ATE352618T1 - Rezeptor 5, der eine für den zelltod verantwortliche domäne enthält - Google Patents
Rezeptor 5, der eine für den zelltod verantwortliche domäne enthältInfo
- Publication number
- ATE352618T1 ATE352618T1 AT98912966T AT98912966T ATE352618T1 AT E352618 T1 ATE352618 T1 AT E352618T1 AT 98912966 T AT98912966 T AT 98912966T AT 98912966 T AT98912966 T AT 98912966T AT E352618 T1 ATE352618 T1 AT E352618T1
- Authority
- AT
- Austria
- Prior art keywords
- receptor
- cell death
- proteins
- domain responsible
- antagonists
- Prior art date
Links
- 230000030833 cell death Effects 0.000 title 1
- 108060008682 Tumor Necrosis Factor Proteins 0.000 abstract 2
- 239000005557 antagonist Substances 0.000 abstract 2
- 102000003390 tumor necrosis factor Human genes 0.000 abstract 2
- 108050001718 Death domains Proteins 0.000 abstract 1
- 102000010170 Death domains Human genes 0.000 abstract 1
- 101000610604 Homo sapiens Tumor necrosis factor receptor superfamily member 10B Proteins 0.000 abstract 1
- 102000053594 human TNFRSF10B Human genes 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 102000039446 nucleic acids Human genes 0.000 abstract 1
- 108020004707 nucleic acids Proteins 0.000 abstract 1
- 150000007523 nucleic acids Chemical class 0.000 abstract 1
- 229920001184 polypeptide Polymers 0.000 abstract 1
- 102000004196 processed proteins & peptides Human genes 0.000 abstract 1
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 1
- 102000004169 proteins and genes Human genes 0.000 abstract 1
- 108090000623 proteins and genes Proteins 0.000 abstract 1
- 102000005962 receptors Human genes 0.000 abstract 1
- 108020003175 receptors Proteins 0.000 abstract 1
- 238000010188 recombinant method Methods 0.000 abstract 1
- 238000012216 screening Methods 0.000 abstract 1
- 239000013598 vector Substances 0.000 abstract 1
Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/715—Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons
- C07K14/7151—Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons for tumor necrosis factor [TNF], for lymphotoxin [LT]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Medicinal Chemistry (AREA)
- Biomedical Technology (AREA)
- Immunology (AREA)
- Molecular Biology (AREA)
- Zoology (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Neurosurgery (AREA)
- Wood Science & Technology (AREA)
- Cell Biology (AREA)
- Toxicology (AREA)
- General Engineering & Computer Science (AREA)
- Gastroenterology & Hepatology (AREA)
- Neurology (AREA)
- Physics & Mathematics (AREA)
- Plant Pathology (AREA)
- Urology & Nephrology (AREA)
- Transplantation (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Hospice & Palliative Care (AREA)
- Vascular Medicine (AREA)
- Microbiology (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US4084697P | 1997-03-17 | 1997-03-17 | |
| US5402197P | 1997-07-29 | 1997-07-29 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE352618T1 true ATE352618T1 (de) | 2007-02-15 |
Family
ID=26717514
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT98912966T ATE352618T1 (de) | 1997-03-17 | 1998-03-17 | Rezeptor 5, der eine für den zelltod verantwortliche domäne enthält |
Country Status (14)
| Country | Link |
|---|---|
| US (2) | US7803615B1 (de) |
| EP (1) | EP0970213B1 (de) |
| JP (2) | JP4330180B2 (de) |
| KR (1) | KR100527638B1 (de) |
| CN (2) | CN1624128A (de) |
| AT (1) | ATE352618T1 (de) |
| AU (1) | AU747635B2 (de) |
| CA (2) | CA2644454A1 (de) |
| DE (1) | DE69836956T2 (de) |
| DK (1) | DK0970213T3 (de) |
| ES (1) | ES2281126T3 (de) |
| NZ (2) | NZ337795A (de) |
| PT (1) | PT970213E (de) |
| WO (1) | WO1998041629A2 (de) |
Families Citing this family (83)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7429646B1 (en) | 1995-06-05 | 2008-09-30 | Human Genome Sciences, Inc. | Antibodies to human tumor necrosis factor receptor-like 2 |
| US7888466B2 (en) | 1996-01-11 | 2011-02-15 | Human Genome Sciences, Inc. | Human G-protein chemokine receptor HSATU68 |
| WO1997033904A1 (en) | 1996-03-12 | 1997-09-18 | Human Genome Sciences, Inc. | Death domain containing receptors |
| US7357927B2 (en) | 1996-03-12 | 2008-04-15 | Human Genome Sciences, Inc. | Death domain containing receptors |
| US6713061B1 (en) | 1996-03-12 | 2004-03-30 | Human Genome Sciences, Inc. | Death domain containing receptors |
| US6635743B1 (en) | 1996-03-22 | 2003-10-21 | Human Genome Sciences, Inc. | Apoptosis inducing molecule II and methods of use |
| US7964190B2 (en) | 1996-03-22 | 2011-06-21 | Human Genome Sciences, Inc. | Methods and compositions for decreasing T-cell activity |
| US8329179B2 (en) | 1997-01-28 | 2012-12-11 | Human Genome Sciences, Inc. | Death domain containing receptor 4 antibodies and methods |
| US7452538B2 (en) | 1997-01-28 | 2008-11-18 | Human Genome Sciences, Inc. | Death domain containing receptor 4 antibodies and methods |
| US6433147B1 (en) | 1997-01-28 | 2002-08-13 | Human Genome Sciences, Inc. | Death domain containing receptor-4 |
| PT1012274E (pt) | 1997-01-28 | 2007-08-14 | Craig A Rosen | Receptor 4 contendo um domínio de morte (dm4; receptor de morte 4), membro da super-família do ftn e ligação a liart (ap02) |
| US6072047A (en) * | 1997-02-13 | 2000-06-06 | Immunex Corporation | Receptor that binds trail |
| US7528239B1 (en) * | 1997-02-13 | 2009-05-05 | Immunex Corporation | Receptor that binds trail |
| US6872568B1 (en) * | 1997-03-17 | 2005-03-29 | Human Genome Sciences, Inc. | Death domain containing receptor 5 antibodies |
| US20050233958A1 (en) * | 1997-03-17 | 2005-10-20 | Human Genome Sciences, Inc. | Death domain containing receptor 5 |
| US20080248046A1 (en) * | 1997-03-17 | 2008-10-09 | Human Genome Sciences, Inc. | Death domain containing receptor 5 |
| JP4330180B2 (ja) | 1997-03-17 | 2009-09-16 | ヒューマン ジノーム サイエンシーズ, インコーポレイテッド | 死ドメイン含有レセプター5 |
| US20100152426A1 (en) * | 1997-05-15 | 2010-06-17 | Ashkenazi Avi J | Apo-2 receptor fusion proteins |
| US6342369B1 (en) * | 1997-05-15 | 2002-01-29 | Genentech, Inc. | Apo-2-receptor |
| ES2293682T5 (es) * | 1997-05-15 | 2011-11-17 | Genentech, Inc. | Anticuerpo anti-apo2. |
| WO1999011791A2 (en) * | 1997-09-05 | 1999-03-11 | University Of Washington | Tumor necrosis factor family receptors and ligands, encoding nucleic acids and related binding agents |
| CA2301173C (en) * | 1997-09-12 | 2015-04-14 | Biogen, Inc. | Cysteine rich receptors-train |
| WO2001060397A1 (en) | 2000-02-16 | 2001-08-23 | Genentech, Inc. | Uses of agonists and antagonists to modulate activity of tnf-related molecules |
| ATE443723T1 (de) * | 1998-06-12 | 2009-10-15 | Genentech Inc | Monoklonale antikörper, kreuz-reaktive antikörper und deren produktionsverfahren |
| AU3501700A (en) | 1999-02-26 | 2000-09-14 | Human Genome Sciences, Inc. | Human endokine alpha and methods of use |
| JP2002543151A (ja) * | 1999-05-04 | 2002-12-17 | ヒューマン ジノーム サイエンシーズ, インコーポレイテッド | 死ドメイン含有レセプター5 |
| EP1212413A1 (de) * | 1999-08-25 | 2002-06-12 | Genome Therapeutics Corporation | Eine transmembranfalle zur isolierung von membrangebundenen proteinen |
| MXPA02007787A (es) * | 2000-02-11 | 2004-09-10 | Inst Genetics Llc | Moleculas trade y uso relacionado con las mismas. |
| JP2003531588A (ja) | 2000-04-11 | 2003-10-28 | ジェネンテック・インコーポレーテッド | 多価抗体とその用途 |
| US7476383B2 (en) | 2000-05-02 | 2009-01-13 | The Uab Research Foundation | Antibody selective for DR4 and uses thereof |
| US7279160B2 (en) | 2000-05-02 | 2007-10-09 | The Uab Research Foundation | Combinations of DR5 antibodies and other therapeutic agents |
| TWI318983B (en) | 2000-05-02 | 2010-01-01 | Uab Research Foundation | An antibody selective for a tumor necrosis factor-related apoptosis-inducing ligand receptor and uses thereof |
| EP2431054A3 (de) | 2000-06-15 | 2013-03-06 | Human Genome Sciences, Inc. | Menschlicher Tumornekrosefaktor Delta und Ypsilon |
| PT2281843T (pt) | 2000-06-16 | 2017-01-02 | Human Genome Sciences Inc | Anticorpos que se ligam imunoespecificamente a blys |
| DE60136816D1 (de) | 2000-07-27 | 2009-01-15 | Genentech Inc | Sequentielle verabreichung von cpt-11 und apo-2l polypeptid |
| US20060062786A1 (en) * | 2000-11-08 | 2006-03-23 | Human Genome Sciences, Inc. | Antibodies that immunospecifically bind to TRAIL receptors |
| US20030228309A1 (en) * | 2000-11-08 | 2003-12-11 | Theodora Salcedo | Antibodies that immunospecifically bind to TRAIL receptors |
| US7115717B2 (en) | 2001-05-18 | 2006-10-03 | Kirin Beer Kabushiki Kaisha | Anti-TRAIL-R antibodies |
| US7361341B2 (en) | 2001-05-25 | 2008-04-22 | Human Genome Sciences, Inc. | Methods of treating cancer using antibodies that immunospecifically bind to trail receptors |
| US7348003B2 (en) | 2001-05-25 | 2008-03-25 | Human Genome Sciences, Inc. | Methods of treating cancer using antibodies that immunospecifically bind to TRAIL receptors |
| US20050129616A1 (en) * | 2001-05-25 | 2005-06-16 | Human Genome Sciences, Inc. | Antibodies that immunospecifically bind to TRAIL receptors |
| US7064189B2 (en) | 2001-05-25 | 2006-06-20 | Human Genome Sciences, Inc. | Antibodies that immunospecifically bind to trail receptors |
| US20090226429A1 (en) * | 2001-05-25 | 2009-09-10 | Human Genome Sciences, Inc. | Antibodies That Immunospecifically Bind to TRAIL Receptors |
| US20050214209A1 (en) * | 2001-05-25 | 2005-09-29 | Human Genome Sciences, Inc. | Antibodies that immunospecifically bind to TRAIL receptors |
| EP1409544B1 (de) | 2001-07-03 | 2009-06-17 | Genentech, Inc. | Humane dr4-antikörper und deren anwendungen |
| WO2003011318A1 (en) * | 2001-08-01 | 2003-02-13 | Genset S.A. | Agonists and antagonists of famoset for use in the treatment of metabolic disorders |
| EP1501866A4 (de) | 2001-10-02 | 2006-02-08 | Genentech Inc | Varianten des liganden apo-2 und verwendungen davon |
| JPWO2003038087A1 (ja) | 2001-10-04 | 2005-02-24 | 関西ティー・エル・オー株式会社 | DR5遺伝子のプロモーターおよびSiah−1遺伝子のプロモーター |
| EP1450847B1 (de) | 2001-11-13 | 2010-09-29 | Genentech, Inc. | Zusammensetzungen basierend auf APO2-Ligand/ TRAIL und ihre Verwendung |
| US7741285B2 (en) | 2001-11-13 | 2010-06-22 | Genentech, Inc. | APO-2 ligand/trail formulations |
| US7842668B1 (en) | 2001-11-13 | 2010-11-30 | Genentech, Inc. | Apo-2 ligand/trail formulations |
| AU2002361784A1 (en) * | 2001-12-20 | 2003-07-09 | Human Genome Sciences, Inc. | Antibodies that immunospecifically bind to trail receptors |
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| EP2500032A1 (de) | 2002-06-24 | 2012-09-19 | Genentech, Inc. | APO-2-Liganden-/Trailvarianten und Verwendungen dafür |
| KR20060132006A (ko) | 2004-03-23 | 2006-12-20 | 비오겐 아이덱 엠에이 아이엔씨. | 수용체 커플링제 및 이의 치료적 용도 |
| MX2007001469A (es) | 2004-08-06 | 2007-03-26 | Genentech Inc | Ensayos y metodos que utilizan biomarcadores. |
| CN101061238B (zh) * | 2004-08-06 | 2013-11-20 | 健泰科生物技术公司 | 使用生物标志的测定法和方法 |
| JP2008513367A (ja) * | 2004-09-08 | 2008-05-01 | ジェネンテック・インコーポレーテッド | デスレセプターリガンド及びcd20抗体の使用方法 |
| US20090175854A1 (en) * | 2004-09-08 | 2009-07-09 | Genentech, Inc. | Methods of using death receptor ligands and CD20 antibodies |
| JO3000B1 (ar) * | 2004-10-20 | 2016-09-05 | Genentech Inc | مركبات أجسام مضادة . |
| JP5562521B2 (ja) | 2005-02-02 | 2014-07-30 | ザ ユーエービー リサーチ ファンデーション | アポトーシス誘導デスレセプターアゴニストに対する抵抗性を低減することに関する薬剤及び方法 |
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| CN101287990B (zh) | 2005-08-16 | 2012-07-04 | 健泰科生物技术公司 | 通过检测细胞/组织中galnac-t14的表达判定对apo2l/trail的凋亡敏感性 |
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| WO2007142667A2 (en) | 2005-10-13 | 2007-12-13 | Human Genome Sciences, Inc. | Treatment of patients with autoantibody positive disease |
| ES2618543T3 (es) | 2005-11-23 | 2017-06-21 | Genentech, Inc. | Métodos y composiciones relacionados con ensayos de linfocitos B |
| JP2012504969A (ja) | 2008-10-10 | 2012-03-01 | アナフォア インコーポレイテッド | Trail−r1及びtrail−r2に結合するポリペプチド |
| US8790663B2 (en) | 2009-04-03 | 2014-07-29 | Institute Of Basic Medical Sciences, Chinese Academy Of Medical Sciences | Antigenic determinants of human death receptor DR5 |
| US8906231B2 (en) | 2009-09-10 | 2014-12-09 | Lonza Biologics Plc | Method and system for polypeptide purification |
| CA2780130A1 (en) | 2009-11-05 | 2011-05-12 | The Uab Research Foundation | Treating basal-like genotype cancers |
| US8703712B2 (en) | 2010-03-18 | 2014-04-22 | The Uab Research Foundation | Targeting cancer stem cells with DR5 agonists |
| PH12013500845A1 (en) | 2010-10-29 | 2013-06-24 | Daiichi Sankyo Co Ltd | Novel anti-dr5 antibody |
| SG191716A1 (en) | 2010-11-19 | 2013-08-30 | Toshio Imai | Neutralizing anti-ccl20 antibodies |
| CA2828405A1 (en) | 2011-02-28 | 2012-09-07 | Istituto Di Ricovero E Cura A Carattere Scientifico Materno-Infantile Bu Rlo Garofolo - Ospedale Di Alta Specializzazione E Di Rilievo Nazionale | Apoptosis-inducing molecules and uses therefor |
| EP2704735A1 (de) | 2011-05-03 | 2014-03-12 | Genentech, Inc. | Vaskuläre disruptoren und ihre verwendung |
| WO2014159562A1 (en) | 2013-03-14 | 2014-10-02 | Bristol-Myers Squibb Company | Combination of dr5 agonist and anti-pd-1 antagonist and methods of use |
| RU2679295C2 (ru) | 2013-03-22 | 2019-02-06 | Конинклейке Филипс Н.В. | Неинвазивное устройство для лечения кожи лазерным светом |
| CN104693308B (zh) * | 2013-12-05 | 2020-08-04 | 同济大学 | 感受胞内pH变化的Smad5蛋白及其应用 |
| EP3323428A1 (de) | 2016-11-17 | 2018-05-23 | CNRS Centre National de la Recherche Scientifique | Selektive c-flip-hemmer als antikrebsmittel |
| CN108997503B (zh) * | 2017-06-06 | 2021-07-23 | 深圳市中科艾深医药有限公司 | 人sDR5-Fc重组融合蛋白及其作为制备治疗生殖系统炎症的药物中的应用 |
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| EP4257132A1 (de) | 2022-04-08 | 2023-10-11 | iOmx Therapeutics AG | Sik3-inhibitoren zum behandeln von krankheiten, die gegen death-rezeptor -signaltransduktion resistent sind |
| WO2024175554A1 (en) | 2023-02-21 | 2024-08-29 | Institut Curie | Trail agonists for use in the treatment of cancer in patients having an activating alteration of fgfr3 |
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|---|---|---|---|---|
| US4002531A (en) * | 1976-01-22 | 1977-01-11 | Pierce Chemical Company | Modifying enzymes with polyethylene glycol and product produced thereby |
| US5807715A (en) * | 1984-08-27 | 1998-09-15 | The Board Of Trustees Of The Leland Stanford Junior University | Methods and transformed mammalian lymphocyte cells for producing functional antigen-binding protein including chimeric immunoglobulin |
| US4946778A (en) * | 1987-09-21 | 1990-08-07 | Genex Corporation | Single polypeptide chain binding molecules |
| US5530101A (en) * | 1988-12-28 | 1996-06-25 | Protein Design Labs, Inc. | Humanized immunoglobulins |
| GB8928874D0 (en) * | 1989-12-21 | 1990-02-28 | Celltech Ltd | Humanised antibodies |
| US5349053A (en) * | 1990-06-01 | 1994-09-20 | Protein Design Labs, Inc. | Chimeric ligand/immunoglobulin molecules and their uses |
| CA2067031C (en) * | 1991-04-26 | 2003-02-18 | Shigekazu Nagata | Dna coding for human cell surface antigen |
| IL99120A0 (en) * | 1991-08-07 | 1992-07-15 | Yeda Res & Dev | Multimers of the soluble forms of tnf receptors,their preparation and pharmaceutical compositions containing them |
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| TWI318983B (en) | 2000-05-02 | 2010-01-01 | Uab Research Foundation | An antibody selective for a tumor necrosis factor-related apoptosis-inducing ligand receptor and uses thereof |
-
1998
- 1998-03-17 JP JP54079098A patent/JP4330180B2/ja not_active Expired - Fee Related
- 1998-03-17 CN CNA2004100949179A patent/CN1624128A/zh active Pending
- 1998-03-17 DK DK98912966T patent/DK0970213T3/da active
- 1998-03-17 NZ NZ337795A patent/NZ337795A/en not_active IP Right Cessation
- 1998-03-17 AU AU67635/98A patent/AU747635B2/en not_active Withdrawn - After Issue
- 1998-03-17 US US09/042,583 patent/US7803615B1/en not_active Expired - Fee Related
- 1998-03-17 PT PT98912966T patent/PT970213E/pt unknown
- 1998-03-17 EP EP98912966A patent/EP0970213B1/de not_active Revoked
- 1998-03-17 KR KR10-1999-7008466A patent/KR100527638B1/ko not_active Expired - Fee Related
- 1998-03-17 DE DE69836956T patent/DE69836956T2/de not_active Revoked
- 1998-03-17 NZ NZ508381A patent/NZ508381A/xx not_active IP Right Cessation
- 1998-03-17 ES ES98912966T patent/ES2281126T3/es not_active Expired - Lifetime
- 1998-03-17 AT AT98912966T patent/ATE352618T1/de active
- 1998-03-17 CN CNB988045370A patent/CN1184315C/zh not_active Expired - Lifetime
- 1998-03-17 WO PCT/US1998/005377 patent/WO1998041629A2/en not_active Ceased
- 1998-03-17 CA CA002644454A patent/CA2644454A1/en not_active Abandoned
- 1998-03-17 CA CA002285040A patent/CA2285040C/en not_active Expired - Lifetime
-
2001
- 2001-12-07 US US10/005,842 patent/US20020098550A1/en not_active Abandoned
-
2007
- 2007-10-03 JP JP2007260427A patent/JP2008081503A/ja not_active Withdrawn
Also Published As
| Publication number | Publication date |
|---|---|
| WO1998041629A3 (en) | 1998-10-29 |
| DK0970213T3 (da) | 2007-05-21 |
| JP2001520513A (ja) | 2001-10-30 |
| US7803615B1 (en) | 2010-09-28 |
| AU6763598A (en) | 1998-10-12 |
| CA2285040A1 (en) | 1998-09-24 |
| CN1275162A (zh) | 2000-11-29 |
| KR20000076364A (ko) | 2000-12-26 |
| KR100527638B1 (ko) | 2005-11-23 |
| AU747635B2 (en) | 2002-05-16 |
| CN1184315C (zh) | 2005-01-12 |
| JP4330180B2 (ja) | 2009-09-16 |
| PT970213E (pt) | 2007-04-30 |
| WO1998041629A2 (en) | 1998-09-24 |
| EP0970213B1 (de) | 2007-01-24 |
| NZ337795A (en) | 2001-06-29 |
| JP2008081503A (ja) | 2008-04-10 |
| US20020098550A1 (en) | 2002-07-25 |
| CA2644454A1 (en) | 1998-09-24 |
| DE69836956T2 (de) | 2007-10-31 |
| NZ508381A (en) | 2002-09-27 |
| CA2285040C (en) | 2009-01-27 |
| CN1624128A (zh) | 2005-06-08 |
| DE69836956D1 (de) | 2007-03-15 |
| ES2281126T3 (es) | 2007-09-16 |
| HK1025352A1 (en) | 2000-11-10 |
| EP0970213A2 (de) | 2000-01-12 |
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