ATE321849T1 - Verfahren zur erkennung von nucleinsäuremolekülen codierend für (poly)peptide, welche mit zielmolekülen interagieren - Google Patents
Verfahren zur erkennung von nucleinsäuremolekülen codierend für (poly)peptide, welche mit zielmolekülen interagierenInfo
- Publication number
- ATE321849T1 ATE321849T1 AT98924190T AT98924190T ATE321849T1 AT E321849 T1 ATE321849 T1 AT E321849T1 AT 98924190 T AT98924190 T AT 98924190T AT 98924190 T AT98924190 T AT 98924190T AT E321849 T1 ATE321849 T1 AT E321849T1
- Authority
- AT
- Austria
- Prior art keywords
- peptides
- interact
- poly
- nucleic acid
- acid molecules
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
- C12N15/1034—Isolating an individual clone by screening libraries
- C12N15/1041—Ribosome/Polysome display, e.g. SPERT, ARM
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Genetics & Genomics (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- General Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Zoology (AREA)
- Molecular Biology (AREA)
- Wood Science & Technology (AREA)
- Biophysics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biotechnology (AREA)
- Biomedical Technology (AREA)
- General Health & Medical Sciences (AREA)
- Physics & Mathematics (AREA)
- Crystallography & Structural Chemistry (AREA)
- Immunology (AREA)
- Plant Pathology (AREA)
- Bioinformatics & Computational Biology (AREA)
- Microbiology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Medicinal Chemistry (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP97106753 | 1997-04-23 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE321849T1 true ATE321849T1 (de) | 2006-04-15 |
Family
ID=8226724
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT98924190T ATE321849T1 (de) | 1997-04-23 | 1998-04-23 | Verfahren zur erkennung von nucleinsäuremolekülen codierend für (poly)peptide, welche mit zielmolekülen interagieren |
Country Status (7)
| Country | Link |
|---|---|
| US (2) | US6348315B1 (de) |
| EP (1) | EP0975748B1 (de) |
| JP (1) | JP4086325B2 (de) |
| AT (1) | ATE321849T1 (de) |
| CA (1) | CA2289691C (de) |
| DE (1) | DE69834032T2 (de) |
| WO (1) | WO1998048008A1 (de) |
Families Citing this family (57)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0975748B1 (de) * | 1997-04-23 | 2006-03-29 | Universität Zürich | Verfahren zur erkennung von nucleinsäuremolekülen codierend für (poly)peptide, welche mit zielmolekülen interagieren |
| CA2302147C (en) * | 1997-09-03 | 2008-05-13 | Biovation Limited | Methods for protein screening |
| US6927025B1 (en) | 1997-09-03 | 2005-08-09 | Biovation Limited | Methods for protein screening |
| US20070166741A1 (en) | 1998-12-14 | 2007-07-19 | Somalogic, Incorporated | Multiplexed analyses of test samples |
| AU4427100A (en) | 1999-05-14 | 2000-12-05 | Enterprise Ireland Trading As Bioresearch Ireland | Nucleic acid probe-based diagnostic assays for prokaryotic and eukaryotic organisms |
| CA2402452A1 (en) * | 2000-03-31 | 2001-10-11 | Cambridge Antibody Technology Limited | Improvements to ribosome display |
| EP1332209B1 (de) | 2000-09-08 | 2009-11-11 | Universität Zürich | Sammlung von proteinen mit sich wiederholenden sequenzen (repeat proteins), die repetitive sequenzmodule enthalten |
| JP4516273B2 (ja) * | 2000-11-15 | 2010-08-04 | ミナーヴァ・バイオテクノロジーズ・コーポレーション | オリゴヌクレオチド識別子 |
| DE10060959A1 (de) * | 2000-12-06 | 2002-06-20 | Aventis Res & Tech Gmbh & Co | Verfahren zur Isolierung und Identifizierung von Effektoren |
| WO2003064604A2 (en) * | 2002-01-25 | 2003-08-07 | The Board Of Trustees Of The Leland Stanford Junior University | Translation profiling |
| US20050123973A1 (en) * | 2002-02-08 | 2005-06-09 | Shaobing Hua | Methods for generating monoclonal antibody against fusion protein containing peptide fragment derived from membrane protein |
| US20040067532A1 (en) | 2002-08-12 | 2004-04-08 | Genetastix Corporation | High throughput generation and affinity maturation of humanized antibody |
| PT1558643E (pt) * | 2002-11-09 | 2009-08-24 | Immunocore Ltd | Apresentação de um receptor das células t |
| GB0316314D0 (en) * | 2003-07-12 | 2003-08-13 | Univ Belfast | Method |
| GB0411771D0 (en) * | 2004-05-26 | 2004-06-30 | Avidex Ltd | Nucleoproteins displaying native T cell receptor libraries |
| BRPI0608281B8 (pt) | 2005-04-18 | 2021-05-25 | Amgen Res Munich Gmbh | anticorpo monoclonal humano ou seu fragmento, seu uso no tratamento de doenças inflamatórias, bem como composição farmacêutica que o compreende |
| US20070111237A1 (en) * | 2005-09-14 | 2007-05-17 | Maurizio Zanetti | Process for identifying antigenized antibodies using ribosome cell free expression system |
| DK2339014T3 (en) | 2005-11-16 | 2015-07-20 | Ambrx Inc | Methods and compositions comprising non-natural amino acids |
| CA2634987C (en) * | 2006-01-17 | 2017-01-03 | Somalogic, Inc. | Multiplexed analyses of test samples |
| AR059448A1 (es) | 2006-02-13 | 2008-04-09 | Divergence Inc | Polipeptidos quimericos vegetales de union para el reconocimiento molecular universal |
| EP1894939A1 (de) * | 2006-09-01 | 2008-03-05 | GSF-Forschungszentrum für Umwelt und Gesundheit GmbH | Neues Supertag und seine Verwendung |
| EP2084528B1 (de) * | 2006-10-20 | 2012-08-29 | Alere Scarborough, Inc. | Tests und vorrichtungen zur identifizierung von krankheitserregern |
| WO2009023184A2 (en) * | 2007-08-10 | 2009-02-19 | Protelix, Inc. | Universal fibronectin type iii binding-domain libraries |
| US8680019B2 (en) * | 2007-08-10 | 2014-03-25 | Protelica, Inc. | Universal fibronectin Type III binding-domain libraries |
| US8470966B2 (en) | 2007-08-10 | 2013-06-25 | Protelica, Inc. | Universal fibronectin type III binding-domain libraries |
| US12529164B2 (en) | 2007-09-14 | 2026-01-20 | Adimab, Llc | Rationally designed, synthetic antibody libraries and uses therefor |
| US8877688B2 (en) | 2007-09-14 | 2014-11-04 | Adimab, Llc | Rationally designed, synthetic antibody libraries and uses therefor |
| EP3124497B1 (de) | 2007-09-14 | 2020-04-15 | Adimab, LLC | Synthetische antikörperbibliotheken mit rationalem design und verwendungen davon |
| RU2396336C2 (ru) * | 2007-09-27 | 2010-08-10 | Закрытое акционерное общество "Научно-исследовательский институт Аджиномото-Генетика" (ЗАО АГРИ) | СПОСОБ ПОЛУЧЕНИЯ АМИНОКИСЛОТ С ИСПОЛЬЗОВАНИЕМ БАКТЕРИИ, ПРИНАДЛЕЖАЩЕЙ К РОДУ Escherichia |
| US8420081B2 (en) | 2007-11-30 | 2013-04-16 | Abbvie, Inc. | Antibody formulations and methods of making same |
| US8883146B2 (en) | 2007-11-30 | 2014-11-11 | Abbvie Inc. | Protein formulations and methods of making same |
| US8865179B2 (en) * | 2008-01-26 | 2014-10-21 | Swey-Shen Alexchen | Aptameric IgE peptides in a protein scaffold as an allergy vaccine |
| EP2088432A1 (de) * | 2008-02-11 | 2009-08-12 | MorphoSys AG | Verfahren zur Identifikation eines Antikörpers oder eines Targets |
| EP2316030B1 (de) | 2008-07-25 | 2019-08-21 | Wagner, Richard W. | Proteinscreeningverfahren |
| BRPI0921469B1 (pt) | 2008-11-03 | 2022-01-18 | Molecular Partners Ag | Proteínas de ligação que inibem a interação com o receptor de vegf-a, composição farmacêutica |
| ES2691717T3 (es) | 2009-10-30 | 2018-11-28 | Novartis Ag | Bibliotecas universales del dominio de unión del lado inferior de tipo iii de la fibronectina de tipo III |
| WO2011111832A1 (ja) | 2010-03-11 | 2011-09-15 | 独立行政法人理化学研究所 | ポリペプチド配列の選択方法、並びに金属酸化物または含珪素化合物結合ペプチドおよびその利用 |
| AR081361A1 (es) | 2010-04-30 | 2012-08-29 | Molecular Partners Ag | Proteinas de union modificadas que inhiben la interaccion de receptor del factor de crecimiento endotelial vascular de glicoproteina a vegf-a |
| KR102318383B1 (ko) | 2010-07-16 | 2021-10-27 | 아디맵 엘엘씨 | 항체 라이브러리 |
| CN107903321A (zh) | 2010-07-30 | 2018-04-13 | 诺华有限公司 | 纤连蛋白摇篮分子和其库 |
| PL2643349T3 (pl) | 2010-11-26 | 2020-03-31 | Molecular Partners Ag | Zaprojektowane białka z powtórzeniami wiążące się z albuminą surowicy |
| JP5948673B2 (ja) | 2011-03-10 | 2016-07-06 | ジーンフロンティア株式会社 | リポ多糖混入量を低減した蛋白質合成用組成物、該組成物を用いた蛋白質製造方法 |
| ES2926988T3 (es) | 2011-03-15 | 2022-10-31 | X Body Inc | Métodos de cribado de anticuerpos |
| CN103732738A (zh) | 2011-04-28 | 2014-04-16 | 小利兰斯坦福大学托管委员会 | 与样品相关的多核苷酸的鉴定 |
| EA201391607A1 (ru) | 2011-04-29 | 2014-04-30 | Янссен Байотек, Инк. | Связывающие il4/il13 белки с повторами и их применение |
| JP6057297B2 (ja) | 2011-05-23 | 2017-01-11 | 国立研究開発法人理化学研究所 | 核酸構築物、核酸−蛋白質複合体、及びその利用 |
| AU2012347972B2 (en) | 2011-12-05 | 2018-05-10 | X-Body, Inc. | PDGF receptor beta binding polypeptides |
| IN2014DN08778A (de) | 2012-03-27 | 2015-05-22 | Green Cross Corp | |
| WO2014001442A1 (en) | 2012-06-28 | 2014-01-03 | Molecular Partners Ag | Designed ankyrin repeat proteins binding to platelet-derived growth factor |
| EP2738180A1 (de) | 2012-11-30 | 2014-06-04 | Molecular Partners AG | Bindeproteine mit mindestens zwei Bindedomänen gegen HER2 |
| EP2989202B1 (de) | 2013-04-25 | 2019-04-10 | Sutro Biopharma, Inc. | Die verwendung des lambda-gam proteins in der ribosomen-display-technologie |
| US20160069897A1 (en) | 2013-04-25 | 2016-03-10 | Suthro Biopharma, Inc. | Selection of fab fragments using ribosomal display technology |
| MY191368A (en) | 2013-06-28 | 2022-06-20 | X Body Inc | Target antigen discovery, phenotypic screens and use thereof for identification of target cell specific target epitopes |
| EP3779440A1 (de) | 2013-09-23 | 2021-02-17 | X-Body, Inc. | Verfahren und zusammensetzungen zur erzeugung von bindemitteln gegen zelloberflächenantigene |
| EP3080158A4 (de) | 2013-12-09 | 2018-03-21 | Adimab, LLC | Polyklonale antikörpermischungen sowie verfahren zur herstellung und verwendung davon |
| JP6962819B2 (ja) | 2015-04-10 | 2021-11-05 | アディマブ, エルエルシー | 親ホモ二量体抗体種からのヘテロ二量体多重特異性抗体の精製方法 |
| WO2026060324A1 (en) | 2024-09-13 | 2026-03-19 | Ormoni Biosciences, Inc. | Peptide libraries having improved functional pharmacokinetic parameters and methods of synthesis and use thereof |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU638762B2 (en) * | 1989-10-05 | 1993-07-08 | Optein Inc | Cell-free synthesis and isolation of novel genes and polypeptides |
| WO1993003172A1 (en) * | 1991-08-01 | 1993-02-18 | University Research Corporation | Systematic polypeptide evolution by reverse translation |
| US5466580A (en) * | 1993-09-22 | 1995-11-14 | Xoma Corporation | Method for quantifying BPI in body fluids |
| US5922545A (en) * | 1993-10-29 | 1999-07-13 | Affymax Technologies N.V. | In vitro peptide and antibody display libraries |
| WO1995011922A1 (en) * | 1993-10-29 | 1995-05-04 | Affymax Technologies N.V. | In vitro peptide and antibody display libraries |
| EP0975748B1 (de) * | 1997-04-23 | 2006-03-29 | Universität Zürich | Verfahren zur erkennung von nucleinsäuremolekülen codierend für (poly)peptide, welche mit zielmolekülen interagieren |
-
1998
- 1998-04-23 EP EP98924190A patent/EP0975748B1/de not_active Expired - Lifetime
- 1998-04-23 AT AT98924190T patent/ATE321849T1/de active
- 1998-04-23 JP JP54503898A patent/JP4086325B2/ja not_active Expired - Fee Related
- 1998-04-23 WO PCT/EP1998/002420 patent/WO1998048008A1/en not_active Ceased
- 1998-04-23 DE DE69834032T patent/DE69834032T2/de not_active Expired - Lifetime
- 1998-04-23 CA CA002289691A patent/CA2289691C/en not_active Expired - Fee Related
-
1999
- 1999-10-22 US US09/425,585 patent/US6348315B1/en not_active Expired - Lifetime
-
2001
- 2001-09-14 US US09/953,321 patent/US6589741B2/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| CA2289691A1 (en) | 1998-10-29 |
| EP0975748A1 (de) | 2000-02-02 |
| US6348315B1 (en) | 2002-02-19 |
| WO1998048008A1 (en) | 1998-10-29 |
| US20020115083A1 (en) | 2002-08-22 |
| DE69834032D1 (de) | 2006-05-18 |
| EP0975748B1 (de) | 2006-03-29 |
| JP4086325B2 (ja) | 2008-05-14 |
| US6589741B2 (en) | 2003-07-08 |
| DE69834032T2 (de) | 2006-12-07 |
| CA2289691C (en) | 2008-01-15 |
| JP2001521395A (ja) | 2001-11-06 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification |
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