ATE315025T1 - Ethansulfonyl-piperidin-derivate - Google Patents

Ethansulfonyl-piperidin-derivate

Info

Publication number: ATE315025T1
Authority: AT; Austria
Prior art keywords: ethanesulfonyl; piperidine derivatives; piperidine; derivatives; ethanesulfonyl piperidine
Prior art date: 1999-06-08

Application number

AT00936835T

Other languages

English (en)

Inventor

Alexander Alanine

Serge Burner

Bernd Buettelmann

Neidhart Marie-Paule Heitz

Georg Jaeschke

Emmanuel Pinard

Rene Wyler

Original Assignee

Hoffmann La Roche

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1999-06-08

Filing date

2000-05-31

Publication date

2006-02-15

2000-05-31 Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche

2006-02-15 Application granted granted Critical

2006-02-15 Publication of ATE315025T1 publication Critical patent/ATE315025T1/de

Links

GZJHPGLSIOWQJE-UHFFFAOYSA-N 1-ethylsulfonylpiperidine Chemical class CCS(=O)(=O)N1CCCCC1 GZJHPGLSIOWQJE-UHFFFAOYSA-N 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D211/40—Oxygen atoms
- C07D211/44—Oxygen atoms attached in position 4
- C07D211/46—Oxygen atoms attached in position 4 having a hydrogen atom as the second substituent in position 4
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D211/54—Sulfur atoms
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
- C07D211/10—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with radicals containing only carbon and hydrogen atoms attached to ring carbon atoms
- C07D211/14—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with radicals containing only carbon and hydrogen atoms attached to ring carbon atoms with hydrocarbon or substituted hydrocarbon radicals attached to the ring nitrogen atom
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D211/40—Oxygen atoms
- C07D211/42—Oxygen atoms attached in position 3 or 5

Landscapes

Health & Medical Sciences (AREA)
Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Neurology (AREA)
Biomedical Technology (AREA)
Neurosurgery (AREA)
Life Sciences & Earth Sciences (AREA)
Public Health (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Pharmacology & Pharmacy (AREA)
Veterinary Medicine (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
General Chemical & Material Sciences (AREA)
Psychiatry (AREA)
Psychology (AREA)
Pain & Pain Management (AREA)
Hospice & Palliative Care (AREA)
Orthopedic Medicine & Surgery (AREA)
Physical Education & Sports Medicine (AREA)
Hydrogenated Pyridines (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

AT00936835T 1999-06-08 2000-05-31 Ethansulfonyl-piperidin-derivate ATE315025T1 (de)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
EP99111126		1999-06-08

Publications (1)

Publication Number	Publication Date
ATE315025T1 true ATE315025T1 (de)	2006-02-15

Family

ID=8238316

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT00936835T ATE315025T1 (de)	1999-06-08	2000-05-31	Ethansulfonyl-piperidin-derivate

Country Status (38)

Country	Link
US (1)	US6310213B1 (de)
EP (1)	EP1189886B1 (de)
JP (1)	JP3645856B2 (de)
KR (1)	KR100571162B1 (de)
CN (1)	CN1142141C (de)
AR (1)	AR024282A1 (de)
AT (1)	ATE315025T1 (de)
AU (1)	AU770787B2 (de)
BR (1)	BR0011419A (de)
CA (1)	CA2376091C (de)
CO (1)	CO5160328A1 (de)
CZ (1)	CZ299483B6 (de)
DE (1)	DE60025348T2 (de)
DK (1)	DK1189886T3 (de)
EG (1)	EG26101A (de)
ES (1)	ES2254183T3 (de)
GC (1)	GC0000256A (de)
GT (1)	GT200000089A (de)
HK (1)	HK1046412B (de)
HR (1)	HRP20010885B1 (de)
HU (1)	HU228591B1 (de)
IL (2)	IL146750A0 (de)
JO (1)	JO2260B1 (de)
MA (1)	MA26797A1 (de)
MX (1)	MXPA01012585A (de)
MY (1)	MY128818A (de)
NO (1)	NO320613B1 (de)
PA (1)	PA8496601A1 (de)
PE (1)	PE20010218A1 (de)
PL (1)	PL196053B1 (de)
RS (1)	RS50033B (de)
RU (1)	RU2242464C2 (de)
SI (1)	SI1189886T1 (de)
TN (1)	TNSN00125A1 (de)
TR (1)	TR200103532T2 (de)
TW (1)	TWI254043B (de)
WO (1)	WO2000075109A1 (de)
ZA (1)	ZA200109706B (de)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
ES2225330T3 (es)	2000-03-22	2005-03-16	Hoffmann La Roche	Compuesto de piperidina y piperacina para empleo en el tratamiento de alzheimer.
JP4219590B2 (ja)	2000-04-20	2009-02-04	エフ．ホフマン−ラロシュアーゲー	ピロリジン及びピペリジン誘導体並びに神経変性障害の治療のためのこれらの使用
PA8525601A1 (es)	2000-08-21	2002-04-25	Hoffmann La Roche	Profarmacos de (3s,4s)-4-bencil-1-[2-(4-hidroxi-bencenosulfonil)-etil]-piperidin-3-ol
WO2002031499A1 (en) *	2000-10-09	2002-04-18	Unisearch Limited	Detection of neurodegenerative disorders
US6951875B2 (en)	2001-10-29	2005-10-04	Hoffmann-La Roche Inc.	Conjugated aromatic compounds with a pyridine substituent
US7005432B2 (en) *	2002-05-16	2006-02-28	Hoffman-La Roche Inc.	Substituted imidazol-pyridazine derivatives
RU2268715C1 (ru) *	2004-06-22	2006-01-27	ГУ "Научно-исследовательский институт экспериментальной медицины" РАМН (ГУ НИИЭМ РАМН)	Нейропротекторное средство
US20110053951A1 (en) *	2008-03-27	2011-03-03	Evotec Neurosciences Gmbh	Methods for treating disorders using nmda nr2b-subtype selective antagonist
IN2014DN00137A (de) *	2011-07-18	2015-05-22	Adolor Corp
TWI922934B (zh) *	2023-04-20	2026-04-21	大陸商紐歐申醫藥（上海）有限公司	含氮雜環類化合物及其製備方法和應用

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
AU655840B2 (en) *	1991-07-17	1995-01-12	Pfizer Inc.	2-(4-hydroxypiperidino)-1-alkanol derivatives as antiischemic agents
DE4410822A1 (de) *	1994-03-24	1995-09-28	Schering Ag	Neue Piperidin-Derivate
ZA9610745B (en) *	1995-12-22	1997-06-24	Warner Lambert Co	4-Subsituted piperidine analogs and their use as subtype selective nmda receptor antagonists
TW498067B (en) *	1996-07-19	2002-08-11	Hoffmann La Roche	4-hydroxy-piperidine derivatives

2000
- 2000-05-24 TW TW089109992A patent/TWI254043B/zh not_active IP Right Cessation
- 2000-05-31 AT AT00936835T patent/ATE315025T1/de active
- 2000-05-31 EP EP00936835A patent/EP1189886B1/de not_active Expired - Lifetime
- 2000-05-31 BR BR0011419-7A patent/BR0011419A/pt not_active Application Discontinuation
- 2000-05-31 PL PL00352723A patent/PL196053B1/pl unknown
- 2000-05-31 HU HU0201916A patent/HU228591B1/hu not_active IP Right Cessation
- 2000-05-31 JP JP2001501590A patent/JP3645856B2/ja not_active Expired - Fee Related
- 2000-05-31 RS YUP-865/01A patent/RS50033B/sr unknown
- 2000-05-31 CZ CZ20014349A patent/CZ299483B6/cs not_active IP Right Cessation
- 2000-05-31 TR TR2001/03532T patent/TR200103532T2/xx unknown
- 2000-05-31 AU AU52181/00A patent/AU770787B2/en not_active Ceased
- 2000-05-31 SI SI200030793T patent/SI1189886T1/sl unknown
- 2000-05-31 CN CNB008086028A patent/CN1142141C/zh not_active Expired - Fee Related
- 2000-05-31 CA CA002376091A patent/CA2376091C/en not_active Expired - Fee Related
- 2000-05-31 DE DE60025348T patent/DE60025348T2/de not_active Expired - Lifetime
- 2000-05-31 HR HR20010885A patent/HRP20010885B1/xx not_active IP Right Cessation
- 2000-05-31 WO PCT/EP2000/004953 patent/WO2000075109A1/en not_active Ceased
- 2000-05-31 HK HK02108022.3A patent/HK1046412B/zh not_active IP Right Cessation
- 2000-05-31 IL IL14675000A patent/IL146750A0/xx active IP Right Grant
- 2000-05-31 KR KR1020017015765A patent/KR100571162B1/ko not_active Expired - Fee Related
- 2000-05-31 RU RU2001135806/04A patent/RU2242464C2/ru not_active IP Right Cessation
- 2000-05-31 ES ES00936835T patent/ES2254183T3/es not_active Expired - Lifetime
- 2000-05-31 DK DK00936835T patent/DK1189886T3/da active
- 2000-05-31 MX MXPA01012585A patent/MXPA01012585A/es active IP Right Grant
- 2000-06-02 PE PE2000000547A patent/PE20010218A1/es not_active Application Discontinuation
- 2000-06-02 US US09/585,755 patent/US6310213B1/en not_active Expired - Lifetime
- 2000-06-03 TN TNTNSN00125A patent/TNSN00125A1/fr unknown
- 2000-06-05 PA PA20008496601A patent/PA8496601A1/es unknown
- 2000-06-05 EG EG2000060739A patent/EG26101A/en active
- 2000-06-05 AR ARP000102775A patent/AR024282A1/es active IP Right Grant
- 2000-06-06 MY MYPI20002522A patent/MY128818A/en unknown
- 2000-06-07 JO JO200087A patent/JO2260B1/en active
- 2000-06-07 CO CO00042340A patent/CO5160328A1/es unknown
- 2000-06-07 GC GCP2000702 patent/GC0000256A/en active
- 2000-06-07 GT GT200000089A patent/GT200000089A/es unknown
2001
- 2001-11-26 ZA ZA200109706A patent/ZA200109706B/en unknown
- 2001-11-26 IL IL146750A patent/IL146750A/en not_active IP Right Cessation
- 2001-12-04 NO NO20015920A patent/NO320613B1/no not_active IP Right Cessation
- 2001-12-07 MA MA26438A patent/MA26797A1/fr unknown

Also Published As

Publication number	Publication date
CA2376091C (en)	2006-03-14
US6310213B1 (en)	2001-10-30
RU2242464C2 (ru)	2004-12-20
IL146750A0 (en)	2002-07-25
AR024282A1 (es)	2002-09-25
MXPA01012585A (es)	2002-04-10
DK1189886T3 (da)	2006-05-15
NO320613B1 (no)	2005-12-27
KR100571162B1 (ko)	2006-04-17
WO2000075109A1 (en)	2000-12-14
AU5218100A (en)	2000-12-28
GT200000089A (es)	2001-11-29
CN1142141C (zh)	2004-03-17
HU228591B1 (hu)	2013-04-29
PE20010218A1 (es)	2001-02-28
EP1189886A1 (de)	2002-03-27
HK1046412B (zh)	2004-07-09
HRP20010885B1 (en)	2010-07-31
ES2254183T3 (es)	2006-06-16
ZA200109706B (en)	2003-02-26
KR20020008850A (ko)	2002-01-31
AU770787B2 (en)	2004-03-04
PL196053B1 (pl)	2007-11-30
NO20015920D0 (no)	2001-12-04
EG26101A (en)	2013-02-17
DE60025348D1 (de)	2006-03-30
TR200103532T2 (tr)	2002-05-21
MY128818A (en)	2007-02-28
DE60025348T2 (de)	2006-08-24
BR0011419A (pt)	2002-02-26
IL146750A (en)	2006-12-10
CN1354745A (zh)	2002-06-19
RS50033B (sr)	2008-11-28
TNSN00125A1 (fr)	2005-11-10
CA2376091A1 (en)	2000-12-14
HK1046412A1 (en)	2003-01-10
EP1189886B1 (de)	2006-01-04
CO5160328A1 (es)	2002-05-30
SI1189886T1 (sl)	2006-04-30
MA26797A1 (fr)	2004-12-20
HUP0201916A2 (en)	2002-10-28
HUP0201916A3 (en)	2003-05-28
TWI254043B (en)	2006-05-01
HRP20010885A2 (en)	2004-02-29
YU86501A (sh)	2004-09-03
JP3645856B2 (ja)	2005-05-11
GC0000256A (en)	2006-11-01
JO2260B1 (en)	2004-10-07
PA8496601A1 (es)	2001-12-14
JP2003501415A (ja)	2003-01-14
NO20015920L (no)	2001-12-04
CZ20014349A3 (cs)	2002-05-15
PL352723A1 (en)	2003-09-08
CZ299483B6 (cs)	2008-08-13

Legal Events

Date

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2006-09-15

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DK1187815T3 (da)	2006-06-19	4-phenyl-pyrimidinderivater
DE60021384D1 (de)	2005-08-25	Indolderivate
NO20015920L (no)	2001-12-04	Etansulfonyl-piperidin-derivater
IS6434A (is)	2002-06-19	Nýjar indól afleiður
NO20020306D0 (no)	2002-01-21	Indolderivater
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TR199800596A3 (tr)	1998-10-21	Fenoksimetil piperidin türevleri