ATE325816T1 - Regulatorische regionen des gens für den melatonin 1a rezeptor und deren verwendungen - Google Patents

Regulatorische regionen des gens für den melatonin 1a rezeptor und deren verwendungen

Info

Publication number
ATE325816T1
ATE325816T1 AT97934202T AT97934202T ATE325816T1 AT E325816 T1 ATE325816 T1 AT E325816T1 AT 97934202 T AT97934202 T AT 97934202T AT 97934202 T AT97934202 T AT 97934202T AT E325816 T1 ATE325816 T1 AT E325816T1
Authority
AT
Austria
Prior art keywords
melatonin
receptor gene
therapeutics
humans
useful
Prior art date
Application number
AT97934202T
Other languages
English (en)
Inventor
Steven M Reppert
Original Assignee
Gen Hospital Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Gen Hospital Corp filed Critical Gen Hospital Corp
Application granted granted Critical
Publication of ATE325816T1 publication Critical patent/ATE325816T1/de

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Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/72Receptors; Cell surface antigens; Cell surface determinants for hormones
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01KANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2217/00Genetically modified animals
    • A01K2217/05Animals comprising random inserted nucleic acids (transgenic)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2830/00Vector systems having a special element relevant for transcription
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2830/00Vector systems having a special element relevant for transcription
    • C12N2830/80Vector systems having a special element relevant for transcription from vertebrates
    • C12N2830/85Vector systems having a special element relevant for transcription from vertebrates mammalian

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • General Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Cell Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Physics & Mathematics (AREA)
  • Endocrinology (AREA)
  • Plant Pathology (AREA)
  • Immunology (AREA)
  • Toxicology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Medicinal Chemistry (AREA)
  • Microbiology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Saccharide Compounds (AREA)
AT97934202T 1996-07-18 1997-07-17 Regulatorische regionen des gens für den melatonin 1a rezeptor und deren verwendungen ATE325816T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US2218596P 1996-07-18 1996-07-18

Publications (1)

Publication Number Publication Date
ATE325816T1 true ATE325816T1 (de) 2006-06-15

Family

ID=21808259

Family Applications (1)

Application Number Title Priority Date Filing Date
AT97934202T ATE325816T1 (de) 1996-07-18 1997-07-17 Regulatorische regionen des gens für den melatonin 1a rezeptor und deren verwendungen

Country Status (8)

Country Link
US (2) US5889177A (de)
EP (1) EP0960129B1 (de)
JP (1) JP2000515018A (de)
AT (1) ATE325816T1 (de)
AU (1) AU729532B2 (de)
CA (1) CA2260763A1 (de)
DE (1) DE69735852D1 (de)
WO (1) WO1998003549A1 (de)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2795427B1 (fr) * 1999-06-28 2001-09-14 Agronomique Inst Nat Rech Methode de typage d'un animal photoperiodique pour une fonction physiologique saisonniere comme son aptitude a la reproduction a contre-saison
US7223533B2 (en) * 1999-09-10 2007-05-29 Cadus Technologies, Inc. Cell surface proteins and use thereof as indicators of activation of cellular signal transduction pathways
WO2001079539A2 (de) * 2000-04-18 2001-10-25 Ipf Pharmaceuticals Gmbh Verfahren zur anwendung von transfiziebaren konstruktionen aus luziferase und dem promotor des menschlichen period1-gens zur identifizierung neuer wirkstoffe die den tag/nacht-rhythmus und den schlaf beeinflussen
CA2373854A1 (en) * 2002-02-28 2003-08-28 Alain Moreau Methods of diagnosing and counteracting adolescent idiopathic scoliosis
MXPA06003380A (es) * 2003-09-26 2006-06-08 Pfizer Prod Inc Uso de antagonista del receptor npy y5 para el tratamiento de trastornos del ritmo circadiano.
WO2005030210A1 (en) * 2003-09-26 2005-04-07 Pfizer Products Inc. Treatment of neurological disorders related to rapid eye movement (rem) sleep disturbances with npy y5 receptor antagonists
CN114525350B (zh) * 2022-04-22 2022-09-16 三亚中国农业大学研究院 与湖羊的褪黑素性状相关的snp标记及其应用
CN119708184A (zh) * 2024-12-26 2025-03-28 山东省农业科学院 一种与植物褪黑素合成酶基因comt1的启动子互作的转录因子gata3及其应用

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5856124A (en) * 1994-06-17 1999-01-05 The General Hospital Corporation DNA encoding high-affinity melatonin receptors
FR2737220B1 (fr) * 1995-07-24 1997-09-26 Adir Sequences nucleiques codant pour des recepteurs de la melatonine et leurs applications

Also Published As

Publication number Publication date
JP2000515018A (ja) 2000-11-14
US6037131A (en) 2000-03-14
DE69735852D1 (de) 2006-06-14
AU729532B2 (en) 2001-02-01
AU3731697A (en) 1998-02-10
WO1998003549A1 (en) 1998-01-29
EP0960129A1 (de) 1999-12-01
CA2260763A1 (en) 1998-01-29
EP0960129B1 (de) 2006-05-10
US5889177A (en) 1999-03-30
EP0960129A4 (de) 2001-09-12

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