ATE332364T1 - Verfahren zur gewinnung von purifizierter virenzuammensetzung - Google Patents
Verfahren zur gewinnung von purifizierter virenzuammensetzungInfo
- Publication number
- ATE332364T1 ATE332364T1 AT00906444T AT00906444T ATE332364T1 AT E332364 T1 ATE332364 T1 AT E332364T1 AT 00906444 T AT00906444 T AT 00906444T AT 00906444 T AT00906444 T AT 00906444T AT E332364 T1 ATE332364 T1 AT E332364T1
- Authority
- AT
- Austria
- Prior art keywords
- purified virus
- virus composition
- obtaining purified
- viral
- particles
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 3
- 241000700605 Viruses Species 0.000 title 1
- 230000003612 virological effect Effects 0.000 abstract 3
- 239000002245 particle Substances 0.000 abstract 2
- 238000001415 gene therapy Methods 0.000 abstract 1
- 238000001179 sorption measurement Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/10011—Adenoviridae
- C12N2710/10051—Methods of production or purification of viral material
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Organic Chemistry (AREA)
- Zoology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Wood Science & Technology (AREA)
- Virology (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Biomedical Technology (AREA)
- Medicinal Chemistry (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Immunology (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR9902167 | 1999-02-22 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE332364T1 true ATE332364T1 (de) | 2006-07-15 |
Family
ID=9542357
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT00906444T ATE332364T1 (de) | 1999-02-22 | 2000-02-21 | Verfahren zur gewinnung von purifizierter virenzuammensetzung |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US7264958B1 (de) |
| EP (1) | EP1155120B1 (de) |
| JP (2) | JP4802366B2 (de) |
| AT (1) | ATE332364T1 (de) |
| AU (1) | AU774437B2 (de) |
| CA (1) | CA2364934C (de) |
| DE (1) | DE60029195T2 (de) |
| WO (1) | WO2000050573A1 (de) |
Families Citing this family (64)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IL139040A0 (en) | 1998-04-22 | 2001-11-25 | Genvec Inc | Efficient purification of adenovirus |
| JP5322252B2 (ja) * | 2001-12-20 | 2013-10-23 | バヴァリアン・ノルディック・アクティーゼルスカブ | 感染細胞からのポックスウイルスの採取および精製法 |
| ATE500267T1 (de) | 2003-07-21 | 2011-03-15 | Transgene Sa | Multifunktionelle cytokine |
| US20070207461A1 (en) | 2004-02-23 | 2007-09-06 | Crucell Holland B.V. | Virus Purification Methods |
| CA2602944C (en) | 2005-04-11 | 2015-08-11 | Crucell Holland B.V. | Virus purification using ultrafiltration |
| JP4670583B2 (ja) * | 2005-10-20 | 2011-04-13 | チッソ株式会社 | 水溶性カチオン性磁気微粒子を用いた脂質ベシクルの分離又は検出方法 |
| WO2008008872A2 (en) * | 2006-07-14 | 2008-01-17 | Wisconsin Alumni Research Foundation | Adsorptive membranes for trapping viruses |
| CL2008000249A1 (es) | 2007-01-30 | 2008-05-30 | Transgene Sa | Uso de una molecula de acido nucleico que codifica al menos un polipeptido e2 del papilomavirus, un vector o una particula virica infecciosa que la comprenda para tratar una infeccion permanente por papilomavirus causada por al menos un papilomavirus |
| US10041049B2 (en) | 2008-11-03 | 2018-08-07 | Janssen Vaccines & Prevention B.V. | Method for the production of adenoviral vectors |
| AU2010206195B2 (en) | 2009-01-20 | 2016-03-10 | Transgene Sa | Soluble ICAM-1 as biomarker for prediction of therapeutic response |
| ES2555858T3 (es) | 2009-03-24 | 2016-01-11 | Transgene Sa | Biomarcador para el control de pacientes |
| PL2419728T3 (pl) | 2009-04-17 | 2014-05-30 | Transgene Sa | Biomarker do monitorowania pacjentów |
| CN102483405B (zh) | 2009-07-10 | 2015-12-02 | 特朗斯吉有限公司 | 用于选择患者的生物标志物及相关方法 |
| RU2555346C2 (ru) | 2009-08-07 | 2015-07-10 | Трансген Са | Композиция для лечения инфекции вирусом гепатита в |
| MX2012007936A (es) | 2010-02-15 | 2012-11-22 | Crucell Holland Bv | Metodo para la produccion de vectores adenovirales del serotipo 26 del adenovirus. |
| US10130697B2 (en) | 2010-03-23 | 2018-11-20 | Wisconsin Alumni Research Foundation (Warf) | Vaccines comprising mutant attenuated influenza viruses |
| CA2816190C (en) * | 2010-10-27 | 2020-03-24 | Philip Morris Products S.A. | Methods for capturing virus like particles from plants using expanded bed chromatography |
| CA2819552C (en) | 2010-12-09 | 2023-09-26 | Institut Pasteur | Mgmt-based method for obtaining high yield of recombinant protein expression |
| JP2014527799A (ja) | 2011-08-26 | 2014-10-23 | ダブリュエーアールエフ−ウィスコンシン アラムナイ リサーチ ファウンデーション | 変異型pb2遺伝子セグメントを有する弱毒化生ワクチンとしてのインフルエンザウイルス |
| TW201318637A (zh) | 2011-09-29 | 2013-05-16 | Transgene Sa | 免疫療法組成物及用於治療c型肝炎病毒感染之療程(一) |
| WO2013045668A2 (en) | 2011-09-29 | 2013-04-04 | Transgene Sa | Immunotherapy composition and regimen for treating hepatitis c virus infection |
| WO2014009433A1 (en) | 2012-07-10 | 2014-01-16 | Transgene Sa | Mycobacterium resuscitation promoting factor for use as adjuvant |
| TWI638829B (zh) | 2012-07-10 | 2018-10-21 | 法商傳斯堅公司 | 分枝桿菌抗原疫苗 |
| EP3587455A1 (de) | 2012-10-23 | 2020-01-01 | Emory University | Gm-csf- und il-4-konjugate, zusammensetzungen und zugehörige verfahren |
| CA2914790C (en) | 2013-06-14 | 2024-02-27 | Psioxus Therapeutics Limited | A dosing regime and formulations for type b adenoviruses |
| HUE035875T2 (hu) | 2013-10-25 | 2018-06-28 | Psioxus Therapeutics Ltd | Heterológ géneket tartalmazó onkolitikus adenovírusok |
| WO2015104380A1 (en) | 2014-01-09 | 2015-07-16 | Transgene Sa | Fusion of heterooligomeric mycobacterial antigens |
| US10053671B2 (en) | 2014-06-20 | 2018-08-21 | Wisconsin Alumni Research Foundation (Warf) | Mutations that confer genetic stability to additional genes in influenza viruses |
| EP4523756A3 (de) | 2015-02-13 | 2025-05-28 | Transgene | Immunotherapeutischer impfstoff und antikörperkombinationstherapie |
| WO2016131945A1 (en) | 2015-02-20 | 2016-08-25 | Transgene Sa | Combination product with autophagy modulator |
| BR112018012180A2 (pt) | 2015-12-17 | 2018-12-04 | Psioxus Therapeutics Ltd | vírus de codificação de um anticorpo ou fragmento de complexo anti-tcr |
| US11197925B2 (en) | 2016-02-19 | 2021-12-14 | Wisconsin Alumni Research Foundation (Warf) | Influenza B virus replication for vaccine development |
| CA3023022A1 (en) | 2016-05-04 | 2017-11-09 | Transgene Sa | Combination therapy with cpg tlr9 ligand |
| IL303187A (en) | 2016-08-29 | 2023-07-01 | Akamis Bio Ltd | Adenovirus with bispecific T cell activator |
| GB201713765D0 (en) | 2017-08-28 | 2017-10-11 | Psioxus Therapeutics Ltd | Modified adenovirus |
| WO2018069316A2 (en) | 2016-10-10 | 2018-04-19 | Transgene Sa | Immunotherapeutic product and mdsc modulator combination therapy |
| US11826423B2 (en) | 2016-11-16 | 2023-11-28 | Immunomic Therapeutics, Inc. | Nucleic acids for treatment of allergies |
| IL270024B2 (en) | 2017-04-22 | 2025-04-01 | Immunomic Therapeutics Inc | LAMP structures and their use in vaccination |
| KR20200016224A (ko) | 2017-05-02 | 2020-02-14 | 이뮤노믹 쎄라퓨틱스, 인크. | 암 항원을 포함하는 lamp (리소솜 연관 막 단백질) 구축물 |
| WO2019084310A1 (en) | 2017-10-25 | 2019-05-02 | Yoshihiro Kawaoka | HAS RECOMBINANT INFLUENZA VIRUSES STABILIZED FOR EGG REPLICATION |
| GB201801614D0 (en) | 2018-01-31 | 2018-03-14 | Psioxus Therapeutics Ltd | Formulation |
| EP3793595A1 (de) | 2018-05-15 | 2021-03-24 | Immunomic Therapeutics, Inc. | Verbesserte lamp-konstrukte mit allergenen |
| US12343390B2 (en) | 2018-08-07 | 2025-07-01 | Wisconsin Alumni Research Foundation (Warf) | Recombinant biologically contained filovirus vaccine |
| JP7655849B2 (ja) | 2018-08-20 | 2025-04-02 | ウィスコンシン アルムニ リサーチ ファンデイション | ヘマグルチニン(ha)タンパク質内の非ドミナントエピトープに対する免疫応答を誘起するためのベクター |
| WO2020061528A1 (en) | 2018-09-21 | 2020-03-26 | University Of Connecticut | Compositions and methods to restore paternal ube3a gene expression in human angelman syndrome |
| AU2019382919A1 (en) * | 2018-11-22 | 2021-05-27 | Fixed Phage Limited | Production of immobilised bacteriophage |
| TWI852977B (zh) | 2019-01-10 | 2024-08-21 | 美商健生生物科技公司 | 前列腺新抗原及其用途 |
| EP3921413A1 (de) | 2019-02-08 | 2021-12-15 | Wisconsin Alumni Research Foundation (WARF) | Humanisierte zelllinie |
| CN114929269A (zh) | 2019-05-01 | 2022-08-19 | 威斯康星校友研究基金会(Warf) | 用于疫苗开发的改进的流感病毒复制 |
| GB201909081D0 (en) * | 2019-06-25 | 2019-08-07 | Psioxus Therapeutics Ltd | Method |
| US11807872B2 (en) | 2019-08-27 | 2023-11-07 | Wisconsin Alumni Research Foundation (Warf) | Recombinant influenza viruses with stabilized HA for replication in eggs |
| JP2022551732A (ja) | 2019-10-18 | 2022-12-13 | イミュノミック セラピューティックス, インコーポレイテッド | がん抗原を含む改良lamp構築物 |
| CR20220220A (es) | 2019-11-18 | 2022-09-20 | Janssen Biotech Inc | Vacunas basadas en calr y jak2 mutantes y sus usos |
| JP2023511444A (ja) | 2020-01-24 | 2023-03-17 | ウィスコンシン アルムニ リサーチ ファンデイション | 安定化されたnaを有する組換えインフルエンザウイルス |
| TW202144389A (zh) | 2020-02-14 | 2021-12-01 | 美商健生生物科技公司 | 在多發性骨髓瘤中表現之新抗原及其用途 |
| TW202144388A (zh) | 2020-02-14 | 2021-12-01 | 美商健生生物科技公司 | 在卵巢癌中表現之新抗原及其用途 |
| WO2021195410A1 (en) | 2020-03-25 | 2021-09-30 | Wisconsin Alumni Research Foundation (Warf) | Recombinant multivalent influenza viruses |
| WO2021209897A1 (en) | 2020-04-13 | 2021-10-21 | Janssen Biotech, Inc. | Psma and steap1 vaccines and their uses |
| EP4175664A2 (de) | 2020-07-06 | 2023-05-10 | Janssen Biotech, Inc. | Prostata-neoantigene und ihre verwendungen |
| US20230024133A1 (en) | 2020-07-06 | 2023-01-26 | Janssen Biotech, Inc. | Prostate Neoantigens And Their Uses |
| US20230035403A1 (en) | 2020-07-06 | 2023-02-02 | Janssen Biotech, Inc. | Method For Determining Responsiveness To Prostate Cancer Treatment |
| US20230241530A1 (en) * | 2022-02-01 | 2023-08-03 | W. L. Gore & Associates, Inc. | Affinity chromatography devices containing a heat treated fibrillated polymer membrane for the separation of mrna and viral vectors from an aqueous mixture |
| EP4508071A1 (de) | 2022-04-10 | 2025-02-19 | Immunomic Therapeutics, Inc. | Bicistronische lampenkonstrukte mit immunreaktionserhöhenden genen und verfahren zur verwendung davon |
| WO2025158316A1 (en) | 2024-01-26 | 2025-07-31 | Janssen Biotech, Inc. | Ovarian neoantigens and use thereof |
Family Cites Families (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0328256A1 (de) * | 1988-01-21 | 1989-08-16 | Owens-Corning Fiberglas Corporation | Glasfaser, überzogen mit Agarose, zur Verwendung als Säulenpackung oder chromatographisches Medium in Biotrennungen |
| GB8806605D0 (en) | 1988-03-19 | 1988-04-20 | Robinson E | Composite adsorbents |
| SE9101149D0 (sv) * | 1991-04-17 | 1991-04-17 | Pharmacia Lkb Biotech | Beads for down stream processing |
| DE4128953A1 (de) | 1991-08-30 | 1993-03-04 | Basf Ag | Verfahren zur kultivierung von saeugerzellen im fliessbettreaktor |
| US5837520A (en) * | 1995-03-07 | 1998-11-17 | Canji, Inc. | Method of purification of viral vectors |
| FR2737730B1 (fr) | 1995-08-10 | 1997-09-05 | Pasteur Merieux Serums Vacc | Procede de purification de virus par chromatographie |
| WO1997008298A1 (en) * | 1995-08-30 | 1997-03-06 | Genzyme Corporation | Chromatographic purification of adenovirus and aav |
| AU2660397A (en) * | 1996-04-05 | 1997-10-29 | Board Of Regents, The University Of Texas System | Methods for producing soluble, biologically-active disulfide bond-containing eukaryotic proteins in bacterial cells |
| IL127692A0 (en) | 1996-07-01 | 1999-10-28 | Rhone Poulenc Rorer Sa | Method for producing recombinant adenovirus |
| WO1998022588A2 (en) | 1996-11-20 | 1998-05-28 | Introgen Therapeutics, Inc. | An improved method for the production and purification of adenoviral vectors |
| AU5370598A (en) | 1996-12-13 | 1998-07-03 | Schering Corporation | Methods for purifying viruses |
| SE9700383D0 (sv) * | 1997-02-04 | 1997-02-04 | Pharmacia Biotech Ab | An adsorption/separation method and a medium for adsorption/separation |
| WO1999040702A1 (en) | 1998-02-04 | 1999-08-12 | Sun Microsystems, Inc. | Method and apparatus for efficient authentication and integrity checking using hierarchical hashing |
| IL139040A0 (en) | 1998-04-22 | 2001-11-25 | Genvec Inc | Efficient purification of adenovirus |
-
2000
- 2000-02-21 JP JP2000601137A patent/JP4802366B2/ja not_active Expired - Lifetime
- 2000-02-21 WO PCT/FR2000/000430 patent/WO2000050573A1/fr not_active Ceased
- 2000-02-21 CA CA2364934A patent/CA2364934C/fr not_active Expired - Lifetime
- 2000-02-21 US US09/914,036 patent/US7264958B1/en not_active Expired - Lifetime
- 2000-02-21 EP EP00906444A patent/EP1155120B1/de not_active Expired - Lifetime
- 2000-02-21 AU AU28118/00A patent/AU774437B2/en not_active Expired
- 2000-02-21 DE DE60029195T patent/DE60029195T2/de not_active Expired - Lifetime
- 2000-02-21 AT AT00906444T patent/ATE332364T1/de active
-
2011
- 2011-01-20 JP JP2011009922A patent/JP2011120596A/ja not_active Withdrawn
Also Published As
| Publication number | Publication date |
|---|---|
| EP1155120A1 (de) | 2001-11-21 |
| JP2011120596A (ja) | 2011-06-23 |
| DE60029195D1 (de) | 2006-08-17 |
| EP1155120B1 (de) | 2006-07-05 |
| DE60029195T2 (de) | 2007-06-28 |
| AU2811800A (en) | 2000-09-14 |
| AU774437B2 (en) | 2004-06-24 |
| JP2002536992A (ja) | 2002-11-05 |
| CA2364934C (fr) | 2011-10-18 |
| JP4802366B2 (ja) | 2011-10-26 |
| WO2000050573A1 (fr) | 2000-08-31 |
| CA2364934A1 (fr) | 2000-08-31 |
| US7264958B1 (en) | 2007-09-04 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification |
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