ATE329030T1 - Nukleinsäure, welche einen von lektin abstammenden faktor zur präservierung von progenitorzellen kodiert - Google Patents

Nukleinsäure, welche einen von lektin abstammenden faktor zur präservierung von progenitorzellen kodiert

Info

Publication number
ATE329030T1
ATE329030T1 AT98931514T AT98931514T ATE329030T1 AT E329030 T1 ATE329030 T1 AT E329030T1 AT 98931514 T AT98931514 T AT 98931514T AT 98931514 T AT98931514 T AT 98931514T AT E329030 T1 ATE329030 T1 AT E329030T1
Authority
AT
Austria
Prior art keywords
progenitor cells
nucleic acid
vivo
protein
homolog
Prior art date
Application number
AT98931514T
Other languages
English (en)
Inventor
M Gabriella Colucci
Maarten J Chrispeels
Jeffrey G Moore
Original Assignee
Imclone Systems Inc
Univ California
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Imclone Systems Inc, Univ California filed Critical Imclone Systems Inc
Application granted granted Critical
Publication of ATE329030T1 publication Critical patent/ATE329030T1/de

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    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/87Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation
    • C12N15/90Stable introduction of foreign DNA into chromosome
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00General protective or antinoxious agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/415Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from plants
    • C07K14/42Lectins, e.g. concanavalin, phytohaemagglutinin
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06Animal cells or tissues; Human cells or tissues
    • C12N5/0602Vertebrate cells
    • C12N5/0634Cells from the blood or the immune system
    • C12N5/0647Haematopoietic stem cells; Uncommitted or multipotent progenitors
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K2035/124Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells the cells being hematopoietic, bone marrow derived or blood cells
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00Active agents used in cell culture processes, e.g. differentation
    • C12N2501/20Cytokines; Chemokines
    • C12N2501/26Flt-3 ligand (CD135L, flk-2 ligand)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00Active agents used in cell culture processes, e.g. differentation
    • C12N2501/50Cell markers; Cell surface determinants
    • C12N2501/59Lectins

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Hematology (AREA)
  • Microbiology (AREA)
  • Biophysics (AREA)
  • Medicinal Chemistry (AREA)
  • Botany (AREA)
  • Plant Pathology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Physics & Mathematics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Developmental Biology & Embryology (AREA)
  • Mycology (AREA)
  • Immunology (AREA)
  • Cell Biology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Toxicology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
AT98931514T 1997-06-24 1998-06-23 Nukleinsäure, welche einen von lektin abstammenden faktor zur präservierung von progenitorzellen kodiert ATE329030T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US08/881,189 US6310195B1 (en) 1997-06-24 1997-06-24 Nucleic acid encoding a lectin-derived progenitor cell preservation factor

Publications (1)

Publication Number Publication Date
ATE329030T1 true ATE329030T1 (de) 2006-06-15

Family

ID=25377959

Family Applications (1)

Application Number Title Priority Date Filing Date
AT98931514T ATE329030T1 (de) 1997-06-24 1998-06-23 Nukleinsäure, welche einen von lektin abstammenden faktor zur präservierung von progenitorzellen kodiert

Country Status (9)

Country Link
US (4) US6310195B1 (de)
EP (1) EP1017789B1 (de)
JP (1) JP2002507120A (de)
AT (1) ATE329030T1 (de)
AU (1) AU8162698A (de)
CA (1) CA2294195A1 (de)
DE (1) DE69834824T2 (de)
ES (1) ES2265663T3 (de)
WO (1) WO1998059038A1 (de)

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US20020132017A1 (en) * 1996-12-09 2002-09-19 Moore Jeffrey G. Composition and method for preserving progenitor cells
US6991794B1 (en) * 1997-06-24 2006-01-31 Imclone Systems Incorporated Progenitor cell preservation factors and methods for and products of their use
US6310195B1 (en) 1997-06-24 2001-10-30 Imclone Systems Incorporated Nucleic acid encoding a lectin-derived progenitor cell preservation factor
AU784361C (en) * 1999-12-30 2007-03-15 Imclone Systems Incorporated Progenitor cell preservation factors and related methods and products
EP1584686A1 (de) * 1999-12-30 2005-10-12 ImClone Systems Incorporated Stammzellen Schutzfaktor und verwandte Methoden und Produkte
JP2004527495A (ja) * 2001-02-27 2004-09-09 ファイロジックス・エルエルシー 組織および細胞を損傷から保護するための、そして損傷した組織を修復するための、組成物および方法
CA2452691A1 (en) * 2001-07-05 2003-01-16 Phylogix, Inc. Dendritic cell isolation methods
US7482116B2 (en) 2002-06-07 2009-01-27 Dna Genotek Inc. Compositions and methods for obtaining nucleic acids from sputum
WO2007116408A2 (en) * 2006-04-11 2007-10-18 Nanodiagnostics Israel Ltd. Pluripotent stem cells characterized by expression of germline specific genes
CA2493768A1 (en) * 2002-07-23 2004-01-29 Nanodiagnostics, Inc. Embryonic stem cell markers and uses thereof
US8647867B2 (en) 2005-09-30 2014-02-11 National University Corportion Okayama University Cell cultivation method and cell culture
WO2007066352A1 (en) * 2005-12-06 2007-06-14 Department Of Biotechnology A method for preservation of human hematopoietic stem or progenitor cells
WO2007095154A2 (en) * 2006-02-10 2007-08-23 The Brigham And Women's Hospital, Inc. Lectin complement pathway assays and related compositions and methods
EP2108043A4 (de) * 2007-01-18 2010-04-21 Suomen Punainen Risti Veripalv Neue verfahren und reagentien zur produktion von zellen
CN101668848B (zh) 2007-04-26 2014-10-22 雷蒙特亚特特拉维夫大学有限公司 来自口腔粘膜的多能自体干细胞和使用方法
US20100120142A1 (en) * 2008-07-11 2010-05-13 Suomen Punainen Risti Veripalvelu Culture of human embryonic cells
AU2009267964A1 (en) * 2008-07-11 2010-01-14 Glykos Finland Oy Culture of cells
US8642007B2 (en) 2010-09-20 2014-02-04 Yanping Kong Method and compound for treatment of cancer using phosphorous-32 labeled DNA
WO2012048276A2 (en) 2010-10-08 2012-04-12 Caridianbct, Inc. Customizable methods and systems of growing and harvesting cells in a hollow fiber bioreactor system
WO2012177656A2 (en) 2011-06-19 2012-12-27 Abogen, Inc. Devices, solutions and methods for sample collection
WO2013076726A1 (en) 2011-11-21 2013-05-30 Ramot At Tel-Aviv University Ltd. Stem cell-derived neural cells for cell therapy in neurological disorders
WO2015073913A1 (en) 2013-11-16 2015-05-21 Terumo Bct, Inc. Expanding cells in a bioreactor
WO2015148704A1 (en) 2014-03-25 2015-10-01 Terumo Bct, Inc. Passive replacement of media
EP3198006B1 (de) 2014-09-26 2021-03-24 Terumo BCT, Inc. Geplante fütterung
US12038434B2 (en) 2015-02-09 2024-07-16 DNA Genotek, Inc. Devices, solutions and methods for sample collection related applications, analysis and diagnosis
WO2017004592A1 (en) 2015-07-02 2017-01-05 Terumo Bct, Inc. Cell growth with mechanical stimuli
US11965175B2 (en) 2016-05-25 2024-04-23 Terumo Bct, Inc. Cell expansion
US11685883B2 (en) 2016-06-07 2023-06-27 Terumo Bct, Inc. Methods and systems for coating a cell growth surface
US11104874B2 (en) 2016-06-07 2021-08-31 Terumo Bct, Inc. Coating a bioreactor
CN117247899A (zh) 2017-03-31 2023-12-19 泰尔茂比司特公司 细胞扩增
US11624046B2 (en) 2017-03-31 2023-04-11 Terumo Bct, Inc. Cell expansion
US12234441B2 (en) 2017-03-31 2025-02-25 Terumo Bct, Inc. Cell expansion
EP4314244B1 (de) 2021-03-23 2025-07-23 Terumo BCT, Inc. Zellerfassung und -erweiterung
US12209689B2 (en) 2022-02-28 2025-01-28 Terumo Kabushiki Kaisha Multiple-tube pinch valve assembly
USD1099116S1 (en) 2022-09-01 2025-10-21 Terumo Bct, Inc. Display screen or portion thereof with a graphical user interface for displaying cell culture process steps and measurements of an associated bioreactor device

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US5053386A (en) * 1987-07-24 1991-10-01 Tung Ta C Orally administrable anti-metastatic lectin compositions and methods
AU654496B2 (en) * 1990-07-30 1994-11-10 Syngenta Participations Ag Insecticidal proteins
DE4240635C2 (de) 1992-12-03 1997-07-10 Lothar Prof Dr Kanz Vermehrung hämatopoetischer Vorläuferzellen ex vivo sowieZusammensetzungen hämatopoetischer Wachstumsfaktoren
AU7210394A (en) 1993-06-18 1995-01-17 Trustees Of Princeton University, The Totipotent hematopoietic stem cell receptors and their ligands
US6455678B1 (en) 1996-04-26 2002-09-24 Amcell Corporation Human hematopoietic stem and progenitor cell antigen
GB9613070D0 (en) 1996-06-21 1996-08-28 Rowett Research Services Limit Dietary lectins
US6110891A (en) 1996-06-21 2000-08-29 Alizyme Therapeutics Ltd. Lectin compositions and uses thereof
GB9718413D0 (en) 1997-08-29 1997-11-05 Alizyme Therapeutics Ltd Compositions
US6017527A (en) * 1996-07-10 2000-01-25 Immunex Corporation Activated dendritic cells and methods for their activation
US20020132017A1 (en) * 1996-12-09 2002-09-19 Moore Jeffrey G. Composition and method for preserving progenitor cells
US6084060A (en) * 1996-12-09 2000-07-04 Imclone Systems Incorporated Composition and method for preserving progenitor cells
US6991794B1 (en) * 1997-06-24 2006-01-31 Imclone Systems Incorporated Progenitor cell preservation factors and methods for and products of their use
US6310195B1 (en) 1997-06-24 2001-10-30 Imclone Systems Incorporated Nucleic acid encoding a lectin-derived progenitor cell preservation factor
DE69840739D1 (de) * 1997-10-27 2009-05-28 Merix Bioscience Inc Methode und Zusammensetzung zur Herstellung von reifen dendritischen Zellen

Also Published As

Publication number Publication date
WO1998059038A1 (en) 1998-12-30
EP1017789A4 (de) 2002-01-23
DE69834824D1 (de) 2006-07-20
US6852321B2 (en) 2005-02-08
DE69834824T2 (de) 2006-12-28
ES2265663T3 (es) 2007-02-16
US20050060779A1 (en) 2005-03-17
AU8162698A (en) 1999-01-04
US20070280904A1 (en) 2007-12-06
CA2294195A1 (en) 1998-12-30
EP1017789A1 (de) 2000-07-12
EP1017789B1 (de) 2006-06-07
JP2002507120A (ja) 2002-03-05
US6310195B1 (en) 2001-10-30
US20030049339A1 (en) 2003-03-13

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