ATE318821T1 - Pyranoindazole und ihre verwendung in der glaukombehandlung - Google Patents

Pyranoindazole und ihre verwendung in der glaukombehandlung

Info

Publication number
ATE318821T1
ATE318821T1 AT02734575T AT02734575T ATE318821T1 AT E318821 T1 ATE318821 T1 AT E318821T1 AT 02734575 T AT02734575 T AT 02734575T AT 02734575 T AT02734575 T AT 02734575T AT E318821 T1 ATE318821 T1 AT E318821T1
Authority
AT
Austria
Prior art keywords
pyranoindazoles
glaucoma treatment
glaucoma
treatment
Prior art date
Application number
AT02734575T
Other languages
English (en)
Inventor
Hwang-Hsing Chen
Jesse A May
Bryon S Severns
Original Assignee
Alcon Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Alcon Inc filed Critical Alcon Inc
Application granted granted Critical
Publication of ATE318821T1 publication Critical patent/ATE318821T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/04—Ortho-condensed systems
    • C07D491/044—Ortho-condensed systems with only one oxygen atom as ring hetero atom in the oxygen-containing ring
    • C07D491/052—Ortho-condensed systems with only one oxygen atom as ring hetero atom in the oxygen-containing ring the oxygen-containing ring being six-membered
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/06—Antiglaucoma agents or miotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Ophthalmology & Optometry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
AT02734575T 2001-06-01 2002-05-30 Pyranoindazole und ihre verwendung in der glaukombehandlung ATE318821T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US29542901P 2001-06-01 2001-06-01

Publications (1)

Publication Number Publication Date
ATE318821T1 true ATE318821T1 (de) 2006-03-15

Family

ID=23137684

Family Applications (1)

Application Number Title Priority Date Filing Date
AT02734575T ATE318821T1 (de) 2001-06-01 2002-05-30 Pyranoindazole und ihre verwendung in der glaukombehandlung

Country Status (19)

Country Link
US (2) US6696476B2 (de)
EP (1) EP1392292B1 (de)
JP (1) JP2004535418A (de)
KR (1) KR100626255B1 (de)
CN (1) CN100384417C (de)
AR (1) AR036044A1 (de)
AT (1) ATE318821T1 (de)
AU (1) AU2002305732B2 (de)
BR (1) BR0210241A (de)
CA (1) CA2447480A1 (de)
DE (1) DE60209486T2 (de)
DK (1) DK1392292T3 (de)
ES (1) ES2258631T3 (de)
MX (1) MXPA03010807A (de)
PL (1) PL366636A1 (de)
PT (1) PT1392292E (de)
RU (1) RU2273641C2 (de)
WO (1) WO2002098350A2 (de)
ZA (1) ZA200309034B (de)

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US6903081B2 (en) * 2000-03-31 2005-06-07 Purdue Research Foundation Phosphoramidates and methods therefor
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TW593302B (en) 2001-12-20 2004-06-21 Alcon Inc Novel benzodifuranimidazoline and benzofuranimidazoline derivatives and their use for the treatment of glaucoma
AU2002360819A1 (en) * 2001-12-28 2003-07-24 Bayer Corporation Cyclohexano- and cycloheptapyrazole derivative compounds, for use in diseases associated with the 5-ht2c receptor
JP2006501245A (ja) * 2002-08-30 2006-01-12 アルコン，インコーポレイテッド 置換された５−クロマン−５−イル−エチルアミン化合物および緑内障の治療のためのその使用
BR0316775A (pt) 2002-12-13 2005-11-01 Alcon Inc Novos análogos de benzopirano e seu uso para o tratamento de glaucoma
AU2004271978B2 (en) * 2003-09-04 2009-02-05 Merck & Co., Inc. Ophthalmic compositions for treating ocular hypertension
US7476687B2 (en) * 2003-11-26 2009-01-13 Alcon, Inc. Substituted furo[2,3-g]indazoles for the treatment of glaucoma
US7338972B1 (en) 2003-12-15 2008-03-04 Alcon, Inc. Substituted 1-alkylamino-1H-indazoles for the treatment of glaucoma
TW200520760A (en) 2003-12-15 2005-07-01 Alcon Inc Substituted [1,4] oxazino [2,3-g] indazoles for the treatment of glaucoma
US7129257B1 (en) * 2003-12-15 2006-10-31 Alcon, Inc. Pyrazolo[3,4- e]benzoxazoles for the treatment of glaucoma
EP2248524A3 (de) 2004-08-25 2011-03-09 Takeda Pharmaceutical Company Limited Mittel zur prävention/behandlung von stressbedingter harninkontinenz und vorsorgeuntersuchungsverfahren dafür
US20060073172A1 (en) * 2004-10-01 2006-04-06 Schneider L W Stabilized ophthalmic solution for the treatment of glaucoma and lowering intraocular pressure
US7425572B2 (en) 2004-12-08 2008-09-16 Alcon, Inc. Use of dioxindoindazoles and dioxoloindazoles for treating glaucoma
TW200744567A (en) * 2005-09-23 2007-12-16 Alcon Inc Phenylethylamine analogs and their use for treating glaucoma
EP2742936A1 (de) 2006-05-16 2014-06-18 Takeda Pharmaceutical Company Limited Kondensierte heterocyclische Verbindung und ihre Verwendung
US20070293475A1 (en) * 2006-06-20 2007-12-20 Alcon Manufacturing Ltd. Aryl and heteroaryl tetrahydrobenzazepine derivatives and their use for treating glaucoma
BRPI0714782A2 (pt) * 2006-07-31 2013-07-16 Senju Pharma Co preparaÇço lÍquida aquosa contendo composto de amida
WO2008016993A1 (en) * 2006-08-01 2008-02-07 Alcon Research, Ltd. Intermediates and methods for serotonergic agonist synthesis
WO2008016989A1 (en) * 2006-08-01 2008-02-07 Alcon Research, Ltd. Process for preparing pyranoindazole serotonergic receptor agonists
US20080058533A1 (en) * 2006-08-31 2008-03-06 Alcon, Inc. Pyranoindazole cyclic carbonates and methods of use
EP2789338A3 (de) 2007-11-15 2015-01-14 Takeda Pharmaceutical Company Limited Kondensiertes Pyridinderivat und seine Verwendung
JPWO2011071136A1 (ja) 2009-12-11 2013-04-22 アステラス製薬株式会社 線維筋痛症治療剤
JP6232142B2 (ja) * 2015-03-05 2017-11-15 株式会社ブリヂストン ゴム組成物、ジエン系重合体の製造方法及びタイヤ
TW201815766A (zh) 2016-09-22 2018-05-01 美商普雷辛肯公司 用於ｉｄｏ及ｔｄｏ調節之化合物及方法以及其適應症
EP3733204A4 (de) 2017-12-27 2021-09-15 Takeda Pharmaceutical Company Limited Therapeutikum für belastungsinkontinenz und stuhlinkontinenz
AU2019239952A1 (en) 2018-03-20 2020-10-08 Plexxikon Inc. Compounds and methods for IDO and TDO modulation, and indications therefor

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Also Published As

Publication number Publication date
CA2447480A1 (en) 2002-12-12
PL366636A1 (en) 2005-02-07
DE60209486D1 (de) 2006-04-27
MXPA03010807A (es) 2004-11-22
US20040106609A1 (en) 2004-06-03
DE60209486T2 (de) 2006-08-03
RU2003137825A (ru) 2005-04-20
KR20040010669A (ko) 2004-01-31
AR036044A1 (es) 2004-08-04
PT1392292E (pt) 2006-05-31
AU2002305732B2 (en) 2007-02-01
CN1592619A (zh) 2005-03-09
EP1392292A4 (de) 2004-08-11
JP2004535418A (ja) 2004-11-25
RU2273641C2 (ru) 2006-04-10
DK1392292T3 (da) 2006-05-29
CN100384417C (zh) 2008-04-30
WO2002098350A3 (en) 2003-02-27
HK1061212A1 (en) 2004-09-10
EP1392292A2 (de) 2004-03-03
US6881749B2 (en) 2005-04-19
ES2258631T3 (es) 2006-09-01
BR0210241A (pt) 2004-08-10
EP1392292B1 (de) 2006-03-01
ZA200309034B (en) 2004-07-16
US6696476B2 (en) 2004-02-24
US20030171418A1 (en) 2003-09-11
KR100626255B1 (ko) 2006-09-21
WO2002098350A2 (en) 2002-12-12

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