ATE311907T1 - Anwendung von komplexen von kationischen liposomen und polydeoxyribonukleotiden wie arzneimitteln - Google Patents
Anwendung von komplexen von kationischen liposomen und polydeoxyribonukleotiden wie arzneimittelnInfo
- Publication number
- ATE311907T1 ATE311907T1 AT99111118T AT99111118T ATE311907T1 AT E311907 T1 ATE311907 T1 AT E311907T1 AT 99111118 T AT99111118 T AT 99111118T AT 99111118 T AT99111118 T AT 99111118T AT E311907 T1 ATE311907 T1 AT E311907T1
- Authority
- AT
- Austria
- Prior art keywords
- complexes
- polydeoxyribonucleotides
- cationic liposomes
- drugs
- application
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/69—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit
- A61K47/6905—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit the form being a colloid or an emulsion
- A61K47/6911—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit the form being a colloid or an emulsion the form being a liposome
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Dispersion Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Epidemiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Hematology (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Diabetes (AREA)
- Cardiology (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Saccharide Compounds (AREA)
Applications Claiming Priority (6)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP99111118A EP1059092B1 (de) | 1999-06-08 | 1999-06-08 | Anwendung von Komplexen von kationischen Liposomen und Polydeoxyribonukleotiden wie Arzneimitteln |
| US09/330,215 US6767554B2 (en) | 1999-06-08 | 1999-06-11 | Use of complexes among cationic liposomes and polydeoxyribonucleotides and medicaments |
| AU35010/99A AU776014B2 (en) | 1999-06-11 | 1999-06-11 | Use of complexes among cationic liposomes and polydeoxyribonucleotides as medicaments |
| CA002274419A CA2274419A1 (en) | 1999-06-08 | 1999-06-11 | Use of complexes among cationic liposomes and polydeoxyribonucleotides as medicaments |
| KR1019990021947A KR100676492B1 (ko) | 1999-06-08 | 1999-06-12 | 양이온성 리포솜 및 폴리데옥시리보누클레오티드 사이의 복합체의 약제로서의 용도 |
| JP16700999A JP4598908B2 (ja) | 1999-06-08 | 1999-06-14 | カチオン性リポソームとポリデオキシリボヌクレオチドとの複合体 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE311907T1 true ATE311907T1 (de) | 2005-12-15 |
Family
ID=32330163
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT99111118T ATE311907T1 (de) | 1999-06-08 | 1999-06-08 | Anwendung von komplexen von kationischen liposomen und polydeoxyribonukleotiden wie arzneimitteln |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US6767554B2 (de) |
| EP (1) | EP1059092B1 (de) |
| JP (1) | JP4598908B2 (de) |
| KR (1) | KR100676492B1 (de) |
| AT (1) | ATE311907T1 (de) |
| CA (1) | CA2274419A1 (de) |
| DE (1) | DE69928778T2 (de) |
| DK (1) | DK1059092T3 (de) |
| ES (1) | ES2251134T3 (de) |
Families Citing this family (28)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2002232379B2 (en) | 2000-10-12 | 2006-07-13 | Rutgers, The State University Of New Jersey | Oligonucleotide - facilitated coalescence |
| EP1530465B2 (de) | 2002-06-26 | 2015-12-16 | MediGene AG | Herstellung einer kationisch liposomalen zubereitung, einen lipophilen wirkstoff enthaltend |
| JP2006193461A (ja) * | 2005-01-13 | 2006-07-27 | Pola Chem Ind Inc | 毛髪用の洗浄料 |
| ITMI20051303A1 (it) * | 2005-07-08 | 2007-01-09 | Inxel S R L | Metodo per la produzione di vernici in polvere termoindurenti particolarmente per l'applicazione mediante impianti elettrostatici |
| EP1872787A1 (de) * | 2006-06-27 | 2008-01-02 | Gentium S.p.A. | Verwendung von Defibrotide als Heparanasehemmer |
| WO2008093848A1 (ja) * | 2007-02-02 | 2008-08-07 | Sunstar Inc. | ホスファチジルコリンを含有する炎症マーカー低減組成物 |
| EP2103689A1 (de) * | 2008-03-19 | 2009-09-23 | Gentium S.p.A. | Synthetische Phosphodiester-Oligonukleotide und deren therapeutische Verwendungen |
| US20100279353A1 (en) * | 2009-04-30 | 2010-11-04 | Shiu Nan Chen | Process of producing fibrinolytic enzyme from mushroom |
| JP5142295B2 (ja) * | 2009-05-08 | 2013-02-13 | 独立行政法人農業・食品産業技術総合研究機構 | ベシクル及びその製法 |
| WO2010135714A2 (en) | 2009-05-22 | 2010-11-25 | The Methodist Hospital Research Institute | Methods for modulating adipocyte expression using microrna compositions |
| AU2010363814B2 (en) | 2010-11-12 | 2016-05-19 | Gentium S.R.L. | Defibrotide for use in prophylaxis and/or treatment of Graft versus Host Disease (GVHD). |
| GB201204632D0 (en) * | 2012-03-16 | 2012-05-02 | Univ Belfast | Delivery system |
| CN110079580B (zh) | 2012-06-22 | 2022-12-06 | 真蒂奥姆责任有限公司 | 用于测定去纤维蛋白多核苷酸的生物活性的基于优球蛋白的方法 |
| US11086970B2 (en) | 2013-03-13 | 2021-08-10 | Blue Belt Technologies, Inc. | Systems and methods for using generic anatomy models in surgical planning |
| KR101534276B1 (ko) * | 2014-07-18 | 2015-07-07 | 주식회사 에스씨301테라피 | 지방 이식 수술 후 지방세포 성장 및 생착 증진을 위한 조성물 |
| EP3026122A1 (de) | 2014-11-27 | 2016-06-01 | Gentium S.p.A. | Zellenbasiertes Verfahren zur Bestimmung der Wirksamkeit von Defibrotid |
| JP2020530004A (ja) | 2017-08-03 | 2020-10-15 | ジャズ ファーマシューティカルズ アイルランド リミテッド | 核酸を高濃度で含む製剤 |
| WO2019188867A1 (ja) | 2018-03-27 | 2019-10-03 | 日油株式会社 | 細胞内動態を改善した新規カチオン性脂質 |
| CN112236149A (zh) | 2018-04-12 | 2021-01-15 | 贾兹制药公司 | 用于预防和治疗细胞因子释放综合征和与免疫耗竭相关的神经毒性的去纤苷 |
| KR102144615B1 (ko) * | 2018-08-09 | 2020-08-13 | 장건주 | 폴리데옥시리보뉴클레오타이드를 포함하는 마이셀, 약물 전달체 및 이의 제조방법 |
| KR102132478B1 (ko) * | 2018-11-15 | 2020-07-10 | (주)진우바이오 | 히알루론산-폴리데옥시리보뉴클레오타이드 복합체와 이를 활용한 필름 및 이의 제조방법 |
| WO2020118165A1 (en) | 2018-12-07 | 2020-06-11 | Jazz Pharmaceuticals Ireland Limited | Subcutaneous delivery of high concentration formulations |
| WO2021060440A1 (ja) | 2019-09-26 | 2021-04-01 | 日油株式会社 | 脂質ナノ粒子の凍結乾燥組成物 |
| EP4110287A1 (de) | 2020-02-28 | 2023-01-04 | Jazz Pharmaceuticals Ireland Limited | Abgabe von niedrigviskosen formulierungen |
| TW202308659A (zh) | 2021-05-06 | 2023-03-01 | 愛爾蘭商爵士製藥愛爾蘭有限責任公司 | 用於急性呼吸窘迫症候群之治療及預防的去纖維蛋白多核苷酸 |
| KR20240070403A (ko) * | 2022-11-14 | 2024-05-21 | 주식회사 스템온 | 폴리데옥시리보뉴클레오티드를 포함하는 엑소좀, 이를 포함하는 조성물 및 이의 제조방법 |
| CN115737470B (zh) * | 2022-11-25 | 2024-09-10 | 润辉生物技术（威海）有限公司 | 一种肌肽-pdrn复合物及其制备方法和应用 |
| CN115836982B (zh) * | 2022-12-30 | 2024-02-06 | 南京乐韬生物科技有限公司 | 一种含pdrn的纳米乳液及其制备方法 |
Family Cites Families (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IT1043823B (it) | 1970-11-03 | 1980-02-29 | Prephar | Procedimento per l estrazione di acidi nucleici da organi animali |
| DE3017154A1 (de) | 1980-05-05 | 1981-11-12 | Hoechst Ag, 6000 Frankfurt | Verfahren zur herstellung von 2-chlor-1,1,1,2,3,3,3,-heptafluor-propan |
| HU192909B (en) * | 1985-01-17 | 1987-07-28 | Chinoin Gyogyszer Es Vegyeszet | Process for producing interfuranylene-prostacycline derivatives |
| IT1190313B (it) | 1986-04-17 | 1988-02-16 | Crinos Industria Farmaco | Procedimento per l'ottenimento di polidesossiribonucleotidi chimicamente definiti e riproducibili e prodotto farmacologicamente attivo risultante |
| WO1990003795A1 (en) * | 1988-10-05 | 1990-04-19 | Vestar, Inc. | Method of making liposomes with improved stability during drying |
| EP0462145B1 (de) * | 1989-03-07 | 1994-04-27 | Genentech, Inc. | Kovalente konjugate von lipiden und oligonukleotiden |
| EP0451791A2 (de) * | 1990-04-12 | 1991-10-16 | Hoechst Aktiengesellschaft | Langwirksame Liposomenpräparate von Peptidarzneistoffen und Verfahren zu ihrer Herstellung |
| DE59208629D1 (de) | 1991-11-01 | 1997-07-24 | Solvay | Verfahren zur Herstellung von 1,1,1,2,3,3,3-Heptafluorpropan (R 227) |
| IT1252174B (it) * | 1991-12-09 | 1995-06-05 | Crinos Industria Farmaco | Oligodesossimibonucleotidi ad attivita' antiischemica e procedimenti per il loro ottenimento |
| EP0562509B1 (de) | 1992-03-26 | 1996-08-21 | Hoechst Aktiengesellschaft | Verfahren zur Reaktivierung eines bei der Herstellung von 1,1,1,2,3,3,3-Heptafluorpropan (R 227) eingesetzten Aktivkohle-Katalysators |
| US5395619A (en) * | 1993-03-03 | 1995-03-07 | Liposome Technology, Inc. | Lipid-polymer conjugates and liposomes |
| DE4323054A1 (de) | 1993-07-14 | 1995-01-19 | Hoechst Ag | Verfahren zur Herstellung von 2-H-Heptafluorpropan |
| US6071890A (en) * | 1994-12-09 | 2000-06-06 | Genzyme Corporation | Organ-specific targeting of cationic amphiphile/DNA complexes for gene therapy |
| US5908777A (en) * | 1995-06-23 | 1999-06-01 | University Of Pittsburgh | Lipidic vector for nucleic acid delivery |
| ATE247971T1 (de) * | 1995-08-01 | 2003-09-15 | Novartis Erfind Verwalt Gmbh | Liposomale oligonukleotidzusammensetzungen |
| US5837283A (en) * | 1997-03-12 | 1998-11-17 | The Regents Of The University Of California | Cationic lipid compositions targeting angiogenic endothelial cells |
-
1999
- 1999-06-08 AT AT99111118T patent/ATE311907T1/de active
- 1999-06-08 EP EP99111118A patent/EP1059092B1/de not_active Expired - Lifetime
- 1999-06-08 DE DE69928778T patent/DE69928778T2/de not_active Expired - Lifetime
- 1999-06-08 ES ES99111118T patent/ES2251134T3/es not_active Expired - Lifetime
- 1999-06-08 DK DK99111118T patent/DK1059092T3/da active
- 1999-06-11 US US09/330,215 patent/US6767554B2/en not_active Expired - Lifetime
- 1999-06-11 CA CA002274419A patent/CA2274419A1/en not_active Abandoned
- 1999-06-12 KR KR1019990021947A patent/KR100676492B1/ko not_active Expired - Fee Related
- 1999-06-14 JP JP16700999A patent/JP4598908B2/ja not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| DK1059092T3 (da) | 2006-03-27 |
| EP1059092B1 (de) | 2005-12-07 |
| US20020142029A1 (en) | 2002-10-03 |
| JP4598908B2 (ja) | 2010-12-15 |
| ES2251134T3 (es) | 2006-04-16 |
| DE69928778D1 (de) | 2006-01-12 |
| KR20010002244A (ko) | 2001-01-15 |
| KR100676492B1 (ko) | 2007-01-30 |
| JP2001002565A (ja) | 2001-01-09 |
| DE69928778T2 (de) | 2006-07-06 |
| EP1059092A1 (de) | 2000-12-13 |
| US6767554B2 (en) | 2004-07-27 |
| CA2274419A1 (en) | 2000-12-11 |
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| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification |
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