ATE325816T1 - Regulatorische regionen des gens für den melatonin 1a rezeptor und deren verwendungen - Google Patents
Regulatorische regionen des gens für den melatonin 1a rezeptor und deren verwendungenInfo
- Publication number
- ATE325816T1 ATE325816T1 AT97934202T AT97934202T ATE325816T1 AT E325816 T1 ATE325816 T1 AT E325816T1 AT 97934202 T AT97934202 T AT 97934202T AT 97934202 T AT97934202 T AT 97934202T AT E325816 T1 ATE325816 T1 AT E325816T1
- Authority
- AT
- Austria
- Prior art keywords
- melatonin
- receptor gene
- therapeutics
- humans
- useful
- Prior art date
Links
- YJPIGAIKUZMOQA-UHFFFAOYSA-N Melatonin Natural products COC1=CC=C2N(C(C)=O)C=C(CCN)C2=C1 YJPIGAIKUZMOQA-UHFFFAOYSA-N 0.000 title abstract 3
- DRLFMBDRBRZALE-UHFFFAOYSA-N melatonin Chemical compound COC1=CC=C2NC=C(CCNC(C)=O)C2=C1 DRLFMBDRBRZALE-UHFFFAOYSA-N 0.000 title abstract 3
- 229960003987 melatonin Drugs 0.000 title abstract 3
- 230000001105 regulatory effect Effects 0.000 title 1
- 239000003814 drug Substances 0.000 abstract 2
- 239000003112 inhibitor Substances 0.000 abstract 2
- 208000017164 Chronobiology disease Diseases 0.000 abstract 1
- 108700039691 Genetic Promoter Regions Proteins 0.000 abstract 1
- 241001465754 Metazoa Species 0.000 abstract 1
- 239000012190 activator Substances 0.000 abstract 1
- 238000009395 breeding Methods 0.000 abstract 1
- 230000001488 breeding effect Effects 0.000 abstract 1
- 230000000977 initiatory effect Effects 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 229920001184 polypeptide Polymers 0.000 abstract 1
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 1
- 102000004196 processed proteins & peptides Human genes 0.000 abstract 1
- 108020003175 receptors Proteins 0.000 abstract 1
- 230000001850 reproductive effect Effects 0.000 abstract 1
- 230000033764 rhythmic process Effects 0.000 abstract 1
- 108091006106 transcriptional activators Proteins 0.000 abstract 1
- 230000002103 transcriptional effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/72—Receptors; Cell surface antigens; Cell surface determinants for hormones
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2217/00—Genetically modified animals
- A01K2217/05—Animals comprising random inserted nucleic acids (transgenic)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2830/00—Vector systems having a special element relevant for transcription
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2830/00—Vector systems having a special element relevant for transcription
- C12N2830/80—Vector systems having a special element relevant for transcription from vertebrates
- C12N2830/85—Vector systems having a special element relevant for transcription from vertebrates mammalian
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Genetics & Genomics (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Zoology (AREA)
- Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- General Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Wood Science & Technology (AREA)
- Biotechnology (AREA)
- Biophysics (AREA)
- Cell Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Physics & Mathematics (AREA)
- Endocrinology (AREA)
- Plant Pathology (AREA)
- Immunology (AREA)
- Toxicology (AREA)
- Gastroenterology & Hepatology (AREA)
- Medicinal Chemistry (AREA)
- Microbiology (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Peptides Or Proteins (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Saccharide Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US2218596P | 1996-07-18 | 1996-07-18 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE325816T1 true ATE325816T1 (de) | 2006-06-15 |
Family
ID=21808259
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT97934202T ATE325816T1 (de) | 1996-07-18 | 1997-07-17 | Regulatorische regionen des gens für den melatonin 1a rezeptor und deren verwendungen |
Country Status (8)
| Country | Link |
|---|---|
| US (2) | US5889177A (de) |
| EP (1) | EP0960129B1 (de) |
| JP (1) | JP2000515018A (de) |
| AT (1) | ATE325816T1 (de) |
| AU (1) | AU729532B2 (de) |
| CA (1) | CA2260763A1 (de) |
| DE (1) | DE69735852D1 (de) |
| WO (1) | WO1998003549A1 (de) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2795427B1 (fr) * | 1999-06-28 | 2001-09-14 | Agronomique Inst Nat Rech | Methode de typage d'un animal photoperiodique pour une fonction physiologique saisonniere comme son aptitude a la reproduction a contre-saison |
| US7223533B2 (en) * | 1999-09-10 | 2007-05-29 | Cadus Technologies, Inc. | Cell surface proteins and use thereof as indicators of activation of cellular signal transduction pathways |
| WO2001079539A2 (de) * | 2000-04-18 | 2001-10-25 | Ipf Pharmaceuticals Gmbh | Verfahren zur anwendung von transfiziebaren konstruktionen aus luziferase und dem promotor des menschlichen period1-gens zur identifizierung neuer wirkstoffe die den tag/nacht-rhythmus und den schlaf beeinflussen |
| CA2373854A1 (en) * | 2002-02-28 | 2003-08-28 | Alain Moreau | Methods of diagnosing and counteracting adolescent idiopathic scoliosis |
| MXPA06003380A (es) * | 2003-09-26 | 2006-06-08 | Pfizer Prod Inc | Uso de antagonista del receptor npy y5 para el tratamiento de trastornos del ritmo circadiano. |
| WO2005030210A1 (en) * | 2003-09-26 | 2005-04-07 | Pfizer Products Inc. | Treatment of neurological disorders related to rapid eye movement (rem) sleep disturbances with npy y5 receptor antagonists |
| CN114525350B (zh) * | 2022-04-22 | 2022-09-16 | 三亚中国农业大学研究院 | 与湖羊的褪黑素性状相关的snp标记及其应用 |
| CN119708184A (zh) * | 2024-12-26 | 2025-03-28 | 山东省农业科学院 | 一种与植物褪黑素合成酶基因comt1的启动子互作的转录因子gata3及其应用 |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5856124A (en) * | 1994-06-17 | 1999-01-05 | The General Hospital Corporation | DNA encoding high-affinity melatonin receptors |
| FR2737220B1 (fr) * | 1995-07-24 | 1997-09-26 | Adir | Sequences nucleiques codant pour des recepteurs de la melatonine et leurs applications |
-
1997
- 1997-07-17 WO PCT/US1997/012526 patent/WO1998003549A1/en not_active Ceased
- 1997-07-17 EP EP97934202A patent/EP0960129B1/de not_active Expired - Lifetime
- 1997-07-17 AU AU37316/97A patent/AU729532B2/en not_active Ceased
- 1997-07-17 AT AT97934202T patent/ATE325816T1/de not_active IP Right Cessation
- 1997-07-17 JP JP10507089A patent/JP2000515018A/ja active Pending
- 1997-07-17 CA CA002260763A patent/CA2260763A1/en not_active Abandoned
- 1997-07-17 US US08/895,701 patent/US5889177A/en not_active Expired - Fee Related
- 1997-07-17 DE DE69735852T patent/DE69735852D1/de not_active Expired - Lifetime
-
1999
- 1999-03-29 US US09/280,420 patent/US6037131A/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| JP2000515018A (ja) | 2000-11-14 |
| US6037131A (en) | 2000-03-14 |
| DE69735852D1 (de) | 2006-06-14 |
| AU729532B2 (en) | 2001-02-01 |
| AU3731697A (en) | 1998-02-10 |
| WO1998003549A1 (en) | 1998-01-29 |
| EP0960129A1 (de) | 1999-12-01 |
| CA2260763A1 (en) | 1998-01-29 |
| EP0960129B1 (de) | 2006-05-10 |
| US5889177A (en) | 1999-03-30 |
| EP0960129A4 (de) | 2001-09-12 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |