ATE319696T1 - Nicht-imidazol aryloxyalkylamine als h3 rezeptor liganden - Google Patents

Nicht-imidazol aryloxyalkylamine als h3 rezeptor liganden

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Publication number
ATE319696T1
ATE319696T1 AT01963813T AT01963813T ATE319696T1 AT E319696 T1 ATE319696 T1 AT E319696T1 AT 01963813 T AT01963813 T AT 01963813T AT 01963813 T AT01963813 T AT 01963813T AT E319696 T1 ATE319696 T1 AT E319696T1
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Austria
Prior art keywords
receptor ligands
aryloxyalkylamines
imidazole
imidazole aryloxyalkylamines
formula
Prior art date
Application number
AT01963813T
Other languages
English (en)
Inventor
Richard Apodaca
Nicholas I Carruthers
Curt A Dvorak
Dale A Rudolph
Chandravadan R Shah
Wei Xiao
Original Assignee
Ortho Mcneil Pharm Inc
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Publication of ATE319696T1 publication Critical patent/ATE319696T1/de

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    • C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D207/32—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C07D207/325—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms with substituted hydrocarbon radicals directly attached to the ring nitrogen atom
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    • C07C217/18—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one etherified hydroxy group and one amino group bound to the carbon skeleton, which is not further substituted the oxygen atom of the etherified hydroxy group being further bound to a carbon atom of a six-membered aromatic ring the six-membered aromatic ring or condensed ring system containing that ring being further substituted
    • C07C217/22—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one etherified hydroxy group and one amino group bound to the carbon skeleton, which is not further substituted the oxygen atom of the etherified hydroxy group being further bound to a carbon atom of a six-membered aromatic ring the six-membered aromatic ring or condensed ring system containing that ring being further substituted by carbon atoms having at least two bonds to oxygen atoms
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US7429586B2 (en) 2008-09-30
WO2002012214A3 (en) 2002-06-20
DE60117814T2 (de) 2006-11-02
BR0113162A (pt) 2004-04-06
DE60117814D1 (de) 2006-05-04
PL360886A1 (en) 2004-09-20
US20100004241A1 (en) 2010-01-07
US7186732B2 (en) 2007-03-06
EP1313721A2 (de) 2003-05-28
ES2260276T3 (es) 2006-11-01
HUP0302959A3 (en) 2006-04-28
AU8473301A (en) 2002-02-18
HK1053110A1 (zh) 2003-10-10
CN1468227A (zh) 2004-01-14
EP1313721B1 (de) 2006-03-08
BRPI0113162B1 (pt) 2016-06-28
HUP0302959A2 (hu) 2003-12-29
KR100819381B1 (ko) 2008-04-04
AU2001284733B2 (en) 2006-11-02
CZ2003685A3 (cs) 2003-08-13
DK1313721T3 (da) 2006-06-26
HU230055B1 (hu) 2015-06-29
US20080306085A1 (en) 2008-12-11
JP2004505960A (ja) 2004-02-26
US20020065278A1 (en) 2002-05-30
KR20030038692A (ko) 2003-05-16
MXPA03001267A (es) 2004-07-30
WO2002012214A2 (en) 2002-02-14
PT1313721E (pt) 2006-06-30
BRPI0113162B8 (pt) 2021-05-25
CA2418369A1 (en) 2002-02-14
US20060235049A1 (en) 2006-10-19

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