ATE319700T1 - Verfahren zu herstellung von tocotrienolen - Google Patents

Verfahren zu herstellung von tocotrienolen

Info

Publication number
ATE319700T1
ATE319700T1 AT01996253T AT01996253T ATE319700T1 AT E319700 T1 ATE319700 T1 AT E319700T1 AT 01996253 T AT01996253 T AT 01996253T AT 01996253 T AT01996253 T AT 01996253T AT E319700 T1 ATE319700 T1 AT E319700T1
Authority
AT
Austria
Prior art keywords
tocotrienols
producing
tocotrienol
antiatherogenic
hypocholesterolemic
Prior art date
Application number
AT01996253T
Other languages
English (en)
Inventor
Lewis Jacobs
Original Assignee
Archer Daniels Midland Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=27359562&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ATE319700(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Archer Daniels Midland Co filed Critical Archer Daniels Midland Co
Application granted granted Critical
Publication of ATE319700T1 publication Critical patent/ATE319700T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/58—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4
    • C07D311/70—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4 with two hydrocarbon radicals attached in position 2 and elements other than carbon and hydrogen in position 6
    • C07D311/72—3,4-Dihydro derivatives having in position 2 at least one methyl radical and in position 6 one oxygen atom, e.g. tocopherols
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyrane Compounds (AREA)
  • Steroid Compounds (AREA)
  • Fats And Perfumes (AREA)
AT01996253T 2000-12-20 2001-12-20 Verfahren zu herstellung von tocotrienolen ATE319700T1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US25648700P 2000-12-20 2000-12-20
US30917101P 2001-08-02 2001-08-02
US10/012,047 US6838104B2 (en) 2000-12-20 2001-12-11 Process for the production of tocotrienols

Publications (1)

Publication Number Publication Date
ATE319700T1 true ATE319700T1 (de) 2006-03-15

Family

ID=27359562

Family Applications (1)

Application Number Title Priority Date Filing Date
AT01996253T ATE319700T1 (de) 2000-12-20 2001-12-20 Verfahren zu herstellung von tocotrienolen

Country Status (7)

Country Link
US (1) US6838104B2 (de)
EP (1) EP1363895B1 (de)
AT (1) ATE319700T1 (de)
AU (1) AU2002227402A1 (de)
DE (1) DE60117869T2 (de)
ES (1) ES2260333T3 (de)
WO (1) WO2002050054A2 (de)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6867308B2 (en) 2001-09-19 2005-03-15 Archer-Daniels-Midland Company Process for separation of tocopherols
US6673945B2 (en) 2001-11-08 2004-01-06 Archer-Daniels Midland Company Process for production of high purity tocopherols
AT414082B (de) * 2002-05-03 2006-09-15 Vis Vitalis Lizenz & Handels Verfahren zur herstellung von tocotrienol-angereicherten präparationen
MY142319A (en) * 2002-08-20 2010-11-15 Malaysian Palm Oil Board Mpob Extraction of palm vitamin e, phytosterols and squalene from palm oil
US7416756B2 (en) 2003-09-10 2008-08-26 Eastman Chemical Company Process for the recovery of a phytolipid composition
EA035619B1 (ru) 2005-06-01 2020-07-16 ПиТиСи ТЕРАПЬЮТИКС, ИНК. Композиции для использования в способе лечения митохондриальных нарушений
EP1986636B1 (de) 2006-02-22 2013-04-24 Edison Pharmaceuticals, Inc. Phenol- und 1,4-benzochinon-derivate zur verwendung in der behandlung von erkrankungen der mitochondrien
KR101481197B1 (ko) * 2007-05-24 2015-01-09 로더스 크로클란 비.브이. 토코페롤 및 토코트리에놀을 함유하는 조성물의 제조방법
EP2344142B1 (de) 2008-09-10 2024-06-26 PTC Therapeutics, Inc. Behandlung von pervasiven entwicklungsstörungen mit redox-aktiven therapeutika
WO2010051277A1 (en) * 2008-10-28 2010-05-06 Edison Pharmaceuticals, Inc. Process for the production of alpha-tocotrienol and derivatives
CA2777479C (en) 2009-04-28 2017-10-17 Ptc Therapeutics, Inc. Treatment of leber's hereditary optic neuropathy and dominant optic atrophy with tocotrienol quinones
JP2012531411A (ja) 2009-06-25 2012-12-10 アンペア ライフ サイエンシーズ，インコーポレイテッド トコトリエノールまたはトコトリエノール濃縮抽出物を用いた広汎性発達障害の処置
MY160111A (en) 2009-07-30 2017-02-28 Chiang Mai Univ System and method for extracting vitamin e from fatty acid distillates
CA2842486C (en) 2011-07-19 2022-09-06 Edison Pharmaceuticals, Inc. Methods for oxidation of alpha tocotrienol in the presence of non-alpha tocotrienols
GB2501519B (en) 2012-04-27 2020-01-15 N V Desmet Ballestra Eng Sa Physical refining of triglyceride oils and fats
JP7117241B2 (ja) 2015-12-16 2022-08-12 ピーティーシー セラピューティクス， インコーポレイテッド 混合されたトコール組成物からアルファ－トコトリエノールを富化するための改良された方法
EP3389646A1 (de) 2015-12-17 2018-10-24 BioElectron Technology Corporation Flouralkyl, flouralkoxy, phenoxy, heteroaryloxy, alkoxy und amin-1,4-benzochinon-derivate zur behandlung von oxidativen stresserkrankungen
DE102020126303A1 (de) 2020-10-07 2022-04-07 B.Braun Avitum Ag Automatisches Entleeren eines Dialysators nach einer Blutbehandlungstherapie
WO2025172861A2 (en) 2024-02-14 2025-08-21 Biosergen As Compositions of a therapeutic polyene macrolide and methods of their use

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4480108A (en) * 1983-08-01 1984-10-30 Eastman Kodak Company Process for separation of tocopherol homologues
US4603142A (en) * 1984-06-01 1986-07-29 Wisconsin Alumni Research Foundation Cholesterol lowering method of use
JPS6193178A (ja) * 1984-10-12 1986-05-12 Agency Of Ind Science & Technol トコトリエノ−ル類の分離方法
US5660692A (en) * 1988-02-24 1997-08-26 Cedars-Sinai Medical Center Method of crosslinking amino acid-containing polymers using photoactivatable chemical crosslinkers
AU618791B2 (en) * 1988-03-16 1992-01-09 Bioindustry Development Centre Production of high concentration tocopherols and tocotrienols from palm oil by-product
EP0543417A1 (de) * 1991-11-22 1993-05-26 Lipogenics, Incorporated Tocotrienole und Focotrienol-ähnliche Verbindungen und Verfahren zu ihrer Verwendung
JPH06193178A (ja) 1992-12-25 1994-07-12 Kurosawa Kensetsu Kk フラットスラブの構築工法
US5487817A (en) * 1993-02-11 1996-01-30 Hoffmann-La Roche Inc. Process for tocopherols and sterols from natural sources
BR9407179A (pt) * 1993-08-06 1996-09-17 Henkel Corp Processos de recuperação tocoferóis a partir de uma mistura gordurosa compreendida de ácidos graxos e tocoferóis de evaporação para a separação de alquil ésteres inferiores de ácido graxo de uma mistura que compreende adicionalmente tocoferóis e esteróis e de separação de um ou mais compostos de tocoferol de um ou mais compostos de esterol
US5512691A (en) * 1994-11-07 1996-04-30 Eastman Chemical Company Process for the production of tocopherol concentrates
US5504220A (en) 1995-08-17 1996-04-02 Eastman Chemical Company Preparation of α-tocopherol
US6177114B1 (en) * 1996-10-31 2001-01-23 Carotina Sdn. Bhd. Refining of edible oil rich in natural carotenes and Vitamin E
MY127634A (en) * 1996-10-31 2006-12-29 Global Palm Products Sdn Bhd Refining of edible oil rich in natural carotenes and vitamin e
US5786491A (en) 1996-12-06 1998-07-28 Eastman Chemical Company Process for crystallizing D-alpha-tocopheryl succinate
EP1051412B1 (de) * 1998-01-29 2003-09-24 Eastman Chemical Company Verfahren zur trennung von einem tocotrienol aus einer tocol enthaltende mischung und deren zusammenstellungen
US6706898B2 (en) 1998-01-29 2004-03-16 Archer-Daniels-Midland Company Methods for separating a tocopherol from a tocopherol-containing mixture
US6197357B1 (en) * 1998-05-28 2001-03-06 University Of Massachusetts Refined vegetable oils and extracts thereof
AU5041400A (en) * 1999-05-24 2000-12-12 America River Nutrition, Inc. Tocotrienols and geranylgeraniol from LTiGTbixa orellanaLT/iGT byproducts

Also Published As

Publication number Publication date
WO2002050054A3 (en) 2003-02-27
AU2002227402A1 (en) 2002-07-01
EP1363895A2 (de) 2003-11-26
DE60117869D1 (de) 2006-05-04
EP1363895B1 (de) 2006-03-08
ES2260333T3 (es) 2006-11-01
US6838104B2 (en) 2005-01-04
WO2002050054A2 (en) 2002-06-27
DE60117869T2 (de) 2006-07-27
US20020142083A1 (en) 2002-10-03

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Legal Events

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