ATE320000T1 - Ein biolumineszenz resonanz energie transfer (bret) system mit breitem spektralen resolution zwischen donator- und akzeptor-emission wellenlänge und ihre anwendung - Google Patents

Ein biolumineszenz resonanz energie transfer (bret) system mit breitem spektralen resolution zwischen donator- und akzeptor-emission wellenlänge und ihre anwendung

Info

Publication number
ATE320000T1
ATE320000T1 AT00986922T AT00986922T ATE320000T1 AT E320000 T1 ATE320000 T1 AT E320000T1 AT 00986922 T AT00986922 T AT 00986922T AT 00986922 T AT00986922 T AT 00986922T AT E320000 T1 ATE320000 T1 AT E320000T1
Authority
AT
Austria
Prior art keywords
bret
spectral resolution
energy transfer
emission wavelength
resonance energy
Prior art date
Application number
AT00986922T
Other languages
English (en)
Inventor
Erik Joly
Original Assignee
Perkinelmer Biosignal Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Perkinelmer Biosignal Inc filed Critical Perkinelmer Biosignal Inc
Application granted granted Critical
Publication of ATE320000T1 publication Critical patent/ATE320000T1/de

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/536—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase
    • G01N33/542—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase with steric inhibition or signal modification, e.g. fluorescent quenching
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/531—Production of immunochemical test materials
    • G01N33/532—Production of labelled immunochemicals
    • G01N33/533—Production of labelled immunochemicals with fluorescent label
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/43504—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans from invertebrates
    • G01N2333/43595—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans from invertebrates from coelenteratae, e.g. medusae

Landscapes

  • Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Food Science & Technology (AREA)
  • Biochemistry (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Luminescent Compositions (AREA)
  • Physical Or Chemical Processes And Apparatus (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
AT00986922T 1999-12-22 2000-12-22 Ein biolumineszenz resonanz energie transfer (bret) system mit breitem spektralen resolution zwischen donator- und akzeptor-emission wellenlänge und ihre anwendung ATE320000T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CA2291968 1999-12-22
CA2314861 2000-08-02

Publications (1)

Publication Number Publication Date
ATE320000T1 true ATE320000T1 (de) 2006-03-15

Family

ID=25681386

Family Applications (1)

Application Number Title Priority Date Filing Date
AT00986922T ATE320000T1 (de) 1999-12-22 2000-12-22 Ein biolumineszenz resonanz energie transfer (bret) system mit breitem spektralen resolution zwischen donator- und akzeptor-emission wellenlänge und ihre anwendung

Country Status (6)

Country Link
US (1) US20030203404A1 (de)
EP (1) EP1295121B1 (de)
AT (1) ATE320000T1 (de)
AU (1) AU2334801A (de)
DE (1) DE60026603T2 (de)
WO (1) WO2001046691A1 (de)

Families Citing this family (33)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2826666B1 (fr) * 2001-07-02 2004-07-02 Novaleads Procede de selection d'agents bio-actifs par couplage de luminescence et systeme cellulaire vivant pour la mise en oeuvre de ce procede
CA2484209C (en) * 2002-05-03 2013-06-11 Exelixis, Inc. Protein kinase modulators and methods of use
EP1546201A4 (de) * 2002-09-11 2006-08-16 Merck & Co Inc Nukleinsäuresequenzen, die für neue punktmutationen auf mglur2 und mglur3 codieren
AU2003300424A1 (en) * 2002-10-11 2004-05-04 7Tm Pharma A/S Method for enhancing and prolonging the bioluminescence resonance energy transfer (bret) signal in a bret assay and a substrate solution for use in a bret assay
ATE419274T1 (de) 2002-10-25 2009-01-15 Mds Analytical Technologies Us Verfahren zur identifizierung von transmembranrezeptoragonisten mit reduzierter internalisierung
DE10318048A1 (de) * 2003-04-17 2004-11-04 Axaron Bioscience Ag Nicht fluoreszierende, durch Proteolyse zur Fluoreszenz aktivierbare Reporterproteine und ihre Verwendung zur Detektion Protease-abhängiger Ereignisse
US20090088337A1 (en) * 2003-07-10 2009-04-02 Ronald Gill RET-Based Analyte Detection
EP1888788B1 (de) * 2005-06-03 2011-09-14 Beacon Biotechnology LLC Chemilumineszenz-nukleinsäuretest
WO2007139080A1 (ja) * 2006-05-26 2007-12-06 Noacell Science Co., Ltd. 受容体及びイオンチャンネルを介したカルシウムの応答と引き続いて起こる遺伝子発現を測定する連続アッセイ法
US8530178B2 (en) 2006-10-17 2013-09-10 Zymera, Inc. Hydrolase detection system with caged substrates
US9091659B2 (en) 2006-10-17 2015-07-28 Zymera, Inc. Hydrolase detection system with sterically caged substrates
EP2084536A4 (de) * 2006-10-18 2010-03-17 Blind Pig Proteomics Incs Analytnachweis auf ret-basis
WO2008055313A1 (en) 2006-11-10 2008-05-15 Dimerix Bioscience Pty Ltd Detection system and uses therefor
WO2008109463A2 (en) * 2007-03-02 2008-09-12 University Of Massachusetts Red-shifted luciferase
WO2008109459A1 (en) 2007-03-02 2008-09-12 University Of Massachusetts Luciferins
JP2008222084A (ja) * 2007-03-14 2008-09-25 Yamaha Motor Electronics Co Ltd 電動ゴルフカーのブレーキ劣化検出方法及びこれを用いた電動ゴルフカー
US8263585B2 (en) 2007-05-04 2012-09-11 Novartis Ag Organic compounds
JP5224100B2 (ja) * 2008-03-05 2013-07-03 独立行政法人産業技術総合研究所 変異型ルシフェラーゼ
US8268834B2 (en) 2008-03-19 2012-09-18 Novartis Ag Pyrazine derivatives that inhibit phosphatidylinositol 3-kinase enzyme
SG172321A1 (en) 2009-01-29 2011-07-28 Commw Scient Ind Res Org Measuring g protein coupled receptor activation
US8546568B2 (en) 2009-02-09 2013-10-01 Jnc Corporation Coelenterazine analogs and manufacturing method thereof
US20110097723A1 (en) * 2009-09-19 2011-04-28 Qun Liu Methods and reagents for analyte detection
FR2958293B1 (fr) 2010-04-01 2014-09-26 Centre Nat Rech Scient Outils pour l'identification de ligands de lingo-1,lingo-2, lingo-3 et lingo-4, et utilisations
AU2013204332B2 (en) 2012-04-16 2015-07-16 Commonwealth Scientific And Industrial Research Organisation Methods and systems for detecting an analyte or classifying a sample
US10067149B2 (en) 2012-12-12 2018-09-04 Promega Corporation Recognition of cellular target binding by a bioactive agent using intracellular bioluminescence resonance energy transfer
DK2932267T3 (da) 2012-12-12 2020-07-20 Promega Corp Genkendelse af binding af cellulært mål ved hjælp af et bioaktivt stof under anvendelse af intracellulær bioluminescensresonans-energioverførsel
DE102013113348B4 (de) * 2013-12-02 2017-04-13 Karlheinz Mayer Vorrichtung zum Messen von DNA-Quantenzuständen sowie Verwendung derselben
CN104021393A (zh) * 2014-03-31 2014-09-03 河海大学 基于萤火虫优化的高光谱遥感影像波段选择方法
EP3056902B1 (de) * 2015-02-16 2020-04-01 Universite De Bordeaux Neuartige spannungsabhängige Ionenkanalfusionen und Verwendungsverfahren dafür
AU2017358067B2 (en) 2016-11-14 2024-04-18 PPB Technology Pty Ltd Protease sensor molecules
CA3071994A1 (en) 2017-08-08 2019-02-14 Commonwealth Scientific And Industrial Research Organisation Carbohydrate sensors
EP3882632A1 (de) 2020-03-18 2021-09-22 Universite De Bordeaux Neuartige ionenleitende kanalfusionuntereinheiten und verfahren zur verwendung davon
CN115994578B (zh) * 2022-11-23 2024-01-26 广东工业大学 一种基于萤火虫算法的关联方法及系统

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5976796A (en) * 1996-10-04 1999-11-02 Loma Linda University Construction and expression of renilla luciferase and green fluorescent protein fusion genes

Also Published As

Publication number Publication date
WO2001046691A1 (en) 2001-06-28
DE60026603T2 (de) 2007-03-01
DE60026603D1 (de) 2006-05-04
US20030203404A1 (en) 2003-10-30
AU2334801A (en) 2001-07-03
EP1295121A1 (de) 2003-03-26
EP1295121B1 (de) 2006-03-08

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