ATE312200T1 - Einzelschicht und elektrode zur feststellung von markierten molekülen und verfahren zu deren verwendung - Google Patents
Einzelschicht und elektrode zur feststellung von markierten molekülen und verfahren zu deren verwendungInfo
- Publication number
- ATE312200T1 ATE312200T1 AT00913366T AT00913366T ATE312200T1 AT E312200 T1 ATE312200 T1 AT E312200T1 AT 00913366 T AT00913366 T AT 00913366T AT 00913366 T AT00913366 T AT 00913366T AT E312200 T1 ATE312200 T1 AT E312200T1
- Authority
- AT
- Austria
- Prior art keywords
- nucleic acid
- electrode
- detecting
- oxidation
- reduction reaction
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 2
- 239000002356 single layer Substances 0.000 title 1
- 108020004707 nucleic acids Proteins 0.000 abstract 7
- 150000007523 nucleic acids Chemical class 0.000 abstract 7
- 102000039446 nucleic acids Human genes 0.000 abstract 7
- 238000006479 redox reaction Methods 0.000 abstract 3
- 239000002094 self assembled monolayer Substances 0.000 abstract 2
- 239000013545 self-assembled monolayer Substances 0.000 abstract 2
- 108020005187 Oligonucleotide Probes Proteins 0.000 abstract 1
- 239000000427 antigen Substances 0.000 abstract 1
- 102000036639 antigens Human genes 0.000 abstract 1
- 108091007433 antigens Proteins 0.000 abstract 1
- 230000015572 biosynthetic process Effects 0.000 abstract 1
- 230000003993 interaction Effects 0.000 abstract 1
- 239000003446 ligand Substances 0.000 abstract 1
- 239000002751 oligonucleotide probe Substances 0.000 abstract 1
- 230000001590 oxidative effect Effects 0.000 abstract 1
- 229910052723 transition metal Inorganic materials 0.000 abstract 1
- 150000003624 transition metals Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
- C12Q1/6816—Hybridisation assays characterised by the detection means
- C12Q1/6825—Nucleic acid detection involving sensors
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B82—NANOTECHNOLOGY
- B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
- B82Y30/00—Nanotechnology for materials or surface science, e.g. nanocomposites
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B82—NANOTECHNOLOGY
- B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
- B82Y15/00—Nanotechnology for interacting, sensing or actuating, e.g. quantum dots as markers in protein assays or molecular motors
Landscapes
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Nanotechnology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Physics & Mathematics (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Analytical Chemistry (AREA)
- Crystallography & Structural Chemistry (AREA)
- Biotechnology (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Immunology (AREA)
- Materials Engineering (AREA)
- General Physics & Mathematics (AREA)
- Condensed Matter Physics & Semiconductors (AREA)
- Composite Materials (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
- Investigating Or Analyzing Materials By The Use Of Electric Means (AREA)
- Force Measurement Appropriate To Specific Purposes (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US09/296,929 US6127127A (en) | 1995-06-27 | 1999-04-22 | Monolayer and electrode for detecting a label-bearing target and method of use thereof |
| PCT/US2000/002976 WO2000065099A1 (en) | 1999-04-22 | 2000-02-04 | Monolayer and electrode for detecting a label-bearing target and method of use thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE312200T1 true ATE312200T1 (de) | 2005-12-15 |
Family
ID=23144136
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT00913366T ATE312200T1 (de) | 1999-04-22 | 2000-02-04 | Einzelschicht und elektrode zur feststellung von markierten molekülen und verfahren zu deren verwendung |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US6127127A (de) |
| EP (1) | EP1185692B1 (de) |
| JP (1) | JP2002542794A (de) |
| KR (1) | KR20020008157A (de) |
| CN (1) | CN1347460A (de) |
| AT (1) | ATE312200T1 (de) |
| AU (1) | AU781085B2 (de) |
| CA (1) | CA2367594A1 (de) |
| DE (1) | DE60024618D1 (de) |
| HK (1) | HK1045178B (de) |
| NO (1) | NO20014882L (de) |
| NZ (1) | NZ514682A (de) |
| WO (1) | WO2000065099A1 (de) |
Families Citing this family (52)
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|---|---|---|---|---|
| US6207369B1 (en) * | 1995-03-10 | 2001-03-27 | Meso Scale Technologies, Llc | Multi-array, multi-specific electrochemiluminescence testing |
| US6346387B1 (en) | 1995-06-27 | 2002-02-12 | Xanthon, Inc. | Detection of binding reactions using labels detected by mediated catalytic electrochemistry |
| US7815963B2 (en) * | 1996-10-17 | 2010-10-19 | The Trustees Of Princeton University | Enhanced bonding layers on titanium materials |
| US6013459A (en) | 1997-06-12 | 2000-01-11 | Clinical Micro Sensors, Inc. | Detection of analytes using reorganization energy |
| US6833267B1 (en) * | 1998-12-30 | 2004-12-21 | Clinical Micro Sensors, Inc. | Tissue collection devices containing biosensors |
| US20020177135A1 (en) * | 1999-07-27 | 2002-11-28 | Doung Hau H. | Devices and methods for biochip multiplexing |
| US7348183B2 (en) * | 2000-10-16 | 2008-03-25 | Board Of Trustees Of The University Of Arkansas | Self-contained microelectrochemical bioassay platforms and methods |
| AU2002241803A1 (en) * | 2000-10-20 | 2002-06-18 | The Board Of Trustees Of The Leland Stanford Junior University | Transient electrical signal based methods and devices for characterizing molecular interaction and/or motion in a sample |
| US6632536B2 (en) * | 2000-12-28 | 2003-10-14 | International Business Machines Corporation | Self-assembled monolayer etch barrier for indium-tin-oxide useful in manufacturing thin film transistor-liquid crystal displays |
| DE10126798A1 (de) * | 2001-06-01 | 2002-12-19 | Nanotype Gmbh | Verfahren zur Bestimmung einer Probe |
| US20020182606A1 (en) * | 2001-06-04 | 2002-12-05 | Xanthon, Inc. | Detection of single nucleotide polymorphisms |
| CA2450109A1 (en) * | 2001-06-11 | 2003-05-22 | Genorx, Inc. | Electronic detection of biological molecules using thin layers |
| US6824974B2 (en) * | 2001-06-11 | 2004-11-30 | Genorx, Inc. | Electronic detection of biological molecules using thin layers |
| WO2003001889A2 (en) * | 2001-06-29 | 2003-01-09 | Meso Scale Technologies, Llc. | Assay plates reader systems and methods for luminescence test measurements |
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| US7202028B2 (en) * | 2001-09-24 | 2007-04-10 | The University Of North Carolina At Chapel Hill | Methods for the electrochemical detection of multiple target compounds |
| AU2004201425B2 (en) * | 2001-09-24 | 2007-06-28 | University Of North Carolina At Chapel Hill | Methods for the electrochemical detection of multiple target compounds |
| AU2002367807B2 (en) * | 2001-09-24 | 2007-06-28 | University Of North Carolina At Chapel Hill | Methods for the electrochemical detection of multiple target compounds |
| WO2003066817A2 (en) * | 2002-02-06 | 2003-08-14 | Amersham Biosciences Ab | Compositions and methods for rolling circle amplification |
| GB0205455D0 (en) | 2002-03-07 | 2002-04-24 | Molecular Sensing Plc | Nucleic acid probes, their synthesis and use |
| GB0211449D0 (en) * | 2002-05-17 | 2002-06-26 | Oxford Biosensors Ltd | Analyte measurement |
| AU2003260662A1 (en) * | 2002-12-11 | 2004-07-14 | Centre National De La Recherche Scientifique | Method for electronically detecting at least one specific interaction between probe molecules and target biomolecules |
| US20040180369A1 (en) * | 2003-01-16 | 2004-09-16 | North Carolina State University | Photothermal detection of nucleic acid hybridization |
| US7138121B2 (en) * | 2003-01-23 | 2006-11-21 | Spangler Brenda D | Biosensors utilizing dendrimer-immobilized ligands and there use thereof |
| KR100547015B1 (ko) * | 2003-05-23 | 2006-01-26 | 주식회사 올메디쿠스 | 일정한 크기 이상의 분석물질을 정량 분석하기 위한바이오센서 및 그 제조방법 |
| US20100000881A1 (en) * | 2003-10-30 | 2010-01-07 | North Carolina State University | Electrochemical detection of nucleic acid hybridization |
| WO2005042783A1 (en) * | 2003-10-30 | 2005-05-12 | North Carolina State University | Temperature-jump enhanced electrochemical detection of nucleic acid hybridization |
| US7981362B2 (en) * | 2003-11-04 | 2011-07-19 | Meso Scale Technologies, Llc | Modular assay plates, reader systems and methods for test measurements |
| US8048377B1 (en) | 2004-03-08 | 2011-11-01 | Hewlett-Packard Development Company, L.P. | Immobilizing chemical or biological sensing molecules on semi-conducting nanowires |
| US7462452B2 (en) * | 2004-04-30 | 2008-12-09 | Pacific Biosciences Of California, Inc. | Field-switch sequencing |
| US20060094024A1 (en) * | 2004-11-01 | 2006-05-04 | Pirrung Michael C | Electrochemical arrays |
| US20090203547A1 (en) * | 2005-02-18 | 2009-08-13 | Albert Banes | Gene and Cognate Protein Profiles and Methods to Determine Connective Tissue Markers in Normal and Pathologic Conditions |
| US20070235346A1 (en) * | 2006-04-11 | 2007-10-11 | Popovich Natasha D | System and methods for providing corrected analyte concentration measurements |
| US7909983B2 (en) * | 2006-05-04 | 2011-03-22 | Nipro Diagnostics, Inc. | System and methods for automatically recognizing a control solution |
| US8465926B2 (en) * | 2006-08-11 | 2013-06-18 | The Hong Kong University Of Science And Technology | Method and system for real time quantification and monitoring of nucleic acid amplification using electroconductive or electrochemically active labels |
| US20080131709A1 (en) * | 2006-09-28 | 2008-06-05 | Aculon Inc. | Composite structure with organophosphonate adherent layer and method of preparing |
| US8907061B2 (en) | 2008-01-11 | 2014-12-09 | Lawrence Livermore National Security, Llc. | Nanolipoprotein particles and related methods and systems for protein capture, solubilization, and/or purification |
| US20090203549A1 (en) * | 2008-02-07 | 2009-08-13 | Hoeprich Jr Paul D | Functionalized platform for arrays configured for optical detection of targets and related arrays, methods and systems |
| US9303273B2 (en) | 2008-05-09 | 2016-04-05 | Lawrence Livermore National Security, Llc | Nanolipoprotein particles comprising a natural rubber biosynthetic enzyme complex and related products, methods and systems |
| US10151037B2 (en) | 2009-01-12 | 2018-12-11 | Lawrence Livermore National Security, Llc | Electrochemical flow-cell for hydrogen production and nicotinamide dependent target reduction, and related methods and systems |
| US8906610B2 (en) | 2010-02-08 | 2014-12-09 | The Regents Of The University Of California | Using phylogenetic probes for quantification of stable isotope labeling and microbial community analysis |
| CA3177188A1 (en) | 2011-01-06 | 2012-07-12 | Meso Scale Technologies, Llc. | Assay cartridges for pcr analysis and methods of use thereof |
| US9644038B2 (en) | 2011-12-21 | 2017-05-09 | The Regents Of The University Of California | Apolipoprotein nanodiscs with telodendrimer |
| WO2017035326A1 (en) | 2015-08-25 | 2017-03-02 | Lawrence Livermore National Security, Llc | Stable nanolipoprotein particles and related compositions methods and systems |
| US11279749B2 (en) | 2015-09-11 | 2022-03-22 | Lawrence Livermore National Security, Llc | Synthetic apolipoproteins, and related compositions methods and systems for nanolipoprotein particles formation |
| KR101862198B1 (ko) * | 2016-09-30 | 2018-05-30 | (주)스파크바이오파마 | 2차원 겔 전기영동에서의 열 안정성 변화-기반 형광 차이를 이용한 표적 단백질의 규명 방법 |
| US12083223B2 (en) | 2017-05-02 | 2024-09-10 | Lawrence Livermore National Security, Llc | Nanolipoprotein particles and related compositions methods and systems for loading RNA |
| WO2018204421A2 (en) | 2017-05-02 | 2018-11-08 | Lawrence Livermore National Security, Llc | Momp telonanoparticles, and related compositions, methods and systems |
| WO2019075261A1 (en) * | 2017-10-11 | 2019-04-18 | Microvention, Inc. | PHOSPHONATES AND THEIR USES |
| CN116242814B (zh) * | 2023-04-14 | 2025-10-03 | 中国农业大学 | 一种联吡啶类化合物的荧光检测方法 |
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-
1999
- 1999-04-22 US US09/296,929 patent/US6127127A/en not_active Expired - Lifetime
-
2000
- 2000-02-04 AU AU34830/00A patent/AU781085B2/en not_active Ceased
- 2000-02-04 NZ NZ514682A patent/NZ514682A/en unknown
- 2000-02-04 HK HK02106722.0A patent/HK1045178B/en not_active IP Right Cessation
- 2000-02-04 CA CA002367594A patent/CA2367594A1/en not_active Abandoned
- 2000-02-04 AT AT00913366T patent/ATE312200T1/de not_active IP Right Cessation
- 2000-02-04 DE DE60024618T patent/DE60024618D1/de not_active Expired - Lifetime
- 2000-02-04 CN CN00806497A patent/CN1347460A/zh active Pending
- 2000-02-04 JP JP2000614433A patent/JP2002542794A/ja not_active Withdrawn
- 2000-02-04 KR KR1020017013429A patent/KR20020008157A/ko not_active Ceased
- 2000-02-04 WO PCT/US2000/002976 patent/WO2000065099A1/en not_active Ceased
- 2000-02-04 EP EP00913366A patent/EP1185692B1/de not_active Expired - Lifetime
-
2001
- 2001-10-08 NO NO20014882A patent/NO20014882L/no unknown
Also Published As
| Publication number | Publication date |
|---|---|
| KR20020008157A (ko) | 2002-01-29 |
| DE60024618D1 (de) | 2006-01-12 |
| HK1045178B (en) | 2006-08-11 |
| EP1185692A1 (de) | 2002-03-13 |
| JP2002542794A (ja) | 2002-12-17 |
| US6127127A (en) | 2000-10-03 |
| WO2000065099A1 (en) | 2000-11-02 |
| NO20014882L (no) | 2001-12-27 |
| NO20014882D0 (no) | 2001-10-08 |
| CN1347460A (zh) | 2002-05-01 |
| NZ514682A (en) | 2003-07-25 |
| HK1045178A1 (en) | 2002-11-15 |
| CA2367594A1 (en) | 2000-11-02 |
| AU3483000A (en) | 2000-11-10 |
| AU781085B2 (en) | 2005-05-05 |
| EP1185692B1 (de) | 2005-12-07 |
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