ATE312910T1 - Zusammensetzung stabiler, biotinylierter biomoleküle und verfahren - Google Patents

Zusammensetzung stabiler, biotinylierter biomoleküle und verfahren

Info

Publication number
ATE312910T1
ATE312910T1 AT96937005T AT96937005T ATE312910T1 AT E312910 T1 ATE312910 T1 AT E312910T1 AT 96937005 T AT96937005 T AT 96937005T AT 96937005 T AT96937005 T AT 96937005T AT E312910 T1 ATE312910 T1 AT E312910T1
Authority
AT
Austria
Prior art keywords
stable
biotinylated
composition
methods
compositions
Prior art date
Application number
AT96937005T
Other languages
English (en)
Inventor
Steven J Burton
James C Pearson
Peter A D Edwardson
Alan Menzies
Original Assignee
Bristol Myers Squibb Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bristol Myers Squibb Co filed Critical Bristol Myers Squibb Co
Application granted granted Critical
Publication of ATE312910T1 publication Critical patent/ATE312910T1/de

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54306—Solid-phase reaction mechanisms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2/00—Disinfection or sterilisation of materials or objects, in general; Accessories therefor
    • A61L2/02—Disinfection or sterilisation of materials or objects, in general; Accessories therefor using physical processes
    • A61L2/08—Radiation
    • A61L2/081—Gamma radiation
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/745—Blood coagulation or fibrinolysis factors
    • C07K14/75—Fibrinogen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2103/00—Materials or objects being the target of disinfection or sterilisation
    • A61L2103/05—Living organisms or biological materials

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Hematology (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Urology & Nephrology (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Organic Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Zoology (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Food Science & Technology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Analytical Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Toxicology (AREA)
  • Cell Biology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Epidemiology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Materials For Medical Uses (AREA)
AT96937005T 1995-11-09 1996-10-24 Zusammensetzung stabiler, biotinylierter biomoleküle und verfahren ATE312910T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/555,602 US6551794B1 (en) 1995-11-09 1995-11-09 Stable biotinylated biomolecule composition
PCT/US1996/017200 WO1997017435A1 (en) 1995-11-09 1996-10-24 Stable biotinylated biomolecule composition and methods

Publications (1)

Publication Number Publication Date
ATE312910T1 true ATE312910T1 (de) 2005-12-15

Family

ID=24217905

Family Applications (1)

Application Number Title Priority Date Filing Date
AT96937005T ATE312910T1 (de) 1995-11-09 1996-10-24 Zusammensetzung stabiler, biotinylierter biomoleküle und verfahren

Country Status (13)

Country Link
US (1) US6551794B1 (de)
EP (1) EP0865486B1 (de)
JP (2) JP2000514778A (de)
AT (1) ATE312910T1 (de)
AU (1) AU717383B2 (de)
BR (1) BR9611430A (de)
CA (1) CA2237357C (de)
DE (1) DE69635584T2 (de)
DK (1) DK0865486T3 (de)
ES (1) ES2252761T3 (de)
IL (1) IL124375A (de)
NZ (1) NZ321443A (de)
WO (1) WO1997017435A1 (de)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0868916A3 (de) * 1997-03-04 2004-09-15 Kabushiki Kaisha Hayashibara Seibutsu Kagaku Kenkyujo Reduktionshemmungsmittel für Aktiv-Sauerstoff entfernende Aktivität
CA2312476A1 (en) * 1997-12-09 1999-06-17 Bristol-Myers Squibb Company Fibrinogen-converting enzyme hybrids
US6187555B1 (en) 1998-04-16 2001-02-13 3M Innovative Properties Company Spores with increased sensitivity to sterilants using additives that bind to sterilant-sensitive sites
WO2001087357A2 (en) * 2000-05-17 2001-11-22 The American National Red Cross Gamma irradiation of protein-based pharmaceutical products
US6506365B1 (en) * 2000-09-25 2003-01-14 Baxter Aktiengesellschaft Fibrin/fibrinogen binding conjugate
US20030068416A1 (en) * 2001-09-24 2003-04-10 Wilson Burgess Method of lyophylization to reduce solvent content and enhance product recovery
US7319032B2 (en) * 2004-04-22 2008-01-15 Medtox Non-sugar sweeteners for use in test devices
EP1852443A1 (de) 2006-05-05 2007-11-07 Leukocare AG Biokompatible dreidimensionale Matrix für die Immobilisierung von biologischen Substanzen
EP2058335B1 (de) * 2007-11-07 2020-06-24 Leukocare Ag Biologisch verträgliche, dreidimensionale Matrix zur Immobilisierung von biologischen Substanzen
US20160252434A1 (en) * 2014-04-16 2016-09-01 General Electric Company Gamma sterilized dextran solutions and methods of use
US20150299657A1 (en) * 2014-04-16 2015-10-22 General Electric Company Gamma stabilized dextran solutions and methods of use
RU2678828C2 (ru) * 2012-05-14 2019-02-04 Тейдзин Лимитед Белковая композиция, устойчивая к стерилизации облучением
CN103446600B (zh) * 2012-05-31 2020-05-22 通用电气公司 为含有葡萄糖氧化酶的膜杀菌的方法和相应的生物传感器
US20180055958A1 (en) 2015-03-12 2018-03-01 Sanyo Chemical Industries, Ltd. Method for producing protein composition, and protein composition
KR102774917B1 (ko) * 2018-05-18 2025-03-04 퀴아젠 사이언시스, 엘엘씨 방사선 멸균 또는 보관 기간 동안 생물학적으로 활성인 분자를 보호하는 방법
CN112852666A (zh) * 2021-01-19 2021-05-28 新疆河润水业有限责任公司 一种微生物菌剂的制备方法及采用微生物菌剂制备的微生物肥料

Family Cites Families (23)

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Publication number Priority date Publication date Assignee Title
US3779706A (en) * 1971-10-04 1973-12-18 Energy Sciences Inc Process for bulk sterilization, minimizing chemical and physical damage
GB8331514D0 (en) 1983-11-25 1984-01-04 Janssen Pharmaceutica Nv Visualization method
JP2624470B2 (ja) 1984-10-02 1997-06-25 バイオジェン インコーポレイテッド ストレプトアビジン様ポリペプチドの製造
IL76234A0 (en) 1985-08-28 1986-01-31 Yeda Res & Dev New biotinylation reagents
US4806343A (en) * 1986-03-13 1989-02-21 University Of Southwestern Louisiana Cryogenic protectant for proteins
US4897346A (en) * 1986-07-15 1990-01-30 Beckman Instruments, Inc. Stabilized liquid enzyme composition for glucose determination
US4794082A (en) 1987-02-17 1988-12-27 Hoechst Celanese Corporation Biotinylating agents
US4709037A (en) 1987-02-17 1987-11-24 Hoechst Celanese Corporation Biotinylating agents
US4798795A (en) 1987-02-17 1989-01-17 Hoechst Celanese Corporation Biotinylating agents
JPS63246382A (ja) 1987-04-02 1988-10-13 Karupisu Shokuhin Kogyo Kk ビオチニル試薬及びそれを用いるビオチニル化法
US5043288A (en) 1988-06-20 1991-08-27 Motsenbocker Marvin A Immobilize molecular binding partners to contact activating supports
FR2638099B1 (fr) 1988-10-20 1991-01-25 Immunotech Sa Immunoadsorbant a faible taux de relargage et son procede d'obtention
US4897364A (en) 1989-02-27 1990-01-30 Motorola, Inc. Method for locos isolation using a framed oxidation mask and a polysilicon buffer layer
US5026785A (en) 1989-05-12 1991-06-25 The United States Of America As Represented By The Department Of Health And Human Services Avidin and streptavidin modified water-soluble polymers such as polyacrylamide, and the use thereof in the construction of soluble multivalent macromolecular conjugates
JPH05331071A (ja) * 1992-01-17 1993-12-14 Asahi Chem Ind Co Ltd カルシトニン遺伝子関連ペプチド類の凍結乾燥組成物および安定化法
US5306824A (en) 1992-04-15 1994-04-26 Georgia Tech Research Corporation Biotinylated isocoumarins
CN1091315A (zh) * 1992-10-08 1994-08-31 E·R·斯奎布父子公司 血纤维蛋白封闭剂组合物及其使用方法
JP3007785B2 (ja) * 1993-03-16 2000-02-07 旭化成工業株式会社 トロンボモジュリン組成物およびその変性防止方法
EP0731834B1 (de) 1993-12-03 2000-05-24 Buckman Laboratories International, Inc. Enzymstabilisierung durch blockcopolymere
JPH07194378A (ja) 1993-12-28 1995-08-01 Fuji Seito Kk トレハロースによる酵素の安定化法
US5556771A (en) 1995-02-10 1996-09-17 Gen-Probe Incorporated Stabilized compositions of reverse transcriptase and RNA polymerase for nucleic acid amplification
WO1997011183A1 (en) * 1995-04-11 1997-03-27 Trustees Of Boston University Streptavidin mutants
US5691152A (en) * 1995-11-09 1997-11-25 E. R. Squibb & Sons, Inc. Stable avidin composition

Also Published As

Publication number Publication date
ES2252761T3 (es) 2006-05-16
DE69635584D1 (de) 2006-01-19
IL124375A0 (en) 1998-12-06
DE69635584T2 (de) 2006-09-21
IL124375A (en) 2002-04-21
EP0865486A4 (de) 2002-06-26
JP2000514778A (ja) 2000-11-07
JP2007295936A (ja) 2007-11-15
DK0865486T3 (da) 2006-02-06
NZ321443A (en) 2000-01-28
EP0865486A1 (de) 1998-09-23
AU717383B2 (en) 2000-03-23
BR9611430A (pt) 1999-06-29
CA2237357C (en) 2002-07-30
WO1997017435A1 (en) 1997-05-15
EP0865486B1 (de) 2005-12-14
AU7477796A (en) 1997-05-29
US6551794B1 (en) 2003-04-22
CA2237357A1 (en) 1997-05-15

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