ATE329030T1 - Nukleinsäure, welche einen von lektin abstammenden faktor zur präservierung von progenitorzellen kodiert - Google Patents

Nukleinsäure, welche einen von lektin abstammenden faktor zur präservierung von progenitorzellen kodiert

Info

Publication number
ATE329030T1
ATE329030T1 AT98931514T AT98931514T ATE329030T1 AT E329030 T1 ATE329030 T1 AT E329030T1 AT 98931514 T AT98931514 T AT 98931514T AT 98931514 T AT98931514 T AT 98931514T AT E329030 T1 ATE329030 T1 AT E329030T1
Authority
AT
Austria
Prior art keywords
progenitor cells
nucleic acid
vivo
protein
homolog
Prior art date
Application number
AT98931514T
Other languages
English (en)
Inventor
M Gabriella Colucci
Maarten J Chrispeels
Jeffrey G Moore
Original Assignee
Imclone Systems Inc
Univ California
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Imclone Systems Inc, Univ California filed Critical Imclone Systems Inc
Application granted granted Critical
Publication of ATE329030T1 publication Critical patent/ATE329030T1/de

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/87—Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation
    • C12N15/90—Stable introduction of foreign DNA into chromosome
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00—General protective or antinoxious agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/415—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from plants
    • C07K14/42—Lectins, e.g. concanavalin, phytohaemagglutinin
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0634—Cells from the blood or the immune system
    • C12N5/0647—Haematopoietic stem cells; Uncommitted or multipotent progenitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K2035/124—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells the cells being hematopoietic, bone marrow derived or blood cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/20—Cytokines; Chemokines
    • C12N2501/26—Flt-3 ligand (CD135L, flk-2 ligand)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/50—Cell markers; Cell surface determinants
    • C12N2501/59—Lectins

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • Zoology (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Hematology (AREA)
  • Biophysics (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Botany (AREA)
  • Plant Pathology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Immunology (AREA)
  • Mycology (AREA)
  • Cell Biology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Toxicology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
AT98931514T 1997-06-24 1998-06-23 Nukleinsäure, welche einen von lektin abstammenden faktor zur präservierung von progenitorzellen kodiert ATE329030T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US08/881,189 US6310195B1 (en) 1997-06-24 1997-06-24 Nucleic acid encoding a lectin-derived progenitor cell preservation factor

Publications (1)

Publication Number Publication Date
ATE329030T1 true ATE329030T1 (de) 2006-06-15

Family

ID=25377959

Family Applications (1)

Application Number Title Priority Date Filing Date
AT98931514T ATE329030T1 (de) 1997-06-24 1998-06-23 Nukleinsäure, welche einen von lektin abstammenden faktor zur präservierung von progenitorzellen kodiert

Country Status (9)

Country Link
US (4) US6310195B1 (de)
EP (1) EP1017789B1 (de)
JP (1) JP2002507120A (de)
AT (1) ATE329030T1 (de)
AU (1) AU8162698A (de)
CA (1) CA2294195A1 (de)
DE (1) DE69834824T2 (de)
ES (1) ES2265663T3 (de)
WO (1) WO1998059038A1 (de)

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US20020132017A1 (en) * 1996-12-09 2002-09-19 Moore Jeffrey G. Composition and method for preserving progenitor cells
US6310195B1 (en) * 1997-06-24 2001-10-30 Imclone Systems Incorporated Nucleic acid encoding a lectin-derived progenitor cell preservation factor
US6991794B1 (en) 1997-06-24 2006-01-31 Imclone Systems Incorporated Progenitor cell preservation factors and methods for and products of their use
EP1246919B1 (de) * 1999-12-30 2005-08-24 ImClone Systems Incorporated Stammzellen schutzfaktor und verwandte methoden und produkte
EP1584686A1 (de) * 1999-12-30 2005-10-12 ImClone Systems Incorporated Stammzellen Schutzfaktor und verwandte Methoden und Produkte
AU2002248502A1 (en) * 2001-02-27 2002-09-12 Phylogix, Inc. Compositions and methods for protecting tissues and cells from damage, and for repairing damaged tissues
JP2005505261A (ja) * 2001-07-05 2005-02-24 ファイロジックス・インコーポレーテッド 樹状細胞単離法
US7482116B2 (en) 2002-06-07 2009-01-27 Dna Genotek Inc. Compositions and methods for obtaining nucleic acids from sputum
EP1546346A4 (de) * 2002-07-23 2006-02-08 Nanodiagnostics Inc Embryonale stammzellen-marker und verwendungen davon
WO2007116408A2 (en) * 2006-04-11 2007-10-18 Nanodiagnostics Israel Ltd. Pluripotent stem cells characterized by expression of germline specific genes
US8647867B2 (en) 2005-09-30 2014-02-11 National University Corportion Okayama University Cell cultivation method and cell culture
WO2007066352A1 (en) * 2005-12-06 2007-06-14 Department Of Biotechnology A method for preservation of human hematopoietic stem or progenitor cells
WO2007095154A2 (en) * 2006-02-10 2007-08-23 The Brigham And Women's Hospital, Inc. Lectin complement pathway assays and related compositions and methods
AU2008206884B2 (en) * 2007-01-18 2012-07-05 Glykos Finland Oy Novel methods and reagents directed to production of cells
EP2137300B1 (de) 2007-04-26 2011-10-26 Ramot at Tel-Aviv University Ltd. Pluripotente autologe Stammzellen aus der mündlichen oder gastrointestinalen Schleimhaut
EP2315828B1 (de) * 2008-07-11 2015-07-01 Glykos Finland Oy Verfahren zur Kultivierung von induzierten pluripotenten Stammzellen mit einem Lektin
US20100120142A1 (en) 2008-07-11 2010-05-13 Suomen Punainen Risti Veripalvelu Culture of human embryonic cells
US8642007B2 (en) 2010-09-20 2014-02-04 Yanping Kong Method and compound for treatment of cancer using phosphorous-32 labeled DNA
EP2625264B1 (de) 2010-10-08 2022-12-07 Terumo BCT, Inc. Verfahren und systeme für züchtung und ernte von zellen in einem hohlfaser-bioreaktorsystem mit steuerungsbedingungen
KR20140040239A (ko) 2011-06-19 2014-04-02 아보젠, 인크. 샘플 수집을 위한 장치, 용액 및 방법
US9717761B2 (en) 2011-11-21 2017-08-01 Ramot At Tel-Aviv University Ltd. Stem cell-derived neural cells for cell therapy in neurological disorders
EP3068866B1 (de) 2013-11-16 2018-04-25 Terumo BCT, Inc. Zellenexpansion in einem bioreaktor
JP6783143B2 (ja) 2014-03-25 2020-11-11 テルモ ビーシーティー、インコーポレーテッド 培地の受動的補充
CN106715676A (zh) 2014-09-26 2017-05-24 泰尔茂比司特公司 按计划供养
CN107430105A (zh) 2015-02-09 2017-12-01 阿波根有限公司 用于采集相关应用、分析和诊断的样本的设备、溶液和方法
WO2017004592A1 (en) 2015-07-02 2017-01-05 Terumo Bct, Inc. Cell growth with mechanical stimuli
CN109415696A (zh) 2016-05-25 2019-03-01 泰尔茂比司特公司 细胞扩增
US11104874B2 (en) 2016-06-07 2021-08-31 Terumo Bct, Inc. Coating a bioreactor
US11685883B2 (en) 2016-06-07 2023-06-27 Terumo Bct, Inc. Methods and systems for coating a cell growth surface
US11624046B2 (en) 2017-03-31 2023-04-11 Terumo Bct, Inc. Cell expansion
US12234441B2 (en) 2017-03-31 2025-02-25 Terumo Bct, Inc. Cell expansion
US11702634B2 (en) 2017-03-31 2023-07-18 Terumo Bct, Inc. Expanding cells in a bioreactor
US12043823B2 (en) 2021-03-23 2024-07-23 Terumo Bct, Inc. Cell capture and expansion
US12209689B2 (en) 2022-02-28 2025-01-28 Terumo Kabushiki Kaisha Multiple-tube pinch valve assembly
USD1099116S1 (en) 2022-09-01 2025-10-21 Terumo Bct, Inc. Display screen or portion thereof with a graphical user interface for displaying cell culture process steps and measurements of an associated bioreactor device

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JPH0825890B2 (ja) * 1987-06-18 1996-03-13 呉羽化学工業株式会社 抗ウイルス剤
US5053386A (en) * 1987-07-24 1991-10-01 Tung Ta C Orally administrable anti-metastatic lectin compositions and methods
ES2138587T3 (es) * 1990-07-30 2000-01-16 Novartis Ag Proteinas insecticidas.
DE4240635C2 (de) 1992-12-03 1997-07-10 Lothar Prof Dr Kanz Vermehrung hämatopoetischer Vorläuferzellen ex vivo sowieZusammensetzungen hämatopoetischer Wachstumsfaktoren
AU7210394A (en) 1993-06-18 1995-01-17 Trustees Of Princeton University, The Totipotent hematopoietic stem cell receptors and their ligands
US6455678B1 (en) 1996-04-26 2002-09-24 Amcell Corporation Human hematopoietic stem and progenitor cell antigen
US6110891A (en) 1996-06-21 2000-08-29 Alizyme Therapeutics Ltd. Lectin compositions and uses thereof
GB9613070D0 (en) 1996-06-21 1996-08-28 Rowett Research Services Limit Dietary lectins
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US6017527A (en) * 1996-07-10 2000-01-25 Immunex Corporation Activated dendritic cells and methods for their activation
US20020132017A1 (en) * 1996-12-09 2002-09-19 Moore Jeffrey G. Composition and method for preserving progenitor cells
US6084060A (en) * 1996-12-09 2000-07-04 Imclone Systems Incorporated Composition and method for preserving progenitor cells
US6991794B1 (en) * 1997-06-24 2006-01-31 Imclone Systems Incorporated Progenitor cell preservation factors and methods for and products of their use
US6310195B1 (en) * 1997-06-24 2001-10-30 Imclone Systems Incorporated Nucleic acid encoding a lectin-derived progenitor cell preservation factor
EP0922758B1 (de) * 1997-10-27 2009-04-15 Rockefeller University Methode und Zusammensetzung zur Herstellung von reifen dendritischen Zellen

Also Published As

Publication number Publication date
US20070280904A1 (en) 2007-12-06
EP1017789B1 (de) 2006-06-07
DE69834824D1 (de) 2006-07-20
WO1998059038A1 (en) 1998-12-30
US6852321B2 (en) 2005-02-08
EP1017789A4 (de) 2002-01-23
CA2294195A1 (en) 1998-12-30
DE69834824T2 (de) 2006-12-28
US6310195B1 (en) 2001-10-30
US20030049339A1 (en) 2003-03-13
JP2002507120A (ja) 2002-03-05
EP1017789A1 (de) 2000-07-12
ES2265663T3 (es) 2007-02-16
US20050060779A1 (en) 2005-03-17
AU8162698A (en) 1999-01-04

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