ATE321534T1 - Verbesserte liposomale formulierung - Google Patents
Verbesserte liposomale formulierungInfo
- Publication number
- ATE321534T1 ATE321534T1 AT96918308T AT96918308T ATE321534T1 AT E321534 T1 ATE321534 T1 AT E321534T1 AT 96918308 T AT96918308 T AT 96918308T AT 96918308 T AT96918308 T AT 96918308T AT E321534 T1 ATE321534 T1 AT E321534T1
- Authority
- AT
- Austria
- Prior art keywords
- liposomal formulation
- improved liposomal
- instability
- improved
- alum
- Prior art date
Links
- 238000009472 formulation Methods 0.000 title abstract 3
- 239000000203 mixture Substances 0.000 title abstract 3
- 229940037003 alum Drugs 0.000 abstract 1
- 239000000427 antigen Substances 0.000 abstract 1
- 102000036639 antigens Human genes 0.000 abstract 1
- 108091007433 antigens Proteins 0.000 abstract 1
- 239000003599 detergent Substances 0.000 abstract 1
- 239000003381 stabilizer Substances 0.000 abstract 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
- G01N33/54313—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being characterised by its particulate form
- G01N33/5432—Liposomes or microcapsules
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
- A61K9/1271—Non-conventional liposomes, e.g. PEGylated liposomes or liposomes coated or grafted with polymers
- A61K9/1272—Non-conventional liposomes, e.g. PEGylated liposomes or liposomes coated or grafted with polymers comprising non-phosphatidyl surfactants as bilayer-forming substances, e.g. cationic lipids or non-phosphatidyl liposomes coated or grafted with polymers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55555—Liposomes; Vesicles, e.g. nanoparticles; Spheres, e.g. nanospheres; Polymers
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S436/00—Chemistry: analytical and immunological testing
- Y10S436/829—Liposomes, e.g. encapsulation
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Immunology (AREA)
- Molecular Biology (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Dispersion Chemistry (AREA)
- Biomedical Technology (AREA)
- Urology & Nephrology (AREA)
- Hematology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Pharmacology & Pharmacy (AREA)
- Physics & Mathematics (AREA)
- Microbiology (AREA)
- Pathology (AREA)
- Biophysics (AREA)
- Biotechnology (AREA)
- Biochemistry (AREA)
- Analytical Chemistry (AREA)
- General Physics & Mathematics (AREA)
- Cell Biology (AREA)
- Food Science & Technology (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Detergent Compositions (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US08/480,563 US5820880A (en) | 1995-06-07 | 1995-06-07 | Liposomal formulation |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE321534T1 true ATE321534T1 (de) | 2006-04-15 |
Family
ID=23908444
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT96918308T ATE321534T1 (de) | 1995-06-07 | 1996-06-06 | Verbesserte liposomale formulierung |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US5820880A (de) |
| EP (1) | EP0831780B1 (de) |
| JP (1) | JPH11507628A (de) |
| AT (1) | ATE321534T1 (de) |
| AU (1) | AU721085B2 (de) |
| CA (1) | CA2221310A1 (de) |
| DE (1) | DE69635987T2 (de) |
| ES (1) | ES2262155T3 (de) |
| WO (1) | WO1996040065A1 (de) |
Families Citing this family (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5902604A (en) * | 1995-06-06 | 1999-05-11 | Board Of Regents, The University Of Texas System | Submicron liposome suspensions obtained from preliposome lyophilizates |
| US7879977B2 (en) | 1998-01-31 | 2011-02-01 | University Of Arkansas | Methods and reagents for decreasing clinical reaction to allergy |
| DE69940805D1 (de) | 1998-01-31 | 2009-06-10 | Sinai School Medicine | Verfahren und reagenzien zur verminderung der klinischen reaktion zur allergie |
| WO2000071711A2 (en) * | 1999-05-20 | 2000-11-30 | Fahri Saatcioglu | Differentially expressed genes in prostate cancer |
| US7189565B2 (en) * | 2001-03-23 | 2007-03-13 | Fahri Saatcioglu | Prostate-specific or testis-specific nucleic acid molecules, polypeptides, and diagnostic and therapeutic methods |
| US7611892B2 (en) * | 2000-03-24 | 2009-11-03 | President And Fellows Of Harvard College | Prostate-specific or testis-specific nucleic acid molecules, polypeptides, and diagnostic and therapeutic methods |
| JP2004521602A (ja) * | 2000-03-24 | 2004-07-22 | ファハリ サッチオグリュ | 前立腺特異的または精巣特異的な新規の核酸分子、ポリペプチド、ならびに診断法および治療法 |
| US8246945B2 (en) * | 2000-04-06 | 2012-08-21 | University Of Arkansas | Methods and reagents for decreasing clinical reaction to allergy |
| US20050063994A1 (en) * | 2000-04-06 | 2005-03-24 | Caplan Michael J. | Methods and reagents for decreasing clinical reaction to allergy |
| EP1272213B1 (de) | 2000-04-06 | 2006-03-08 | SEER Pharmaceuticals, LLC. | Microbielles wirkstoffabgabesystem |
| JP3990880B2 (ja) * | 2001-07-10 | 2007-10-17 | キヤノン株式会社 | ポリヒドロキシアルカノエート被覆リポソームの製造方法 |
| US7279163B1 (en) | 2002-03-21 | 2007-10-09 | The United States Of America, As Represented By The Secretary Of Agriculture | Water-in-oil emulsion vaccines |
| US7914801B1 (en) | 2002-03-21 | 2011-03-29 | The United States Of America As Represented By The Secretary Of Agriculture | Metabolizable oil emulsion adjuvants and vaccines for enhancing immuno-properties of antibodies and their subpopulations |
| AU2003296335A1 (en) * | 2002-12-06 | 2004-06-30 | Board Of Regents, The University Of Texas System | Compositions and methods related to lipid:emodin formulations |
| US20060073196A1 (en) * | 2003-02-12 | 2006-04-06 | Institut National De La Sante Et De La Recherche Medicale (Inserm) | Use of p-glycoprotein inhibitor surfactants at the surface of a colloidal carrier |
| CN102743382B (zh) * | 2005-09-19 | 2016-12-07 | 诺伊罗纳森特公司 | 刺激神经形成和抑制神经元变性的方法和组合物 |
| AU2008265600B2 (en) | 2007-06-21 | 2013-10-31 | Neuronascent, Inc. | Methods and compositions for stimulating neurogenesis and inhibiting neuronal degeneration using isothiazolopyrimidinones |
| WO2009133867A1 (ja) * | 2008-05-01 | 2009-11-05 | 片山化学工業株式会社 | 金属コロイド含有リポソーム |
| US20100260830A1 (en) * | 2009-04-08 | 2010-10-14 | Brian A Salvatore | Liposomal Formulations of Tocopheryl Amides |
| DK3054936T5 (da) | 2013-10-10 | 2024-03-18 | Eastern Virginia Medical School | 4-((2-hydroxy-3-methoxybenzyl)amino) benzensulfonamid derivater som 12-lipoxygenase inhibitorer |
| WO2023056368A1 (en) | 2021-09-30 | 2023-04-06 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Cyclic peptides as non-hormonal male contraceptive agents and methods of use thereof |
| AU2022435102A1 (en) | 2022-01-21 | 2024-07-25 | Elanco Animal Health Gmbh | Molidustat formulations and methods of use for treatment of anemia in cats |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH0753661B2 (ja) * | 1984-03-08 | 1995-06-07 | フアレス フアーマスーチカル リサーチ エヌブイ | プロ―リポソーム組成物及びリポソームの水性分散物を作る方法 |
| US4897269A (en) * | 1984-09-24 | 1990-01-30 | Mezei Associates Limited | Administration of drugs with multiphase liposomal delivery system |
| US5374548A (en) * | 1986-05-02 | 1994-12-20 | Genentech, Inc. | Methods and compositions for the attachment of proteins to liposomes using a glycophospholipid anchor |
| KR900701304A (ko) * | 1988-05-05 | 1990-12-01 | 루이즈 츄이 콜린스 에이미 | 사람 및/또는 동물용 알레르겐 탈감작제 |
| FI925835A0 (fi) * | 1990-06-29 | 1992-12-22 | Chiron Corp | Vacciner innehaollande liposomer |
| JPH06183953A (ja) * | 1991-06-24 | 1994-07-05 | Nippon Oil & Fats Co Ltd | 混合脂質膜小胞 |
| WO1993001831A1 (en) * | 1991-07-25 | 1993-02-04 | Idec Pharmaceuticals Corporation | Induction of cytotoxic t-lymphocyte responses |
| ZA941645B (en) * | 1994-03-09 | 1995-01-13 | South To South Co Operation In | Antibodies specifically reactive against human prostate specific antigen. |
-
1995
- 1995-06-07 US US08/480,563 patent/US5820880A/en not_active Expired - Lifetime
-
1996
- 1996-06-06 CA CA002221310A patent/CA2221310A1/en not_active Abandoned
- 1996-06-06 JP JP9501752A patent/JPH11507628A/ja not_active Ceased
- 1996-06-06 EP EP96918308A patent/EP0831780B1/de not_active Expired - Lifetime
- 1996-06-06 AT AT96918308T patent/ATE321534T1/de not_active IP Right Cessation
- 1996-06-06 DE DE69635987T patent/DE69635987T2/de not_active Expired - Fee Related
- 1996-06-06 WO PCT/US1996/009432 patent/WO1996040065A1/en not_active Ceased
- 1996-06-06 ES ES96918308T patent/ES2262155T3/es not_active Expired - Lifetime
- 1996-06-06 AU AU60997/96A patent/AU721085B2/en not_active Ceased
Also Published As
| Publication number | Publication date |
|---|---|
| EP0831780A1 (de) | 1998-04-01 |
| JPH11507628A (ja) | 1999-07-06 |
| CA2221310A1 (en) | 1996-12-19 |
| AU6099796A (en) | 1996-12-30 |
| US5820880A (en) | 1998-10-13 |
| EP0831780B1 (de) | 2006-03-29 |
| ES2262155T3 (es) | 2006-11-16 |
| EP0831780A4 (de) | 1999-05-19 |
| DE69635987T2 (de) | 2006-11-16 |
| DE69635987D1 (de) | 2006-05-18 |
| AU721085B2 (en) | 2000-06-22 |
| WO1996040065A1 (en) | 1996-12-19 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |