ATE311389T1 - Wirkstoffvorläufer von imidazopyridin-derivaten - Google Patents

Wirkstoffvorläufer von imidazopyridin-derivaten

Info

Publication number
ATE311389T1
ATE311389T1 AT01933769T AT01933769T ATE311389T1 AT E311389 T1 ATE311389 T1 AT E311389T1 AT 01933769 T AT01933769 T AT 01933769T AT 01933769 T AT01933769 T AT 01933769T AT E311389 T1 ATE311389 T1 AT E311389T1
Authority
AT
Austria
Prior art keywords
precursor
imidazopyridine derivatives
imidazopyridine
derivatives
substituents
Prior art date
Application number
AT01933769T
Other languages
English (en)
Inventor
Wolfgang-Alexander Simon
Stefan Postius
Reinhard Huber
Wolfgang Kromer
Joerg Senn-Bilfinger
Wilm Buhr
Original Assignee
Altana Pharma Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Altana Pharma Ag filed Critical Altana Pharma Ag
Application granted granted Critical
Publication of ATE311389T1 publication Critical patent/ATE311389T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains three hetero rings
    • C07D471/14—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/12—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains three hetero rings
    • C07D491/14—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/07—Optical isomers

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
AT01933769T 2000-03-29 2001-03-28 Wirkstoffvorläufer von imidazopyridin-derivaten ATE311389T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP00106695 2000-03-29
PCT/EP2001/003514 WO2001072756A1 (en) 2000-03-29 2001-03-28 Prodrugs of imidazopyridine derivatives

Publications (1)

Publication Number Publication Date
ATE311389T1 true ATE311389T1 (de) 2005-12-15

Family

ID=8168271

Family Applications (1)

Application Number Title Priority Date Filing Date
AT01933769T ATE311389T1 (de) 2000-03-29 2001-03-28 Wirkstoffvorläufer von imidazopyridin-derivaten

Country Status (25)

Country Link
US (2) US20030125327A1 (de)
EP (1) EP1313740B1 (de)
JP (1) JP2003528878A (de)
KR (1) KR100860627B1 (de)
CN (1) CN1214030C (de)
AT (1) ATE311389T1 (de)
AU (1) AU783633B2 (de)
BR (1) BR0109483A (de)
CA (1) CA2404474A1 (de)
CZ (1) CZ20023194A3 (de)
DE (1) DE60115466T2 (de)
DK (1) DK1313740T3 (de)
EA (1) EA005597B1 (de)
ES (1) ES2253376T3 (de)
HR (1) HRP20020854A2 (de)
HU (1) HUP0302331A2 (de)
IL (2) IL151200A0 (de)
MX (1) MXPA02009551A (de)
NO (1) NO20024662L (de)
NZ (1) NZ520837A (de)
PL (1) PL365116A1 (de)
SI (1) SI1313740T1 (de)
SK (1) SK286850B6 (de)
WO (1) WO2001072756A1 (de)
ZA (1) ZA200207637B (de)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2003528876A (ja) * 2000-03-29 2003-09-30 アルタナ ファルマ アクチエンゲゼルシャフト アルキル化されたイミダゾピリジン誘導体
EA008151B1 (ru) * 2000-10-25 2007-04-27 Алтана Фарма Аг Полизамещенные имидазопиридины в качестве ингибиторов желудочной секреции
CA2467652A1 (en) * 2001-11-19 2003-05-30 Altana Pharma Ag Reversible proton pump inhibitors for the treatment of airway disorders
US7314935B2 (en) 2002-02-15 2008-01-01 Altana Pharma Ag Tricyclic n-acyl compounds
TWI295575B (en) * 2002-04-24 2008-04-11 Altana Pharma Ag Nitrosated imidazopyridines
RS95304A (sr) * 2002-05-07 2006-12-15 Altana Pharma Ag. Nova kombinacija za tretman oboljenja disajnih puteva
AU2003288071A1 (en) 2002-11-19 2004-06-15 Altana Pharma Ag 8-substituted imidazopyridines
HRP20050632A2 (hr) * 2002-12-20 2006-04-30 Altana Pharma Ag Silil eteri
MXPA05008490A (es) * 2003-02-17 2005-10-18 Altana Pharma Ag Combinaciones que contienen imidazopiridinas y su uso en el tratamiento de enfermedades gastrointestinales inflamatorias.
AR044129A1 (es) 2003-05-06 2005-08-24 Altana Pharma Ag Compuestos intermedios de imidazopiridina. proceso de preparacion.
SA04250092B1 (ar) * 2003-05-14 2008-05-04 التانا فاروا ايه جي مركب وسيط جديد لتحضير مركبات إيميدازوبيريدين imidazopyridines فعالة علاجياً
WO2004105795A1 (en) * 2003-05-27 2004-12-09 Altana Pharma Ag Pharmaceutical combinations of a proton pump inhibitor and a compound which modifies gastrointestinal motility
KR20060099524A (ko) 2003-11-03 2006-09-19 아스트라제네카 아베 무증상 위식도 역류의 치료를 위한 이미다조[1,2-ａ]피리딘유도체
AR046893A1 (es) * 2003-12-16 2005-12-28 Altana Pharma Ag Bencimidazoles triciclicos
WO2005058894A1 (en) 2003-12-19 2005-06-30 Altana Pharma Ag Intermediates for the preparation of tricyclic dihydropyrano -imidazo -pyridines derivatives
US20080249310A1 (en) * 2004-07-23 2008-10-09 Thijs Kuilman Process For the Preparation of (2R,3R)-2-Hydroxy-3-Amino-3-Aryl-Propionamide and (2R,3R)-2-Hydroxy-3-Amino-3-Aryl-Propionic Acid Alkyl Ester
CA2582256A1 (en) * 2004-10-01 2006-04-13 Altana Pharma Ag Substituted tricyclic benzimidazoles
KR101605063B1 (ko) 2009-07-09 2016-03-21 라퀄리아 파마 인코포레이티드 소화관 운동이상이 관여하는 질환의 치료용 산 펌프 길항제

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4468400A (en) * 1982-12-20 1984-08-28 Schering Corporation Antiulcer tricyclic imidazo [1,2-a]pyridines
US4673679A (en) * 1986-05-14 1987-06-16 E. I. Du Pont De Nemours And Company Use of prodrugs of 3-hydroxymorphinans to prevent bitter taste upon buccal, nasal or sublingual administration
CA2102116A1 (en) * 1991-05-31 1992-12-01 Gary R. Schulte Use of rapamycin prodrugs as immunosuppressant agents
DE4308095A1 (de) * 1993-03-13 1994-09-15 Hoechst Ag Prodrug-Derivate von Arzneimittelwirkstoffen mit Hydroxylgruppen, Verfahren zu deren Herstellung und ihre Verwendung
SE9401197D0 (sv) * 1994-04-11 1994-04-11 Astra Ab Active compounds
US6073004A (en) 1996-12-17 2000-06-06 Ericsson Inc. Emergency call initiator
EP0971922B1 (de) * 1997-03-24 2004-04-28 ALTANA Pharma AG Tetrahydropyridoverbindungen
EA002402B1 (ru) * 1997-03-24 2002-04-25 Бык Гульден Ломберг Хемише Фабрик Гмбх Тетрагидропиридо-соединения
JP2001526703A (ja) * 1997-05-28 2001-12-18 ビイク グルデン ロンベルク ヒエーミツシエ フアブリーク ゲゼルシヤフト ミツト ベシユレンクテル ハフツング 縮合ジヒドロピラン
US6436953B1 (en) * 1998-09-23 2002-08-20 Byk Gulden Lomberg Chemische Fabrik Gmbh Tetrahydropyridoethers
EP1127059B1 (de) * 1998-11-03 2008-02-20 Nycomed GmbH Imidazonaphthyridine
JP2003528876A (ja) * 2000-03-29 2003-09-30 アルタナ ファルマ アクチエンゲゼルシャフト アルキル化されたイミダゾピリジン誘導体

Also Published As

Publication number Publication date
ZA200207637B (en) 2004-04-08
CA2404474A1 (en) 2001-10-04
KR20020084262A (ko) 2002-11-04
CN1214030C (zh) 2005-08-10
CZ20023194A3 (cs) 2003-01-15
EA005597B1 (ru) 2005-04-28
ES2253376T3 (es) 2006-06-01
DK1313740T3 (da) 2006-04-03
SK286850B6 (sk) 2009-06-05
NO20024662D0 (no) 2002-09-27
HK1056175A1 (en) 2004-02-06
US20030125327A1 (en) 2003-07-03
IL151200A (en) 2009-11-18
DE60115466D1 (de) 2006-01-05
EA200200875A1 (ru) 2003-04-24
CN1426414A (zh) 2003-06-25
PL365116A1 (en) 2004-12-27
SK13852002A3 (sk) 2003-02-04
EP1313740A1 (de) 2003-05-28
WO2001072756A1 (en) 2001-10-04
DE60115466T2 (de) 2006-07-20
AU783633B2 (en) 2005-11-17
EP1313740B1 (de) 2005-11-30
US20040198764A1 (en) 2004-10-07
MXPA02009551A (es) 2004-05-14
NO20024662L (no) 2002-09-27
SI1313740T1 (sl) 2006-04-30
US7189736B2 (en) 2007-03-13
HUP0302331A2 (hu) 2003-12-29
AU6016601A (en) 2001-10-08
HRP20020854A2 (en) 2004-12-31
JP2003528878A (ja) 2003-09-30
KR100860627B1 (ko) 2008-09-29
IL151200A0 (en) 2003-04-10
BR0109483A (pt) 2003-06-10
NZ520837A (en) 2005-01-28

Similar Documents

Publication Publication Date Title
YU21401A (sh) Tetrahidropiridoetri
ATE311389T1 (de) Wirkstoffvorläufer von imidazopyridin-derivaten
ATE332302T1 (de) Alkylierte imidazopyridinderivate
ATE386742T1 (de) Imidazonaphthyridine
DE69823493D1 (de) Tetrahydropyridoverbindungen
DE60127131D1 (de) Tricyclische imidazopyridine
DE60131968D1 (de) PYRANOÄ2,3-cÜIMIDAZOÄ1,2-aÜPYRIDIN-DERIVATE ZUR BEHANDLUNG VON GASTROINTESTINALEN ERKRANKUNGEN
DE60120398D1 (de) Imidazopyridin-8-one
IS8034A (is) Imídasó[4,5-B]kínólínafleiður og notkun þeirra sem NO-myndunarhemla
EA200500903A1 (ru) Силиловые простые эфиры
PE61999A1 (es) Compuestos de tetrahidropiridina

Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification

Ref document number: 1313740

Country of ref document: EP

REN Ceased due to non-payment of the annual fee