IS7204A - Notkun á (11ß, 17ß)-11-(1,3-bensódíoxól-5-ýl)-17-hýdroxý-17-(1-própýnýl)-estra-4,9-díen-3-ón við meðhöndlun á stórvægilegri geðlægðartruflun - Google Patents

Notkun á (11ß, 17ß)-11-(1,3-bensódíoxól-5-ýl)-17-hýdroxý-17-(1-própýnýl)-estra-4,9-díen-3-ón við meðhöndlun á stórvægilegri geðlægðartruflun

Info

Publication number: IS7204A
Authority: IS; Iceland
Prior art keywords: benzodioxol; propynyl; hydroxy; treatment; din
Prior art date: 2001-10-26

Application number

IS7204A

Other languages

English (en)

Other versions

IS2702B (is

Inventor

Sennef Cornelis

Wijnand Mathys Marie Peeters Bernardus

Original Assignee

Akzo Nobel N.V.

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2001-10-26

Filing date

2004-03-31

Publication date

2004-03-31

2004-03-31 Application filed by Akzo Nobel N.V. filed Critical Akzo Nobel N.V.

2004-03-31 Publication of IS7204A publication Critical patent/IS7204A/is

2010-11-15 Publication of IS2702B publication Critical patent/IS2702B/is

Links

-1 1,3-benzodioxol-5-yl Chemical group 0.000 title 1
125000000530 1-propynyl group Chemical group [H]C([H])([H])C#C* 0.000 title 1
208000024714 major depressive disease Diseases 0.000 title 1
DFELGYQKEOCHOA-BZAFBGKRSA-N (8s,11r,13s,14s,17s)-11-(1,3-benzodioxol-5-yl)-17-hydroxy-13-methyl-17-prop-1-ynyl-1,2,6,7,8,11,12,14,15,16-decahydrocyclopenta[a]phenanthren-3-one Chemical compound C1=C2OCOC2=CC([C@@H]2C3=C4CCC(=O)C=C4CC[C@H]3[C@@H]3CC[C@@]([C@]3(C2)C)(O)C#CC)=C1 DFELGYQKEOCHOA-BZAFBGKRSA-N 0.000 abstract 2
DBLOJPKZEOYNBN-SQNIBIBYSA-N (8s,13s,14s)-13-methyl-2,6,7,8,11,12,14,15,16,17-decahydro-1h-cyclopenta[a]phenanthren-3-one Chemical compound C1CC2=CC(=O)CCC2=C2[C@@H]1[C@@H]1CCC[C@@]1(C)CC2 DBLOJPKZEOYNBN-SQNIBIBYSA-N 0.000 abstract 1
208000020401 Depressive disease Diseases 0.000 abstract 1
239000003814 drug Substances 0.000 abstract 1
229940126013 glucocorticoid receptor antagonist Drugs 0.000 abstract 1
239000003850 glucocorticoid receptor antagonist Substances 0.000 abstract 1
239000000825 pharmaceutical preparation Substances 0.000 abstract 1
238000002360 preparation method Methods 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/58—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants

Landscapes

Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical & Material Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Epidemiology (AREA)
Neurology (AREA)
Bioinformatics & Cheminformatics (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Organic Chemistry (AREA)
Chemical Kinetics & Catalysis (AREA)
Neurosurgery (AREA)
Biomedical Technology (AREA)
General Chemical & Material Sciences (AREA)
Engineering & Computer Science (AREA)
Psychiatry (AREA)
Pain & Pain Management (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Steroid Compounds (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

IS7204A 2001-10-26 2004-03-31 Notkun á (11beta, 17beta)-11-(1,3-bensódíoxól-5-ýl)-17-hýdroxý-17-(1-própýnýl)-estra-4,9-díen-3-ón í meðhöndluninni á alvarlegri geðdeyfðartruflun IS2702B (is)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
EP01204072		2001-10-26
PCT/EP2002/011732 WO2003037354A1 (en)	2001-10-26	2002-10-21	USE OF (11β, 17β)-11-(1,3-BENZODIOXOL-5-YL)-17-HYDROXY-17-(1-PROPYNYL)-ESTRA-4,9-DIEN-3-ONE IN THE TREATMENT OF MAJOR DEPRESSIVE DISORDER

Publications (2)

Publication Number	Publication Date
IS7204A true IS7204A (is)	2004-03-31
IS2702B IS2702B (is)	2010-11-15

Family

ID=8181136

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
IS7204A IS2702B (is)	2001-10-26	2004-03-31	Notkun á (11beta, 17beta)-11-(1,3-bensódíoxól-5-ýl)-17-hýdroxý-17-(1-própýnýl)-estra-4,9-díen-3-ón í meðhöndluninni á alvarlegri geðdeyfðartruflun

Country Status (26)

Country	Link
US (1)	US20040266863A1 (is)
EP (2)	EP1441739B1 (is)
JP (1)	JP4647909B2 (is)
KR (1)	KR20050038580A (is)
CN (1)	CN100531738C (is)
AT (2)	ATE420649T1 (is)
AU (1)	AU2002348996B2 (is)
BR (1)	BR0213466A (is)
CA (1)	CA2463446C (is)
CY (1)	CY1110173T1 (is)
DE (2)	DE60209248D1 (is)
DK (1)	DK1652526T3 (is)
EC (1)	ECSP045080A (is)
ES (1)	ES2319563T3 (is)
HR (1)	HRP20040370B1 (is)
HU (1)	HUP0500070A3 (is)
IL (2)	IL161248A0 (is)
IS (1)	IS2702B (is)
MX (1)	MXPA04003781A (is)
NO (1)	NO332978B1 (is)
NZ (1)	NZ532429A (is)
PL (1)	PL206687B1 (is)
PT (1)	PT1652526E (is)
RU (1)	RU2302245C2 (is)
WO (1)	WO2003037354A1 (is)
ZA (1)	ZA200403088B (is)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US20050080061A1 (en) *	2003-07-23	2005-04-14	Corcept Therapeutics, Inc.	Antiglucocorticoid therapy for the prevention of neurological damage in premature infants
AU2011236053B2 (en) *	2004-11-19	2014-06-26	Merck Sharpe & Dohme B.V.	Drug combination comprising a selective serotonin reuptake inhibitor and a glucocorticoid receptor antagonist for the treatment of depression
CN101060860B (zh) *	2004-11-19	2013-07-17	Msd欧斯股份有限公司	用于治疗抑郁症的包含选择性5-羟色胺再摄取抑制剂和糖皮质激素受体拮抗剂的药物组合
AU2007248059A1 (en) *	2006-05-02	2007-11-15	Corcept Therapeutics, Inc.	The use of a glucocorticoid receptor ii antagonist to treat depression in patients taking il-2
EP2671086B1 (en) *	2011-02-03	2018-04-25	Pop Test Oncology LLC	System and method for diagnosis and treatment
EP2699245A4 (en) *	2011-04-18	2014-12-10	Pop Test Cortisol Llc	TREATMENT AGAINST HAIR LOSS
US8986677B2 (en) *	2012-07-30	2015-03-24	Pop Test Cortisol Llc	Therapeutic compositions and methods

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4814333A (en) *	1987-07-28	1989-03-21	The Trustees Of Dartmouth College	Method for treatment of hypercortisolemic, depressed patients
DE4447401A1 (de) *	1994-12-23	1996-07-04	Schering Ag	14,17-C¶2¶-überbrückte Steroide
IL118974A (en) *	1995-08-17	2001-09-13	Akzo Nobel Nv	History 11 - (Transformed Phenyl) - Astra - 4, 9 - Diane, their preparation and pharmaceutical preparations containing them
DE19727772A1 (de) *	1997-06-30	1999-01-28	Forschungszentrum Juelich Gmbh	Magnetflußsensor mit ringförmiger Sonde
CN1187053C (zh) *	1997-10-06	2005-02-02	利兰·斯坦福青年大学托管委员会	糖皮质素受体拮抗剂用于制造治疗精神病药物的用途
WO2002076390A2 (en) *	2001-03-23	2002-10-03	Corcept Therapeutics, Inc.	Methods for treating stress disorders using glucocorticoid receptor-specific antagonists
AU2002303652B2 (en) *	2001-05-04	2006-08-31	Corcept Therapeutics, Inc.	Methods for treating delirium using glucocorticoid receptor-specific antagonists
CN1556708A (zh) *	2001-08-31	2004-12-22	�Ƹ��	抑制成年唐氏综合症患者认知退化的方法

2002
- 2002-10-21 PT PT06101005T patent/PT1652526E/pt unknown
- 2002-10-21 ES ES06101005T patent/ES2319563T3/es not_active Expired - Lifetime
- 2002-10-21 EP EP02781273A patent/EP1441739B1/en not_active Expired - Lifetime
- 2002-10-21 MX MXPA04003781A patent/MXPA04003781A/es active IP Right Grant
- 2002-10-21 CN CNB028210417A patent/CN100531738C/zh not_active Expired - Fee Related
- 2002-10-21 HR HRP20040370AA patent/HRP20040370B1/xx not_active IP Right Cessation
- 2002-10-21 CA CA2463446A patent/CA2463446C/en not_active Expired - Fee Related
- 2002-10-21 HU HU0500070A patent/HUP0500070A3/hu unknown
- 2002-10-21 AU AU2002348996A patent/AU2002348996B2/en not_active Ceased
- 2002-10-21 AT AT06101005T patent/ATE420649T1/de active
- 2002-10-21 WO PCT/EP2002/011732 patent/WO2003037354A1/en not_active Ceased
- 2002-10-21 DE DE60209248T patent/DE60209248D1/de not_active Expired - Lifetime
- 2002-10-21 EP EP06101005A patent/EP1652526B1/en not_active Expired - Lifetime
- 2002-10-21 JP JP2003539697A patent/JP4647909B2/ja not_active Expired - Fee Related
- 2002-10-21 AT AT02781273T patent/ATE317700T1/de active
- 2002-10-21 RU RU2004116082/15A patent/RU2302245C2/ru not_active IP Right Cessation
- 2002-10-21 PL PL369261A patent/PL206687B1/pl not_active IP Right Cessation
- 2002-10-21 NZ NZ532429A patent/NZ532429A/en not_active IP Right Cessation
- 2002-10-21 DE DE60230936T patent/DE60230936D1/de not_active Expired - Lifetime
- 2002-10-21 BR BR0213466-7A patent/BR0213466A/pt not_active IP Right Cessation
- 2002-10-21 US US10/493,981 patent/US20040266863A1/en not_active Abandoned
- 2002-10-21 KR KR1020047006050A patent/KR20050038580A/ko not_active Ceased
- 2002-10-21 IL IL16124802A patent/IL161248A0/xx unknown
- 2002-10-21 DK DK06101005T patent/DK1652526T3/da active
2004
- 2004-03-31 IS IS7204A patent/IS2702B/is unknown
- 2004-04-01 IL IL161248A patent/IL161248A/en not_active IP Right Cessation
- 2004-04-22 ZA ZA200403088A patent/ZA200403088B/en unknown
- 2004-04-23 EC EC2004005080A patent/ECSP045080A/es unknown
- 2004-04-23 NO NO20041651A patent/NO332978B1/no not_active IP Right Cessation
2009
- 2009-02-02 CY CY20091100116T patent/CY1110173T1/el unknown

Also Published As

Publication number	Publication date
EP1652526A3 (en)	2006-08-02
JP2005521637A (ja)	2005-07-21
HUP0500070A3 (en)	2012-09-28
NO332978B1 (no)	2013-02-11
EP1652526A2 (en)	2006-05-03
CN1582153A (zh)	2005-02-16
EP1441739A1 (en)	2004-08-04
IS2702B (is)	2010-11-15
PL369261A1 (en)	2005-04-18
HUP0500070A2 (hu)	2005-04-28
DE60230936D1 (de)	2009-03-05
RU2004116082A (ru)	2005-05-10
CA2463446C (en)	2010-02-23
NZ532429A (en)	2004-10-29
DK1652526T3 (da)	2009-05-18
ECSP045080A (es)	2004-06-28
EP1441739B1 (en)	2006-02-15
BR0213466A (pt)	2004-11-09
CY1110173T1 (el)	2015-01-14
JP4647909B2 (ja)	2011-03-09
WO2003037354A1 (en)	2003-05-08
PL206687B1 (pl)	2010-09-30
ATE317700T1 (de)	2006-03-15
AU2002348996B2 (en)	2008-06-05
HK1087357A1 (en)	2006-10-13
MXPA04003781A (es)	2004-07-30
CN100531738C (zh)	2009-08-26
EP1652526B1 (en)	2009-01-14
HRP20040370A2 (en)	2004-08-31
ES2319563T3 (es)	2009-05-08
PT1652526E (pt)	2009-02-06
IL161248A0 (en)	2004-09-27
HRP20040370B1 (hr)	2012-09-30
US20040266863A1 (en)	2004-12-30
ZA200403088B (en)	2005-01-24
CA2463446A1 (en)	2003-05-08
IL161248A (en)	2010-12-30
ATE420649T1 (de)	2009-01-15
NO20041651L (no)	2004-04-23
RU2302245C2 (ru)	2007-07-10
DE60209248D1 (de)	2006-04-20
KR20050038580A (ko)	2005-04-27

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