ATE315091T1 - Modifizierte zellen auf der basis des betain- katabolismus, herstellung und verwendung insbesondere zur herstellung von metaboliten oder enzymen - Google Patents

Modifizierte zellen auf der basis des betain- katabolismus, herstellung und verwendung insbesondere zur herstellung von metaboliten oder enzymen

Info

Publication number
ATE315091T1
ATE315091T1 AT94901994T AT94901994T ATE315091T1 AT E315091 T1 ATE315091 T1 AT E315091T1 AT 94901994 T AT94901994 T AT 94901994T AT 94901994 T AT94901994 T AT 94901994T AT E315091 T1 ATE315091 T1 AT E315091T1
Authority
AT
Austria
Prior art keywords
production
enzymes
catabolism
metabolites
betain
Prior art date
Application number
AT94901994T
Other languages
English (en)
Inventor
Beatrice Cameron
Joel Crouzet
Original Assignee
Rhone Poulenc Biochimie
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=9436376&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ATE315091(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Rhone Poulenc Biochimie filed Critical Rhone Poulenc Biochimie
Application granted granted Critical
Publication of ATE315091T1 publication Critical patent/ATE315091T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C12P19/26—Preparation of nitrogen-containing carbohydrates
    • C12P19/28—N-glycosides
    • C12P19/42—Cobalamins, i.e. vitamin B12, LLD factor
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/52—Genes encoding for enzymes or proenzymes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/67—General methods for enhancing the expression
    • C12N15/68—Stabilisation of the vector
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/74—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora

Landscapes

  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
AT94901994T 1992-12-09 1993-12-07 Modifizierte zellen auf der basis des betain- katabolismus, herstellung und verwendung insbesondere zur herstellung von metaboliten oder enzymen ATE315091T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9214814A FR2698879B1 (fr) 1992-12-09 1992-12-09 gellules modifiées au niveau du catabolisme de la bétaïne, préparation et utilisations, notamment pour la production de métabolites ou d'enzymes.

Publications (1)

Publication Number Publication Date
ATE315091T1 true ATE315091T1 (de) 2006-02-15

Family

ID=9436376

Family Applications (1)

Application Number Title Priority Date Filing Date
AT94901994T ATE315091T1 (de) 1992-12-09 1993-12-07 Modifizierte zellen auf der basis des betain- katabolismus, herstellung und verwendung insbesondere zur herstellung von metaboliten oder enzymen

Country Status (10)

Country Link
US (2) US5691163A (de)
EP (1) EP0673422B1 (de)
JP (1) JP3488924B2 (de)
AT (1) ATE315091T1 (de)
CA (1) CA2151123C (de)
DE (1) DE69333962T2 (de)
DK (1) DK0673422T3 (de)
ES (1) ES2255052T3 (de)
FR (1) FR2698879B1 (de)
WO (1) WO1994013813A1 (de)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0966521A1 (de) * 1996-09-13 1999-12-29 Novo Nordisk Biotech, Inc. Zellen mit dna-insertionsmutationenwelche veränderte mengen eines polypeptids produzieren
EP1112352A2 (de) * 1998-08-20 2001-07-04 Danisco Finland OY Methyltransferasen, dafür kodierende nukleinsäuremoleküle, deren rekombinante expression und verwendungen
DE60307294D1 (de) * 2002-09-27 2006-09-14 Dsm Ip Assets Bv Transkriptionsaktivator-gen für gene, die beteiligt sind an der biosynthese von cobalamin
US9328326B2 (en) * 2006-08-10 2016-05-03 Merck Patent Gmbh Method for isolating cells
EP2552465B1 (de) 2010-03-31 2015-04-22 Stabilitech Ltd. Stabilisierung von viruspartikeln
JP5869553B2 (ja) * 2010-03-31 2016-02-24 スタビリテック リミテッド ウイルス粒子、ポリペプチド又は生体材料を安定化させる添加剤
GB201117233D0 (en) 2011-10-05 2011-11-16 Stabilitech Ltd Stabilisation of polypeptides
CN104345851A (zh) * 2013-07-24 2015-02-11 鸿富锦精密电子(天津)有限公司 电源电路
GB201406569D0 (en) 2014-04-11 2014-05-28 Stabilitech Ltd Vaccine compositions
GB2562241B (en) 2017-05-08 2022-04-06 Stabilitech Biopharma Ltd Vaccine compositions

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS55148084A (en) * 1979-05-08 1980-11-18 Mitsubishi Gas Chem Co Inc Incubation of microoranism
JPS62181791A (ja) * 1986-02-04 1987-08-10 Ajinomoto Co Inc 発酵法によるｌ−アミノ酸又は５′−イノシン酸の製造法
FR2657622B1 (fr) 1990-01-31 1994-11-25 Rhone Poulenc Sante Polypeptides impliques dans la biosynthese des cobalamines et/ou des cobamides, sequences d'adn codant pour ces polypeptides, procede de preparation, et leur utilisation.
RU2099418C1 (ru) * 1991-11-21 1997-12-20 Лонца Аг Фрагмент днк, обеспечивающий использование бетаина, рекомбинантная плазмидная днк с фрагментом днк, обеспечивающим использование бетаина, штамм бактерий rhizobium/agrobacterium, предназначенный для стабильного хранения плазмиды с фрагментом днк, способ получения штамма бактерий

Also Published As

Publication number Publication date
FR2698879B1 (fr) 1995-01-13
DK0673422T3 (da) 2006-05-15
EP0673422A1 (de) 1995-09-27
US5691163A (en) 1997-11-25
JPH08505286A (ja) 1996-06-11
DE69333962T2 (de) 2006-08-24
DE69333962D1 (de) 2006-03-30
EP0673422B1 (de) 2006-01-04
WO1994013813A1 (fr) 1994-06-23
USRE38331E1 (en) 2003-11-25
JP3488924B2 (ja) 2004-01-19
ES2255052T3 (es) 2006-06-16
CA2151123C (fr) 2007-01-30
FR2698879A1 (fr) 1994-06-10
CA2151123A1 (fr) 1994-06-23

Similar Documents

Publication Publication Date Title
DE59410052D1 (de) Verwendung von nona- und dekapeptiden zur herstellung eines arzneimittels zur bekämpfung von aids
EE9900105A (et) Bensonaftüridiinid bronhiaalravimitena
ATE347585T1 (de) In-vitro wachstum von langerhans'schen inseln und ihre verwendungen
IT1276071B1 (it) Compositi ad attivita' anti-infiammatoria
DE69428791D1 (de) Verwendung vonModafinil zur Behandlung von Atemstillstand im Schlaf und zentral erregten Atembeschwerden
ATE407138T1 (de) Verfahren zur herstellung interferierender rna- moleküle in säugetierzellen und therapeutische anwendungen solcher moleküle
UA81398C2 (en) Keratinocytes which may be used as biologically active substances for the treatment of wounds
DE69534618D1 (de) Verfahren zur herstellung rekombinanter adeno-associated viren (aav) und deren verwendung
DE69513167D1 (de) Perfluoroalkyll ketone, inhibitoren von elastase und prozess zur deren herstellung
DE59608203D1 (de) PYRAZOLO- 1,5a]-PYRIMIDINE, VERFAHREN ZU IHRER HERSTELLUNG UND IHRE VERWENDUNG
DE69622413D1 (de) Zusammensetzbares spielgerät,insbesondere zur herstellung von rollbahnen
ATE315091T1 (de) Modifizierte zellen auf der basis des betain- katabolismus, herstellung und verwendung insbesondere zur herstellung von metaboliten oder enzymen
BR9607335A (pt) Compostos 1-aril-2-acrilamino-etano e seu uso como neuroquinina especialmente antogonistas de neuroquinina 1
ATE272404T1 (de) Verwendung von taurolidine zur herstellung eines arzneimittels zur behandlung von leukämien
FI942442A0 (fi) Proteiinien tuotto 7B2-proteiinia käyttäen
ATE440144T1 (de) Die verwendung von abc transporter kodierenden genen zur stimulierung der herstellung von sekundärmetaboliten in biologischen zellen
DE69803383D1 (de) Selektive inhibitoren des faktors x, eine azepinonstruktur enthaltend
DE69626816D1 (de) Verwendung von selegilin zur behandlung von gehörverlust bei säugetieren
MX9604762A (es) Nuevas sulfonamidas y procedimiento para su preparacion.
AU3862997A (en) Stable derivatives of ubiquinole, processes for their production and pharmaceutical use thereof
ATE264112T1 (de) Verwendung von il-7 zur behandlung von autoimmunkrankheiten, insbesondere insulinabhängigem diabetes mellitus
AU6700996A (en) Somatostatin-analogous cyclic peptides with inhibitory activity on growth hormone
DE59402079D1 (de) Benzo[f]chinoxalindionderivative, deren herstellung und verwendung in arzneimitteln
DE69425061D1 (de) Verwendung von einer suspension auf der basis von sucralfatgel als antazidum
ATE215368T1 (de) Verwendung von forskolin oder diese enthaltende extrakte zur herstellung eines medikaments für die behandlung von alkoholsucht

Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification

Ref document number: 0673422

Country of ref document: EP