ATE329030T1 - Nukleinsäure, welche einen von lektin abstammenden faktor zur präservierung von progenitorzellen kodiert - Google Patents

Nukleinsäure, welche einen von lektin abstammenden faktor zur präservierung von progenitorzellen kodiert

Info

Publication number
ATE329030T1
ATE329030T1 AT98931514T AT98931514T ATE329030T1 AT E329030 T1 ATE329030 T1 AT E329030T1 AT 98931514 T AT98931514 T AT 98931514T AT 98931514 T AT98931514 T AT 98931514T AT E329030 T1 ATE329030 T1 AT E329030T1
Authority
AT
Austria
Prior art keywords
progenitor cells
nucleic acid
vivo
protein
homolog
Prior art date
Application number
AT98931514T
Other languages
English (en)
Inventor
M Gabriella Colucci
Maarten J Chrispeels
Jeffrey G Moore
Original Assignee
Imclone Systems Inc
Univ California
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Imclone Systems Inc, Univ California filed Critical Imclone Systems Inc
Application granted granted Critical
Publication of ATE329030T1 publication Critical patent/ATE329030T1/de

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/87—Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation
    • C12N15/90—Stable introduction of foreign DNA into chromosome
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00—General protective or antinoxious agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/415—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from plants
    • C07K14/42—Lectins, e.g. concanavalin, phytohaemagglutinin
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0634—Cells from the blood or the immune system
    • C12N5/0647—Haematopoietic stem cells; Uncommitted or multipotent progenitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K2035/124—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells the cells being hematopoietic, bone marrow derived or blood cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/20—Cytokines; Chemokines
    • C12N2501/26—Flt-3 ligand (CD135L, flk-2 ligand)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/50—Cell markers; Cell surface determinants
    • C12N2501/59—Lectins

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Biophysics (AREA)
  • Microbiology (AREA)
  • Hematology (AREA)
  • Medicinal Chemistry (AREA)
  • Mycology (AREA)
  • Botany (AREA)
  • Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Plant Pathology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Cell Biology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Toxicology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
AT98931514T 1997-06-24 1998-06-23 Nukleinsäure, welche einen von lektin abstammenden faktor zur präservierung von progenitorzellen kodiert ATE329030T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US08/881,189 US6310195B1 (en) 1997-06-24 1997-06-24 Nucleic acid encoding a lectin-derived progenitor cell preservation factor

Publications (1)

Publication Number Publication Date
ATE329030T1 true ATE329030T1 (de) 2006-06-15

Family

ID=25377959

Family Applications (1)

Application Number Title Priority Date Filing Date
AT98931514T ATE329030T1 (de) 1997-06-24 1998-06-23 Nukleinsäure, welche einen von lektin abstammenden faktor zur präservierung von progenitorzellen kodiert

Country Status (9)

Country Link
US (4) US6310195B1 (de)
EP (1) EP1017789B1 (de)
JP (1) JP2002507120A (de)
AT (1) ATE329030T1 (de)
AU (1) AU8162698A (de)
CA (1) CA2294195A1 (de)
DE (1) DE69834824T2 (de)
ES (1) ES2265663T3 (de)
WO (1) WO1998059038A1 (de)

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Publication number Priority date Publication date Assignee Title
US20020132017A1 (en) * 1996-12-09 2002-09-19 Moore Jeffrey G. Composition and method for preserving progenitor cells
US6310195B1 (en) * 1997-06-24 2001-10-30 Imclone Systems Incorporated Nucleic acid encoding a lectin-derived progenitor cell preservation factor
US6991794B1 (en) * 1997-06-24 2006-01-31 Imclone Systems Incorporated Progenitor cell preservation factors and methods for and products of their use
EP1584686A1 (de) * 1999-12-30 2005-10-12 ImClone Systems Incorporated Stammzellen Schutzfaktor und verwandte Methoden und Produkte
ES2249058T3 (es) * 1999-12-30 2006-03-16 Imclone Systems Inc Factores de preservacion de celulas progenitoras y metodos y productos relacionados.
JP2004527495A (ja) * 2001-02-27 2004-09-09 ファイロジックス・エルエルシー 組織および細胞を損傷から保護するための、そして損傷した組織を修復するための、組成物および方法
CA2452691A1 (en) * 2001-07-05 2003-01-16 Phylogix, Inc. Dendritic cell isolation methods
US7482116B2 (en) 2002-06-07 2009-01-27 Dna Genotek Inc. Compositions and methods for obtaining nucleic acids from sputum
WO2004009758A2 (en) * 2002-07-23 2004-01-29 Nanodiagnostics, Inc. Embryonic stem cell markers and uses thereof
WO2007037407A1 (ja) 2005-09-30 2007-04-05 3-D Matrix Japan, Ltd. 細胞の培養方法および細胞培養物
US8859282B2 (en) * 2005-12-06 2014-10-14 Department Of Biotechnology Method for preservation of human hematopoietic stem or progenitor cells
US8524453B2 (en) * 2006-02-10 2013-09-03 The Brigham And Woman's Hospital, Inc. Lectin complement pathway assays and related compositions and methods
US20100297087A1 (en) * 2006-04-11 2010-11-25 Nanodiagnostics Israel., Ltd Pluripotent stem cells characterized by expression of germline specific genes
CA2676323A1 (en) 2007-01-18 2008-07-24 Suomen Punainen Risti, Veripalvelu Novel methods and reagents directed to production of cells
WO2008132722A1 (en) 2007-04-26 2008-11-06 Ramot At Tel-Aviv University Ltd. Pluripotent autologous stem cells from oral mucosa and methods of use
AU2009267964A1 (en) * 2008-07-11 2010-01-14 Glykos Finland Oy Culture of cells
US20100120142A1 (en) 2008-07-11 2010-05-13 Suomen Punainen Risti Veripalvelu Culture of human embryonic cells
US8642007B2 (en) 2010-09-20 2014-02-04 Yanping Kong Method and compound for treatment of cancer using phosphorous-32 labeled DNA
US8895291B2 (en) 2010-10-08 2014-11-25 Terumo Bct, Inc. Methods and systems of growing and harvesting cells in a hollow fiber bioreactor system with control conditions
EP3150702B1 (de) 2011-06-19 2021-05-19 DNA Genotek, Inc. Vorrichtungen, lösungen und verfahren zur probenentnahme
EP2782587B1 (de) 2011-11-21 2018-11-07 Ramot at Tel Aviv University, Ltd. Aus stammzellen gewonnene nervenzellen zur zelltherapie bei neurologischen krankheiten
JP6612227B2 (ja) 2013-11-16 2019-11-27 テルモ ビーシーティー、インコーポレーテッド バイオリアクターにおける細胞増殖
US11008547B2 (en) 2014-03-25 2021-05-18 Terumo Bct, Inc. Passive replacement of media
WO2016049421A1 (en) 2014-09-26 2016-03-31 Terumo Bct, Inc. Scheduled feed
EP3256849A4 (de) 2015-02-09 2018-12-05 Abogen, Inc. Vorrichtungen, lösungen und verfahren für anwendungen im zusammenhang mitprobeentnahme, analyse und diagnose
WO2017004592A1 (en) 2015-07-02 2017-01-05 Terumo Bct, Inc. Cell growth with mechanical stimuli
WO2017205667A1 (en) 2016-05-25 2017-11-30 Terumo Bct, Inc. Cell expansion
US11104874B2 (en) 2016-06-07 2021-08-31 Terumo Bct, Inc. Coating a bioreactor
US11685883B2 (en) 2016-06-07 2023-06-27 Terumo Bct, Inc. Methods and systems for coating a cell growth surface
US11624046B2 (en) 2017-03-31 2023-04-11 Terumo Bct, Inc. Cell expansion
US12234441B2 (en) 2017-03-31 2025-02-25 Terumo Bct, Inc. Cell expansion
WO2018184028A2 (en) 2017-03-31 2018-10-04 Terumo Bct, Inc. Cell expansion
GB2619893A (en) 2021-03-23 2023-12-20 Terumo Bct Inc Cell capture and expansion
US12209689B2 (en) 2022-02-28 2025-01-28 Terumo Kabushiki Kaisha Multiple-tube pinch valve assembly
USD1099116S1 (en) 2022-09-01 2025-10-21 Terumo Bct, Inc. Display screen or portion thereof with a graphical user interface for displaying cell culture process steps and measurements of an associated bioreactor device

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US4808611A (en) 1986-07-30 1989-02-28 Immunex Corporation Use of interleukin-1 to induce development of multipotent hemopoietic cell populations
US5186931A (en) 1986-08-06 1993-02-16 Ajinomoto Co., Inc. Composition and method for supporting bone marrow transplantation
JPH0825890B2 (ja) * 1987-06-18 1996-03-13 呉羽化学工業株式会社 抗ウイルス剤
US5053386A (en) * 1987-07-24 1991-10-01 Tung Ta C Orally administrable anti-metastatic lectin compositions and methods
EP0542833B1 (de) * 1990-07-30 1999-09-01 Novartis AG Insektizide proteine
DE4240635C2 (de) 1992-12-03 1997-07-10 Lothar Prof Dr Kanz Vermehrung hämatopoetischer Vorläuferzellen ex vivo sowieZusammensetzungen hämatopoetischer Wachstumsfaktoren
AU7210394A (en) 1993-06-18 1995-01-17 Trustees Of Princeton University, The Totipotent hematopoietic stem cell receptors and their ligands
US6455678B1 (en) 1996-04-26 2002-09-24 Amcell Corporation Human hematopoietic stem and progenitor cell antigen
GB9718413D0 (en) 1997-08-29 1997-11-05 Alizyme Therapeutics Ltd Compositions
GB9613070D0 (en) 1996-06-21 1996-08-28 Rowett Research Services Limit Dietary lectins
US6110891A (en) 1996-06-21 2000-08-29 Alizyme Therapeutics Ltd. Lectin compositions and uses thereof
US6017527A (en) * 1996-07-10 2000-01-25 Immunex Corporation Activated dendritic cells and methods for their activation
US6084060A (en) 1996-12-09 2000-07-04 Imclone Systems Incorporated Composition and method for preserving progenitor cells
US20020132017A1 (en) * 1996-12-09 2002-09-19 Moore Jeffrey G. Composition and method for preserving progenitor cells
US6991794B1 (en) * 1997-06-24 2006-01-31 Imclone Systems Incorporated Progenitor cell preservation factors and methods for and products of their use
US6310195B1 (en) 1997-06-24 2001-10-30 Imclone Systems Incorporated Nucleic acid encoding a lectin-derived progenitor cell preservation factor
DE69840739D1 (de) * 1997-10-27 2009-05-28 Merix Bioscience Inc Methode und Zusammensetzung zur Herstellung von reifen dendritischen Zellen

Also Published As

Publication number Publication date
EP1017789A1 (de) 2000-07-12
EP1017789A4 (de) 2002-01-23
ES2265663T3 (es) 2007-02-16
US20070280904A1 (en) 2007-12-06
DE69834824T2 (de) 2006-12-28
DE69834824D1 (de) 2006-07-20
US6852321B2 (en) 2005-02-08
WO1998059038A1 (en) 1998-12-30
US6310195B1 (en) 2001-10-30
CA2294195A1 (en) 1998-12-30
US20050060779A1 (en) 2005-03-17
EP1017789B1 (de) 2006-06-07
US20030049339A1 (en) 2003-03-13
AU8162698A (en) 1999-01-04
JP2002507120A (ja) 2002-03-05

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