ATE320265T1 - Staphylococcus-antigene und impstoff - Google Patents
Staphylococcus-antigene und impstoffInfo
- Publication number
- ATE320265T1 ATE320265T1 AT00916405T AT00916405T ATE320265T1 AT E320265 T1 ATE320265 T1 AT E320265T1 AT 00916405 T AT00916405 T AT 00916405T AT 00916405 T AT00916405 T AT 00916405T AT E320265 T1 ATE320265 T1 AT E320265T1
- Authority
- AT
- Austria
- Prior art keywords
- antigen
- staphylococcus
- strains
- carry
- vaccine
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
- C07K16/12—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from bacteria
- C07K16/1267—Gram-positive bacteria
- C07K16/1271—Micrococcaceae (F); Staphylococcaceae (F), e.g. Staphylococcus (G)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/02—Bacterial antigens
- A61K39/085—Staphylococcus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- C07K14/305—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Micrococcaceae (F)
- C07K14/31—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Micrococcaceae (F) from Staphylococcus (G)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/60—Medicinal preparations containing antigens or antibodies characteristics by the carrier linked to the antigen
- A61K2039/6031—Proteins
- A61K2039/6037—Bacterial toxins, e.g. diphteria toxoid [DT], tetanus toxoid [TT]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/60—Medicinal preparations containing antigens or antibodies characteristics by the carrier linked to the antigen
- A61K2039/6031—Proteins
- A61K2039/6068—Other bacterial proteins, e.g. OMP
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/975—Kit
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
- Y10S530/866—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof involving immunoglobulin or antibody fragment, e.g. fab', fab, fv, fc, heavy chain or light chain
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Immunology (AREA)
- Biochemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biophysics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Gastroenterology & Hepatology (AREA)
- Engineering & Computer Science (AREA)
- Physical Education & Sports Medicine (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Epidemiology (AREA)
- Oncology (AREA)
- Rheumatology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Communicable Diseases (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicinal Preparation (AREA)
- Materials For Medical Uses (AREA)
- Cosmetics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US09/272,359 US6936258B1 (en) | 1999-03-19 | 1999-03-19 | Staphylococcus antigen and vaccine |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE320265T1 true ATE320265T1 (de) | 2006-04-15 |
Family
ID=23039462
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT00916405T ATE320265T1 (de) | 1999-03-19 | 2000-03-17 | Staphylococcus-antigene und impstoff |
Country Status (15)
| Country | Link |
|---|---|
| US (2) | US6936258B1 (de) |
| EP (1) | EP1162997B1 (de) |
| JP (1) | JP4656728B2 (de) |
| AT (1) | ATE320265T1 (de) |
| AU (1) | AU773226B2 (de) |
| BR (1) | BR0009157B1 (de) |
| CA (1) | CA2366433C (de) |
| CY (1) | CY1105500T1 (de) |
| DE (1) | DE60026691T2 (de) |
| DK (1) | DK1162997T3 (de) |
| ES (1) | ES2261192T3 (de) |
| MX (1) | MXPA01009476A (de) |
| NZ (1) | NZ514455A (de) |
| PT (1) | PT1162997E (de) |
| WO (1) | WO2000056357A2 (de) |
Families Citing this family (63)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6294177B1 (en) * | 1996-09-11 | 2001-09-25 | Nabi | Staphylococcus aureus antigen-containing whole cell vaccine |
| US6936258B1 (en) * | 1999-03-19 | 2005-08-30 | Nabi Biopharmaceuticals | Staphylococcus antigen and vaccine |
| AT410798B (de) * | 2001-01-26 | 2003-07-25 | Cistem Biotechnologies Gmbh | Verfahren zur identifizierung, isolierung und herstellung von antigenen gegen ein spezifisches pathogen |
| EP1470237A4 (de) * | 2001-12-21 | 2006-02-01 | Biosynexus Inc | Gegen peptidoglycan grampositiver bakterien gerichtete multifunktionelle monoklonale antikörper |
| US20060134141A1 (en) * | 2004-12-14 | 2006-06-22 | Nabi Biopharmaceuticals | Glycoconjugate vaccines containing peptidoglycan |
| KR20070104590A (ko) * | 2005-01-10 | 2007-10-26 | 나비 바이오파마슈티컬즈 | 스타필로코쿠스 아우레우스 감염을 치료하는 방법 |
| CN102698261A (zh) | 2005-06-13 | 2012-10-03 | 葛兰素史密斯克蓝生物品公司 | Panton-valentine杀白细胞素用于治疗和预防葡萄球菌感染的用途 |
| WO2007008904A2 (en) | 2005-07-08 | 2007-01-18 | The Government Of The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services | Targeting poly-gamma-glutamic acid to treat staphylococcus epidermidis and related infections |
| AU2007281934B2 (en) | 2006-01-18 | 2012-11-15 | University Of Chicago | Compositions and methods related to Staphylococcal bacterium proteins |
| EP1998802A2 (de) | 2006-03-30 | 2008-12-10 | GlaxoSmithKline Biologicals S.A. | Immunogene zusammensetzung |
| EP2719397A1 (de) | 2006-06-12 | 2014-04-16 | GlaxoSmithKline Biologicals SA | Verwendung von Alpha-Toxin zur Behandlung und Prävention von Staphylococcus-Infektionen |
| AU2008292897B2 (en) | 2007-08-31 | 2015-01-22 | University Of Chicago | Methods and compositions related to immunizing against staphylococcal lung diseases and conditions |
| WO2010042481A1 (en) | 2008-10-06 | 2010-04-15 | University Of Chicago | Compositions and methods related to bacterial eap, emp, and/or adsa proteins |
| US8101190B2 (en) * | 2009-03-03 | 2012-01-24 | Ingen Biosciences | Method for diagnosing staphylococcal infections |
| PT3281947T (pt) | 2009-04-03 | 2020-05-07 | Univ Chicago | Composições e métodos relacionados com variantes da proteína a (spa) |
| BRPI1015567A2 (pt) | 2009-06-22 | 2021-08-31 | Wyeth Llc | Composições imunogênicas de antígenos de staphylococcus aureus |
| TWI505834B (zh) | 2009-06-22 | 2015-11-01 | Wyeth Llc | 組合物及製備金黃色葡萄球菌血清型5及8莢膜多醣結合物之免疫原性組合物之方法 |
| GB0913680D0 (en) | 2009-08-05 | 2009-09-16 | Glaxosmithkline Biolog Sa | Immunogenic composition |
| GB0913681D0 (en) | 2009-08-05 | 2009-09-16 | Glaxosmithkline Biolog Sa | Immunogenic composition |
| US10266585B2 (en) | 2009-08-28 | 2019-04-23 | The Board Of Regents Of The Univerity Of Texas System | Methods of treating brain injury |
| ES2812523T3 (es) | 2009-09-30 | 2021-03-17 | Glaxosmithkline Biologicals Sa | Conjugación de polisacáridos capsulares de Staphylococcus aureus de tipo 5 y de tipo 8 |
| MX345967B (es) | 2009-10-30 | 2017-02-28 | Novartis Ag | Purificacion de sacaridos capsulares de staphylococcus aureus tipo 5 y tipo 8. |
| EP2555794A4 (de) | 2010-04-05 | 2014-01-15 | Univ Chicago | Zusammensetzungen und verfahren im zusammenhang mit protein-a-(spa)-antikörpern als immunreaktionsverstärker |
| EP2588120B1 (de) | 2010-07-02 | 2017-11-15 | The University of Chicago | Zusammensetzungen und verfahren bezüglich protein-a (spa)-varianten |
| EP2614074A1 (de) | 2010-09-09 | 2013-07-17 | The University of Chicago | Verfahren und zusammensetzungen mit schützenden staphylokokken-antigenen |
| WO2012051498A2 (en) | 2010-10-15 | 2012-04-19 | The Board Of Regents Of The University Of Texas System | Antibodies that bind amyloid oligomers |
| RU2570730C2 (ru) | 2010-12-22 | 2015-12-10 | УАЙТ ЭлЭлСи | Стабильные иммуногенные композиции антигенов staphylococcus aureus |
| US8945588B2 (en) | 2011-05-06 | 2015-02-03 | The University Of Chicago | Methods and compositions involving protective staphylococcal antigens, such as EBH polypeptides |
| EP2729178A1 (de) | 2011-07-08 | 2014-05-14 | Novartis AG | Tyrosinverbindungsverfahren |
| EP2744517B1 (de) | 2011-08-15 | 2019-03-13 | The University of Chicago | Zusammensetzungen und verfahren in zusammenhang mit antikörpern gegen das staphylokokken-protein a |
| US9493517B2 (en) | 2011-11-07 | 2016-11-15 | Glaxosmithkline Biologicals Sa | Conjugates comprising an antigen and a carrier molecule |
| US9115066B2 (en) | 2011-12-14 | 2015-08-25 | Indicator Systems International, Inc. | Trisubstituted methyl alcohols and their polymerizable derivatives |
| HRP20201127T1 (hr) | 2012-04-26 | 2020-11-27 | University Of Chicago | Antigeni stafilokokne koagulaze i metode primjene istih |
| HK1207321A1 (en) | 2012-04-26 | 2016-01-29 | University Of Chicago | Compositions and methods related to antibodies that neutralize coagulase activity during staphylococcus aureus disease |
| HUE049531T2 (hu) | 2012-08-16 | 2020-10-28 | Pfizer | Glikokonjugációs eljárások és kompozíciók |
| KR101980989B1 (ko) | 2012-12-20 | 2019-05-21 | 화이자 인코포레이티드 | 당접합 방법 |
| US10125373B2 (en) | 2013-01-22 | 2018-11-13 | Arizona Board Of Regents On Behalf Of Arizona State University | Geminiviral vector for expression of rituximab |
| GB201310008D0 (en) | 2013-06-05 | 2013-07-17 | Glaxosmithkline Biolog Sa | Immunogenic composition for use in therapy |
| KR20160040556A (ko) | 2013-07-11 | 2016-04-14 | 노파르티스 아게 | 미생물 트랜스글루타미나제를 사용한 리신-특이적 화학효소적 단백질 변형 |
| US11160855B2 (en) | 2014-01-21 | 2021-11-02 | Pfizer Inc. | Immunogenic compositions comprising conjugated capsular saccharide antigens and uses thereof |
| JP6612260B2 (ja) | 2014-01-21 | 2019-11-27 | ファイザー・インク | 肺炎連鎖球菌(Streptococcus pneumoniae)莢膜多糖およびそのコンジュゲート |
| CA3206112A1 (en) | 2014-01-21 | 2015-07-30 | Pfizer Inc. | Immunogenic compositions comprising conjugated capsular saccharide antigens and uses thereof |
| MX371453B (es) | 2014-01-21 | 2020-01-29 | Pfizer | Polisacaridos capsulares de streptococcus pneumoniae y conjugados de los mismos. |
| ES2930318T3 (es) | 2014-02-14 | 2022-12-09 | Pfizer | Conjugados glucoproteicos inmunogénicos |
| EP3229833A1 (de) | 2014-12-10 | 2017-10-18 | GlaxoSmithKline Biologicals SA | Behandlungsverfahren |
| PL3244917T3 (pl) | 2015-01-15 | 2023-07-17 | Pfizer Inc. | Kompozycje immunogenne do zastosowania w szczepionkach przeciwko pneumokokom |
| IL255106B2 (en) | 2015-05-04 | 2023-04-01 | Pfizer | Protein-polysaccharide conjugates of group b streptococcus, methods for preparing conjugates, immunogenic preparations containing conjugates and their uses |
| EP3325008B1 (de) | 2015-07-21 | 2025-09-10 | Pfizer Inc. | Immunogene zusammensetzungen mit konjugierten kapselsaccharid-antigenen, kits damit und verwendungen davon |
| WO2017085586A1 (en) | 2015-11-20 | 2017-05-26 | Pfizer Inc. | Immunogenic compositions for use in pneumococcal vaccines |
| US11246924B2 (en) | 2016-04-01 | 2022-02-15 | Duke University | Alpha-helical peptide nanofibers as a self-adjuvanting vaccine platform |
| US10751402B2 (en) | 2016-11-09 | 2020-08-25 | Pfizer Inc. | Immunogenic compositions and uses thereof |
| US11413344B2 (en) | 2017-01-20 | 2022-08-16 | Pfizer Inc. | Immunogenic compositions for use in pneumococcal vaccines |
| US11413336B2 (en) | 2018-03-23 | 2022-08-16 | Board Of Regents, The University Of Texas System | Coccidioides antigens and methods of their use |
| CA3120922A1 (en) | 2018-12-12 | 2020-06-18 | Pfizer Inc. | Immunogenic multiple hetero-antigen polysaccharide-protein conjugates and uses thereof |
| US20220184199A1 (en) | 2019-04-10 | 2022-06-16 | Pfizer Inc. | Immunogenic compositions comprising conjugated capsular saccharide antigens, kits comprising the same and uses thereof |
| BR112021022902A2 (pt) | 2019-05-14 | 2022-01-25 | Univ Chicago | Métodos e composições que compreendem variantes de proteína a staphylococcus (spa) |
| EP4203995A1 (de) | 2020-08-26 | 2023-07-05 | Pfizer Inc. | Gruppe-b-streptococcus-polysaccharid-protein-konjugate, verfahren zur herstellung von konjugaten, immunogene zusammensetzungen mit konjugaten und verwendungen davon |
| AU2021373358B2 (en) | 2020-11-04 | 2026-01-08 | Pfizer Inc. | Immunogenic compositions for use in pneumococcal vaccines |
| CA3218544A1 (en) | 2021-05-03 | 2022-11-10 | Pfizer Inc. | Vaccination against bacterial and betacoronavirus infections |
| WO2022234416A1 (en) | 2021-05-03 | 2022-11-10 | Pfizer Inc. | Vaccination against pneumoccocal and covid-19 infections |
| WO2024084397A1 (en) | 2022-10-19 | 2024-04-25 | Pfizer Inc. | Vaccination against pneumoccocal and covid-19 infections |
| EP4713008A2 (de) | 2023-05-19 | 2026-03-25 | GlaxoSmithKline Biologicals S.A. | Verfahren zur auslösung einer immunreaktion auf das respiratorische synzykialvirus und streptococcus pneumoniae-infektion |
| WO2026038177A1 (en) | 2024-08-16 | 2026-02-19 | Pfizer Inc. | Immunogenic compositions and uses thereof |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2619122B1 (fr) | 1987-08-03 | 1990-03-09 | Pasteur Institut | Procede d'obtention de polyosides capsulaires de staphylocoques, polyosides obtenus, applications de ces polyosides et souches pour la mise en oeuvre du procede |
| US7279162B1 (en) * | 1990-10-22 | 2007-10-09 | Henry M. Jackson Foundation For The Advancement Of Military Medicine | Isolated broadly reactive opsonic immunoglobulin for treating a pathogenic coagulase-negative staphylococcus infection |
| FR2682388B1 (fr) * | 1991-10-10 | 1995-06-09 | Pasteur Merieux Serums Vacc | Procede de preparation d'un oligoside par depolymerisation d'un polyoside issu d'un agent pathogene, oligoside ainsi obtenu et son utilisation notamment comme agent vaccinal. |
| AU681573B2 (en) * | 1991-11-22 | 1997-09-04 | Glaxosmithkline Biologicals Sa | Type I and type II surface antigens associated with (staphylococcus epidermidis) |
| US5770208A (en) * | 1996-09-11 | 1998-06-23 | Nabi | Staphylococcus aureus B-linked hexosamine antigen |
| US6294177B1 (en) * | 1996-09-11 | 2001-09-25 | Nabi | Staphylococcus aureus antigen-containing whole cell vaccine |
| WO1998028002A1 (en) | 1996-12-20 | 1998-07-02 | Research Foundation Of The City University Of New York | A novel pathogenic coccoid organism, staphylococcus leei, with trophism for gastric mucin |
| US5965374A (en) * | 1997-10-16 | 1999-10-12 | Biowhittaker Technologies, Inc. | Glucan-specific assay |
| CA2344166C (en) * | 1998-09-14 | 2008-11-18 | Nabi | Compositions of .beta.-glucans and specific igiv |
| US7030101B2 (en) * | 1998-09-14 | 2006-04-18 | Nabi Biopharmaceuticals | Compositions of β-glucans and specific antibodies |
| US6936258B1 (en) * | 1999-03-19 | 2005-08-30 | Nabi Biopharmaceuticals | Staphylococcus antigen and vaccine |
| US20030113350A1 (en) * | 2001-09-19 | 2003-06-19 | Fattom Ali I. | Glycoconjugate vaccines for use in immune-compromised populations |
-
1999
- 1999-03-19 US US09/272,359 patent/US6936258B1/en not_active Expired - Fee Related
-
2000
- 2000-03-17 NZ NZ514455A patent/NZ514455A/en not_active IP Right Cessation
- 2000-03-17 MX MXPA01009476A patent/MXPA01009476A/es active IP Right Grant
- 2000-03-17 EP EP00916405A patent/EP1162997B1/de not_active Expired - Lifetime
- 2000-03-17 DE DE60026691T patent/DE60026691T2/de not_active Expired - Lifetime
- 2000-03-17 WO PCT/US2000/006922 patent/WO2000056357A2/en not_active Ceased
- 2000-03-17 PT PT00916405T patent/PT1162997E/pt unknown
- 2000-03-17 AU AU37513/00A patent/AU773226B2/en not_active Ceased
- 2000-03-17 BR BRPI0009157-0B1A patent/BR0009157B1/pt not_active IP Right Cessation
- 2000-03-17 JP JP2000606261A patent/JP4656728B2/ja not_active Expired - Fee Related
- 2000-03-17 CA CA2366433A patent/CA2366433C/en not_active Expired - Fee Related
- 2000-03-17 DK DK00916405T patent/DK1162997T3/da active
- 2000-03-17 ES ES00916405T patent/ES2261192T3/es not_active Expired - Lifetime
- 2000-03-17 AT AT00916405T patent/ATE320265T1/de active
-
2004
- 2004-12-20 US US11/014,997 patent/US7531633B2/en not_active Expired - Fee Related
-
2006
- 2006-05-12 CY CY20061100620T patent/CY1105500T1/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| CA2366433C (en) | 2012-01-03 |
| AU773226B2 (en) | 2004-05-20 |
| EP1162997B1 (de) | 2006-03-15 |
| US7531633B2 (en) | 2009-05-12 |
| DK1162997T3 (da) | 2006-07-17 |
| BR0009157B1 (pt) | 2013-12-24 |
| BR0009157A (pt) | 2002-04-16 |
| AU3751300A (en) | 2000-10-09 |
| JP4656728B2 (ja) | 2011-03-23 |
| MXPA01009476A (es) | 2003-08-19 |
| DE60026691T2 (de) | 2006-09-07 |
| DE60026691D1 (de) | 2006-05-11 |
| US6936258B1 (en) | 2005-08-30 |
| NZ514455A (en) | 2003-11-28 |
| PT1162997E (pt) | 2006-07-31 |
| US20050118190A1 (en) | 2005-06-02 |
| CY1105500T1 (el) | 2010-04-28 |
| WO2000056357A2 (en) | 2000-09-28 |
| EP1162997A2 (de) | 2001-12-19 |
| JP2002539272A (ja) | 2002-11-19 |
| ES2261192T3 (es) | 2006-11-16 |
| WO2000056357A3 (en) | 2001-02-01 |
| CA2366433A1 (en) | 2000-09-28 |
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