ATE318934T1 - Verfahren zum nachweis von ki-ras mutationen - Google Patents

Verfahren zum nachweis von ki-ras mutationen

Info

Publication number
ATE318934T1
ATE318934T1 AT03020560T AT03020560T ATE318934T1 AT E318934 T1 ATE318934 T1 AT E318934T1 AT 03020560 T AT03020560 T AT 03020560T AT 03020560 T AT03020560 T AT 03020560T AT E318934 T1 ATE318934 T1 AT E318934T1
Authority
AT
Austria
Prior art keywords
detecting
ras mutations
pcr
tissue
allele specific
Prior art date
Application number
AT03020560T
Other languages
English (en)
Inventor
Dagfinn Ogreid
Arve Ulvik
Jan Jacob Koornstra
Original Assignee
Nordiag As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nordiag As filed Critical Nordiag As
Application granted granted Critical
Publication of ATE318934T1 publication Critical patent/ATE318934T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/118—Prognosis of disease development
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/156—Polymorphic or mutational markers

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Analytical Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Pathology (AREA)
  • Genetics & Genomics (AREA)
  • Immunology (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Hospice & Palliative Care (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Oncology (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Analysing Materials By The Use Of Radiation (AREA)
  • Diaphragms For Electromechanical Transducers (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Investigating Or Analyzing Non-Biological Materials By The Use Of Chemical Means (AREA)
  • Control And Other Processes For Unpacking Of Materials (AREA)
  • Electrophonic Musical Instruments (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Electrically Operated Instructional Devices (AREA)
  • Saccharide Compounds (AREA)
  • Holo Graphy (AREA)
AT03020560T 1995-11-17 1996-11-15 Verfahren zum nachweis von ki-ras mutationen ATE318934T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
NO954667A NO954667D0 (no) 1995-11-17 1995-11-17 Fremgangsmåte til deteksjon av Ki-ras mutasjoner

Publications (1)

Publication Number Publication Date
ATE318934T1 true ATE318934T1 (de) 2006-03-15

Family

ID=19898772

Family Applications (2)

Application Number Title Priority Date Filing Date
AT96939373T ATE251222T1 (de) 1995-11-17 1996-11-15 Verfahren zur bestimung von ki-ras mutationen und dieses leistender testsatz
AT03020560T ATE318934T1 (de) 1995-11-17 1996-11-15 Verfahren zum nachweis von ki-ras mutationen

Family Applications Before (1)

Application Number Title Priority Date Filing Date
AT96939373T ATE251222T1 (de) 1995-11-17 1996-11-15 Verfahren zur bestimung von ki-ras mutationen und dieses leistender testsatz

Country Status (12)

Country Link
US (1) US6440661B1 (de)
EP (2) EP0868529B1 (de)
JP (1) JP2000500346A (de)
AT (2) ATE251222T1 (de)
AU (1) AU723980C (de)
DE (2) DE69630234T2 (de)
DK (2) DK0868529T3 (de)
ES (2) ES2262930T3 (de)
NO (2) NO954667D0 (de)
NZ (1) NZ322619A (de)
PT (2) PT868529E (de)
WO (1) WO1997019191A1 (de)

Families Citing this family (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9715034D0 (en) * 1997-07-18 1997-09-24 Zeneca Ltd Assay
EP1169479B1 (de) * 1999-04-09 2006-06-28 EXACT Sciences Corporation Verfahren zur detektion von nukleinsäuren, welche auf krebs hinweisen
US6531302B1 (en) * 1999-04-12 2003-03-11 Nanogen/Becton Dickinson Partnership Anchored strand displacement amplification on an electronically addressable microchip
US6849403B1 (en) 1999-09-08 2005-02-01 Exact Sciences Corporation Apparatus and method for drug screening
US6586177B1 (en) 1999-09-08 2003-07-01 Exact Sciences Corporation Methods for disease detection
CA2394921A1 (en) 1999-12-07 2001-06-14 Anthony P. Shuber Supracolonic aerodigestive neoplasm detection
US7087414B2 (en) 2000-06-06 2006-08-08 Applera Corporation Methods and devices for multiplexing amplification reactions
US6605451B1 (en) * 2000-06-06 2003-08-12 Xtrana, Inc. Methods and devices for multiplexing amplification reactions
EP2351853A1 (de) * 2000-06-06 2011-08-03 Life Technologies Corporation Methode und Vorrichtungen für multiplex Amplifizierungsreaktionen
US7482116B2 (en) 2002-06-07 2009-01-27 Dna Genotek Inc. Compositions and methods for obtaining nucleic acids from sputum
EP2031070B1 (de) 2002-12-04 2013-07-17 Life Technologies Corporation Multiplexverstärkung von Polynucleotiden
WO2005113769A1 (en) * 2004-05-14 2005-12-01 Exact Sciences Corporation Method for stabilizing biological samples for nucleic acid analysis
US20070134709A1 (en) * 2005-12-14 2007-06-14 Xiping Xu Usages of MTHFR gene polymorphisms in predicting homocysteine level, disease risk, and treatment effects and related methods and kit
GB2435512A (en) 2006-02-23 2007-08-29 Mologic Ltd A binding assay and assay device
CN103424541B (zh) 2006-05-18 2018-01-30 分子压型学会股份有限公司 确定针对病状的个性化医疗介入的系统和方法
US8768629B2 (en) 2009-02-11 2014-07-01 Caris Mpi, Inc. Molecular profiling of tumors
WO2010028288A2 (en) 2008-09-05 2010-03-11 Aueon, Inc. Methods for stratifying and annotating cancer drug treatment options
WO2010056337A2 (en) 2008-11-12 2010-05-20 Caris Mpi, Inc. Methods and systems of using exosomes for determining phenotypes
WO2011082321A1 (en) * 2009-12-31 2011-07-07 Van Andel Research Institute Methods for diagnosing the malignant potential of pancreatic cystic lesions
EP2542696B1 (de) 2010-03-01 2016-09-28 Caris Life Sciences Switzerland Holdings GmbH Theranostik-biomarker
JP2013526852A (ja) 2010-04-06 2013-06-27 カリス ライフ サイエンシズ ルクセンブルク ホールディングス 疾患に対する循環バイオマーカー
EP2619329B1 (de) 2010-09-24 2019-05-22 The Board of Trustees of The Leland Stanford Junior University Direkte erfassung, amplifikation und sequenzierung einer ziel-dna unter verwendung immobilisierter primer
GB201107466D0 (en) 2011-05-05 2011-06-15 Loktionov Alexandre Device and method for non-invasive collection of colorectal mucocellular layer and disease detection
CN102796811B (zh) * 2011-05-26 2013-12-18 上海赛安生物医药科技有限公司 检测kras突变的试剂及方法
WO2012177656A2 (en) 2011-06-19 2012-12-27 Abogen, Inc. Devices, solutions and methods for sample collection
JP5947392B2 (ja) * 2011-11-17 2016-07-06 ザ ジョンズ ホプキンス ユニバーシティー 膵嚢胞の鑑別
SG11201504241QA (en) * 2012-11-30 2015-06-29 Applied Proteomics Inc Method for evaluation of presence of or risk of colon tumors
KR102392407B1 (ko) 2014-03-07 2022-04-29 디엔에이 제노텍 인코퍼레이티드 생물학적 샘플에서 핵산을 안정화하기 위한 조성물 및 방법
WO2016164815A1 (en) 2015-04-10 2016-10-13 Applied Proteomics, Inc. Protein biomarker panels for detecting colorectal cancer and advanced adenoma
US10753936B2 (en) 2016-07-22 2020-08-25 Van Andel Research Institute Method of detecting the level of a glycan
MX2020014243A (es) 2018-06-19 2021-05-12 Biontech Us Inc Neoantigenos y usos de los mismos.

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4871838A (en) * 1985-07-23 1989-10-03 The Board Of Rijks Universiteit Leiden Probes and methods for detecting activated ras oncogenes
US5137806A (en) * 1989-12-11 1992-08-11 Board Of Regents, The University Of Texas System Methods and compositions for the detection of sequences in selected DNA molecules
IL97222A (en) * 1990-02-16 1995-08-31 Orion Yhtymae Oy Method and reagent for determining specific nucleotide variations
JP3633932B2 (ja) 1992-04-01 2005-03-30 ザ ジョーンズ ホプキンズ ユニバーシティー スクール オブ メディシン 糞便試料から単離した哺乳類の核酸を検出する方法、およびその検出用試薬
ATE198358T1 (de) * 1992-04-27 2001-01-15 Dartmouth College Detektion von gensequenzen in biologischen flüssigkeiten
JPH06167492A (ja) * 1992-11-30 1994-06-14 Otsuka Pharmaceut Co Ltd 変異癌遺伝子の検出測定方法
DE19512369A1 (de) * 1995-04-01 1996-10-02 Boehringer Mannheim Gmbh Vorrichtung zur Isolierung von Nukleinsäuren

Also Published As

Publication number Publication date
PT1394272E (pt) 2006-07-31
DE69635848D1 (de) 2006-04-27
DE69630234T2 (de) 2004-08-19
ES2262930T3 (es) 2006-12-01
AU723980C (en) 2002-10-24
DE69635848T2 (de) 2006-11-30
NO982246D0 (no) 1998-05-15
NO954667D0 (no) 1995-11-17
NO982246L (no) 1998-07-07
EP1394272A1 (de) 2004-03-03
US6440661B1 (en) 2002-08-27
ES2208766T3 (es) 2004-06-16
DK1394272T3 (da) 2006-07-03
WO1997019191A1 (en) 1997-05-29
NZ322619A (en) 1999-04-29
PT868529E (pt) 2004-02-27
EP1394272B1 (de) 2006-03-01
DE69630234D1 (de) 2003-11-06
JP2000500346A (ja) 2000-01-18
AU7656996A (en) 1997-06-11
EP0868529A1 (de) 1998-10-07
ATE251222T1 (de) 2003-10-15
AU723980B2 (en) 2000-09-07
DK0868529T3 (da) 2004-02-02
NO324963B1 (no) 2008-01-14
EP0868529B1 (de) 2003-10-01

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