivery of tetracycline compounds and tetracycline derivatives |
| DE60212613T2 (de) * | 2001-04-05 | 2007-05-24 | Collagenex Pharmaceuticals, Inc. | Doxycyclin zur behandlung von akne |
| US7211267B2 (en) * | 2001-04-05 | 2007-05-01 | Collagenex Pharmaceuticals, Inc. | Methods of treating acne |
| JP2004537544A (ja) | 2001-07-13 | 2004-12-16 | パラテック ファーマシューティカルズ インコーポレイテッド | 標的治療活性を有するテトラサイクリン化合物 |
| US20060194773A1 (en) * | 2001-07-13 | 2006-08-31 | Paratek Pharmaceuticals, Inc. | Tetracyline compounds having target therapeutic activities |
| WO2003094954A1 (en) * | 2001-09-25 | 2003-11-20 | Quick Med Technologies, Inc. | Composition and method for minimizing or avoiding adverse effects of vesicants |
| WO2003053447A1 (en) * | 2001-12-20 | 2003-07-03 | Hanauske-Abel Hartmut M | Treatment for averting or delaying premature delivery |
| ES2551708T3 (es) | 2002-01-08 | 2015-11-23 | Paratek Pharmaceuticals, Inc. | Compuestos de 4-desdimetilamino tetraciclina |
| EP1482926A4 (en) | 2002-03-08 | 2006-04-12 | Paratek Pharm Innc | AMINO METHYL SUBSTITUTED TETRACYCLINE COMPOUNDS |
| WO2003079984A2 (en) | 2002-03-21 | 2003-10-02 | Paratek Pharmaceuticals, Inc. | Substituted tetracycline compounds |
| US8192749B2 (en) | 2003-04-16 | 2012-06-05 | Galderma Laboratories Inc. | Methods of simultaneously treating ocular rosacea and acne rosacea |
| CA2476792A1 (en) * | 2002-04-16 | 2003-10-30 | Collagenex Pharmaceuticals, Inc. | Methods of simultaneously treating ocular rosacea and acne rosacea |
| KR20050005466A (ko) * | 2002-05-06 | 2005-01-13 | 콜라제넥스 파마슈티칼스, 인크 | 점막염 및 진균 감염을 동시에 치료하는 방법 |
| NZ538198A (en) * | 2002-07-12 | 2006-11-30 | Univ New York State Res Found | Method for reducing C-reactive protein (CRP) levels by administering a non-antibacterial tetracycline formulation or a low dose of an antibacterial tetracycline formulation |
| EA200900540A1 (ru) | 2002-07-12 | 2009-12-30 | Пэрэтек Фамэсьютикэлс, Инк. | Замещённые соединения тетрациклина, фармацевтическая композиция и способ лечения чувствительного к тетрациклину состояния у субъекта |
| US20080139512A1 (en) * | 2002-09-25 | 2008-06-12 | Quick-Med Technologies, Inc. | Method for minimizing or avoiding adverse effects of vesicants |
| CA2894736C (en) | 2003-04-07 | 2019-07-16 | Supernus Pharmaceuticals, Inc. | Once daily formulations of tetracyclines |
| EP1648859B1 (en) | 2003-07-09 | 2013-02-27 | Paratek Pharmaceuticals, Inc. | Substituted tetracycline compounds |
| JP4738333B2 (ja) | 2003-07-09 | 2011-08-03 | パラテック ファーマシューティカルズ インコーポレイテッド | 9−アミノメチルテトラサイクリン化合物のプロドラッグ |
| WO2005046618A2 (en) * | 2003-11-06 | 2005-05-26 | Research Foundation Of State University Of New York, The | Methods of treating eczema |
| US7786099B2 (en) * | 2004-01-15 | 2010-08-31 | Paratek Pharmaceuticals, Inc. | Aromatic a-ring derivatives of tetracycline compounds |
| EP2269991A3 (en) | 2004-10-25 | 2011-09-21 | Paratek Pharmaceuticals, Inc. | Substituted tetracycline compounds |
| WO2006047671A2 (en) | 2004-10-25 | 2006-05-04 | Paratek Pharmaceuticals, Inc. | 4-aminotetracyclines and methods of use thereof |
| US20060252731A1 (en) * | 2005-05-06 | 2006-11-09 | Pfeiffer David F | Methods of treating recurrent aphthous stomatitis |
| JP2009502809A (ja) * | 2005-07-21 | 2009-01-29 | パラテック ファーマシューティカルズ インコーポレイテッド | 10−置換テトラサイクリンおよびその使用方法 |
| EP2450347B1 (en) | 2006-12-21 | 2015-06-24 | Paratek Pharmaceuticals, Inc. | Tetracycline derivatives for the treatment of bacterial, viral and parasitic infections |
| PT2120963T (pt) * | 2006-12-21 | 2018-12-17 | Paratek Pharm Innc | Compostos tetraciclina substituídos para tratamento de distúrbios inflamatórios da pele |
| JP2010525069A (ja) * | 2007-04-27 | 2010-07-22 | パラテック ファーマシューティカルズ インコーポレイテッド | アミノアルキルテトラサイクリン化合物の合成方法および精製方法 |
| BRPI0813990A2 (pt) * | 2007-07-06 | 2011-09-13 | Paratek Pharmaceuticals, Inc. | métodos para sintetizar compostos de minociclina substituìda |
| TWI680117B (zh) | 2008-05-19 | 2019-12-21 | 派洛泰克藥物股份有限公司 | 四環素化合物之甲苯磺酸鹽及同素異形體 |
| ES2558512T3 (es) | 2008-08-08 | 2016-02-04 | Tetraphase Pharmaceuticals, Inc. | Compuestos de tetraciclina sustituida con C7-fluoro |
| WO2010129057A2 (en) | 2009-05-08 | 2010-11-11 | Tetraphase Pharmaceuticals, Inc. | Tetracycline compounds |
| HUE037852T2 (hu) | 2009-08-28 | 2018-09-28 | Tetraphase Pharmaceuticals Inc | Tetraciklin-vegyületek |
| JP5820462B2 (ja) | 2010-03-31 | 2015-11-24 | テトラフェース ファーマシューティカルズ,インコーポレイテッド | 多環式テトラサイクリン化合物 |
| SMT201900096T1 (it) | 2012-08-31 | 2019-02-28 | Tetraphase Pharmaceuticals Inc | Composti di tetracicline |
| CN104307031B (zh) * | 2014-11-10 | 2015-12-30 | 刘维峰 | 一种皮肤外用修复材料的制备方法及用途 |
| MA46567A (fr) | 2016-10-19 | 2019-08-28 | Tetraphase Pharmaceuticals Inc | Formes cristallines de l'éravacycline |
| WO2020097450A1 (en) | 2018-11-09 | 2020-05-14 | Tetraphase Pharmaceuticals, Inc. | Polymorphic forms of a compound and uses thereof |
Family Cites Families (34)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE1767900U (de) * | 1958-03-27 | 1958-06-04 | Herbert Dipl Ing Fritzsche | Hand- oder taschenleuchte mit blinker. |
| US3823212A (en) * | 1968-11-27 | 1974-07-09 | Freudenberg C Fa | Process for the production of collagen fiber fabrics in the form of felt-like membranes or sponge-like layers |
| US4016877A (en) * | 1976-02-23 | 1977-04-12 | Avicon, Inc. | Fibrous collagen derived web having hemostatic and wound sealing properties |
| US4294241A (en) * | 1977-06-09 | 1981-10-13 | Teruo Miyata | Collagen skin dressing |
| US4130555A (en) * | 1977-09-06 | 1978-12-19 | Nippi Incorporated | Peptide mixtures derived from collagenous material or gelatin |
| US4412947A (en) * | 1979-09-12 | 1983-11-01 | Seton Company | Collagen sponge |
| US4440680A (en) * | 1980-09-24 | 1984-04-03 | Seton Company | Macromolecular biologically active collagen articles |
| DE3037513C2 (de) * | 1980-10-03 | 1983-05-05 | Steffan, Wolfgang, 8425 Neustadt | Kollagene Wundauflage |
| US4578067A (en) * | 1982-04-12 | 1986-03-25 | Alcon (Puerto Rico) Inc. | Hemostatic-adhesive, collagen dressing for severed biological surfaces |
| US4935412A (en) * | 1983-12-29 | 1990-06-19 | The Research Foundation Of State University Of New York | Non-antibacterial tetracycline compositions possessing anti-collagenolytic properties and methods of preparing and using same |
| US4666897A (en) * | 1983-12-29 | 1987-05-19 | Research Foundation Of State University | Inhibition of mammalian collagenolytic enzymes by tetracyclines |
| US4925833A (en) * | 1983-12-29 | 1990-05-15 | The Research Foundation Of State University Of New York | Use of tetracycline to enhance bone protein synthesis and/or treatment of osteoporosis |
| US4704383A (en) * | 1983-12-29 | 1987-11-03 | The Research Foundation Of State University Of New York | Non-antibacterial tetracycline compositions possessing anti-collagenolytic properties and methods of preparing and using same |
| US4837024A (en) * | 1984-02-24 | 1989-06-06 | The Regents Of The University Of California | Compositions, articles and mehtod for improving wound healing |
| US4837285A (en) * | 1984-03-27 | 1989-06-06 | Medimatrix | Collagen matrix beads for soft tissue repair |
| IT1181737B (it) * | 1985-11-26 | 1987-09-30 | Pierfrancesco Morganti | Supproto di collagene biologicamente attivo per uso cosmetico e farmaceutico e metodo per prepararlo |
| US5196196A (en) * | 1986-06-03 | 1993-03-23 | Incyte Pharmaceuticals, Inc. | Use of protease nexin-I in wound dressings |
| US4813942A (en) * | 1987-03-17 | 1989-03-21 | Bioderm, Inc. | Three step wound treatment method and dressing therefor |
| US4969912A (en) * | 1988-02-18 | 1990-11-13 | Kelman Charles D | Human collagen processing and autoimplant use |
| US5110604A (en) * | 1988-06-30 | 1992-05-05 | Collagen Corporation | Processes for producing collagen matrixes and methods of using same |
| US4950483A (en) * | 1988-06-30 | 1990-08-21 | Collagen Corporation | Collagen wound healing matrices and process for their production |
| US5024841A (en) * | 1988-06-30 | 1991-06-18 | Collagen Corporation | Collagen wound healing matrices and process for their production |
| GB8827305D0 (en) * | 1988-11-23 | 1988-12-29 | British Bio Technology | Compounds |
| US5227168A (en) * | 1989-11-21 | 1993-07-13 | Bruce Barber | Method of treating a wound |
| US5308839A (en) * | 1989-12-04 | 1994-05-03 | The Research Foundation Of State University Of New York | Composition comprising non-steroidal anti-inflammatory agent tenidap and effectively non-antibacterial tetracycline |
| JP3016587B2 (ja) * | 1989-12-04 | 2000-03-06 | ザ・リサーチ・ファンデーション・オブ・ステート・ユニバーシティ・オブ・ニューヨーク | 非ステロイド抗炎症剤及びテトラサイクリンの配合 |
| GB9000846D0 (en) * | 1990-01-15 | 1990-03-14 | Beecham Group Plc | Novel compounds |
| US5008283A (en) * | 1990-03-19 | 1991-04-16 | Pfizer Inc. | Use of tenidap to inhibit activation of collagenase and to inhibit the activity of myeloperoxidase |
| GB9008065D0 (en) * | 1990-04-10 | 1990-06-06 | Beecham Group Plc | Novel compounds |
| US5081106A (en) * | 1990-07-16 | 1992-01-14 | The Oregon Health Sciences University | Wound dressing protocol utilizing collagen gelatin formed with iodine |
| US5156601A (en) * | 1991-03-20 | 1992-10-20 | Hydromer, Inc. | Tacky, hydrophilic gel dressings and products therefrom |
| US5229380A (en) * | 1991-06-28 | 1993-07-20 | Harris Richard Y | Method for treating helicobacter pylori gastritis |
| US5258371A (en) * | 1992-05-29 | 1993-11-02 | Kuraray Co., Ltd. | Method to reduce connective tissue destruction |
| DE69304292T2 (de) * | 1992-11-17 | 1997-01-02 | Univ New York | Tetracycline inclusive nicht antimicrobiel wirksame, chemisch modifizierte Tetracycline hemmende exzessive Kollagenquervernetzung bei Diabetes |
-
1996
- 1996-08-01 US US08/691,135 patent/US5827840A/en not_active Expired - Lifetime
-
1997
- 1997-08-01 WO PCT/US1997/013534 patent/WO1998005340A1/en not_active Ceased
- 1997-08-01 DK DK97935248T patent/DK0923378T3/da active
- 1997-08-01 ES ES97935248T patent/ES2255107T3/es not_active Expired - Lifetime
- 1997-08-01 EP EP97935248A patent/EP0923378B1/en not_active Expired - Lifetime
- 1997-08-01 CA CA002261805A patent/CA2261805C/en not_active Expired - Fee Related
- 1997-08-01 JP JP10508075A patent/JP2000516214A/ja active Pending
- 1997-08-01 DE DE69734661T patent/DE69734661T2/de not_active Expired - Lifetime
- 1997-08-01 KR KR10-1999-7000866A patent/KR100494206B1/ko not_active Expired - Fee Related
- 1997-08-01 AT AT97935248T patent/ATE309804T1/de active
- 1997-08-01 AU AU38234/97A patent/AU3823497A/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| WO1998005340A1 (en) | 1998-02-12 |
| US5827840A (en) | 1998-10-27 |
| KR100494206B1 (ko) | 2005-06-13 |
| ES2255107T3 (es) | 2006-06-16 |
| ATE309804T1 (de) | 2005-12-15 |
| EP0923378A1 (en) | 1999-06-23 |
| CA2261805A1 (en) | 1998-02-12 |
| CA2261805C (en) | 2008-11-04 |
| KR20000029753A (ko) | 2000-05-25 |
| EP0923378A4 (en) | 2000-11-15 |
| AU3823497A (en) | 1998-02-25 |
| EP0923378B1 (en) | 2005-11-16 |
| JP2000516214A (ja) | 2000-12-05 |
| DE69734661D1 (de) | 2005-12-22 |
| DE69734661T2 (de) | 2006-08-10 |
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