ATE326548T1 - Erkennung von pyrazinamid-resistenten mycobakterien und verfahren zur behandlung von mycobakterien-infektionen - Google Patents

Erkennung von pyrazinamid-resistenten mycobakterien und verfahren zur behandlung von mycobakterien-infektionen

Info

Publication number
ATE326548T1
ATE326548T1 AT97925716T AT97925716T ATE326548T1 AT E326548 T1 ATE326548 T1 AT E326548T1 AT 97925716 T AT97925716 T AT 97925716T AT 97925716 T AT97925716 T AT 97925716T AT E326548 T1 ATE326548 T1 AT E326548T1
Authority
AT
Austria
Prior art keywords
mycobacteria
pyrazinamide
resistant
treating
detection
Prior art date
Application number
AT97925716T
Other languages
English (en)
Inventor
Ying Zhang
Angelo Scorpio
Original Assignee
Univ Johns Hopkins
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Johns Hopkins filed Critical Univ Johns Hopkins
Application granted granted Critical
Publication of ATE326548T1 publication Critical patent/ATE326548T1/de

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Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6888Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms
    • C12Q1/689Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms for bacteria
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14Hydrolases (3)
    • C12N9/78Hydrolases (3) acting on carbon to nitrogen bonds other than peptide bonds (3.5)
    • C12N9/80Hydrolases (3) acting on carbon to nitrogen bonds other than peptide bonds (3.5) acting on amide bonds in linear amides (3.5.1)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/156Polymorphic or mutational markers

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Analytical Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Immunology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Biomedical Technology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AT97925716T 1996-05-31 1997-05-23 Erkennung von pyrazinamid-resistenten mycobakterien und verfahren zur behandlung von mycobakterien-infektionen ATE326548T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US08/655,821 US5846718A (en) 1996-05-31 1996-05-31 Identification of pyrazinamide-resistant mycobacteria and methods for treating mycobacterial infections

Publications (1)

Publication Number Publication Date
ATE326548T1 true ATE326548T1 (de) 2006-06-15

Family

ID=24630514

Family Applications (1)

Application Number Title Priority Date Filing Date
AT97925716T ATE326548T1 (de) 1996-05-31 1997-05-23 Erkennung von pyrazinamid-resistenten mycobakterien und verfahren zur behandlung von mycobakterien-infektionen

Country Status (7)

Country Link
US (1) US5846718A (de)
EP (1) EP0904410B1 (de)
JP (1) JP2000512493A (de)
AT (1) ATE326548T1 (de)
CA (1) CA2254828A1 (de)
DE (1) DE69735885T2 (de)
WO (1) WO1997045558A1 (de)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2000043545A2 (en) * 1999-01-19 2000-07-27 Dade Behring Inc. Detection of drug resistant organisms
US7233953B2 (en) * 2000-12-22 2007-06-19 Siemens Aktiengesellschaft Method for improving functionality of the binary representation of MPEG-7 and of other XML-based contents descriptions
JP4666460B2 (ja) * 2004-12-27 2011-04-06 独立行政法人国立国際医療研究センター ピラジナミド耐性菌検出用プローブセット
CN114525290A (zh) * 2022-01-21 2022-05-24 同济大学 一种PncA优化基因及应用

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0528306B1 (de) * 1991-08-15 1999-11-17 F. Hoffmann-La Roche Ag Primerpaar zum Nachweis von Mycobacterium

Also Published As

Publication number Publication date
EP0904410A4 (de) 2003-04-09
DE69735885D1 (de) 2006-06-22
CA2254828A1 (en) 1997-12-04
EP0904410A1 (de) 1999-03-31
JP2000512493A (ja) 2000-09-26
EP0904410B1 (de) 2006-05-17
WO1997045558A1 (en) 1997-12-04
US5846718A (en) 1998-12-08
DE69735885T2 (de) 2006-11-30

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