ATE317700T1 - Verwendung von (11beta, 17beta)-11-(1,3- benzodioxol-5-yl)-17-hydroxy-17-(1-propinyl)- estra-4,9-dien-3-on zur behandlung von schweren depressionen - Google Patents

Verwendung von (11beta, 17beta)-11-(1,3- benzodioxol-5-yl)-17-hydroxy-17-(1-propinyl)- estra-4,9-dien-3-on zur behandlung von schweren depressionen

Info

Publication number: ATE317700T1
Authority: AT; Austria
Prior art keywords: estra; benzodioxol; dien; hydroxy; treatment
Prior art date: 2001-10-26

Application number

AT02781273T

Other languages

English (en)

Inventor

Cornelis Sennef

Bernardus Wijnand M M Peeters

Original Assignee

Akzo Nobel Nv

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2001-10-26

Filing date

2002-10-21

Publication date

2006-03-15

2002-10-21 Application filed by Akzo Nobel Nv filed Critical Akzo Nobel Nv

2006-03-15 Application granted granted Critical

2006-03-15 Publication of ATE317700T1 publication Critical patent/ATE317700T1/de

Links

DFELGYQKEOCHOA-BZAFBGKRSA-N (8s,11r,13s,14s,17s)-11-(1,3-benzodioxol-5-yl)-17-hydroxy-13-methyl-17-prop-1-ynyl-1,2,6,7,8,11,12,14,15,16-decahydrocyclopenta[a]phenanthren-3-one Chemical compound C1=C2OCOC2=CC([C@@H]2C3=C4CCC(=O)C=C4CC[C@H]3[C@@H]3CC[C@@]([C@]3(C2)C)(O)C#CC)=C1 DFELGYQKEOCHOA-BZAFBGKRSA-N 0.000 abstract 2
DBLOJPKZEOYNBN-SQNIBIBYSA-N (8s,13s,14s)-13-methyl-2,6,7,8,11,12,14,15,16,17-decahydro-1h-cyclopenta[a]phenanthren-3-one Chemical compound C1CC2=CC(=O)CCC2=C2[C@@H]1[C@@H]1CCC[C@@]1(C)CC2 DBLOJPKZEOYNBN-SQNIBIBYSA-N 0.000 abstract 1
208000020401 Depressive disease Diseases 0.000 abstract 1
239000003814 drug Substances 0.000 abstract 1
229940126013 glucocorticoid receptor antagonist Drugs 0.000 abstract 1
239000003850 glucocorticoid receptor antagonist Substances 0.000 abstract 1
239000000825 pharmaceutical preparation Substances 0.000 abstract 1
238000002360 preparation method Methods 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/58—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Epidemiology (AREA)
Engineering & Computer Science (AREA)
Chemical Kinetics & Catalysis (AREA)
Pain & Pain Management (AREA)
Bioinformatics & Cheminformatics (AREA)
Biomedical Technology (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Psychiatry (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Organic Chemistry (AREA)
Steroid Compounds (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

AT02781273T 2001-10-26 2002-10-21 Verwendung von (11beta, 17beta)-11-(1,3- benzodioxol-5-yl)-17-hydroxy-17-(1-propinyl)- estra-4,9-dien-3-on zur behandlung von schweren depressionen ATE317700T1 (de)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
EP01204072		2001-10-26

Publications (1)

Publication Number	Publication Date
ATE317700T1 true ATE317700T1 (de)	2006-03-15

Family

ID=8181136

Family Applications (2)

Application Number	Title	Priority Date	Filing Date
AT06101005T ATE420649T1 (de)	2001-10-26	2002-10-21	Verwendung von (11beta, 17beta)-11-(1,3- benzodioxol-5-yl)-17-hydroxy-17-(1-propinyl)- estra-4,9-dien-3-on zur behandlung von schweren depressionen
AT02781273T ATE317700T1 (de)	2001-10-26	2002-10-21	Verwendung von (11beta, 17beta)-11-(1,3- benzodioxol-5-yl)-17-hydroxy-17-(1-propinyl)- estra-4,9-dien-3-on zur behandlung von schweren depressionen

Family Applications Before (1)

Application Number	Title	Priority Date	Filing Date
AT06101005T ATE420649T1 (de)	2001-10-26	2002-10-21	Verwendung von (11beta, 17beta)-11-(1,3- benzodioxol-5-yl)-17-hydroxy-17-(1-propinyl)- estra-4,9-dien-3-on zur behandlung von schweren depressionen

Country Status (26)

Country	Link
US (1)	US20040266863A1 (de)
EP (2)	EP1441739B1 (de)
JP (1)	JP4647909B2 (de)
KR (1)	KR20050038580A (de)
CN (1)	CN100531738C (de)
AT (2)	ATE420649T1 (de)
AU (1)	AU2002348996B2 (de)
BR (1)	BR0213466A (de)
CA (1)	CA2463446C (de)
CY (1)	CY1110173T1 (de)
DE (2)	DE60230936D1 (de)
DK (1)	DK1652526T3 (de)
EC (1)	ECSP045080A (de)
ES (1)	ES2319563T3 (de)
HR (1)	HRP20040370B1 (de)
HU (1)	HUP0500070A3 (de)
IL (2)	IL161248A0 (de)
IS (1)	IS2702B (de)
MX (1)	MXPA04003781A (de)
NO (1)	NO332978B1 (de)
NZ (1)	NZ532429A (de)
PL (1)	PL206687B1 (de)
PT (1)	PT1652526E (de)
RU (1)	RU2302245C2 (de)
WO (1)	WO2003037354A1 (de)
ZA (1)	ZA200403088B (de)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US20050080061A1 (en) *	2003-07-23	2005-04-14	Corcept Therapeutics, Inc.	Antiglucocorticoid therapy for the prevention of neurological damage in premature infants
AU2011236053B2 (en) *	2004-11-19	2014-06-26	Merck Sharpe & Dohme B.V.	Drug combination comprising a selective serotonin reuptake inhibitor and a glucocorticoid receptor antagonist for the treatment of depression
CN101060860B (zh) *	2004-11-19	2013-07-17	Msd欧斯股份有限公司	用于治疗抑郁症的包含选择性5-羟色胺再摄取抑制剂和糖皮质激素受体拮抗剂的药物组合
EP2012796A4 (de) *	2006-05-02	2010-08-11	Corcept Therapeutics Inc	Verwendung eines glucocorticoidrezeptor-ii-antagonisten zur behandlung von depressionen bei mit il-2 behandelten patienten
US8658128B2 (en)	2011-02-03	2014-02-25	Pop Test Cortisol Llc	System and method for diagnosis and treatment
EP2699245A4 (de) *	2011-04-18	2014-12-10	Pop Test Cortisol Llc	Behandlung von haarausfall
US8986677B2 (en) *	2012-07-30	2015-03-24	Pop Test Cortisol Llc	Therapeutic compositions and methods

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4814333A (en) *	1987-07-28	1989-03-21	The Trustees Of Dartmouth College	Method for treatment of hypercortisolemic, depressed patients
DE4447401A1 (de) *	1994-12-23	1996-07-04	Schering Ag	14,17-C¶2¶-überbrückte Steroide
IL118974A (en) *	1995-08-17	2001-09-13	Akzo Nobel Nv	History 11 - (Transformed Phenyl) - Astra - 4, 9 - Diane, their preparation and pharmaceutical preparations containing them
DE19727772A1 (de) *	1997-06-30	1999-01-28	Forschungszentrum Juelich Gmbh	Magnetflußsensor mit ringförmiger Sonde
ATE332696T1 (de) *	1997-10-06	2006-08-15	Univ Leland Stanford Junior	Methode zur behandlung von durch glycocorticoidstörungen verursachten psychosen
CA2440605C (en) *	2001-03-23	2012-01-10	Corcept Therapeutics, Inc.	Methods for treating stress disorders using glucocorticoid receptor-specific antagonists
WO2002096433A1 (en) *	2001-05-04	2002-12-05	Corcept Therapeutics, Inc.	Methods for treating delirium using glucocorticoid receptor-specific antagonists
CA2459033C (en) *	2001-08-31	2012-05-22	Corcept Therapeutics, Inc.	Methods for inhibiting cognitive deterioration in adults with down's syndrome

2002
- 2002-10-21 KR KR1020047006050A patent/KR20050038580A/ko not_active Ceased
- 2002-10-21 RU RU2004116082/15A patent/RU2302245C2/ru not_active IP Right Cessation
- 2002-10-21 MX MXPA04003781A patent/MXPA04003781A/es active IP Right Grant
- 2002-10-21 PL PL369261A patent/PL206687B1/pl not_active IP Right Cessation
- 2002-10-21 WO PCT/EP2002/011732 patent/WO2003037354A1/en not_active Ceased
- 2002-10-21 IL IL16124802A patent/IL161248A0/xx unknown
- 2002-10-21 JP JP2003539697A patent/JP4647909B2/ja not_active Expired - Fee Related
- 2002-10-21 US US10/493,981 patent/US20040266863A1/en not_active Abandoned
- 2002-10-21 PT PT06101005T patent/PT1652526E/pt unknown
- 2002-10-21 CN CNB028210417A patent/CN100531738C/zh not_active Expired - Fee Related
- 2002-10-21 EP EP02781273A patent/EP1441739B1/de not_active Expired - Lifetime
- 2002-10-21 AT AT06101005T patent/ATE420649T1/de active
- 2002-10-21 DE DE60230936T patent/DE60230936D1/de not_active Expired - Lifetime
- 2002-10-21 EP EP06101005A patent/EP1652526B1/de not_active Expired - Lifetime
- 2002-10-21 HU HU0500070A patent/HUP0500070A3/hu unknown
- 2002-10-21 ES ES06101005T patent/ES2319563T3/es not_active Expired - Lifetime
- 2002-10-21 HR HRP20040370AA patent/HRP20040370B1/xx not_active IP Right Cessation
- 2002-10-21 BR BR0213466-7A patent/BR0213466A/pt not_active IP Right Cessation
- 2002-10-21 CA CA2463446A patent/CA2463446C/en not_active Expired - Fee Related
- 2002-10-21 AT AT02781273T patent/ATE317700T1/de active
- 2002-10-21 AU AU2002348996A patent/AU2002348996B2/en not_active Ceased
- 2002-10-21 DK DK06101005T patent/DK1652526T3/da active
- 2002-10-21 NZ NZ532429A patent/NZ532429A/en not_active IP Right Cessation
- 2002-10-21 DE DE60209248T patent/DE60209248D1/de not_active Expired - Lifetime
2004
- 2004-03-31 IS IS7204A patent/IS2702B/is unknown
- 2004-04-01 IL IL161248A patent/IL161248A/en not_active IP Right Cessation
- 2004-04-22 ZA ZA200403088A patent/ZA200403088B/en unknown
- 2004-04-23 NO NO20041651A patent/NO332978B1/no not_active IP Right Cessation
- 2004-04-23 EC EC2004005080A patent/ECSP045080A/es unknown
2009
- 2009-02-02 CY CY20091100116T patent/CY1110173T1/el unknown

Also Published As

Publication number	Publication date
CA2463446C (en)	2010-02-23
IS7204A (is)	2004-03-31
CY1110173T1 (el)	2015-01-14
PL206687B1 (pl)	2010-09-30
EP1441739A1 (de)	2004-08-04
ECSP045080A (es)	2004-06-28
EP1652526A3 (de)	2006-08-02
WO2003037354A1 (en)	2003-05-08
IL161248A (en)	2010-12-30
IS2702B (is)	2010-11-15
CN100531738C (zh)	2009-08-26
DE60230936D1 (de)	2009-03-05
MXPA04003781A (es)	2004-07-30
HUP0500070A3 (en)	2012-09-28
NO332978B1 (no)	2013-02-11
NO20041651L (no)	2004-04-23
RU2302245C2 (ru)	2007-07-10
HK1087357A1 (en)	2006-10-13
JP2005521637A (ja)	2005-07-21
DE60209248D1 (de)	2006-04-20
PT1652526E (pt)	2009-02-06
IL161248A0 (en)	2004-09-27
ZA200403088B (en)	2005-01-24
CN1582153A (zh)	2005-02-16
KR20050038580A (ko)	2005-04-27
EP1652526B1 (de)	2009-01-14
PL369261A1 (en)	2005-04-18
EP1652526A2 (de)	2006-05-03
NZ532429A (en)	2004-10-29
AU2002348996B2 (en)	2008-06-05
DK1652526T3 (da)	2009-05-18
RU2004116082A (ru)	2005-05-10
HRP20040370A2 (en)	2004-08-31
BR0213466A (pt)	2004-11-09
US20040266863A1 (en)	2004-12-30
CA2463446A1 (en)	2003-05-08
HRP20040370B1 (hr)	2012-09-30
ES2319563T3 (es)	2009-05-08
EP1441739B1 (de)	2006-02-15
HUP0500070A2 (hu)	2005-04-28
JP4647909B2 (ja)	2011-03-09
ATE420649T1 (de)	2009-01-15

Publication	Publication Date	Title
NO20042811L (no)	2004-07-05	Substituerte henzoksazoler og analoger som estrogene midler
BG104544A (en)	2001-03-30	Novel acylguanadine derivatives as inhibitors of bone resorption and as vitronectin receptor antagonists
ATE269336T1 (de)	2004-07-15	Steroidrezeptor-modulator verbindungen und methoden
ES2196063T3 (es)	2003-12-16	Utilizacion de agentes antagonistas competitivos de progesterona para la preparacion de medicamentos destinados al tratamiento de hemorragias uterinas disfuncionales.
ES2124905T3 (es)	1999-02-16	Esteroides antiglucocorticoides destinados al tratamiento de trastornos de ansiedad.
MXPA04005784A (es)	2004-09-13	2-fenilbenzofuranos sustituidos como agentes estrogenitos.
SE9902765D0 (sv)	1999-07-21	Novel compounds
CY1110173T1 (el)	2015-01-14	Χρηση της (11 beta, 17beta)-11-(1,3-benzodioxol-5-yl)-17-hydroxy-17-(1-propynyl)-estra-4,9-dien-3-one στη θεραπεια μειζωνος καταθλιπτικης διαταραχης
DE60115274D1 (de)	2005-12-29	Verwendung von antiprogestinen zur prophylaxe und behandlung von hormonabhängigen erkrankungen
BR0213684A (pt)	2004-10-26	Uso de antagonistas do receptor de endotelina para o tratamento de doenças tumorìgenas
NO20014855D0 (no)	2001-10-05	N-(2-fenyl-4-aminobutyl)-1-naftamider som neurokinin-1- reseptorantagonister
BR0207066A (pt)	2004-03-30	Derivados do 2h-1-benzopirano - processos para sua preparação e composições farmacêuticas a partir deles
DK1487859T3 (da)	2008-10-06	Fremstillingsmetoder til at fremstille Eplerenon
BG103060A (bg)	1999-10-29	19- нор- холан стероиди като неврохимични инициатори на промяната в действието на хипоталамуса причовек
NO20014961L (no)	2001-11-07	Integrin-reseptor-ligander
ATE419855T1 (de)	2009-01-15	Therapie für hormonersatz und depression enthaltend dienogest
AR018313A1 (es)	2001-11-14	Kit anticonceptivo que comprende medios para la administracion diaria de un agente anticonceptivo, uso de un compuesto esteroide que tiene un perfil deactividad que combina inherentemente las actividades progestagenicas y estrogenicas y un metodo anticonceptivo
NO20022712D0 (no)	2002-06-07	Umettede 14,15-syklopropanandrostaner, fremgangsmåte for deres fremstilling, og farmasöytiske preparater som inneholderdisse forbindelsene
NO974256L (no)	1997-11-14	Anvendelse av anti-östrogener som befruktningshindrende midler for menn
DK1090028T3 (da)	2002-04-29	Umættede 14,15-cyclopropano-androstaner, fremgangsmåde til deres fremstilling og farmaceutiske præparater indeholdende disse forbindelser