ATE310511T1 - Verwendung von konjugierten linoleinsäure zur behandlung von type ii diabetes - Google Patents
Verwendung von konjugierten linoleinsäure zur behandlung von type ii diabetesInfo
- Publication number
- ATE310511T1 ATE310511T1 AT98963884T AT98963884T ATE310511T1 AT E310511 T1 ATE310511 T1 AT E310511T1 AT 98963884 T AT98963884 T AT 98963884T AT 98963884 T AT98963884 T AT 98963884T AT E310511 T1 ATE310511 T1 AT E310511T1
- Authority
- AT
- Austria
- Prior art keywords
- cis
- octadecadienoic acid
- diabetes
- trans
- linoleic acid
- Prior art date
Links
- JBYXPOFIGCOSSB-GOJKSUSPSA-N 9-cis,11-trans-octadecadienoic acid Chemical compound CCCCCC\C=C\C=C/CCCCCCCC(O)=O JBYXPOFIGCOSSB-GOJKSUSPSA-N 0.000 title 1
- 229940108924 conjugated linoleic acid Drugs 0.000 title 1
- OYHQOLUKZRVURQ-IXWMQOLASA-N linoleic acid Natural products CCCCC\C=C/C\C=C\CCCCCCCC(O)=O OYHQOLUKZRVURQ-IXWMQOLASA-N 0.000 title 1
- 208000001072 type 2 diabetes mellitus Diseases 0.000 title 1
- 239000000203 mixture Substances 0.000 abstract 4
- 235000013305 food Nutrition 0.000 abstract 3
- JBYXPOFIGCOSSB-QRLRYFCNSA-N 9Z,11Z-octadecadienoic acid Chemical compound CCCCCC\C=C/C=C\CCCCCCCC(O)=O JBYXPOFIGCOSSB-QRLRYFCNSA-N 0.000 abstract 2
- 206010012601 diabetes mellitus Diseases 0.000 abstract 2
- GKJZMAHZJGSBKD-UHFFFAOYSA-N (10E,12E)-Octadeca-9,11-dienoic acid Natural products CCCCCC=CC=CCCCCCCCCC(O)=O GKJZMAHZJGSBKD-UHFFFAOYSA-N 0.000 abstract 1
- GKJZMAHZJGSBKD-NMMTYZSQSA-N (10E,12Z)-octadecadienoic acid Chemical compound CCCCC\C=C/C=C/CCCCCCCCC(O)=O GKJZMAHZJGSBKD-NMMTYZSQSA-N 0.000 abstract 1
- GKJZMAHZJGSBKD-BLHCBFLLSA-N (10e,12e)-octadeca-10,12-dienoic acid Chemical compound CCCCC\C=C\C=C\CCCCCCCCC(O)=O GKJZMAHZJGSBKD-BLHCBFLLSA-N 0.000 abstract 1
- GKJZMAHZJGSBKD-ANYPYVPJSA-N 10-trans-12-cis-linoleic acid Natural products CCCCCC=C\C=C\CCCCCCCCC(O)=O GKJZMAHZJGSBKD-ANYPYVPJSA-N 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 150000002148 esters Chemical class 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
- A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/115—Fatty acids or derivatives thereof; Fats or oils
- A23L33/12—Fatty acids or derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Emergency Medicine (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Diabetes (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Polymers & Plastics (AREA)
- Food Science & Technology (AREA)
- Nutrition Science (AREA)
- Mycology (AREA)
- Epidemiology (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Obesity (AREA)
- Hematology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Endocrinology (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines Containing Plant Substances (AREA)
- Steroid Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US6956797P | 1997-12-12 | 1997-12-12 | |
| PCT/US1998/026469 WO1999029317A1 (en) | 1997-12-12 | 1998-12-11 | Methods and compositions for treating diabetes |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE310511T1 true ATE310511T1 (de) | 2005-12-15 |
Family
ID=22089860
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT98963884T ATE310511T1 (de) | 1997-12-12 | 1998-12-11 | Verwendung von konjugierten linoleinsäure zur behandlung von type ii diabetes |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US20050282897A1 (de) |
| EP (1) | EP1037624B1 (de) |
| JP (1) | JP2001525364A (de) |
| AT (1) | ATE310511T1 (de) |
| AU (1) | AU1911999A (de) |
| CA (1) | CA2313626A1 (de) |
| DE (1) | DE69832520T2 (de) |
| ES (1) | ES2252874T3 (de) |
| WO (1) | WO1999029317A1 (de) |
Families Citing this family (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6440931B1 (en) * | 1999-02-23 | 2002-08-27 | Natural Corporation | Conjugated linoleic acid in treatment and prophylaxis of diabetes |
| EP1231913A2 (de) * | 1999-07-09 | 2002-08-21 | Pharmacia Corporation | Behandlung von cyclooxygenase-2 bedingten erkrankungen unter verwendung von conjugierten fettsäureverbindungen |
| AU7073400A (en) | 1999-08-27 | 2001-03-26 | Eli Lilly And Company | Biaryl-oxa(thia)zole derivatives and their use as ppars modulators |
| JP5226912B2 (ja) * | 2000-06-12 | 2013-07-03 | 花王株式会社 | Ｐｐａｒ活性化剤 |
| US6927239B1 (en) | 2000-08-02 | 2005-08-09 | Pharmanutrients | Methods and compositions for the attenuation and/or prevention of stress/catabolic responses |
| EP1305018A4 (de) * | 2000-08-02 | 2006-08-30 | Pharmanutrients | Methoden und zusammenstellungen zur prophylaxe und/oder behandlung von diabetes und zur glukoseregulierung |
| US6838451B1 (en) | 2000-08-02 | 2005-01-04 | Pharmanutrients | Methods and compositions for the prevention and treatment of inflammation, osteoarthritis, and other degenerative joint diseases |
| JP2004505041A (ja) | 2000-08-02 | 2004-02-19 | ファーマニュートリエンツ | シンドロームｘの予防及び治療のための方法及び組成物 |
| DE10045059A1 (de) * | 2000-09-12 | 2002-03-21 | Basf Ag | Therapeutische Kombination von Liponsäure und Konjuensäuren zur Behandlung diabetischer Störungen |
| DE10102050A1 (de) | 2001-01-17 | 2002-07-18 | Basf Ag | Zubereitung zur Verbesserung der Nahrungsverwertung |
| EP1373182A1 (de) | 2001-03-29 | 2004-01-02 | Basf Aktiengesellschaft | Konjugierte ungesättigte glyceridgemische und verfahren zur ihrer herstellung |
| EP1302114A3 (de) * | 2001-10-16 | 2004-01-14 | Loders Croklaan B.V. | Mischungen zur Förderung der Glucoseaufnahme |
| US6888016B2 (en) | 2001-10-16 | 2005-05-03 | Loders Croklaan Usa Llc | Mixtures for stimulating glucose up-take |
| EP2214481B1 (de) | 2007-10-15 | 2019-05-01 | United Animal Health, Inc. | Verfahren zur erhöhung der leistung von nachkommen |
| RU2546291C2 (ru) * | 2008-08-14 | 2015-04-10 | Нестек С.А. | Композиции и способы воздействия на насыщение, липидный метаболизм и потребление жира |
| WO2013117744A2 (en) | 2012-02-09 | 2013-08-15 | Nogra Pharma Limited | Methods of treating fibrosis |
| US11255866B2 (en) | 2015-02-26 | 2022-02-22 | Wisconsin Alumni Research Foundation | Methods for predicting glucoregulatory dysfunction via diacylglycerol fatty acid species concentrations |
| MA43682A (fr) * | 2016-02-26 | 2018-11-28 | Nogra Pharma Ltd | Procédés de traitement de l'intolérance au lactose |
| AU2020217884B2 (en) | 2019-02-08 | 2025-02-20 | Nogra Pharma Limited | Process of making 3-(4'-aminophenyl)-2-methoxypropionic acid, and analogs and intermediates thereof |
Family Cites Families (26)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2490631A1 (fr) * | 1980-09-24 | 1982-03-26 | Roussel Uclaf | Nouvelle composition lipidique utilisable en dietetique, reanimation et therapeutique |
| US4472432A (en) * | 1982-05-12 | 1984-09-18 | Inabata & Co., Ltd. | Medicinal use of α,β-unsaturated fatty acids |
| GB8302708D0 (en) * | 1983-02-01 | 1983-03-02 | Efamol Ltd | Pharmaceutical and dietary composition |
| US4871768A (en) * | 1984-07-12 | 1989-10-03 | New England Deaconess Hospital Corporation | Dietary supplement utilizing ω-3/medium chain trigylceride mixtures |
| US5034415A (en) * | 1987-08-07 | 1991-07-23 | Century Laboratories, Inc. | Treatment of diabetes mellitus |
| US5017614A (en) * | 1989-02-17 | 1991-05-21 | Wisconsin Alumni Research Foundation | Methods of preventing oxidation, quenching singlet oxygen and inhibiting mold growth and novel compositions therefor |
| US5070104A (en) * | 1989-02-17 | 1991-12-03 | Wisconsin Alumni Research Foundation | Methods of chelating metal and novel compositions therefor |
| US5208356A (en) * | 1989-02-17 | 1993-05-04 | Wisconsin Alumni Research Foundation | Octadecadienoic phospholipic esters, antioxidant and mold inhibiting compositions |
| US5428072A (en) * | 1992-04-29 | 1995-06-27 | Wisconsin Alumni Research Foundation | Method of increasing the efficiency of feed conversion in animals |
| US5674901A (en) * | 1995-06-01 | 1997-10-07 | Wisconsin Alumni Research Foundation | Methods of treating animals to maintain or increase CD-4 and CD-8 cell populations |
| US5554646A (en) * | 1992-04-29 | 1996-09-10 | Wisconsin Alumni Research Foundation | Method for reducing body fat in animals |
| US5430066A (en) * | 1992-04-29 | 1995-07-04 | Wisconsin Alumni Research Foundation | Methods for preventing weight loss, reduction in weight gain, and anorexia due to immune stimulation |
| US5504114A (en) * | 1992-04-29 | 1996-04-02 | Wisconsin Alumni Research Foundation | Method for controlling bird populations |
| AU683027B2 (en) * | 1993-01-27 | 1997-10-30 | Scotia Holdings Plc | Triglycerides |
| NL9300848A (nl) * | 1993-05-14 | 1994-12-01 | Friesland Frico Domo Coop | Werkwijze voor de bereiding van lang houdbare melkconcentraten en melkpoeders. |
| FR2723315B1 (fr) * | 1994-08-02 | 1996-10-25 | Cird Galderma | Procede et composition pour stimuler la differenciation des cellules preadipocytaires et traitements therapeutiques associes |
| US5760082C1 (en) * | 1994-08-29 | 2001-03-06 | Wisconsin Alumni Res Found | Dietetic foods containing conjugated linoleic acids |
| US5518751A (en) * | 1994-09-08 | 1996-05-21 | Friesland Brands B.V. | Process for the preparation of milk concentrates and milk powders having a long storage life |
| GB9508823D0 (en) * | 1995-05-01 | 1995-06-21 | Scotia Holdings Plc | Drug Derivatives |
| US5585400A (en) * | 1996-02-27 | 1996-12-17 | Wisconsin Alumni Research Foundation | Methods of attenuating the allergic response in animals |
| US5760083A (en) * | 1996-08-07 | 1998-06-02 | Wisconsin Alumni Research Foundation | Use of CLA to reduce the incidence of valgus and varus leg deforomities in poultry |
| US5804210A (en) * | 1996-08-07 | 1998-09-08 | Wisconsin Alumni Research Foundation | Methods of treating animals to maintain or enhance bone mineral content and compositions for use therein |
| GB9620248D0 (en) * | 1996-09-26 | 1996-11-13 | Scotia Holdings Plc | Esters of unsaturated fatty acids |
| US5770247A (en) * | 1996-10-03 | 1998-06-23 | Wisconsin Alumni Research Foundation | Method of increasing the CLA content of cow's milK |
| US7015249B1 (en) * | 1997-12-12 | 2006-03-21 | Purdue Research Foundation | Methods and compositions for treating diabetes |
| US6440931B1 (en) * | 1999-02-23 | 2002-08-27 | Natural Corporation | Conjugated linoleic acid in treatment and prophylaxis of diabetes |
-
1998
- 1998-12-11 WO PCT/US1998/026469 patent/WO1999029317A1/en not_active Ceased
- 1998-12-11 AU AU19119/99A patent/AU1911999A/en not_active Abandoned
- 1998-12-11 JP JP2000523988A patent/JP2001525364A/ja not_active Withdrawn
- 1998-12-11 AT AT98963884T patent/ATE310511T1/de not_active IP Right Cessation
- 1998-12-11 EP EP98963884A patent/EP1037624B1/de not_active Expired - Lifetime
- 1998-12-11 DE DE69832520T patent/DE69832520T2/de not_active Expired - Fee Related
- 1998-12-11 CA CA002313626A patent/CA2313626A1/en not_active Abandoned
- 1998-12-11 ES ES98963884T patent/ES2252874T3/es not_active Expired - Lifetime
-
2005
- 2005-07-28 US US11/191,540 patent/US20050282897A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| ES2252874T3 (es) | 2006-05-16 |
| DE69832520T2 (de) | 2006-08-10 |
| US20050282897A1 (en) | 2005-12-22 |
| DE69832520D1 (de) | 2005-12-29 |
| CA2313626A1 (en) | 1999-06-17 |
| EP1037624B1 (de) | 2005-11-23 |
| EP1037624A1 (de) | 2000-09-27 |
| JP2001525364A (ja) | 2001-12-11 |
| WO1999029317A1 (en) | 1999-06-17 |
| EP1037624A4 (de) | 2002-05-15 |
| AU1911999A (en) | 1999-06-28 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |