ATE310504T1 - Arzneizusammensetzungen enthaltend ascomycinderivate - Google Patents

Arzneizusammensetzungen enthaltend ascomycinderivate

Info

Publication number: ATE310504T1
Authority: AT; Austria
Prior art keywords: compositions containing; phosphatidylglycerol; medicinal compositions; sub; salt
Prior art date: 1996-01-19

Application number

AT02022257T

Other languages

English (en)

Inventor

Harry Tiemessen

Original Assignee

Novartis Pharma Gmbh

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1996-01-19

Filing date

1997-01-20

Publication date

2005-12-15

1997-01-20 Application filed by Novartis Pharma Gmbh filed Critical Novartis Pharma Gmbh

2005-12-15 Application granted granted Critical

2005-12-15 Publication of ATE310504T1 publication Critical patent/ATE310504T1/de

Links

ZDQSOHOQTUFQEM-PKUCKEGBSA-N ascomycin Chemical class C/C([C@H]1OC(=O)[C@@H]2CCCCN2C(=O)C(=O)[C@]2(O)O[C@@H]([C@H](C[C@H]2C)OC)[C@@H](OC)C[C@@H](C)C\C(C)=C/[C@H](C(C[C@H](O)[C@H]1C)=O)CC)=C\[C@@H]1CC[C@@H](O)[C@H](OC)C1 ZDQSOHOQTUFQEM-PKUCKEGBSA-N 0.000 title abstract 2
239000000203 mixture Substances 0.000 title abstract 2
PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 abstract 3
239000013543 active substance Substances 0.000 abstract 2
239000000839 emulsion Substances 0.000 abstract 2
238000000034 method Methods 0.000 abstract 2
150000003839 salts Chemical class 0.000 abstract 2
239000003381 stabilizer Substances 0.000 abstract 2
HVCOBJNICQPDBP-UHFFFAOYSA-N 3-[3-[3,5-dihydroxy-6-methyl-4-(3,4,5-trihydroxy-6-methyloxan-2-yl)oxyoxan-2-yl]oxydecanoyloxy]decanoic acid;hydrate Chemical compound O.OC1C(OC(CC(=O)OC(CCCCCCC)CC(O)=O)CCCCCCC)OC(C)C(O)C1OC1C(O)C(O)C(O)C(C)O1 HVCOBJNICQPDBP-UHFFFAOYSA-N 0.000 abstract 1
229930186217 Glycolipid Natural products 0.000 abstract 1
ZDQSOHOQTUFQEM-XCXYXIJFSA-N ascomycin Natural products CC[C@H]1C=C(C)C[C@@H](C)C[C@@H](OC)[C@H]2O[C@@](O)([C@@H](C)C[C@H]2OC)C(=O)C(=O)N3CCCC[C@@H]3C(=O)O[C@H]([C@H](C)[C@@H](O)CC1=O)C(=C[C@@H]4CC[C@@H](O)[C@H](C4)OC)C ZDQSOHOQTUFQEM-XCXYXIJFSA-N 0.000 abstract 1
239000003795 chemical substances by application Substances 0.000 abstract 1
239000012141 concentrate Substances 0.000 abstract 1
235000014113 dietary fatty acids Nutrition 0.000 abstract 1
229930195729 fatty acid Natural products 0.000 abstract 1
239000000194 fatty acid Substances 0.000 abstract 1
150000004665 fatty acids Chemical class 0.000 abstract 1
238000001990 intravenous administration Methods 0.000 abstract 1
239000002960 lipid emulsion Substances 0.000 abstract 1
238000004519 manufacturing process Methods 0.000 abstract 1
239000003960 organic solvent Substances 0.000 abstract 1
150000003904 phospholipids Chemical class 0.000 abstract 1
229940068196 placebo Drugs 0.000 abstract 1
239000000902 placebo Substances 0.000 abstract 1
229920006395 saturated elastomer Polymers 0.000 abstract 1
150000003408 sphingolipids Chemical class 0.000 abstract 1

Classifications

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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/12—Carboxylic acids; Salts or anhydrides thereof
- A—HUMAN NECESSITIES
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- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
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- A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
- A61K31/436—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a six-membered ring having oxygen as a ring hetero atom, e.g. rapamycin
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Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Veterinary Medicine (AREA)
Medicinal Chemistry (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Animal Behavior & Ethology (AREA)
Pharmacology & Pharmacy (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Engineering & Computer Science (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Organic Chemistry (AREA)
Bioinformatics & Cheminformatics (AREA)
Epidemiology (AREA)
Dermatology (AREA)
Immunology (AREA)
Oil, Petroleum & Natural Gas (AREA)
Diabetes (AREA)
Molecular Biology (AREA)
Biophysics (AREA)
Physical Education & Sports Medicine (AREA)
Dispersion Chemistry (AREA)
Pulmonology (AREA)
Ophthalmology & Optometry (AREA)
Communicable Diseases (AREA)
Oncology (AREA)
Hematology (AREA)
Orthopedic Medicine & Surgery (AREA)
Rheumatology (AREA)
Neurology (AREA)
Pain & Pain Management (AREA)
Biomedical Technology (AREA)
Obesity (AREA)
Emergency Medicine (AREA)
Virology (AREA)
Tropical Medicine & Parasitology (AREA)
Neurosurgery (AREA)
Gastroenterology & Hepatology (AREA)

AT02022257T 1996-01-19 1997-01-20 Arzneizusammensetzungen enthaltend ascomycinderivate ATE310504T1 (de)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
GBGB9601120.0A GB9601120D0 (en)	1996-01-19	1996-01-19	Organic compounds

Publications (1)

Publication Number	Publication Date
ATE310504T1 true ATE310504T1 (de)	2005-12-15

Family

ID=10787276

Family Applications (4)

Application Number	Title	Priority Date	Filing Date
AT02022257T ATE310504T1 (de)	1996-01-19	1997-01-20	Arzneizusammensetzungen enthaltend ascomycinderivate
AT97901563T ATE239449T1 (de)	1996-01-19	1997-01-20	(3'-desoxy-3-oxo-mebmt)1-(val)2-ciclosporin enthaltende arzneimittelemulsion
AT05018663T ATE510532T1 (de)	1996-01-19	1997-01-20	Arzneizusammensetzungen enthaltend rapamycinderivate
AT02022256T ATE304842T1 (de)	1996-01-19	1997-01-20	Arzneizusammensetzungen enthaltend rapamycinderivate

Family Applications After (3)

Application Number	Title	Priority Date	Filing Date
AT97901563T ATE239449T1 (de)	1996-01-19	1997-01-20	(3'-desoxy-3-oxo-mebmt)1-(val)2-ciclosporin enthaltende arzneimittelemulsion
AT05018663T ATE510532T1 (de)	1996-01-19	1997-01-20	Arzneizusammensetzungen enthaltend rapamycinderivate
AT02022256T ATE304842T1 (de)	1996-01-19	1997-01-20	Arzneizusammensetzungen enthaltend rapamycinderivate

Country Status (14)

Country	Link
US (2)	US6239102B1 (de)
EP (4)	EP0874621B1 (de)
JP (2)	JP4077386B2 (de)
KR (1)	KR100485146B1 (de)
AT (4)	ATE310504T1 (de)
AU (1)	AU1543497A (de)
CA (2)	CA2240339C (de)
DE (3)	DE69734253T2 (de)
DK (4)	DK1273289T3 (de)
ES (4)	ES2365734T3 (de)
GB (1)	GB9601120D0 (de)
HK (2)	HK1054183B (de)
PT (2)	PT874621E (de)
WO (1)	WO1997025977A1 (de)

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US20030199425A1 (en) *	1997-06-27	2003-10-23	Desai Neil P.	Compositions and methods for treatment of hyperplasia
US20030220234A1 (en)	1998-11-02	2003-11-27	Selvaraj Naicker	Deuterated cyclosporine analogs and their use as immunodulating agents
WO1999029316A1 (en)	1997-12-10	1999-06-17	Severson, Mary, L.	Pharmaceutical compositions containing an omega-3 fatty acid oil
DE19810655A1 (de) *	1998-03-12	1999-09-16	Univ Eberhard Karls	Arzneimittel mit einem Gehalt an Ciclosporin
US6979456B1 (en)	1998-04-01	2005-12-27	Jagotec Ag	Anticancer compositions
AR018376A1 (es)	1998-05-26	2001-11-14	Novartis Ag	Composiciones farmaceuticas que se pueden dispersar de una manera espontanea y el uso de las mismas para la manufactura de un medicamento
US7265150B1 (en) *	1998-08-14	2007-09-04	Gpi Nil Holdings Inc.	Carboxylic acids and carboxylic acid isosteres of N-heterocyclic compounds for vision and memory disorders
US6376517B1 (en) *	1998-08-14	2002-04-23	Gpi Nil Holdings, Inc.	Pipecolic acid derivatives for vision and memory disorders
US7063857B1 (en)	1999-04-30	2006-06-20	Sucampo Ag	Use of macrolide compounds for the treatment of dry eye
WO2000066122A1 (en) *	1999-04-30	2000-11-09	Sucampo Ag	Use of macrolide compounds for the treatment of dry eye
DE60044717D1 (de)	1999-05-10	2010-09-02	Paolo Brenner	Kombination von immunsuppressiven substanzen zur behandlung oder vorbeugung von transplantat abstossungen
US6720001B2 (en) *	1999-10-18	2004-04-13	Lipocine, Inc.	Emulsion compositions for polyfunctional active ingredients
NZ525243A (en)	2000-10-31	2005-01-28	Pharma Mar S	A lyophilised formulation comprising kahalalide F, a peptide isolated from a herbivorous marine species of mollusc, Elysia rufescens, to treat cancer
MX368013B (es)	2001-02-19	2019-09-13	Novartis Ag	Tratamiento de cáncer.
US20050019372A1 (en) *	2001-07-10	2005-01-27	Barbara E Corkey	Modified-fat nutritional products useful preventing or treating obesity
US20040137066A1 (en) *	2001-11-26	2004-07-15	Swaminathan Jayaraman	Rationally designed therapeutic intravascular implant coating
US6641611B2 (en)	2001-11-26	2003-11-04	Swaminathan Jayaraman	Therapeutic coating for an intravascular implant
MXPA04003625A (es)	2001-10-19	2004-12-02	Sotechnika Inc	Sintesis de analogos de ciclosporina.
JP2006522007A (ja) *	2002-11-15	2006-09-28	ノバルティスアクチエンゲゼルシャフト	ドラッグ・デリバリー・システム
GB0307866D0 (en) *	2003-04-04	2003-05-14	Novartis Ag	Pharmaceutical composition
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1996
- 1996-01-19 GB GBGB9601120.0A patent/GB9601120D0/en active Pending
1997
- 1997-01-20 CA CA2240339A patent/CA2240339C/en not_active Expired - Lifetime
- 1997-01-20 DK DK02022257T patent/DK1273289T3/da active
- 1997-01-20 WO PCT/EP1997/000252 patent/WO1997025977A1/en not_active Ceased
- 1997-01-20 EP EP97901563A patent/EP0874621B1/de not_active Expired - Lifetime
- 1997-01-20 ES ES05018663T patent/ES2365734T3/es not_active Expired - Lifetime
- 1997-01-20 DK DK97901563T patent/DK0874621T3/da active
- 1997-01-20 EP EP02022256A patent/EP1273288B1/de not_active Expired - Lifetime
- 1997-01-20 US US09/091,072 patent/US6239102B1/en not_active Ceased
- 1997-01-20 ES ES97901563T patent/ES2199338T3/es not_active Expired - Lifetime
- 1997-01-20 AT AT02022257T patent/ATE310504T1/de active
- 1997-01-20 PT PT97901563T patent/PT874621E/pt unknown
- 1997-01-20 AT AT97901563T patent/ATE239449T1/de active
- 1997-01-20 AT AT05018663T patent/ATE510532T1/de active
- 1997-01-20 KR KR10-1998-0704696A patent/KR100485146B1/ko not_active Expired - Lifetime
- 1997-01-20 DE DE69734253T patent/DE69734253T2/de not_active Expired - Lifetime
- 1997-01-20 AT AT02022256T patent/ATE304842T1/de active
- 1997-01-20 DE DE69734742T patent/DE69734742T2/de not_active Expired - Lifetime
- 1997-01-20 CA CA002678707A patent/CA2678707A1/en not_active Abandoned
- 1997-01-20 DK DK05018663.4T patent/DK1679064T3/da active
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- 1997-01-20 PT PT05018663T patent/PT1679064E/pt unknown
- 1997-01-20 DK DK02022256T patent/DK1273288T3/da active
- 1997-01-20 ES ES02022257T patent/ES2253483T3/es not_active Expired - Lifetime
- 1997-01-20 ES ES02022256T patent/ES2247245T3/es not_active Expired - Lifetime
- 1997-01-20 US US10/345,665 patent/USRE42014E1/en not_active Expired - Lifetime
1999
- 1999-02-05 HK HK03104827.8A patent/HK1054183B/en not_active IP Right Cessation
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2003
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Also Published As

Publication number	Publication date
PT874621E (pt)	2003-09-30
DK0874621T3 (da)	2003-09-01
EP1273289A1 (de)	2003-01-08
HK1054183B (en)	2006-07-28
EP1679064B1 (de)	2011-05-25
EP0874621B1 (de)	2003-05-07
WO1997025977A1 (en)	1997-07-24
HK1015277A1 (en)	1999-10-15
JP3763581B2 (ja)	2006-04-05
ATE304842T1 (de)	2005-10-15
EP1679064A3 (de)	2009-10-07
CA2240339A1 (en)	1997-07-24
CA2240339C (en)	2010-11-16
ATE510532T1 (de)	2011-06-15
HK1053973B (en)	2006-09-29
JP2007246543A (ja)	2007-09-27
ATE239449T1 (de)	2003-05-15
AU1543497A (en)	1997-08-11
HK1054183A1 (en)	2003-11-21
EP1273288A1 (de)	2003-01-08
USRE42014E1 (en)	2010-12-28
DE69734742D1 (de)	2005-12-29
DK1679064T3 (da)	2011-09-12
KR19990076603A (ko)	1999-10-15
DE69734253D1 (de)	2006-02-02
DE69734742T2 (de)	2006-07-27
EP1679064A2 (de)	2006-07-12
EP1273289B1 (de)	2005-11-23
DE69721729D1 (de)	2003-06-12
HK1053973A1 (en)	2003-11-14
DE69721729T2 (de)	2003-12-11
KR100485146B1 (ko)	2005-10-12
DK1273289T3 (da)	2006-03-20
GB9601120D0 (en)	1996-03-20
ES2247245T3 (es)	2006-03-01
US6239102B1 (en)	2001-05-29
ES2365734T3 (es)	2011-10-10
JP4077386B2 (ja)	2008-04-16
ES2199338T3 (es)	2004-02-16
DK1273288T3 (da)	2005-11-21
PT1679064E (pt)	2011-07-25
EP1273288B1 (de)	2005-09-21
JP2000503655A (ja)	2000-03-28
CA2678707A1 (en)	1997-07-24
EP0874621A1 (de)	1998-11-04
ES2253483T3 (es)	2006-06-01
DE69734253T2 (de)	2006-07-06
JP2004107350A (ja)	2004-04-08

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