ATE319480T1 - Acylierte zyklodextrin guest-inklusion komplexe - Google Patents
Acylierte zyklodextrin guest-inklusion komplexeInfo
- Publication number
- ATE319480T1 ATE319480T1 AT01928906T AT01928906T ATE319480T1 AT E319480 T1 ATE319480 T1 AT E319480T1 AT 01928906 T AT01928906 T AT 01928906T AT 01928906 T AT01928906 T AT 01928906T AT E319480 T1 ATE319480 T1 AT E319480T1
- Authority
- AT
- Austria
- Prior art keywords
- inclusion complex
- acylated cyclodextrin
- molecule
- guest molecule
- inclusion complexes
- Prior art date
Links
- HFHDHCJBZVLPGP-UHFFFAOYSA-N schardinger α-dextrin Chemical class O1C(C(C2O)O)C(CO)OC2OC(C(C2O)O)C(CO)OC2OC(C(C2O)O)C(CO)OC2OC(C(O)C2O)C(CO)OC2OC(C(C2O)O)C(CO)OC2OC2C(O)C(O)C1OC2CO HFHDHCJBZVLPGP-UHFFFAOYSA-N 0.000 title abstract 5
- 239000012736 aqueous medium Substances 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 229920000642 polymer Polymers 0.000 abstract 1
- 230000001376 precipitating effect Effects 0.000 abstract 1
- 239000007787 solid Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
- A61K51/04—Organic compounds
- A61K51/0491—Sugars, nucleosides, nucleotides, oligonucleotides, nucleic acids, e.g. DNA, RNA, nucleic acid aptamers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/69—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit
- A61K47/6949—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit inclusion complexes, e.g. clathrates, cavitates or fullerenes
- A61K47/6951—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit inclusion complexes, e.g. clathrates, cavitates or fullerenes using cyclodextrin
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B82—NANOTECHNOLOGY
- B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
- B82Y5/00—Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Nanotechnology (AREA)
- Biotechnology (AREA)
- Molecular Biology (AREA)
- Physics & Mathematics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Optics & Photonics (AREA)
- Biophysics (AREA)
- General Engineering & Computer Science (AREA)
- Medical Informatics (AREA)
- Crystallography & Structural Chemistry (AREA)
- Biochemistry (AREA)
- Medicinal Preparation (AREA)
- Polysaccharides And Polysaccharide Derivatives (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Compositions Of Macromolecular Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Materials For Medical Uses (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US20350000P | 2000-05-11 | 2000-05-11 | |
| US20571500P | 2000-05-19 | 2000-05-19 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE319480T1 true ATE319480T1 (de) | 2006-03-15 |
Family
ID=26898664
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT01928906T ATE319480T1 (de) | 2000-05-11 | 2001-04-26 | Acylierte zyklodextrin guest-inklusion komplexe |
Country Status (7)
| Country | Link |
|---|---|
| US (2) | US20020025946A1 (de) |
| EP (1) | EP1280559B1 (de) |
| JP (1) | JP2003532757A (de) |
| AT (1) | ATE319480T1 (de) |
| AU (1) | AU2001255709A1 (de) |
| DE (1) | DE60117777T2 (de) |
| WO (1) | WO2001085218A2 (de) |
Families Citing this family (59)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20050113460A1 (en) * | 1999-04-30 | 2005-05-26 | The Regents Of The University Of Michigan | Compositions and methods relating to novel compounds and targets thereof |
| US7144880B2 (en) | 1999-04-30 | 2006-12-05 | Regents Of The University Of Michigan | Compositions relating to novel compounds and targets thereof |
| ATE433752T1 (de) | 1999-04-30 | 2009-07-15 | Univ Michigan | Verwendung von benzodiazepinen zur behandlung von autoimmunischen krankheiten, entzündungen, neoplasien, viralen infektionen und atherosklerosis |
| US20060025388A1 (en) | 1999-04-30 | 2006-02-02 | Glick Gary D | Compositions and methods relating to novel compounds and targets thereof |
| US20040176358A1 (en) * | 1999-04-30 | 2004-09-09 | The Regents Of The University Of Michigan | Compositions and methods relating to novel compounds and targets thereof |
| JP2003321474A (ja) * | 2002-04-30 | 2003-11-11 | Kentetsuku:Kk | 包接化合物 |
| CA2489282A1 (en) * | 2002-06-10 | 2003-12-18 | Leo Rubin | Medical device for intra-lumenal delivery of pharmaceutical agents |
| US7645474B1 (en) * | 2003-07-31 | 2010-01-12 | Advanced Cardiovascular Systems, Inc. | Method and system of purifying polymers for use with implantable medical devices |
| US7785512B1 (en) | 2003-07-31 | 2010-08-31 | Advanced Cardiovascular Systems, Inc. | Method and system of controlled temperature mixing and molding of polymers with active agents for implantable medical devices |
| US20070020196A1 (en) * | 2003-12-31 | 2007-01-25 | Pipkin James D | Inhalant formulation containing sulfoalkyl ether cyclodextrin and corticosteroid prepared from a unit dose suspension |
| US20070020298A1 (en) * | 2003-12-31 | 2007-01-25 | Pipkin James D | Inhalant formulation containing sulfoalkyl ether gamma-cyclodextrin and corticosteroid |
| BRPI0418276B8 (pt) | 2003-12-31 | 2021-05-25 | Cydex Pharmaceuticals Inc | formulação líquida inalável compreeendendo budesonida |
| US20070020299A1 (en) * | 2003-12-31 | 2007-01-25 | Pipkin James D | Inhalant formulation containing sulfoalkyl ether cyclodextrin and corticosteroid |
| ATE446581T1 (de) * | 2004-03-12 | 2009-11-15 | Trinity College Dublin | Magnetoresistives medium |
| US20050208093A1 (en) | 2004-03-22 | 2005-09-22 | Thierry Glauser | Phosphoryl choline coating compositions |
| US20050272723A1 (en) * | 2004-04-27 | 2005-12-08 | The Regents Of The University Of Michigan | Methods and compositions for treating diseases and conditions associated with mitochondrial function |
| US20060052369A1 (en) * | 2004-09-07 | 2006-03-09 | The Regents Of The University Of Michigan | Compositions and methods relating to novel compounds and targets thereof |
| FR2877846B1 (fr) * | 2004-11-15 | 2008-12-05 | Univ Lille Sciences Tech | Biomateriaux porteurs de cyclodextrines aux proprietes d'absorption ameliorees et de liberation progressive et retardee de molecules therapeutiques |
| JP2008528448A (ja) * | 2005-01-03 | 2008-07-31 | ザ リージェンツ オブ ザ ユニバーシティ オブ ミシガン | 新規化合物に関連する組成物および方法、ならびにその標的 |
| WO2007053193A2 (en) | 2005-06-01 | 2007-05-10 | The Regents Of The University Of Michigan | Unsolvated benzodiazepine compositions and methods |
| DE102005033543A1 (de) * | 2005-07-14 | 2007-01-18 | Grünenthal GmbH | Ein einen Duftstoff aufweisendes transdermales therapeutisches System |
| US20070105844A1 (en) * | 2005-10-26 | 2007-05-10 | Regents Of The University Of Michigan | Therapeutic compositions and methods |
| NZ568254A (en) | 2005-11-01 | 2011-06-30 | Univ Michigan | 1,4-Benzodiazepine-2,5-diones for regulating cell death and treating autoimmune diseases |
| WO2007058247A1 (ja) * | 2005-11-17 | 2007-05-24 | Daikin Industries, Ltd. | フルオロポリエーテル分子の包接化合物 |
| US20070249572A1 (en) * | 2005-12-20 | 2007-10-25 | Verus Pharmaceuticals, Inc. | Systems and methods for the delivery of corticosteroids |
| US20070197486A1 (en) * | 2005-12-20 | 2007-08-23 | Verus Pharmaceuticals, Inc. | Methods and systems for the delivery of corticosteroids |
| US20070178050A1 (en) * | 2005-12-20 | 2007-08-02 | Verus Pharmaceuticals, Inc. | Methods and systems for the delivery of corticosteroids having an increased lung depositon |
| US20070185066A1 (en) * | 2005-12-20 | 2007-08-09 | Verus Pharmaceuticals, Inc. | Systems and methods for the delivery of corticosteroids |
| WO2007095341A2 (en) * | 2006-02-15 | 2007-08-23 | Tika Läkemedel Ab | Sterilization of corticosteroids with reduced mass loss |
| US7759338B2 (en) * | 2006-04-27 | 2010-07-20 | The Regents Of The University Of Michigan | Soluble 1,4 benzodiazepine compounds and stable salts thereof |
| KR100718280B1 (ko) * | 2006-06-08 | 2007-05-16 | 재단법인서울대학교산학협력재단 | 사이클로덱스트린 유도체 입자를 도입한 가소제 유출저감형 폴리염화비닐 성형체 및 그 제조방법 |
| EP2418206A3 (de) | 2006-06-09 | 2012-06-27 | The Regents of the University of Michigan | Benzodiazepin-derivate zur behandlung von autoimmunerkrankungen |
| US10149910B2 (en) * | 2007-03-01 | 2018-12-11 | The Procter & Gamble Plaza | Compositions and/or articles comprising cyclodextrin complexing material |
| US11090250B2 (en) | 2007-03-01 | 2021-08-17 | The Procter & Gamble Company | Compositions and/or articles comprising cyclodextrin complexing material |
| CA2680017C (en) | 2007-03-09 | 2013-11-12 | The Regents Of The University Of Michigan | Compositions and methods relating to novel compounds and targets thereof |
| US12370352B2 (en) | 2007-06-28 | 2025-07-29 | Cydex Pharmaceuticals, Inc. | Nasal and ophthalmic delivery of aqueous corticosteroid solutions |
| JP5182661B2 (ja) * | 2007-07-31 | 2013-04-17 | 株式会社ネオス | 固形油及び固形油の製造方法 |
| KR100929920B1 (ko) * | 2007-09-05 | 2009-12-04 | 주식회사 마크로케어 | 사이클로덱스트린 및 이의 유도체에 소수성 생리활성성분이 포접된 포접체의 제조방법 및 이로써 제조된포접체의 용도 |
| AR068374A1 (es) * | 2007-09-06 | 2009-11-11 | Combino Pharm Sl | Nuevas composiciones farmaceuticas del complejo lamivudina beta - ciclodextrina |
| CN101855203B (zh) | 2007-09-14 | 2014-03-19 | 密执安州立大学董事会 | F1f0-atp合成酶抑制剂以及相关的方法 |
| UA99839C2 (ru) | 2007-11-06 | 2012-10-10 | Дзе Риджентс Оф Дзе Юниверсити Оф Мичиган | Бензодиазепиноновые соединения, применяемые при лечении кожных состояний |
| US8054177B2 (en) * | 2007-12-04 | 2011-11-08 | Avaya Inc. | Systems and methods for facilitating a first response mission at an incident scene using patient monitoring |
| EP2352724B1 (de) | 2008-09-11 | 2015-04-22 | The Regents of the University of Michigan | Arylguanidine-f1f0-aptase inhibitoren und deren therapeutischen verwendung |
| US8604023B2 (en) | 2009-04-17 | 2013-12-10 | The Regents Of The University Of Michigan | 1,4-benzodiazepinone compounds and their use in treating cancer |
| WO2011035124A1 (en) | 2009-09-18 | 2011-03-24 | The Regents Of The University Of Michigan | Benzodiazepinone compounds and methods of treatment using same |
| EP2501387B1 (de) | 2009-11-17 | 2016-07-27 | The Regents Of The University Of Michigan | 1,4-benzodiazepin-2,5-dione und verbindungen daraus mit therapeutischen eigenschaften |
| JP5856064B2 (ja) | 2009-11-17 | 2016-02-09 | ザ リージェンツ オブ ザ ユニバーシティ オブ ミシガン | 治療特性を有する１，４−ベンゾジアゼピン−２，５−ジオンおよび関連化合物 |
| CA2816322A1 (en) | 2010-11-01 | 2012-05-10 | Marshall Edwards, Inc. | Isoflavonoid compositions and methods for the treatment of cancer |
| US10328152B2 (en) | 2011-06-16 | 2019-06-25 | Nayan Patel | Method for stabilization and delivery of therapeutic molecules |
| JP5906518B2 (ja) * | 2011-08-11 | 2016-04-20 | 地方独立行政法人鳥取県産業技術センター | シクロデキストリン包接化合物含有組成物の製造方法 |
| CN107427003B (zh) | 2015-02-02 | 2023-01-31 | 梅制药公司 | 联合治疗 |
| WO2018048718A1 (en) | 2016-09-06 | 2018-03-15 | The Procter & Gamble Company | Aerosol compositions |
| BR112019004271B8 (pt) | 2016-09-06 | 2022-09-20 | Procter & Gamble | Composições desodorantes e antitranspirantes |
| EP3765091A4 (de) * | 2018-03-16 | 2022-01-19 | Istanbul Medipol Universitesi | Zur verwendung als histotripsiemittel geeignete einschlusskomplexe |
| JP7323887B2 (ja) * | 2019-02-28 | 2023-08-09 | 国立大学法人北海道大学 | セルロースアセテートフィルム |
| IL292377B2 (en) * | 2019-10-21 | 2023-11-01 | Esolate Ltd | Thin compounds and their production |
| CN114917365B (zh) * | 2022-06-09 | 2023-12-08 | 上海彤颜实业有限公司 | Wgx50环糊精包合物、制备方法、溶解度及环糊精包裹率测定方法 |
| CN114886877B (zh) * | 2022-06-16 | 2024-02-02 | 北京海泰天正医药科技有限公司 | 奥氮平氟西汀复方口溶膜及其制备方法 |
| WO2026085322A1 (en) | 2024-10-18 | 2026-04-23 | Aardvark Therapeutics Inc. | Isoflavonoid formulations and methods of use |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| HU183430B (en) * | 1981-05-12 | 1984-05-28 | Chinoin Gyogyszer Es Vegyeszet | Process for producing cyclodextrine inclusion complexes of n-bracket-1-phenylethyl-bracket closed-3,3-diphenylpropylamine or n-bracket-1-phenylethyl-bracket closed-3,3-diphenylpropylamine-hydrochloride |
| JPS5921613A (ja) * | 1982-07-28 | 1984-02-03 | Takeda Chem Ind Ltd | 直腸投与製剤 |
| US6146358A (en) * | 1989-03-14 | 2000-11-14 | Cordis Corporation | Method and apparatus for delivery of therapeutic agent |
| HU211648A9 (en) * | 1990-03-28 | 1995-12-28 | Chinoin Gyogyszer Es Vegyeszet | Inclusion complexes of 3-morpholino-sydnonimine or its salts or its tautomer isomer, process for the preparation thereof, and pharmaceutical compositions containing the same |
| FR2692168B1 (fr) * | 1992-06-16 | 1995-03-24 | Centre Nat Rech Scient | Préparation et utilisation de nouveaux systèmes colloïdaux dispersibles à base de cyclodextrine, sous forme de nanosphères. |
| US5464650A (en) * | 1993-04-26 | 1995-11-07 | Medtronic, Inc. | Intravascular stent and method |
| DE4414128A1 (de) * | 1994-04-22 | 1995-10-26 | Consortium Elektrochem Ind | Teilweise acylierte beta-Cyclodextrine |
| JPH10194996A (ja) * | 1996-12-25 | 1998-07-28 | Janssen Pharmaceut Nv | アシル化シクロデキストリン含有製薬組成物 |
-
2001
- 2001-04-26 AT AT01928906T patent/ATE319480T1/de not_active IP Right Cessation
- 2001-04-26 WO PCT/US2001/013499 patent/WO2001085218A2/en not_active Ceased
- 2001-04-26 DE DE60117777T patent/DE60117777T2/de not_active Expired - Fee Related
- 2001-04-26 AU AU2001255709A patent/AU2001255709A1/en not_active Abandoned
- 2001-04-26 US US09/843,037 patent/US20020025946A1/en not_active Abandoned
- 2001-04-26 JP JP2001581871A patent/JP2003532757A/ja active Pending
- 2001-04-26 EP EP01928906A patent/EP1280559B1/de not_active Expired - Lifetime
-
2003
- 2003-09-30 US US10/675,900 patent/US20040063663A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| US20020025946A1 (en) | 2002-02-28 |
| DE60117777D1 (de) | 2006-05-04 |
| AU2001255709A1 (en) | 2001-11-20 |
| DE60117777T2 (de) | 2006-08-17 |
| US20040063663A1 (en) | 2004-04-01 |
| WO2001085218A3 (en) | 2002-09-12 |
| EP1280559A2 (de) | 2003-02-05 |
| WO2001085218A2 (en) | 2001-11-15 |
| JP2003532757A (ja) | 2003-11-05 |
| EP1280559B1 (de) | 2006-03-08 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |