ATE326457T1 - Indolderivate als 5-ht2c-antagonisten, verfahren zu deren herstellung, sowie diese enthaltende pharmazeutische zusammensetzungen - Google Patents

Indolderivate als 5-ht2c-antagonisten, verfahren zu deren herstellung, sowie diese enthaltende pharmazeutische zusammensetzungen

Info

Publication number: ATE326457T1
Authority: AT; Austria
Prior art keywords: production; pharmaceutical compositions; compositions containing; indole derivatives; ht2c antagonists
Prior art date: 2002-03-27

Application number

AT03290759T

Other languages

English (en)

Inventor

Gilbert Lavielle

Olivier Muller

Mark Millan

Alain Gobert

Original Assignee

Servier Lab

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2002-03-27

Filing date

2003-03-26

Publication date

2006-06-15

2003-03-26 Application filed by Servier Lab filed Critical Servier Lab

2006-06-15 Application granted granted Critical

2006-06-15 Publication of ATE326457T1 publication Critical patent/ATE326457T1/de

Links

102100024959 5-hydroxytryptamine receptor 2C Human genes 0.000 title 1
101710138093 5-hydroxytryptamine receptor 2C Proteins 0.000 title 1
SIKJAQJRHWYJAI-UHFFFAOYSA-N Indole Chemical class C1=CC=C2NC=CC2=C1 SIKJAQJRHWYJAI-UHFFFAOYSA-N 0.000 title 1
239000005557 antagonist Substances 0.000 title 1
229940054051 antipsychotic indole derivative Drugs 0.000 title 1
239000008194 pharmaceutical composition Substances 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/10—Drugs for genital or sexual disorders; Contraceptives for impotence
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/06—Antimigraine agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/26—Psychostimulants, e.g. nicotine, cocaine
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

Health & Medical Sciences (AREA)
Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Chemical Kinetics & Catalysis (AREA)
Animal Behavior & Ethology (AREA)
Medicinal Chemistry (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Biomedical Technology (AREA)
Reproductive Health (AREA)
Psychiatry (AREA)
Endocrinology (AREA)
Diabetes (AREA)
Hematology (AREA)
Obesity (AREA)
Gynecology & Obstetrics (AREA)
Pain & Pain Management (AREA)
Hospice & Palliative Care (AREA)
Psychology (AREA)
Anesthesiology (AREA)
Child & Adolescent Psychology (AREA)
Nutrition Science (AREA)
Pregnancy & Childbirth (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Indole Compounds (AREA)

AT03290759T 2002-03-27 2003-03-26 Indolderivate als 5-ht2c-antagonisten, verfahren zu deren herstellung, sowie diese enthaltende pharmazeutische zusammensetzungen ATE326457T1 (de)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
FR0203788A FR2837823B1 (fr)	2002-03-27	2002-03-27	Nouveaux derives d'indoline, leur procede de preparation et les compositions pharmaceutiques qui les contiennent

Publications (1)

Publication Number	Publication Date
ATE326457T1 true ATE326457T1 (de)	2006-06-15

Family

ID=8871507

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT03290759T ATE326457T1 (de)	2002-03-27	2003-03-26	Indolderivate als 5-ht2c-antagonisten, verfahren zu deren herstellung, sowie diese enthaltende pharmazeutische zusammensetzungen

Country Status (23)

Country	Link
US (2)	US6759421B2 (de)
EP (1)	EP1348704B1 (de)
JP (1)	JP3926284B2 (de)
KR (1)	KR100562207B1 (de)
CN (1)	CN1209359C (de)
AR (1)	AR039145A1 (de)
AT (1)	ATE326457T1 (de)
AU (1)	AU2003203287B2 (de)
BR (1)	BR0300759A (de)
CA (1)	CA2423820C (de)
CY (1)	CY1105509T1 (de)
DE (1)	DE60305229T2 (de)
DK (1)	DK1348704T3 (de)
EA (1)	EA005620B1 (de)
ES (1)	ES2263927T3 (de)
FR (1)	FR2837823B1 (de)
MX (1)	MXPA03002532A (de)
NO (1)	NO324761B1 (de)
NZ (1)	NZ524958A (de)
PL (1)	PL208281B1 (de)
PT (1)	PT1348704E (de)
SI (1)	SI1348704T1 (de)
ZA (1)	ZA200302392B (de)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
KR101005534B1 (ko) *	2008-06-23	2011-01-04	(주)핼릭스케어	충격 흡수력이 우수한 인솔

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
AU4704693A (en) *	1992-08-20	1994-03-15	Smithkline Beecham Plc	Condensed indole derivatives as 5HT-2C and 5HT-2B antagonists
GB9313913D0 (en) *	1993-07-06	1993-08-18	Smithkline Beecham Plc	Novel compounds
JPH09512025A (ja) *	1994-04-23	1997-12-02	スミスクライン・ビーチャム・パブリック・リミテッド・カンパニー	５ｈｔ▲下２ｃ▼および５ｈｔ▲下２ｂ▼アンタゴニストとしての三環式誘導体
US6221884B1 (en) *	1997-06-04	2001-04-24	Eli Lilly And Company	Carboxamides useful as 5-HT1F agonists
FR2807754A1 (fr) *	2000-04-13	2001-10-19	Adir	Nouveaux derives de cyclobuta-indole carboxamide, leur procede de preparation et les compositions pharmaceutiques qui les contiennent

2002
- 2002-03-27 FR FR0203788A patent/FR2837823B1/fr not_active Expired - Fee Related
2003
- 2003-03-24 MX MXPA03002532A patent/MXPA03002532A/es active IP Right Grant
- 2003-03-26 PL PL359357A patent/PL208281B1/pl not_active IP Right Cessation
- 2003-03-26 NO NO20031371A patent/NO324761B1/no not_active IP Right Cessation
- 2003-03-26 DK DK03290759T patent/DK1348704T3/da active
- 2003-03-26 CA CA 2423820 patent/CA2423820C/fr not_active Expired - Fee Related
- 2003-03-26 AR ARP030101050A patent/AR039145A1/es unknown
- 2003-03-26 ES ES03290759T patent/ES2263927T3/es not_active Expired - Lifetime
- 2003-03-26 AT AT03290759T patent/ATE326457T1/de active
- 2003-03-26 EA EA200300302A patent/EA005620B1/ru not_active IP Right Cessation
- 2003-03-26 EP EP03290759A patent/EP1348704B1/de not_active Expired - Lifetime
- 2003-03-26 NZ NZ524958A patent/NZ524958A/en not_active IP Right Cessation
- 2003-03-26 DE DE60305229T patent/DE60305229T2/de not_active Expired - Lifetime
- 2003-03-26 SI SI200330286T patent/SI1348704T1/sl unknown
- 2003-03-26 PT PT03290759T patent/PT1348704E/pt unknown
- 2003-03-26 BR BR0300759-6A patent/BR0300759A/pt not_active IP Right Cessation
- 2003-03-27 ZA ZA200302392A patent/ZA200302392B/xx unknown
- 2003-03-27 KR KR1020030019207A patent/KR100562207B1/ko not_active Expired - Fee Related
- 2003-03-27 CN CNB031211844A patent/CN1209359C/zh not_active Expired - Fee Related
- 2003-03-27 JP JP2003086786A patent/JP3926284B2/ja not_active Expired - Fee Related
- 2003-03-27 AU AU2003203287A patent/AU2003203287B2/en not_active Ceased
- 2003-03-27 US US10/400,358 patent/US6759421B2/en not_active Expired - Fee Related
2004
- 2004-03-30 US US10/813,347 patent/US7053108B2/en not_active Expired - Fee Related
2006
- 2006-07-11 CY CY20061100964T patent/CY1105509T1/el unknown

Also Published As

Publication number	Publication date
US20030199555A1 (en)	2003-10-23
AU2003203287A1 (en)	2003-10-23
CN1209359C (zh)	2005-07-06
JP3926284B2 (ja)	2007-06-06
DK1348704T3 (da)	2006-09-25
FR2837823A1 (fr)	2003-10-03
CY1105509T1 (el)	2010-04-28
US7053108B2 (en)	2006-05-30
ZA200302392B (en)	2003-09-30
US20040192736A1 (en)	2004-09-30
DE60305229D1 (de)	2006-06-22
EA005620B1 (ru)	2005-04-28
EP1348704A1 (de)	2003-10-01
CA2423820C (fr)	2008-08-05
NZ524958A (en)	2004-03-26
MXPA03002532A (es)	2004-09-06
EA200300302A1 (ru)	2003-10-30
KR20030078035A (ko)	2003-10-04
PL208281B1 (pl)	2011-04-29
PT1348704E (pt)	2006-08-31
HK1057368A1 (en)	2004-04-02
JP2004035541A (ja)	2004-02-05
KR100562207B1 (ko)	2006-03-22
BR0300759A (pt)	2004-09-14
SI1348704T1 (sl)	2006-08-31
AR039145A1 (es)	2005-02-09
CA2423820A1 (fr)	2003-09-27
AU2003203287B2 (en)	2008-08-28
NO324761B1 (no)	2007-12-10
ES2263927T3 (es)	2006-12-16
PL359357A1 (en)	2003-10-06
DE60305229T2 (de)	2007-05-24
NO20031371L (no)	2003-09-29
NO20031371D0 (no)	2003-03-26
US6759421B2 (en)	2004-07-06
FR2837823B1 (fr)	2005-04-08
EP1348704B1 (de)	2006-05-17
CN1446813A (zh)	2003-10-08

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