ATE321050T1 - (1,4)diazocino(7,8,1-hi)indolderivate als antipsychotische mittel und mittel gegen obesität - Google Patents

(1,4)diazocino(7,8,1-hi)indolderivate als antipsychotische mittel und mittel gegen obesität

Info

Publication number: ATE321050T1
Authority: AT; Austria
Prior art keywords: diazocino; antipsychotic; indole derivatives; obesity agents; obesity
Prior art date: 2002-04-25

Application number

AT03741766T

Other languages

English (en)

Inventor

Hong Gao

Gary Paul Stack

Annmarie Louise Sabb

Original Assignee

Wyeth Corp

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2002-04-25

Filing date

2003-04-23

Publication date

2006-04-15

2003-04-23 Application filed by Wyeth Corp filed Critical Wyeth Corp

2006-04-15 Application granted granted Critical

2006-04-15 Publication of ATE321050T1 publication Critical patent/ATE321050T1/de

Links

SIKJAQJRHWYJAI-UHFFFAOYSA-N Indole Chemical class C1=CC=C2NC=CC2=C1 SIKJAQJRHWYJAI-UHFFFAOYSA-N 0.000 title 1
239000000883 anti-obesity agent Substances 0.000 title 1
230000000561 anti-psychotic effect Effects 0.000 title 1
229940125710 antiobesity agent Drugs 0.000 title 1
239000000164 antipsychotic agent Substances 0.000 title 1
229940054051 antipsychotic indole derivative Drugs 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/06—Peri-condensed systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/10—Drugs for genital or sexual disorders; Contraceptives for impotence
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/06—Antigout agents, e.g. antihyperuricemic or uricosuric agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61P25/06—Antimigraine agents
- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61P25/08—Antiepileptics; Anticonvulsants
- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
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- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61P25/00—Drugs for disorders of the nervous system
- A61P25/26—Psychostimulants, e.g. nicotine, cocaine
- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
- A—HUMAN NECESSITIES
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- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Veterinary Medicine (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Public Health (AREA)
Neurology (AREA)
Biomedical Technology (AREA)
Neurosurgery (AREA)
Diabetes (AREA)
Psychiatry (AREA)
Pain & Pain Management (AREA)
Reproductive Health (AREA)
Endocrinology (AREA)
Obesity (AREA)
Hematology (AREA)
Heart & Thoracic Surgery (AREA)
Rheumatology (AREA)
Cardiology (AREA)
Gynecology & Obstetrics (AREA)
Physical Education & Sports Medicine (AREA)
Anesthesiology (AREA)
Child & Adolescent Psychology (AREA)
Gastroenterology & Hepatology (AREA)
Immunology (AREA)
Orthopedic Medicine & Surgery (AREA)
Addiction (AREA)
Psychology (AREA)
Hospice & Palliative Care (AREA)
Emergency Medicine (AREA)
Nutrition Science (AREA)

AT03741766T 2002-04-25 2003-04-23 (1,4)diazocino(7,8,1-hi)indolderivate als antipsychotische mittel und mittel gegen obesität ATE321050T1 (de)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US37534902P	2002-04-25	2002-04-25

Publications (1)

Publication Number	Publication Date
ATE321050T1 true ATE321050T1 (de)	2006-04-15

Family

ID=29270634

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT03741766T ATE321050T1 (de)	2002-04-25	2003-04-23	(1,4)diazocino(7,8,1-hi)indolderivate als antipsychotische mittel und mittel gegen obesität

Country Status (15)

Country	Link
US (1)	US7012089B2 (de)
EP (1)	EP1497296B1 (de)
JP (1)	JP4537076B2 (de)
CN (2)	CN100376581C (de)
AR (1)	AR039668A1 (de)
AT (1)	ATE321050T1 (de)
AU (1)	AU2003263119B2 (de)
BR (1)	BR0309499A (de)
CA (1)	CA2481324A1 (de)
DE (1)	DE60304188T8 (de)
DK (1)	DK1497296T3 (de)
ES (1)	ES2260631T3 (de)
MX (1)	MXPA04010373A (de)
TW (1)	TW200307540A (de)
WO (1)	WO2003091257A1 (de)

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ES2329553T4 (es)	2000-12-20	2010-12-07	Bristol-Myers Squibb Company	Pirroloquinolinas y piridoquinolinas sustituidas como agonistas y antagonistas de serotonina.
EP1414826A1 (de)	2001-08-06	2004-05-06	PHARMACIA & UPJOHN COMPANY	Therapeutisch verwendbare tetracyclische 5-ht-liganden
TWI312781B (en)	2002-04-25	2009-08-01		[1,4]diazepino[6,7,1-ij]quinoline derivatives as antipsychotic and antiobesity agents
TW200307682A (en)	2002-04-25	2003-12-16	Wyeth Corp	1,2,3,4,7,8-Hexahydro-6H-[1,4]diazepino[6,7,1-ij]quinoline derivatives as antipsychotic and antiobesity agents

2003
- 2003-04-22 TW TW092109350A patent/TW200307540A/zh unknown
- 2003-04-23 BR BR0309499-5A patent/BR0309499A/pt not_active IP Right Cessation
- 2003-04-23 ES ES03741766T patent/ES2260631T3/es not_active Expired - Lifetime
- 2003-04-23 JP JP2003587815A patent/JP4537076B2/ja not_active Expired - Fee Related
- 2003-04-23 EP EP03741766A patent/EP1497296B1/de not_active Expired - Lifetime
- 2003-04-23 CN CNB038143496A patent/CN100376581C/zh not_active Expired - Fee Related
- 2003-04-23 AT AT03741766T patent/ATE321050T1/de not_active IP Right Cessation
- 2003-04-23 DK DK03741766T patent/DK1497296T3/da active
- 2003-04-23 WO PCT/US2003/012691 patent/WO2003091257A1/en not_active Ceased
- 2003-04-23 CA CA002481324A patent/CA2481324A1/en not_active Abandoned
- 2003-04-23 AU AU2003263119A patent/AU2003263119B2/en not_active Ceased
- 2003-04-23 DE DE60304188T patent/DE60304188T8/de active Active
- 2003-04-23 MX MXPA04010373A patent/MXPA04010373A/es active IP Right Grant
- 2003-04-23 CN CNA2006101464687A patent/CN101003538A/zh not_active Withdrawn
- 2003-04-24 AR ARP030101429A patent/AR039668A1/es unknown
- 2003-04-24 US US10/422,657 patent/US7012089B2/en not_active Expired - Fee Related

Also Published As

Publication number	Publication date
DK1497296T3 (da)	2006-06-06
DE60304188T2 (de)	2006-12-28
DE60304188T8 (de)	2007-04-19
AU2003263119A1 (en)	2003-11-10
EP1497296B1 (de)	2006-03-22
WO2003091257A1 (en)	2003-11-06
MXPA04010373A (es)	2005-02-03
DE60304188D1 (de)	2006-05-11
BR0309499A (pt)	2005-02-15
CN100376581C (zh)	2008-03-26
CN101003538A (zh)	2007-07-25
CA2481324A1 (en)	2003-11-06
EP1497296A1 (de)	2005-01-19
US7012089B2 (en)	2006-03-14
AU2003263119B2 (en)	2009-05-07
CN1662539A (zh)	2005-08-31
JP4537076B2 (ja)	2010-09-01
JP2005531538A (ja)	2005-10-20
ES2260631T3 (es)	2006-11-01
AR039668A1 (es)	2005-03-02
TW200307540A (en)	2003-12-16
US20040034005A1 (en)	2004-02-19

Legal Events

Date	Code	Title	Description
2006-09-15	RER	Ceased as to paragraph 5 lit. 3 law introducing patent treaties

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