ATE323110T1 - Verfahren zur herstellung von einem cyclodextrin - Google Patents

Verfahren zur herstellung von einem cyclodextrin

Info

Publication number: ATE323110T1
Authority: AT; Austria
Prior art keywords: cyclodextrin; base; residual; alkyl sultone; added
Prior art date: 1997-07-01

Application number

AT98304785T

Other languages

English (en)

Inventor

Constantine Sklavounos

Bharat Kiritkumar Shah

Original Assignee

Pfizer Prod Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1997-07-01

Filing date

1998-06-17

Publication date

2006-04-15

1998-06-17 Application filed by Pfizer Prod Inc filed Critical Pfizer Prod Inc

2006-04-15 Application granted granted Critical

2006-04-15 Publication of ATE323110T1 publication Critical patent/ATE323110T1/de

Links

229920000858 Cyclodextrin Polymers 0.000 title abstract 5
HFHDHCJBZVLPGP-UHFFFAOYSA-N schardinger α-dextrin Chemical compound O1C(C(C2O)O)C(CO)OC2OC(C(C2O)O)C(CO)OC2OC(C(C2O)O)C(CO)OC2OC(C(O)C2O)C(CO)OC2OC(C(C2O)O)C(CO)OC2OC2C(O)C(O)C1OC2CO HFHDHCJBZVLPGP-UHFFFAOYSA-N 0.000 title abstract 4
238000004519 manufacturing process Methods 0.000 title 1
-1 Sulfoalkyl ether Chemical compound 0.000 abstract 4
239000007858 starting material Substances 0.000 abstract 2
229940097362 cyclodextrins Drugs 0.000 abstract 1
RTZKZFJDLAIYFH-UHFFFAOYSA-N ether Substances CCOCC RTZKZFJDLAIYFH-UHFFFAOYSA-N 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
- C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
- C08B37/0006—Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid
- C08B37/0009—Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid alpha-D-Glucans, e.g. polydextrose, alternan, glycogen; (alpha-1,4)(alpha-1,6)-D-Glucans; (alpha-1,3)(alpha-1,4)-D-Glucans, e.g. isolichenan or nigeran; (alpha-1,4)-D-Glucans; (alpha-1,3)-D-Glucans, e.g. pseudonigeran; Derivatives thereof
- C08B37/0012—Cyclodextrin [CD], e.g. cycle with 6 units (alpha), with 7 units (beta) and with 8 units (gamma), large-ring cyclodextrin or cycloamylose with 9 units or more; Derivatives thereof

Landscapes

Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Health & Medical Sciences (AREA)
Biochemistry (AREA)
Molecular Biology (AREA)
Engineering & Computer Science (AREA)
General Health & Medical Sciences (AREA)
Materials Engineering (AREA)
Chemical Kinetics & Catalysis (AREA)
Medicinal Chemistry (AREA)
Polymers & Plastics (AREA)
Organic Chemistry (AREA)
Polysaccharides And Polysaccharide Derivatives (AREA)

AT98304785T 1997-07-01 1998-06-17 Verfahren zur herstellung von einem cyclodextrin ATE323110T1 (de)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US5149797P	1997-07-01	1997-07-01

Publications (1)

Publication Number	Publication Date
ATE323110T1 true ATE323110T1 (de)	2006-04-15

Family

ID=21971666

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT98304785T ATE323110T1 (de)	1997-07-01	1998-06-17	Verfahren zur herstellung von einem cyclodextrin

Country Status (10)

Country	Link
US (1)	US6153746A (de)
EP (1)	EP0889056B1 (de)
JP (1)	JP3272669B2 (de)
AT (1)	ATE323110T1 (de)
BR (1)	BR9802331A (de)
CA (1)	CA2241774C (de)
DE (1)	DE69834154T2 (de)
DK (1)	DK0889056T3 (de)
ES (1)	ES2257795T3 (de)
PT (1)	PT889056E (de)

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JP2004531537A (ja) *	2001-05-01	2004-10-14	ファイザー・プロダクツ・インク	一様な薬剤分布と効力を有する低用量製薬組成物の製造方法
CN101039682A (zh) *	2003-10-31	2007-09-19	堪萨斯大学	磺基烷基醚－烷基醚环糊精衍生物
US20070020299A1 (en)	2003-12-31	2007-01-25	Pipkin James D	Inhalant formulation containing sulfoalkyl ether cyclodextrin and corticosteroid
AU2004311478A1 (en)	2003-12-31	2005-07-21	Cydex Pharmaceuticals, Inc.	Inhalant formulation containing sulfoalkyl ether cyclodextrin and corticosteroid
CN101098678A (zh)	2004-04-23	2008-01-02	锡德克斯公司	含有磺基烷基醚环糊精的dpi制剂
US20100204178A1 (en)	2006-10-02	2010-08-12	James Cloyd	Novel parenteral carbamazepine formulation
PT2583668E (pt)	2005-10-26	2015-01-05	Cydex Pharmaceuticals Inc	Composições de éter sulfoalquílico de ciclodextrina e métodos para a sua preparação
AU2011204957B2 (en) *	2005-10-26	2013-12-05	Cydex Pharmaceuticals, Inc	Sulfoalkyl ether cyclodextrin compositions and methods of preparation thereof
US7629331B2 (en)	2005-10-26	2009-12-08	Cydex Pharmaceuticals, Inc.	Sulfoalkyl ether cyclodextrin compositions and methods of preparation thereof
CN102327617B (zh) *	2005-10-26	2014-08-20	锡德克斯药物公司	磺基烷基醚环糊精组合物和其制备方法
RU2417103C2 (ru) *	2005-10-26	2011-04-27	Сайдекс Фармасьютикалз, Инк.	Композиции простого сульфоалкилового эфира циклодекстрина и способы их получения
US20090239942A1 (en) *	2006-09-15	2009-09-24	Cloyd James C	Topiramate Compositions and Methods of Making and Using the Same
WO2008065142A1 (en) *	2006-11-29	2008-06-05	N.V. Organon	Stabilized solution of rocuronium comprising a sulfoalkyl-ether-beta-cyclodextrin derivative
JP5681485B2 (ja)	2007-04-27	2015-03-11	サイデックス・ファーマシューティカルズ・インコーポレイテッド	クロピドグレルおよびスルホアルキルエーテルシクロデキストリンを含有する製剤ならびに使用方法
US12370352B2 (en)	2007-06-28	2025-07-29	Cydex Pharmaceuticals, Inc.	Nasal and ophthalmic delivery of aqueous corticosteroid solutions
ES2493641T3 (es) *	2007-06-28	2014-09-12	Cydex Pharmaceuticals, Inc.	Administración nasal de soluciones acuosas de corticosteroides
US7635773B2 (en)	2008-04-28	2009-12-22	Cydex Pharmaceuticals, Inc.	Sulfoalkyl ether cyclodextrin compositions
EP3090737A1 (de)	2008-10-21	2016-11-09	Onyx Therapeutics, Inc.	Kombinationstherapie mit peptidepoxyketonen
US10463677B2 (en)	2008-11-07	2019-11-05	Cydex Pharmaceuticals, Inc.	Composition containing sulfoalkyl ether cyclodextrin and latanoprost
CA2761455C (en)	2009-05-13	2018-06-12	Cydex Pharmaceuticals, Inc.	Pharmaceutical compositions comprising prasugrel and cyclodextrin derivatives and methods of making and using the same
US11020363B2 (en)	2009-05-29	2021-06-01	Cydex Pharmaceuticals, Inc.	Injectable nitrogen mustard compositions comprising a cyclodextrin derivative and methods of making and using the same
PL2434886T3 (pl)	2009-05-29	2020-05-18	Cydex Pharmaceuticals, Inc.	Kompozycje do wstrzykiwania melfalanu zawierające pochodną cyklodekstryny i sposoby ich wytwarzania i stosowania
US8492538B1 (en)	2009-06-04	2013-07-23	Jose R. Matos	Cyclodextrin derivative salts
TWI544922B (zh)	2011-05-19	2016-08-11	愛爾康研究有限公司	高濃度歐羅派特錠（ｏｌｏｐａｔａｄｉｎｅ）眼用組成物
TW201336527A (zh)	2012-02-10	2013-09-16	Alcon Res Ltd	具增強的穩定性之水性藥學組成物
WO2013123254A1 (en)	2012-02-15	2013-08-22	Cydex Pharmaceuticals, Inc.	Manufacturing process for cyclodextrin derivatives
RU2615385C2 (ru) *	2012-02-28	2017-04-04	Сидекс Фармасьютикалс, Инк.	Композиции алкилированного циклодекстрина и способы их получения и применения
KR101905937B1 (ko) *	2012-03-30	2018-10-08	자피오텍 게엠베하	안토시아니딘 복합체
SG11201407337QA (en)	2012-05-08	2014-12-30	Onyx Therapeutics Inc	Cyclodextrin complexation methods for formulating peptide proteasome inhibitors
KR102112119B1 (ko)	2012-10-22	2020-05-19	사이덱스 파마슈티칼스, 인크.	알킬화된 시클로덱스트린 조성물 및 이의 제조 및 사용 방법
GB201312737D0 (en) *	2013-07-17	2013-08-28	Univ Greenwich	Cyclodextrin
CN103694376B (zh) *	2014-01-10	2016-04-13	凯莱英医药集团（天津）股份有限公司	一种制备磺丁基醚-β-环糊精的方法
PT3183295T (pt)	2014-08-22	2023-11-03	Cydex Pharmaceuticals Inc	Composições de ciclodextrina alquilada fracionada e processos para preparação e utilização das mesmas
CA2980170A1 (en)	2015-03-19	2016-09-22	Cydex Pharmaceuticals, Inc.	Compositions containing silymarin and sulfoalkyl ether cyclodextrin and methods of using the same
CN104892797B (zh) *	2015-05-28	2017-03-22	天津大学	特定平均取代度磺丁基醚‑β‑环糊精的合成方法
CN106749770A (zh) *	2015-11-20	2017-05-31	天津市通航科技有限公司	一种微波辐射/碱耦合制备不同取代度磺丁基醚-β-环糊精的方法
WO2018146698A1 (en)	2017-02-07	2018-08-16	Biophore India Pharmaceuticals Pvt. Ltd.	Improved method for the preparation of sulfobutylether beta cyclodextrin sodium
JP7204670B2 (ja)	2017-05-03	2023-01-16	サイデックス・ファーマシューティカルズ・インコーポレイテッド	シクロデキストリン及びブスルファンを含有する組成物
JP7336657B2 (ja)	2018-10-15	2023-09-01	国立大学法人大阪大学	環状オリゴ糖及びその製造方法
CN115038723A (zh) *	2019-11-18	2022-09-09	锡德克斯药物公司	烷基化环糊精组合物及其制备和使用方法
JP2023551145A (ja)	2020-11-18	2023-12-07	ベクソンバイオメディカル，インク．	医薬化合物の錯化剤塩製剤

Family Cites Families (4)

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Publication number	Priority date	Publication date	Assignee	Title
US3426011A (en) *	1967-02-13	1969-02-04	Corn Products Co	Cyclodextrins with anionic properties
KR0166088B1 (ko) *	1990-01-23	1999-01-15	.	수용해도가 증가된 시클로덱스트린 유도체 및 이의 용도
US5376645A (en) *	1990-01-23	1994-12-27	University Of Kansas	Derivatives of cyclodextrins exhibiting enhanced aqueous solubility and the use thereof
US5681828A (en)	1995-12-19	1997-10-28	Pitha; Josef	Selective alkylations of cyclodextrins leading to derivatives which have a rigidly extended cavity

1998
- 1998-06-17 EP EP98304785A patent/EP0889056B1/de not_active Expired - Lifetime
- 1998-06-17 ES ES98304785T patent/ES2257795T3/es not_active Expired - Lifetime
- 1998-06-17 DK DK98304785T patent/DK0889056T3/da active
- 1998-06-17 DE DE69834154T patent/DE69834154T2/de not_active Expired - Lifetime
- 1998-06-17 PT PT98304785T patent/PT889056E/pt unknown
- 1998-06-17 AT AT98304785T patent/ATE323110T1/de active
- 1998-06-25 JP JP17883198A patent/JP3272669B2/ja not_active Expired - Lifetime
- 1998-06-29 US US09/106,983 patent/US6153746A/en not_active Expired - Lifetime
- 1998-06-29 CA CA002241774A patent/CA2241774C/en not_active Expired - Lifetime
- 1998-07-01 BR BR9802331-4A patent/BR9802331A/pt not_active IP Right Cessation

Also Published As

Publication number	Publication date
PT889056E (pt)	2006-07-31
EP0889056A3 (de)	1999-04-07
EP0889056A2 (de)	1999-01-07
DE69834154T2 (de)	2007-01-25
BR9802331A (pt)	2000-09-05
CA2241774C (en)	2002-06-25
DK0889056T3 (da)	2006-07-17
ES2257795T3 (es)	2006-08-01
DE69834154D1 (de)	2006-05-24
US6153746A (en)	2000-11-28
JPH1160610A (ja)	1999-03-02
JP3272669B2 (ja)	2002-04-08
CA2241774A1 (en)	1999-01-01
EP0889056B1 (de)	2006-04-12

Legal Events

Date

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Title

Description

2006-12-15

UEP

Publication of translation of european patent specification

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