DK1652526T3 - Anvendelse af (11beta, 17beta)-11-(1,3-benzodioxol-5-yl)-17-hydroxy-17-(1-propynyl)-estra-4,9-dien-3-on i behandling af svær depressionslidelse - Google Patents

Anvendelse af (11beta, 17beta)-11-(1,3-benzodioxol-5-yl)-17-hydroxy-17-(1-propynyl)-estra-4,9-dien-3-on i behandling af svær depressionslidelse

Info

Publication number: DK1652526T3
Authority: DK; Denmark
Prior art keywords: estra; benzodioxol; dien; propynyl; hydroxy
Prior art date: 2001-10-26

Application number

DK06101005T

Other languages

English (en)

Inventor

Cornelis Sennef

B W M M Bernardus Peeters

Original Assignee

Organon Nv

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2001-10-26

Filing date

2002-10-21

Publication date

2009-05-18

2002-10-21 Application filed by Organon Nv filed Critical Organon Nv

2009-05-18 Application granted granted Critical

2009-05-18 Publication of DK1652526T3 publication Critical patent/DK1652526T3/da

Links

DFELGYQKEOCHOA-BZAFBGKRSA-N (8s,11r,13s,14s,17s)-11-(1,3-benzodioxol-5-yl)-17-hydroxy-13-methyl-17-prop-1-ynyl-1,2,6,7,8,11,12,14,15,16-decahydrocyclopenta[a]phenanthren-3-one Chemical compound C1=C2OCOC2=CC([C@@H]2C3=C4CCC(=O)C=C4CC[C@H]3[C@@H]3CC[C@@]([C@]3(C2)C)(O)C#CC)=C1 DFELGYQKEOCHOA-BZAFBGKRSA-N 0.000 abstract 2
DBLOJPKZEOYNBN-SQNIBIBYSA-N (8s,13s,14s)-13-methyl-2,6,7,8,11,12,14,15,16,17-decahydro-1h-cyclopenta[a]phenanthren-3-one Chemical compound C1CC2=CC(=O)CCC2=C2[C@@H]1[C@@H]1CCC[C@@]1(C)CC2 DBLOJPKZEOYNBN-SQNIBIBYSA-N 0.000 abstract 1
208000020401 Depressive disease Diseases 0.000 abstract 1
239000003814 drug Substances 0.000 abstract 1
229940126013 glucocorticoid receptor antagonist Drugs 0.000 abstract 1
239000003850 glucocorticoid receptor antagonist Substances 0.000 abstract 1
239000000825 pharmaceutical preparation Substances 0.000 abstract 1
238000002360 preparation method Methods 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/58—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Epidemiology (AREA)
Engineering & Computer Science (AREA)
Chemical Kinetics & Catalysis (AREA)
Pain & Pain Management (AREA)
Bioinformatics & Cheminformatics (AREA)
Biomedical Technology (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Psychiatry (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Organic Chemistry (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Steroid Compounds (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

DK06101005T 2001-10-26 2002-10-21 Anvendelse af (11beta, 17beta)-11-(1,3-benzodioxol-5-yl)-17-hydroxy-17-(1-propynyl)-estra-4,9-dien-3-on i behandling af svær depressionslidelse DK1652526T3 (da)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
EP01204072		2001-10-26
PCT/EP2002/011732 WO2003037354A1 (en)	2001-10-26	2002-10-21	USE OF (11β, 17β)-11-(1,3-BENZODIOXOL-5-YL)-17-HYDROXY-17-(1-PROPYNYL)-ESTRA-4,9-DIEN-3-ONE IN THE TREATMENT OF MAJOR DEPRESSIVE DISORDER

Publications (1)

Publication Number	Publication Date
DK1652526T3 true DK1652526T3 (da)	2009-05-18

Family

ID=8181136

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK06101005T DK1652526T3 (da)	2001-10-26	2002-10-21	Anvendelse af (11beta, 17beta)-11-(1,3-benzodioxol-5-yl)-17-hydroxy-17-(1-propynyl)-estra-4,9-dien-3-on i behandling af svær depressionslidelse

Country Status (26)

Country	Link
US (1)	US20040266863A1 (da)
EP (2)	EP1652526B1 (da)
JP (1)	JP4647909B2 (da)
KR (1)	KR20050038580A (da)
CN (1)	CN100531738C (da)
AT (2)	ATE420649T1 (da)
AU (1)	AU2002348996B2 (da)
BR (1)	BR0213466A (da)
CA (1)	CA2463446C (da)
CY (1)	CY1110173T1 (da)
DE (2)	DE60209248D1 (da)
DK (1)	DK1652526T3 (da)
EC (1)	ECSP045080A (da)
ES (1)	ES2319563T3 (da)
HR (1)	HRP20040370B1 (da)
HU (1)	HUP0500070A3 (da)
IL (2)	IL161248A0 (da)
IS (1)	IS2702B (da)
MX (1)	MXPA04003781A (da)
NO (1)	NO332978B1 (da)
NZ (1)	NZ532429A (da)
PL (1)	PL206687B1 (da)
PT (1)	PT1652526E (da)
RU (1)	RU2302245C2 (da)
WO (1)	WO2003037354A1 (da)
ZA (1)	ZA200403088B (da)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US20050080061A1 (en) *	2003-07-23	2005-04-14	Corcept Therapeutics, Inc.	Antiglucocorticoid therapy for the prevention of neurological damage in premature infants
AU2011236053B2 (en) *	2004-11-19	2014-06-26	Merck Sharpe & Dohme B.V.	Drug combination comprising a selective serotonin reuptake inhibitor and a glucocorticoid receptor antagonist for the treatment of depression
CA2585317C (en) *	2004-11-19	2015-02-24	N.V. Organon	Drug combination for the treatment of depression and related disorders comprising a selective serotonin reuptake inhibitor
JP2009535430A (ja) *	2006-05-02	2009-10-01	コーセプトセラピューティクス，インコーポレイテッド	Ｉｌ−２を摂取している患者における抑うつを処置するためのグルココルチコイドレセプターｉｉアンタゴニストの使用
US8658128B2 (en) *	2011-02-03	2014-02-25	Pop Test Cortisol Llc	System and method for diagnosis and treatment
WO2012145258A1 (en) *	2011-04-18	2012-10-26	Pop Test Cortisol Llc	Hair loss treatment
US8986677B2 (en) *	2012-07-30	2015-03-24	Pop Test Cortisol Llc	Therapeutic compositions and methods

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4814333A (en) *	1987-07-28	1989-03-21	The Trustees Of Dartmouth College	Method for treatment of hypercortisolemic, depressed patients
DE4447401A1 (de) *	1994-12-23	1996-07-04	Schering Ag	14,17-C¶2¶-überbrückte Steroide
IL118974A (en) *	1995-08-17	2001-09-13	Akzo Nobel Nv	History 11 - (Transformed Phenyl) - Astra - 4, 9 - Diane, their preparation and pharmaceutical preparations containing them
DE19727772A1 (de) *	1997-06-30	1999-01-28	Forschungszentrum Juelich Gmbh	Magnetflußsensor mit ringförmiger Sonde
AU747956B2 (en) *	1997-10-06	2002-05-30	Board Of Trustees Of The Leland Stanford Junior University	Methods for treating psychosis associated with glucocorticoid related dysfunction
JP2004525135A (ja) *	2001-03-23	2004-08-19	コーセプトセラピューティクス，インコーポレイテッド	糖質コルチコイドレセプター特異的アンタゴニストを使用するストレス障害を処置するための方法
ATE492281T1 (de) *	2001-05-04	2011-01-15	Corcept Therapeutics Inc	Verwendung von glucocorticoid-rezeptor- spezifischen antagonisten zur behandlung von delirium
ATE411013T1 (de) *	2001-08-31	2008-10-15	Corcept Therapeutics Inc	Verfahren zur hemmung der verschlechterung der kognitiven leistungsfähigkeit bei erwachsenen mit down-syndrom

2002
- 2002-10-21 CN CNB028210417A patent/CN100531738C/zh not_active Expired - Fee Related
- 2002-10-21 PT PT06101005T patent/PT1652526E/pt unknown
- 2002-10-21 WO PCT/EP2002/011732 patent/WO2003037354A1/en not_active Ceased
- 2002-10-21 NZ NZ532429A patent/NZ532429A/en not_active IP Right Cessation
- 2002-10-21 BR BR0213466-7A patent/BR0213466A/pt not_active IP Right Cessation
- 2002-10-21 DE DE60209248T patent/DE60209248D1/de not_active Expired - Lifetime
- 2002-10-21 KR KR1020047006050A patent/KR20050038580A/ko not_active Ceased
- 2002-10-21 PL PL369261A patent/PL206687B1/pl not_active IP Right Cessation
- 2002-10-21 US US10/493,981 patent/US20040266863A1/en not_active Abandoned
- 2002-10-21 HU HU0500070A patent/HUP0500070A3/hu unknown
- 2002-10-21 ES ES06101005T patent/ES2319563T3/es not_active Expired - Lifetime
- 2002-10-21 EP EP06101005A patent/EP1652526B1/en not_active Expired - Lifetime
- 2002-10-21 DK DK06101005T patent/DK1652526T3/da active
- 2002-10-21 EP EP02781273A patent/EP1441739B1/en not_active Expired - Lifetime
- 2002-10-21 JP JP2003539697A patent/JP4647909B2/ja not_active Expired - Fee Related
- 2002-10-21 AU AU2002348996A patent/AU2002348996B2/en not_active Ceased
- 2002-10-21 HR HRP20040370AA patent/HRP20040370B1/xx not_active IP Right Cessation
- 2002-10-21 AT AT06101005T patent/ATE420649T1/de active
- 2002-10-21 MX MXPA04003781A patent/MXPA04003781A/es active IP Right Grant
- 2002-10-21 AT AT02781273T patent/ATE317700T1/de active
- 2002-10-21 RU RU2004116082/15A patent/RU2302245C2/ru not_active IP Right Cessation
- 2002-10-21 IL IL16124802A patent/IL161248A0/xx unknown
- 2002-10-21 DE DE60230936T patent/DE60230936D1/de not_active Expired - Lifetime
- 2002-10-21 CA CA2463446A patent/CA2463446C/en not_active Expired - Fee Related
2004
- 2004-03-31 IS IS7204A patent/IS2702B/is unknown
- 2004-04-01 IL IL161248A patent/IL161248A/en not_active IP Right Cessation
- 2004-04-22 ZA ZA200403088A patent/ZA200403088B/en unknown
- 2004-04-23 NO NO20041651A patent/NO332978B1/no not_active IP Right Cessation
- 2004-04-23 EC EC2004005080A patent/ECSP045080A/es unknown
2009
- 2009-02-02 CY CY20091100116T patent/CY1110173T1/el unknown

Also Published As

Publication number	Publication date
ZA200403088B (en)	2005-01-24
HUP0500070A2 (hu)	2005-04-28
RU2004116082A (ru)	2005-05-10
IL161248A (en)	2010-12-30
EP1652526A2 (en)	2006-05-03
EP1441739B1 (en)	2006-02-15
DE60209248D1 (de)	2006-04-20
IL161248A0 (en)	2004-09-27
AU2002348996B2 (en)	2008-06-05
IS7204A (is)	2004-03-31
ECSP045080A (es)	2004-06-28
WO2003037354A1 (en)	2003-05-08
KR20050038580A (ko)	2005-04-27
HRP20040370B1 (hr)	2012-09-30
JP4647909B2 (ja)	2011-03-09
NZ532429A (en)	2004-10-29
MXPA04003781A (es)	2004-07-30
CN1582153A (zh)	2005-02-16
HK1087357A1 (en)	2006-10-13
ATE420649T1 (de)	2009-01-15
ES2319563T3 (es)	2009-05-08
DE60230936D1 (de)	2009-03-05
EP1652526A3 (en)	2006-08-02
PL206687B1 (pl)	2010-09-30
PL369261A1 (en)	2005-04-18
EP1652526B1 (en)	2009-01-14
HRP20040370A2 (en)	2004-08-31
US20040266863A1 (en)	2004-12-30
HUP0500070A3 (en)	2012-09-28
JP2005521637A (ja)	2005-07-21
NO20041651L (no)	2004-04-23
RU2302245C2 (ru)	2007-07-10
CY1110173T1 (el)	2015-01-14
EP1441739A1 (en)	2004-08-04
CA2463446A1 (en)	2003-05-08
CA2463446C (en)	2010-02-23
ATE317700T1 (de)	2006-03-15
PT1652526E (pt)	2009-02-06
NO332978B1 (no)	2013-02-11
CN100531738C (zh)	2009-08-26
IS2702B (is)	2010-11-15
BR0213466A (pt)	2004-11-09

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