ATE325809T1 - Amidderivate der 2-amino-3-hydroxy-4-tert-leucyl- amino-5-phenyl-pentansäure - Google Patents

Amidderivate der 2-amino-3-hydroxy-4-tert-leucyl- amino-5-phenyl-pentansäure

Info

Publication number
ATE325809T1
ATE325809T1 AT01943442T AT01943442T ATE325809T1 AT E325809 T1 ATE325809 T1 AT E325809T1 AT 01943442 T AT01943442 T AT 01943442T AT 01943442 T AT01943442 T AT 01943442T AT E325809 T1 ATE325809 T1 AT E325809T1
Authority
AT
Austria
Prior art keywords
amino
pentoric
leucyl
tert
hydroxy
Prior art date
Application number
AT01943442T
Other languages
English (en)
Inventor
Pascal Furet
Carlos Garcia-Echeverria
Patricia Imbach
Marc Lang
Johann Zimmermann
Original Assignee
Novartis Pharma Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novartis Pharma Gmbh filed Critical Novartis Pharma Gmbh
Application granted granted Critical
Publication of ATE325809T1 publication Critical patent/ATE325809T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/02—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
    • C07K5/0215—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing natural amino acids, forming a peptide bond via their side chain functional group, e.g. epsilon-Lys, gamma-Glu
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/06—Antipsoriatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Dermatology (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AT01943442T 2000-05-25 2001-05-23 Amidderivate der 2-amino-3-hydroxy-4-tert-leucyl- amino-5-phenyl-pentansäure ATE325809T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB0012795.1A GB0012795D0 (en) 2000-05-25 2000-05-25 Organic compounds

Publications (1)

Publication Number Publication Date
ATE325809T1 true ATE325809T1 (de) 2006-06-15

Family

ID=9892401

Family Applications (1)

Application Number Title Priority Date Filing Date
AT01943442T ATE325809T1 (de) 2000-05-25 2001-05-23 Amidderivate der 2-amino-3-hydroxy-4-tert-leucyl- amino-5-phenyl-pentansäure

Country Status (11)

Country Link
US (2) US20030166572A1 (de)
EP (1) EP1290012B1 (de)
JP (1) JP2003533541A (de)
AT (1) ATE325809T1 (de)
AU (1) AU2001266019A1 (de)
CA (1) CA2405871A1 (de)
DE (1) DE60119514T2 (de)
ES (1) ES2261422T3 (de)
GB (1) GB0012795D0 (de)
PT (1) PT1290012E (de)
WO (1) WO2001089282A2 (de)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2006508166A (ja) * 2002-11-27 2006-03-09 イーラン ファーマスーティカルズ、インコーポレイテッド 置換尿素及びカルバメート
GB0504950D0 (en) * 2005-03-10 2005-04-20 Novartis Ag Organic compositions
CA2604133C (en) 2005-04-07 2015-12-01 Centre National De La Recherche Scientifique Compounds useful as modulators of the proteasome activity
EP2257281A2 (de) * 2008-02-28 2010-12-08 Novartis AG Kombination mit einer cannabinoidrezeptor-bindenden verbindung und einem opioid
WO2010096574A1 (en) 2009-02-20 2010-08-26 Lisanti Michael P A method of diagnosis or prognosis of a neoplasm comprising determining the level of expression of a protein in stromal cells adjacent to the neoplasm
US10085987B2 (en) 2012-01-27 2018-10-02 Thomas Jefferson University MCT protein inhibitor-related prognostic and therapeutic methods
EP2986290A4 (de) 2013-04-19 2017-01-04 Thomas Jefferson University Caveolin-1-verwandte verfahren zur behandlung von glioblastom mit temozolomid
CN118373875A (zh) * 2018-05-29 2024-07-23 奥默罗斯公司 Masp-2抑制剂和使用方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5538997A (en) * 1993-03-12 1996-07-23 Sandoz Ltd. 2,4-diamino-3-hydroxycarboxylic acid derivatives
EP0982317A1 (de) * 1998-08-26 2000-03-01 Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. Bivalente Proteasome Inhibitore
EP1173413B1 (de) * 1999-04-27 2004-06-30 Novartis AG 2,4-diamino-3-hydroxycarboxylsäurederivate als proteasome inhibitoren

Also Published As

Publication number Publication date
CA2405871A1 (en) 2001-11-29
EP1290012B1 (de) 2006-05-10
US20030166572A1 (en) 2003-09-04
PT1290012E (pt) 2006-09-29
DE60119514D1 (de) 2006-06-14
DE60119514T2 (de) 2006-10-05
AU2001266019A1 (en) 2001-12-03
US20060205673A1 (en) 2006-09-14
EP1290012A2 (de) 2003-03-12
WO2001089282A2 (en) 2001-11-29
ES2261422T3 (es) 2006-11-16
WO2001089282A3 (en) 2002-05-10
JP2003533541A (ja) 2003-11-11
GB0012795D0 (en) 2000-07-19

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