|
US6849708B1
(en)
|
1986-05-05 |
2005-02-01 |
The General Hospital Corporation |
Insulinotropic hormone and uses thereof
|
|
US5614492A
(en)
*
|
1986-05-05 |
1997-03-25 |
The General Hospital Corporation |
Insulinotropic hormone GLP-1 (7-36) and uses thereof
|
|
US7138486B2
(en)
|
1986-05-05 |
2006-11-21 |
The General Hospital Corporation |
Insulinotropic hormone derivatives and uses thereof
|
|
FR2686899B1
(fr)
|
1992-01-31 |
1995-09-01 |
Rhone Poulenc Rorer Sa |
Nouveaux polypeptides biologiquement actifs, leur preparation et compositions pharmaceutiques les contenant.
|
|
JPH0682743A
(ja)
*
|
1992-09-04 |
1994-03-25 |
Sony Corp |
強誘電性液晶組成物
|
|
US6284727B1
(en)
|
1993-04-07 |
2001-09-04 |
Scios, Inc. |
Prolonged delivery of peptides
|
|
EP0658568A1
(de)
*
|
1993-12-09 |
1995-06-21 |
Eli Lilly And Company |
Glucagon-ähnliche, insalinotrope Peptide, ihre Zusammensetzungen und ihre Herstellungsverfahren
|
|
US5705483A
(en)
*
|
1993-12-09 |
1998-01-06 |
Eli Lilly And Company |
Glucagon-like insulinotropic peptides, compositions and methods
|
|
GB9409496D0
(en)
|
1994-05-12 |
1994-06-29 |
London Health Ass |
Method for improving glycaemic control in diabetes
|
|
US5574008A
(en)
*
|
1994-08-30 |
1996-11-12 |
Eli Lilly And Company |
Biologically active fragments of glucagon-like insulinotropic peptide
|
|
US5512549A
(en)
*
|
1994-10-18 |
1996-04-30 |
Eli Lilly And Company |
Glucagon-like insulinotropic peptide analogs, compositions, and methods of use
|
|
AU4298596A
(en)
*
|
1994-12-23 |
1996-07-19 |
Novo Nordisk A/S |
Protracted glp-1 compositions
|
|
US6852690B1
(en)
|
1995-08-22 |
2005-02-08 |
Amylin Pharmaceuticals, Inc. |
Method and composition for enhanced parenteral nutrition
|
|
DE19530865A1
(de)
*
|
1995-08-22 |
1997-02-27 |
Michael Dr Med Nauck |
Wirkstoff sowie Mittel zur parenteralen Ernährung
|
|
US5766620A
(en)
*
|
1995-10-23 |
1998-06-16 |
Theratech, Inc. |
Buccal delivery of glucagon-like insulinotropic peptides
|
|
US5849322A
(en)
*
|
1995-10-23 |
1998-12-15 |
Theratech, Inc. |
Compositions and methods for buccal delivery of pharmaceutical agents
|
|
JP2001503963A
(ja)
*
|
1996-02-06 |
2001-03-27 |
イーライ・リリー・アンド・カンパニー |
糖尿病治療
|
|
CN1198100A
(zh)
*
|
1996-06-11 |
1998-11-04 |
佐纳根有限公司 |
聚氨基葡糖药物投递系统
|
|
US6458924B2
(en)
|
1996-08-30 |
2002-10-01 |
Novo Nordisk A/S |
Derivatives of GLP-1 analogs
|
|
US6006753A
(en)
*
|
1996-08-30 |
1999-12-28 |
Eli Lilly And Company |
Use of GLP-1 or analogs to abolish catabolic changes after surgery
|
|
US7235627B2
(en)
|
1996-08-30 |
2007-06-26 |
Novo Nordisk A/S |
Derivatives of GLP-1 analogs
|
|
CA2283834A1
(en)
*
|
1997-03-31 |
1998-10-08 |
James Arthur Hoffmann |
Glucagon-like peptide-1 analogs
|
|
DE69831421T2
(de)
*
|
1997-12-02 |
2006-06-22 |
Archimedes Development Ltd. |
Zusammensetzungen zur nasalen verabreichung
|
|
AU1617399A
(en)
*
|
1997-12-05 |
1999-06-28 |
Eli Lilly And Company |
Glp-1 formulations
|
|
US6380357B2
(en)
|
1997-12-16 |
2002-04-30 |
Eli Lilly And Company |
Glucagon-like peptide-1 crystals
|
|
ATE269103T1
(de)
|
1998-03-13 |
2004-07-15 |
Novo Nordisk As |
Stabilisierte wässerige glukagonlösungen enthaltend detergenzien
|
|
ATE445006T1
(de)
|
1998-08-10 |
2009-10-15 |
Us Gov Health & Human Serv |
Differenzierung von nicht-insulin in insulin- produzierende zellen durch glp-1 und exendin-4 und dessen verwendung
|
|
KR20010073033A
(ko)
*
|
1998-08-28 |
2001-07-31 |
피터 지. 스트링거 |
인슐리노트로픽 펩티드의 투여 방법
|
|
EP1666054A1
(de)
*
|
1998-08-28 |
2006-06-07 |
Eli Lilly & Company |
Methode zur Verabreichung von Peptiden mit insulinotroper Wirkung
|
|
US6924264B1
(en)
|
1999-04-30 |
2005-08-02 |
Amylin Pharmaceuticals, Inc. |
Modified exendins and exendin agonists
|
|
CN1372570A
(zh)
|
1999-04-30 |
2002-10-02 |
安米林药品公司 |
修饰的exendin和exendin激动剂
|
|
WO2001030373A1
(en)
*
|
1999-10-28 |
2001-05-03 |
Institut Neftekhimicheskogo Sinteza Imeni A.V.To Pchieva Rossiiskoi Akademii Nauk (Inkhs Ran) |
Polypeptide composition
|
|
EP1396499A3
(de)
*
|
2000-01-27 |
2004-12-29 |
Eli Lilly And Company |
Verfahren zur Lösung von Glucagon-ähnlichen Peptid-1 (GLP-1) Verbindungen
|
|
BR0107837A
(pt)
|
2000-01-27 |
2003-01-14 |
Lilly Co Eli |
Processo para solubilização de compostos peptìdeo 1 semelhantes a glucagon
|
|
AU2001228327A1
(en)
*
|
2000-01-31 |
2001-08-14 |
Novo-Nordisk A/S |
Crystallisation of a glp-1 analogue
|
|
US6844321B2
(en)
|
2000-01-31 |
2005-01-18 |
Novo Nordisk A/S |
Crystallization of a GLP-1 analogue
|
|
JP2003530838A
(ja)
|
2000-04-12 |
2003-10-21 |
ヒューマン ゲノム サイエンシズ インコーポレイテッド |
アルブミン融合タンパク質
|
|
ATE416784T1
(de)
|
2000-12-01 |
2008-12-15 |
Takeda Pharmaceutical |
Verfahren zur herstellung einer zubereitung mit einer bioaktiven substanz
|
|
AU2002228608A1
(en)
|
2000-12-13 |
2002-06-24 |
Eli Lilly And Company |
Amidated glucagon-like peptide-1
|
|
AU2002308706A1
(en)
|
2001-06-01 |
2002-12-16 |
Eli Lilly And Company |
Glp-1 formulations with protracted time action
|
|
CA2458371A1
(en)
|
2001-08-23 |
2003-03-06 |
Eli Lilly And Company |
Glucagon-like peptide-1 analogs
|
|
ES2425738T3
(es)
|
2001-12-21 |
2013-10-17 |
Human Genome Sciences, Inc. |
Proteínas de fusión de la albúmina
|
|
CN1332711C
(zh)
|
2002-02-20 |
2007-08-22 |
埃米球科技有限公司 |
施用glp-1分子的方法
|
|
US20030191056A1
(en)
*
|
2002-04-04 |
2003-10-09 |
Kenneth Walker |
Use of transthyretin peptide/protein fusions to increase the serum half-life of pharmacologically active peptides/proteins
|
|
US9321832B2
(en)
|
2002-06-28 |
2016-04-26 |
Domantis Limited |
Ligand
|
|
PL377591A1
(pl)
*
|
2002-10-02 |
2006-02-06 |
Zealand Pharma A/S |
Stabilizowane związki eksendyny-4
|
|
US7731947B2
(en)
|
2003-11-17 |
2010-06-08 |
Intarcia Therapeutics, Inc. |
Composition and dosage form comprising an interferon particle formulation and suspending vehicle
|
|
NZ554885A
(en)
*
|
2002-12-31 |
2009-07-31 |
Altus Pharmaceuticals Inc |
Complexes of hgh crystals and protamine polymers
|
|
EP1594530A4
(de)
|
2003-01-22 |
2006-10-11 |
Human Genome Sciences Inc |
Albuminfusionsproteine
|
|
JP4548335B2
(ja)
*
|
2003-03-07 |
2010-09-22 |
味の素株式会社 |
腸管細胞のインスリン産生細胞への変換誘導剤、及び糖尿病治療剤
|
|
EA009366B1
(ru)
*
|
2003-03-19 |
2007-12-28 |
Эли Лилли Энд Компани |
Связанные с полиэтиленгликолем соединения гпп-1
|
|
PT1656370E
(pt)
|
2003-06-03 |
2012-11-29 |
Rib X Pharmaceuticals Inc |
Compostos biaril-heterocíclicos e métodos de os produzir e de os utilizar
|
|
RU2246964C1
(ru)
*
|
2003-10-23 |
2005-02-27 |
Государственное образовательное учреждение высшего профессионального образования "Сибирский государственный медицинский университет" Министерства здравоохранения Российской Федерации (ГОУВПО СибГМУ) |
Средство, обладающее гиполипидемическим, антиоксидантным и гипогликемическим действием, для лечения сердечно- сосудистых и эндокринных заболеваний и способ его применения
|
|
EP1694356B1
(de)
|
2003-12-09 |
2011-02-16 |
Novo Nordisk A/S |
Regulierung der nahrungspräferenz mit glp-1-agonisten
|
|
WO2005058252A2
(en)
|
2003-12-16 |
2005-06-30 |
Societe De Conseils De Recherches Et D'applications Scientifiques S.A.S. |
Glp-1 pharmaceutical compositions
|
|
US20060286129A1
(en)
|
2003-12-19 |
2006-12-21 |
Emisphere Technologies, Inc. |
Oral GLP-1 formulations
|
|
JP2008501765A
(ja)
|
2004-06-11 |
2008-01-24 |
ノボ ノルディスク アクティーゼルスカブ |
Glp−1アゴニストを用いた薬剤誘発性肥満の中和
|
|
JP5185624B2
(ja)
|
2004-12-02 |
2013-04-17 |
ドマンティス リミテッド |
血清アルブミンおよびglp−1またはpyyを標的とする二重特異性抗体
|
|
US11246913B2
(en)
|
2005-02-03 |
2022-02-15 |
Intarcia Therapeutics, Inc. |
Suspension formulation comprising an insulinotropic peptide
|
|
WO2006083761A2
(en)
|
2005-02-03 |
2006-08-10 |
Alza Corporation |
Solvent/polymer solutions as suspension vehicles
|
|
TW200643033A
(en)
*
|
2005-03-08 |
2006-12-16 |
Chugai Pharmaceutical Co Ltd |
Conjugate of water-soluble modified hyaluronic acid and glp-1 analogue
|
|
GB0511269D0
(en)
|
2005-06-02 |
2005-07-13 |
Creative Peptides Sweden Ab |
Sustained release preparation of pro-insulin C-peptide
|
|
NZ565535A
(en)
|
2005-06-30 |
2011-03-31 |
Ipsen Pharma Sas |
GLP-1 pharmaceutical compositions
|
|
JP5096363B2
(ja)
|
2005-12-16 |
2012-12-12 |
ネクター セラピューティックス |
Glp−1のポリマ複合体
|
|
MX2008013168A
(es)
*
|
2006-04-13 |
2008-10-27 |
Sod Conseils Rech Applic |
Composiciones faramaceuticas del peptido 1 similar al glucagon humano, exendina-4 y análogos de los mismos.
|
|
MX2008013304A
(es)
|
2006-04-20 |
2008-10-27 |
Amgen Inc |
Compuestos de peptido 1 tipo glucagon.
|
|
WO2007140416A2
(en)
|
2006-05-30 |
2007-12-06 |
Intarcia Therapeutics, Inc. |
Two-piece, internal-channel osmotic delivery system flow modulator
|
|
PT2359808E
(pt)
|
2006-08-09 |
2013-08-28 |
Intarcia Therapeutics Inc |
Sistemas de entrega osmótica e montagens de pistão
|
|
ES2402172T3
(es)
|
2007-04-23 |
2013-04-29 |
Intarcia Therapeutics, Inc |
Formulación en suspensión de péptidos insulinotrópicos y usos de los mismos
|
|
WO2009102467A2
(en)
|
2008-02-13 |
2009-08-20 |
Intarcia Therapeutics, Inc. |
Devices, formulations, and methods for delivery of multiple beneficial agents
|
|
KR20130133104A
(ko)
*
|
2008-08-07 |
2013-12-05 |
입센 파마 에스.에이.에스 |
포도당 의존적인 인슐린 분비 자극성 폴리펩타이드 유사체
|
|
CA2733005C
(en)
*
|
2008-08-07 |
2016-09-27 |
Ipsen Pharma S.A.S. |
Truncated analogues of glucose-dependent insulinotropic polypeptide
|
|
EP2328922A4
(de)
*
|
2008-08-07 |
2013-01-02 |
Ipsen Pharma Sas |
Analoga des glucoseabhängigen insulinotropen polypeptids
|
|
CN102281865B
(zh)
*
|
2008-10-15 |
2017-04-05 |
精达制药公司 |
高浓缩药物颗粒、制剂、混悬剂及其应用
|
|
EP2216042A1
(de)
|
2009-02-09 |
2010-08-11 |
Ipsen Pharma S.A.S. |
GLP1-analoge pharmazeutische Zusammensetzungen
|
|
EP3735944A1
(de)
|
2009-09-28 |
2020-11-11 |
Intarcia Therapeutics, Inc. |
Schnelle initiierung und/oder beendigung der verabreichung substantiell stabiler arzneimittel
|
|
WO2012054822A1
(en)
|
2010-10-22 |
2012-04-26 |
Nektar Therapeutics |
Pharmacologically active polymer-glp-1 conjugates
|
|
WO2012054861A1
(en)
|
2010-10-22 |
2012-04-26 |
Nektar Therapeutics |
Glp-1 polymer conjugates having a releasable linkage
|
|
US20120157382A1
(en)
|
2010-12-21 |
2012-06-21 |
Siegfried Krimmer |
Pharmaceutical glp-1 compositions having an improved release profile
|
|
US20140045754A1
(en)
*
|
2011-01-19 |
2014-02-13 |
Joern Drustrup |
Glp-1 compositions
|
|
US20120208755A1
(en)
|
2011-02-16 |
2012-08-16 |
Intarcia Therapeutics, Inc. |
Compositions, Devices and Methods of Use Thereof for the Treatment of Cancers
|
|
CN102643339B
(zh)
*
|
2011-02-21 |
2014-04-09 |
天津药物研究院 |
一种glp-1类似物、制备方法及其应用
|
|
UA116217C2
(uk)
|
2012-10-09 |
2018-02-26 |
Санофі |
Пептидна сполука як подвійний агоніст рецепторів glp1-1 та глюкагону
|
|
SG10201705097PA
(en)
|
2012-12-21 |
2017-07-28 |
Sanofi Sa |
Functionalized exendin-4 derivatives
|
|
US9528648B2
(en)
|
2013-03-15 |
2016-12-27 |
Opw Fueling Components Inc. |
Breakaway assembly with relief valve
|
|
EP3080149A1
(de)
|
2013-12-13 |
2016-10-19 |
Sanofi |
Duale glp-1-/glucagon-rezeptoragonisten
|
|
WO2015086729A1
(en)
|
2013-12-13 |
2015-06-18 |
Sanofi |
Dual glp-1/gip receptor agonists
|
|
TW201609795A
(zh)
|
2013-12-13 |
2016-03-16 |
賽諾菲公司 |
作為雙重glp-1/gip受體促效劑的艾塞那肽-4(exendin-4)胜肽類似物
|
|
WO2015086730A1
(en)
|
2013-12-13 |
2015-06-18 |
Sanofi |
Non-acylated exendin-4 peptide analogues
|
|
TW201625670A
(zh)
|
2014-04-07 |
2016-07-16 |
賽諾菲公司 |
衍生自exendin-4之雙重glp-1/升糖素受體促效劑
|
|
TW201625668A
(zh)
|
2014-04-07 |
2016-07-16 |
賽諾菲公司 |
作為胜肽性雙重glp-1/昇糖素受體激動劑之艾塞那肽-4衍生物
|
|
TW201625669A
(zh)
|
2014-04-07 |
2016-07-16 |
賽諾菲公司 |
衍生自艾塞那肽-4(Exendin-4)之肽類雙重GLP-1/升糖素受體促效劑
|
|
US9932381B2
(en)
|
2014-06-18 |
2018-04-03 |
Sanofi |
Exendin-4 derivatives as selective glucagon receptor agonists
|
|
US9889085B1
(en)
|
2014-09-30 |
2018-02-13 |
Intarcia Therapeutics, Inc. |
Therapeutic methods for the treatment of diabetes and related conditions for patients with high baseline HbA1c
|
|
AR105616A1
(es)
|
2015-05-07 |
2017-10-25 |
Lilly Co Eli |
Proteínas de fusión
|
|
KR102650751B1
(ko)
|
2015-06-03 |
2024-03-22 |
인타르시아 세라퓨틱스 인코포레이티드 |
임플란트 배치 및 제거 시스템들
|
|
AR105319A1
(es)
|
2015-06-05 |
2017-09-27 |
Sanofi Sa |
Profármacos que comprenden un conjugado agonista dual de glp-1 / glucagón conector ácido hialurónico
|
|
AR105284A1
(es)
|
2015-07-10 |
2017-09-20 |
Sanofi Sa |
Derivados de exendina-4 como agonistas peptídicos duales específicos de los receptores de glp-1 / glucagón
|
|
CN109310743A
(zh)
|
2016-05-16 |
2019-02-05 |
因塔西亚制药公司 |
胰高血糖素受体选择性多肽及其使用方法
|
|
USD840030S1
(en)
|
2016-06-02 |
2019-02-05 |
Intarcia Therapeutics, Inc. |
Implant placement guide
|
|
USD860451S1
(en)
|
2016-06-02 |
2019-09-17 |
Intarcia Therapeutics, Inc. |
Implant removal tool
|
|
AU2018206539A1
(en)
|
2017-01-03 |
2019-07-18 |
Intarcia Therapeutics, Inc. |
Methods comprising continuous administration of a GLP-1 receptor agonist and co-administration of a drug
|
|
TWI705820B
(zh)
|
2018-06-22 |
2020-10-01 |
美商美國禮來大藥廠 |
Gip/glp1促效劑組合物
|
|
EP3628683A1
(de)
*
|
2018-09-28 |
2020-04-01 |
Zealand Pharma A/S |
Formulierungen von analoga des glucagon-like-peptid-2 (glp-2)
|
|
CN113912673B
(zh)
*
|
2021-11-09 |
2024-02-09 |
河南省农业科学院 |
一种芝麻来源的低苦味ace抑制肽及其制备方法和应用
|
|
AR129357A1
(es)
|
2022-05-18 |
2024-08-14 |
Protomer Tech Inc |
Compuestos aromáticos que contienen boro y análogos de insulina relacionados
|