ATE325629T1 - Poröses keramisches/poröses mehrschichtiges polymergerüst zur reparatur und regeneration von gewebe - Google Patents

Poröses keramisches/poröses mehrschichtiges polymergerüst zur reparatur und regeneration von gewebe

Info

Publication number
ATE325629T1
ATE325629T1 AT02254457T AT02254457T ATE325629T1 AT E325629 T1 ATE325629 T1 AT E325629T1 AT 02254457 T AT02254457 T AT 02254457T AT 02254457 T AT02254457 T AT 02254457T AT E325629 T1 ATE325629 T1 AT E325629T1
Authority
AT
Austria
Prior art keywords
porous
regeneration
tissue repair
ceramic
scaffold
Prior art date
Application number
AT02254457T
Other languages
English (en)
Inventor
Kelly R Brown
Jenny J Yuan
Yufu Li
Mark C Zimmermann
Original Assignee
Ethicon Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ethicon Inc filed Critical Ethicon Inc
Application granted granted Critical
Publication of ATE325629T1 publication Critical patent/ATE325629T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/56—Porous materials, e.g. foams or sponges
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/40—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material
    • A61L27/42—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material having an inorganic matrix
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/40—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material
    • A61L27/42—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material having an inorganic matrix
    • A61L27/425—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material having an inorganic matrix of phosphorus containing material, e.g. apatite
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/40—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material
    • A61L27/44—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material having a macromolecular matrix

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Transplantation (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Dermatology (AREA)
  • Composite Materials (AREA)
  • Materials Engineering (AREA)
  • Engineering & Computer Science (AREA)
  • Inorganic Chemistry (AREA)
  • Dispersion Chemistry (AREA)
  • Materials For Medical Uses (AREA)
  • Filtering Materials (AREA)
  • Prostheses (AREA)
  • Manufacture Of Porous Articles, And Recovery And Treatment Of Waste Products (AREA)
  • Solid-Sorbent Or Filter-Aiding Compositions (AREA)
  • Laminated Bodies (AREA)
AT02254457T 2001-06-27 2002-06-26 Poröses keramisches/poröses mehrschichtiges polymergerüst zur reparatur und regeneration von gewebe ATE325629T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US09/892,993 US20030003127A1 (en) 2001-06-27 2001-06-27 Porous ceramic/porous polymer layered scaffolds for the repair and regeneration of tissue

Publications (1)

Publication Number Publication Date
ATE325629T1 true ATE325629T1 (de) 2006-06-15

Family

ID=25400848

Family Applications (1)

Application Number Title Priority Date Filing Date
AT02254457T ATE325629T1 (de) 2001-06-27 2002-06-26 Poröses keramisches/poröses mehrschichtiges polymergerüst zur reparatur und regeneration von gewebe

Country Status (10)

Country Link
US (1) US20030003127A1 (de)
EP (2) EP1604696A1 (de)
JP (1) JP2003126237A (de)
AT (1) ATE325629T1 (de)
AU (1) AU784287B2 (de)
CA (1) CA2391464A1 (de)
DE (1) DE60211251T2 (de)
DK (1) DK1270025T3 (de)
ES (1) ES2262759T3 (de)
PT (1) PT1270025E (de)

Families Citing this family (116)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7763769B2 (en) * 2001-02-16 2010-07-27 Kci Licensing, Inc. Biocompatible wound dressing
US7700819B2 (en) 2001-02-16 2010-04-20 Kci Licensing, Inc. Biocompatible wound dressing
AU2002345328A1 (en) 2001-06-27 2003-03-03 Remon Medical Technologies Ltd. Method and device for electrochemical formation of therapeutic species in vivo
US7371258B2 (en) * 2001-10-26 2008-05-13 St. Jude Medical, Inc. Valved prosthesis with porous substrate
US6792396B2 (en) * 2002-03-28 2004-09-14 Ge Medical Systems Information Technologies, Inc. Interface device and method for a monitoring network
US8187326B2 (en) * 2002-05-22 2012-05-29 Advanced Technologies And Regenerative Medicine, Llc. Attachment of absorbable tissue scaffolds to fixation devices
US6958078B2 (en) * 2002-08-19 2005-10-25 The University Of Toledo Bioartificial intervertebral disc
AU2003289197A1 (en) * 2002-12-06 2004-06-30 National Institute Of Advanced Industrial Science And Technology Graft for regenerating bone-cartilage tissue
ES2405080T3 (es) * 2003-02-26 2013-05-30 Zimmer Orthobiologics, Inc. Preparado para la reparación de un tejido cartilaginoso, en particular de defectos de cartílagos articulares
WO2004098456A2 (en) * 2003-05-01 2004-11-18 Therics, Inc. Porous biostructure partially occupied by interpenetrant and method for making same
ES2595512T3 (es) * 2003-06-25 2016-12-30 Biedermann Technologies Gmbh & Co. Kg Diseño de integración de tejidos para fijación de implantes sin soldadura
US8529625B2 (en) * 2003-08-22 2013-09-10 Smith & Nephew, Inc. Tissue repair and replacement
US7309232B2 (en) * 2003-10-10 2007-12-18 Dentigenix Inc. Methods for treating dental conditions using tissue scaffolds
US7666230B2 (en) * 2003-12-08 2010-02-23 Depuy Products, Inc. Implant device for cartilage regeneration in load bearing articulation regions
US20080089933A1 (en) 2006-10-16 2008-04-17 Amir Alon Device and method for reducing calorie intake
WO2005086706A2 (en) * 2004-03-05 2005-09-22 The Trustees Of Columbia University In The City Of New York Multi-phased, biodegradable and osteointegrative composite scaffold for biological fixation of musculoskeletal soft tissue to bone
US20060036331A1 (en) * 2004-03-05 2006-02-16 Lu Helen H Polymer-ceramic-hydrogel composite scaffold for osteochondral repair
CA2566765C (en) * 2004-05-11 2011-08-23 Synthasome Inc. Hybrid tissue scaffolds containing extracellular matrix
US7758892B1 (en) * 2004-05-20 2010-07-20 Boston Scientific Scimed, Inc. Medical devices having multiple layers
US20100112028A1 (en) * 2004-06-09 2010-05-06 Klaus Hellerbrand Composite material for use as protein carrier
US9763788B2 (en) 2005-09-09 2017-09-19 Board Of Trustees Of The University Of Arkansas Bone regeneration using biodegradable polymeric nanocomposite materials and applications of the same
EP1931401A2 (de) 2005-09-09 2008-06-18 University of Arkansas at Little Rock System und verfahren für die gewebegeneration und knochenregeneration
US8936805B2 (en) 2005-09-09 2015-01-20 Board Of Trustees Of The University Of Arkansas Bone regeneration using biodegradable polymeric nanocomposite materials and applications of the same
EP1764117A1 (de) 2005-09-20 2007-03-21 Zimmer GmbH Implantat zur Wiederherstellung von Knorpeldefekten und Verfahren zu seiner Herstellung
DE102005054937A1 (de) * 2005-11-17 2007-05-24 Gelita Ag Angiogenese förderndes Substrat
US8840660B2 (en) * 2006-01-05 2014-09-23 Boston Scientific Scimed, Inc. Bioerodible endoprostheses and methods of making the same
US8089029B2 (en) * 2006-02-01 2012-01-03 Boston Scientific Scimed, Inc. Bioabsorbable metal medical device and method of manufacture
US20070224244A1 (en) * 2006-03-22 2007-09-27 Jan Weber Corrosion resistant coatings for biodegradable metallic implants
US8048150B2 (en) * 2006-04-12 2011-11-01 Boston Scientific Scimed, Inc. Endoprosthesis having a fiber meshwork disposed thereon
EP1878450A1 (de) * 2006-07-10 2008-01-16 Ecole Polytechnique Federale De Lausanne (Epfl) Polymerkomposit mit einem Porengradient
EP2054537A2 (de) 2006-08-02 2009-05-06 Boston Scientific Scimed, Inc. Endoprothese mit dreidimensionaler desintegrationssteuerung
EP2596764B1 (de) 2006-08-22 2016-07-13 Mitsubishi Electric Corporation Laserverarbeitungsvorrichtung, Ossalintegrationsverfahren, Implantatmaterial und Implantatmaterialherstellungsverfahren
US8449622B2 (en) * 2006-09-11 2013-05-28 Warsaw Orthopedic, Inc. Multi-phase osteochondral implantable device
JP2010503494A (ja) 2006-09-15 2010-02-04 ボストン サイエンティフィック リミテッド 生分解性内部人工器官およびその製造方法
EP2959925B1 (de) * 2006-09-15 2018-08-29 Boston Scientific Limited Medizinische vorrichtungen und verfahren zu ihrer herstellung
EP2121068B1 (de) * 2006-09-15 2010-12-08 Boston Scientific Scimed, Inc. Biologisch erodierbare endoprothese mit biostabilen anorganischen schichten
CA2663250A1 (en) * 2006-09-15 2008-03-20 Boston Scientific Limited Bioerodible endoprostheses and methods of making the same
US8002821B2 (en) * 2006-09-18 2011-08-23 Boston Scientific Scimed, Inc. Bioerodible metallic ENDOPROSTHESES
WO2008036457A2 (en) * 2006-09-18 2008-03-27 Boston Scientific Limited Controlling biodegradation of a medical instrument
CA2674195A1 (en) * 2006-12-28 2008-07-10 Boston Scientific Limited Bioerodible endoprostheses and methods of making same
EP1964583A1 (de) 2007-02-09 2008-09-03 Royal College of Surgeons in Ireland Verfahren zur Herstellung eines Kollagen/Hydroxyapatitverbundgerüsts
US20100167401A1 (en) * 2007-03-19 2010-07-01 Vasif Hasirci Stacked, patterned biomaterials and/or tissue engineering scaffolds
US7750371B2 (en) * 2007-04-30 2010-07-06 International Business Machines Corporation Silicon germanium heterojunction bipolar transistor structure and method
US7900167B2 (en) * 2007-10-24 2011-03-01 International Business Machines Corporation Silicon germanium heterojunction bipolar transistor structure and method
US8052745B2 (en) * 2007-09-13 2011-11-08 Boston Scientific Scimed, Inc. Endoprosthesis
US20090143855A1 (en) * 2007-11-29 2009-06-04 Boston Scientific Scimed, Inc. Medical Device Including Drug-Loaded Fibers
US20100008970A1 (en) * 2007-12-14 2010-01-14 Boston Scientific Scimed, Inc. Drug-Eluting Endoprosthesis
US9782300B2 (en) * 2008-02-01 2017-10-10 Kci Licensing, Inc. Fiber-microsphere bioresorbable composite scaffold for wound healing
EP2273952B1 (de) * 2008-04-02 2018-02-21 Pioneer Surgical Technology, Inc. Bandscheibenimplantatvorrichtungen zur unterstützung der wirbel und vorrichtungen zu ihrer einführung
US7998192B2 (en) * 2008-05-09 2011-08-16 Boston Scientific Scimed, Inc. Endoprostheses
US8236046B2 (en) 2008-06-10 2012-08-07 Boston Scientific Scimed, Inc. Bioerodible endoprosthesis
US20100004733A1 (en) * 2008-07-02 2010-01-07 Boston Scientific Scimed, Inc. Implants Including Fractal Structures
US7985252B2 (en) * 2008-07-30 2011-07-26 Boston Scientific Scimed, Inc. Bioerodible endoprosthesis
US9616205B2 (en) 2008-08-13 2017-04-11 Smed-Ta/Td, Llc Drug delivery implants
US9700431B2 (en) 2008-08-13 2017-07-11 Smed-Ta/Td, Llc Orthopaedic implant with porous structural member
CA2734254C (en) 2008-08-13 2018-06-05 Smed-Ta/Td, Llc Orthopaedic screws
WO2010019781A1 (en) 2008-08-13 2010-02-18 Smed-Ta/Td, Llc Drug delivery implants
US10842645B2 (en) 2008-08-13 2020-11-24 Smed-Ta/Td, Llc Orthopaedic implant with porous structural member
WO2010025386A1 (en) 2008-08-29 2010-03-04 Smed-Ta/Td, Llc Orthopaedic implant
US8382824B2 (en) * 2008-10-03 2013-02-26 Boston Scientific Scimed, Inc. Medical implant having NANO-crystal grains with barrier layers of metal nitrides or fluorides
US8815971B2 (en) 2008-12-22 2014-08-26 ATRP Solutions, Inc. Control over controlled radical polymerization processes
US8822610B2 (en) 2008-12-22 2014-09-02 ATRP Solutions, Inc. Control over controlled radical polymerization processes
MY159533A (en) 2009-01-02 2017-01-13 Univ Putra Malaysia Porous bioceramic composition for bone repair
EP2389204B1 (de) 2009-01-23 2019-07-03 Royal College of Surgeons in Ireland Geschichtetes gerüst, das zur osteochondralen reparatur geeignet ist
FI20095084A0 (fi) 2009-01-30 2009-01-30 Pekka Vallittu Komposiitti ja sen käyttö
WO2010099463A2 (en) 2009-02-27 2010-09-02 University Of Pittsburgh-Of The Commonwealth System Of Higher Education Joint bioscaffolds
US8267992B2 (en) * 2009-03-02 2012-09-18 Boston Scientific Scimed, Inc. Self-buffering medical implants
US9783628B2 (en) 2009-04-23 2017-10-10 ATRP Solutions, Inc. Dual-mechanism thickening agents for hydraulic fracturing fluids
WO2010123574A1 (en) 2009-04-23 2010-10-28 Atrp Solutions Inc Star macromolecules for personal and home care
US8173750B2 (en) 2009-04-23 2012-05-08 ATRP Solutions, Inc. Star macromolecules for personal and home care
WO2010146574A1 (en) * 2009-06-15 2010-12-23 Cartiheal (2009) Ltd. Solid forms for tissue repair
US20110022158A1 (en) * 2009-07-22 2011-01-27 Boston Scientific Scimed, Inc. Bioerodible Medical Implants
US9399086B2 (en) 2009-07-24 2016-07-26 Warsaw Orthopedic, Inc Implantable medical devices
WO2011119573A1 (en) * 2010-03-23 2011-09-29 Boston Scientific Scimed, Inc. Surface treated bioerodible metal endoprostheses
WO2011123110A1 (en) * 2010-03-30 2011-10-06 Daniel Sunho Oh Method of preparing ceramic/polymer composite scaffolds with bioactive molecules for hard tissue regeneration
US9587064B2 (en) 2010-12-08 2017-03-07 ATRP Solutions, Inc. Salt-tolerant star macromolecules
JP2014506509A (ja) * 2011-02-14 2014-03-17 バイオメット、マニュファクチュアリング、リミテッド、ライアビリティ、カンパニー 非再吸収性ポリマー‐セラミック複合インプラント材料
EP2529764A1 (de) 2011-05-31 2012-12-05 Curasan AG Biologisch degradierbares kompositmaterial
US8663539B1 (en) 2012-04-02 2014-03-04 Hrl Laboratories, Llc Process of making a three-dimentional micro-truss structure
CN105189643B (zh) 2012-08-30 2019-01-15 派诺聚合物技术公司 用于水力压裂液的双重机制增稠剂
WO2014040059A1 (en) * 2012-09-10 2014-03-13 Kim Keun-Young Anthony Stimulating bone growth and controlling spinal cord pain
CN102940904B (zh) * 2012-11-26 2014-04-30 西安工程大学 一种针织成型技术制备骨移植材料的方法
EP2951220B1 (de) 2013-02-04 2020-11-25 Pilot Polymer Technologies, Inc. Salztolerante sternmakromoleküle
CN107075015B (zh) 2014-07-03 2019-08-23 派诺聚合物技术公司 表面活性剂-相容性星形大分子
WO2016134866A1 (de) * 2015-02-24 2016-09-01 botiss biomaterials GmbH Kollagenhaltige wundauflage sowie verfahren zu deren herstellung
EP3288501B1 (de) 2015-04-29 2020-11-25 Institute For Musculoskeletal Science And Education, Ltd. Spulenimplantate
US10492921B2 (en) 2015-04-29 2019-12-03 Institute for Musculoskeletal Science and Education, Ltd. Implant with arched bone contacting elements
US10709570B2 (en) 2015-04-29 2020-07-14 Institute for Musculoskeletal Science and Education, Ltd. Implant with a diagonal insertion axis
US10449051B2 (en) 2015-04-29 2019-10-22 Institute for Musculoskeletal Science and Education, Ltd. Implant with curved bone contacting elements
CN104857563A (zh) * 2015-05-25 2015-08-26 苏州奥芮济医疗科技有限公司 一种含Ag氟羟基磷灰石涂层及其制备方法和应用
US11331191B2 (en) 2015-08-12 2022-05-17 Howmedica Osteonics Corp. Bioactive soft tissue implant and methods of manufacture and use thereof
CA2938576A1 (en) 2015-08-12 2017-02-12 Howmedica Osteonics Corp. Methods for forming scaffolds
CN105496609B (zh) * 2015-12-17 2017-12-01 北京市春立正达医疗器械股份有限公司 一种翻修钛网
EP4356938A3 (de) 2016-05-02 2024-07-24 Howmedica Osteonics Corp. Bioaktives weichgewebeimplantat und verfahren zur herstellung und verwendung davon
US20190134276A1 (en) * 2016-06-23 2019-05-09 Drexel University Three dimensional porous cartilage template
DE102017012338B3 (de) * 2016-09-06 2021-04-01 Mathys Ag Bettlach Endoprothesenvorrichtung aus Keramik zum Einsetzen in eine Mulde eines Knochens
US10478312B2 (en) 2016-10-25 2019-11-19 Institute for Musculoskeletal Science and Education, Ltd. Implant with protected fusion zones
US11033394B2 (en) 2016-10-25 2021-06-15 Institute for Musculoskeletal Science and Education, Ltd. Implant with multi-layer bone interfacing lattice
WO2018140967A1 (en) * 2017-01-30 2018-08-02 Slendine Ag Matrix materials having mechanically-shaped sponge architecture and methods of preparing thereof
US10512549B2 (en) 2017-03-13 2019-12-24 Institute for Musculoskeletal Science and Education, Ltd. Implant with structural members arranged around a ring
JP7521152B2 (ja) 2017-09-08 2024-07-24 エクスタント メディカル ホールディングス，インコーポレイテッド． 椎間インプラント、器具、及び方法
USD907771S1 (en) 2017-10-09 2021-01-12 Pioneer Surgical Technology, Inc. Intervertebral implant
CN107899069A (zh) * 2017-11-13 2018-04-13 常州美帛纺织品有限公司 一种医用胶原蛋白复合多孔支架的制备方法
US10744001B2 (en) 2017-11-21 2020-08-18 Institute for Musculoskeletal Science and Education, Ltd. Implant with improved bone contact
US10940015B2 (en) 2017-11-21 2021-03-09 Institute for Musculoskeletal Science and Education, Ltd. Implant with improved flow characteristics
CN108404216B (zh) * 2018-06-08 2020-10-13 中国科学院上海硅酸盐研究所 一种梯度复合材料及其制备方法和应用
US11078334B1 (en) 2018-11-07 2021-08-03 United States of Americas as represented by the Secretary of the Air Force Ceramic nanostructures and process for making same
US11499015B1 (en) 2019-01-15 2022-11-15 United States Of America As Represented By The Secretary Of The Air Force Macromolecular networks and process for making same
WO2020205913A1 (en) * 2019-04-03 2020-10-08 University Of Central Florida Research Foundation, Inc. Frozen, porous thin films and methods of making and use thereof
CN110368529B (zh) * 2019-08-19 2021-08-31 江苏地韵医疗科技有限公司 软骨或软骨下骨全层修复支架及其制备方法
CN111035812A (zh) * 2019-12-20 2020-04-21 厦门大学附属中山医院 一种人源性细胞生物复合补片
US12129211B2 (en) 2021-03-29 2024-10-29 United States Of America As Represented By The Secretary Of The Air Force Extruded ceramic nanofibers and derived materials
CN114886623B (zh) * 2022-06-02 2024-12-27 奥精医疗科技股份有限公司 一种椎间融合器的制备方法
CN115105640B (zh) * 2022-06-20 2023-06-02 四川大学 一种可以骨性愈合连接的隆鼻植入体及其制备方法
CN115634311B (zh) * 2022-09-27 2024-07-02 润原生物科技(苏州)有限公司 一种多结构软骨修复植入物及其制备方法
CN115634317B (zh) * 2022-10-20 2023-09-08 上海市第六人民医院 一种用于神经损伤修复的胶原纤维复合膜

Family Cites Families (59)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3929971A (en) * 1973-03-30 1975-12-30 Research Corp Porous biomaterials and method of making same
US4057537A (en) * 1975-01-28 1977-11-08 Gulf Oil Corporation Copolymers of L-(-)-lactide and epsilon caprolactone
US4045418A (en) * 1975-01-28 1977-08-30 Gulf Oil Corporation Copolymers of D,L-lactide and epsilon caprolactone
US4186448A (en) * 1976-04-16 1980-02-05 Brekke John H Device and method for treating and healing a newly created bone void
US4208511A (en) * 1977-01-19 1980-06-17 Ethicon, Inc. Isomorphic copolyoxalates and sutures thereof
US4141087A (en) * 1977-01-19 1979-02-27 Ethicon, Inc. Isomorphic copolyoxalates and sutures thereof
US4105034A (en) * 1977-06-10 1978-08-08 Ethicon, Inc. Poly(alkylene oxalate) absorbable coating for sutures
US4205399A (en) * 1977-06-13 1980-06-03 Ethicon, Inc. Synthetic absorbable surgical devices of poly(alkylene oxalates)
US4140678A (en) * 1977-06-13 1979-02-20 Ethicon, Inc. Synthetic absorbable surgical devices of poly(alkylene oxalates)
US4130639A (en) * 1977-09-28 1978-12-19 Ethicon, Inc. Absorbable pharmaceutical compositions based on isomorphic copolyoxalates
US4479271A (en) * 1981-10-26 1984-10-30 Zimmer, Inc. Prosthetic device adapted to promote bone/tissue ingrowth
EP0164483B1 (de) * 1984-06-12 1989-08-16 Oscobal Ag Verfahren zur Herstellung von Knochenersatzmaterial
US5133755A (en) * 1986-01-28 1992-07-28 Thm Biomedical, Inc. Method and apparatus for diodegradable, osteogenic, bone graft substitute device
FI80605C (fi) * 1986-11-03 1990-07-10 Biocon Oy Benkirurgisk biokompositmaterial.
CA1340581C (en) * 1986-11-20 1999-06-08 Joseph P. Vacanti Chimeric neomorphogenesis of organs by controlled cellular implantation using artificial matrices
DE3644588C1 (de) 1986-12-27 1988-03-10 Ethicon Gmbh Implantat und Verfahren zu seiner Herstellung
US4861733A (en) * 1987-02-13 1989-08-29 Interpore International Calcium phosphate bone substitute materials
US5306311A (en) * 1987-07-20 1994-04-26 Regen Corporation Prosthetic articular cartilage
GB2215209B (en) * 1988-03-14 1992-08-26 Osmed Inc Method and apparatus for biodegradable, osteogenic, bone graft substitute device
US5108755A (en) * 1989-04-27 1992-04-28 Sri International Biodegradable composites for internal medical use
GB8928250D0 (en) 1989-12-14 1990-02-21 Erba Carlo Spa Use of supercritical fluids to obtain porous sponges of biodegradable polymers
US5486359A (en) * 1990-11-16 1996-01-23 Osiris Therapeutics, Inc. Human mesenchymal stem cells
JP3007903B2 (ja) * 1991-03-29 2000-02-14 京セラ株式会社 人工椎間板
CA2117379C (en) * 1992-02-14 1999-11-16 Kypriacos A. Athanasiou Multi-phase bioerodible implant/carrier and method of manufacturing and using same
US5468253A (en) * 1993-01-21 1995-11-21 Ethicon, Inc. Elastomeric medical device
US5514378A (en) * 1993-02-01 1996-05-07 Massachusetts Institute Of Technology Biocompatible polymer membranes and methods of preparation of three dimensional membrane structures
US5456917A (en) * 1993-04-12 1995-10-10 Cambridge Scientific, Inc. Method for making a bioerodible material for the sustained release of a medicament and the material made from the method
US5522895A (en) * 1993-07-23 1996-06-04 Rice University Biodegradable bone templates
AU7564494A (en) * 1993-08-13 1995-03-14 Smith & Nephew Richards Inc. Microporous polymeric foams and microtextured surfaces
CA2149900C (en) * 1993-09-24 2003-06-24 Yasuo Shikinami Implant material
US5686091A (en) * 1994-03-28 1997-11-11 The Johns Hopkins University School Of Medicine Biodegradable foams for cell transplantation
US5769899A (en) * 1994-08-12 1998-06-23 Matrix Biotechnologies, Inc. Cartilage repair unit
US6376573B1 (en) * 1994-12-21 2002-04-23 Interpore International Porous biomaterials and methods for their manufacture
US5713374A (en) * 1995-02-10 1998-02-03 The Hospital For Joint Diseases Orthopaedic Institute Fixation method for the attachment of wound repair materials to cartilage defects
US5859150A (en) * 1995-03-06 1999-01-12 Ethicon, Inc. Prepolymers of absorbable polyoxaesters
US5607687A (en) * 1995-03-06 1997-03-04 Ethicon, Inc. Polymer blends containing absorbable polyoxaesters
US5595751A (en) * 1995-03-06 1997-01-21 Ethicon, Inc. Absorbable polyoxaesters containing amines and/or amido groups
US5700583A (en) * 1995-03-06 1997-12-23 Ethicon, Inc. Hydrogels of absorbable polyoxaesters containing amines or amido groups
US5618552A (en) * 1995-03-06 1997-04-08 Ethicon, Inc. Absorbable polyoxaesters
US5597579A (en) * 1995-03-06 1997-01-28 Ethicon, Inc. Blends of absorbable polyoxaamides
US5648088A (en) * 1995-03-06 1997-07-15 Ethicon, Inc. Blends of absorbable polyoxaesters containing amines and/or amide groups
US5464929A (en) * 1995-03-06 1995-11-07 Ethicon, Inc. Absorbable polyoxaesters
US5698213A (en) * 1995-03-06 1997-12-16 Ethicon, Inc. Hydrogels of absorbable polyoxaesters
US5716413A (en) * 1995-10-11 1998-02-10 Osteobiologics, Inc. Moldable, hand-shapable biodegradable implant material
GB9522478D0 (en) * 1995-11-02 1996-01-03 Howmedica Prosthetic bearing element and implant incorporating such an element
US5723508A (en) * 1996-01-25 1998-03-03 Northwestern University Method of fabricating emulsion freeze-dried scaffold bodies and resulting products
US5948829A (en) * 1997-11-25 1999-09-07 Kimberly-Clark Worldwide, Inc. Process for preparing an absorbent foam
US5984927A (en) * 1998-03-03 1999-11-16 Ethicon, Inc. Device for sutureless attachment of soft tissue to bone
US6171610B1 (en) * 1998-04-24 2001-01-09 University Of Massachusetts Guided development and support of hydrogel-cell compositions
DE19830752C2 (de) * 1998-07-09 2003-10-16 Itw Ateco Gmbh Befestigungsclip
US6355066B1 (en) * 1998-08-19 2002-03-12 Andrew C. Kim Anterior cruciate ligament reconstruction hamstring tendon fixation system
EP1027897B1 (de) * 1999-02-10 2005-04-13 IsoTis N.V. Verfahren zur Knorpelgeweberegeneration
US6103255A (en) * 1999-04-16 2000-08-15 Rutgers, The State University Porous polymer scaffolds for tissue engineering
US6251143B1 (en) * 1999-06-04 2001-06-26 Depuy Orthopaedics, Inc. Cartilage repair unit
US6306424B1 (en) * 1999-06-30 2001-10-23 Ethicon, Inc. Foam composite for the repair or regeneration of tissue
AU782297B2 (en) * 1999-06-30 2005-07-14 Ethicon Inc. Porous tissue scaffoldings for the repair or regeneration of tissue
US6333029B1 (en) * 1999-06-30 2001-12-25 Ethicon, Inc. Porous tissue scaffoldings for the repair of regeneration of tissue
US6371958B1 (en) * 2000-03-02 2002-04-16 Ethicon, Inc. Scaffold fixation device for use in articular cartilage repair
US6626950B2 (en) * 2001-06-28 2003-09-30 Ethicon, Inc. Composite scaffold with post anchor for the repair and regeneration of tissue

Also Published As

Publication number Publication date
DK1270025T3 (da) 2006-09-11
EP1270025A2 (de) 2003-01-02
DE60211251T2 (de) 2007-03-08
CA2391464A1 (en) 2002-12-27
EP1604696A1 (de) 2005-12-14
AU784287B2 (en) 2006-03-02
JP2003126237A (ja) 2003-05-07
PT1270025E (pt) 2006-08-31
DE60211251D1 (de) 2006-06-14
ES2262759T3 (es) 2006-12-01
EP1270025A3 (de) 2003-03-26
AU4894602A (en) 2003-01-02
US20030003127A1 (en) 2003-01-02
EP1270025B1 (de) 2006-05-10

Similar Documents

Publication Publication Date Title
ATE325629T1 (de) Poröses keramisches/poröses mehrschichtiges polymergerüst zur reparatur und regeneration von gewebe
WO2004062697A3 (en) Silk fibroin materials and use thereof
Toosi et al. PGA‐incorporated collagen: Toward a biodegradable composite scaffold for bone‐tissue engineering
Baheiraei et al. Development of a bioactive porous collagen/β‐tricalcium phosphate bone graft assisting rapid vascularization for bone tissue engineering applications
Hayashi et al. Carbonate apatite micro‐honeycombed blocks generate bone marrow‐like tissues as well as bone
DE60203219D1 (de) Zusammengesetzte Gerüstmatrix mit Stiftanker zur Reparatur und Wiederherstellung von Gewebe
Lv et al. Enhanced angiogenesis and osteogenesis in critical bone defects by the controlled release of BMP-2 and VEGF: implantation of electron beam melting-fabricated porous Ti6Al4V scaffolds incorporating growth factor-doped fibrin glue
Chen et al. Preparation of a biphasic scaffold for osteochondral tissue engineering
US8318902B2 (en) Biomaterial
Jabbarzadeh et al. VEGF‐incorporated biomimetic poly (lactide‐co‐glycolide) sintered microsphere scaffolds for bone tissue engineering
ATE454910T1 (de) Zusammengesetzte strukturen mit hyaluronsäure und derivaten davon als neue knochensubstitute und transplantate
TW369414B (en) Bone formation transplant
Kim et al. In vitro osteogenic differentiation of human amniotic fluid-derived stem cells on a poly (lactide-co-glycolide)(PLGA)–bladder submucosa matrix (BSM) composite scaffold for bone tissue engineering
CN110772668B (zh) 一种软硬组织一体化再生修复梯度三维纤维支架及其制备方法
DE60329514D1 (de) Biologische modulare tibiateil- und femurteilklötze zur verwendung bei totaler kniegelenkrekonstruktion
Rautray et al. Fabrication of strontium–hydroxyapatite scaffolds for biomedical applications
CN101417151A (zh) 生物源性含钙化层骨软骨组织工程支架
WO2009029853A3 (en) Composite scaffold structure
US9259445B2 (en) Integrated implant system (IIS) biocompatible, biodegradable and bioactive, comprising a biocompatible sterile porous polymeric matrix and a gel, integrating in situ the tridimensional matrix structure
Primorac et al. Tissue engineering and future directions in regenerative medicine for knee cartilage repair: a comprehensive review
ATE510805T1 (de) Verfahren zur herstellung von porösen kalziumphosphat granulaten
Hirata et al. Acceleration of bone formation with BMP2 in frame-reinforced carbonate apatite–collagen sponge scaffolds
Chang et al. Fabrication of vascularized bone grafts of predetermined shape with hydroxyapatite-collagen gel beads and autogenous mesenchymal stem cell composites
KR101273204B1 (ko) 골형성 조성물 제조방법
Cho et al. Growth and osteoblastic differentiation of mesenchymal stem cells on silk scaffolds

Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification

Ref document number: 1270025

Country of ref document: EP

REN Ceased due to non-payment of the annual fee