ATE332702T1 - Verwendung von glu-trp dipeptiden zur herstellung eines arzneimittels zur behandlung von verschiedenen gefässneubildung-assozierten erkrankungen - Google Patents

Verwendung von glu-trp dipeptiden zur herstellung eines arzneimittels zur behandlung von verschiedenen gefässneubildung-assozierten erkrankungen

Info

Publication number
ATE332702T1
ATE332702T1 AT96934021T AT96934021T ATE332702T1 AT E332702 T1 ATE332702 T1 AT E332702T1 AT 96934021 T AT96934021 T AT 96934021T AT 96934021 T AT96934021 T AT 96934021T AT E332702 T1 ATE332702 T1 AT E332702T1
Authority
AT
Austria
Prior art keywords
glu
treatment
production
associated diseases
medicinal product
Prior art date
Application number
AT96934021T
Other languages
English (en)
Inventor
Lawrence R Green
John W Blasecki
Original Assignee
Cytran Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cytran Ltd filed Critical Cytran Ltd
Application granted granted Critical
Publication of ATE332702T1 publication Critical patent/ATE332702T1/de

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/05—Dipeptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06008—Dipeptides with the first amino acid being neutral
    • C07K5/06017—Dipeptides with the first amino acid being neutral and aliphatic
    • C07K5/06034—Dipeptides with the first amino acid being neutral and aliphatic the side chain containing 2 to 4 carbon atoms

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Public Health (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Epidemiology (AREA)
  • Biophysics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biochemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Plant Substances (AREA)
AT96934021T 1995-10-03 1996-10-02 Verwendung von glu-trp dipeptiden zur herstellung eines arzneimittels zur behandlung von verschiedenen gefässneubildung-assozierten erkrankungen ATE332702T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US53870195A 1995-10-03 1995-10-03
US08/614,764 US5902790A (en) 1995-10-03 1996-03-13 Pharmaceutical angiostatic dipeptide compositions and method of use thereof

Publications (1)

Publication Number Publication Date
ATE332702T1 true ATE332702T1 (de) 2006-08-15

Family

ID=27065900

Family Applications (1)

Application Number Title Priority Date Filing Date
AT96934021T ATE332702T1 (de) 1995-10-03 1996-10-02 Verwendung von glu-trp dipeptiden zur herstellung eines arzneimittels zur behandlung von verschiedenen gefässneubildung-assozierten erkrankungen

Country Status (23)

Country Link
US (4) US5902790A (de)
EP (1) EP0869808B1 (de)
JP (2) JP3679129B2 (de)
KR (1) KR100483779B1 (de)
CN (1) CN1128636C (de)
AT (1) ATE332702T1 (de)
AU (1) AU714846B2 (de)
BR (1) BR9610838A (de)
CA (1) CA2233457C (de)
CZ (1) CZ298345B6 (de)
DE (1) DE69636343T2 (de)
DK (1) DK0869808T3 (de)
EA (1) EA001146B1 (de)
ES (1) ES2268710T3 (de)
HU (1) HUP9902105A3 (de)
IL (1) IL123889A0 (de)
MX (1) MX9802564A (de)
NO (1) NO326298B1 (de)
NZ (1) NZ319907A (de)
PL (1) PL186123B1 (de)
SK (1) SK283677B6 (de)
TR (1) TR199800653T1 (de)
WO (1) WO1997012625A1 (de)

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CN100553636C (zh) 2000-08-04 2009-10-28 Dmi生物科学公司 二酮基哌嗪和包含它们的组合物的使用方法
CA2627862C (en) * 2001-01-02 2009-12-22 Imtm Gmbh Use of inhibitors of dipeptidyl peptidase iv (dp iv) in combination with inhibitors of alanyl-aminopeptidase (apn)
DE10100052A1 (de) * 2001-01-02 2002-07-11 Inst Medizintechnologie Magdeb Kombinierte Verwendung von Enzyminhibitoren und pharmazeutischen Zubereitungen daraus zur Therapie und Prophylaxe der Atheriosklerose
US20030087830A1 (en) * 2001-06-12 2003-05-08 Eric Dupont Low molecular weight components of cartilage, complexes of metals with amino acids, DI-peptides and analogs thereof; processes for preparation and therapeutic uses thereof
RU2213571C2 (ru) * 2001-11-30 2003-10-10 Филиппова Ольга Всеволодовна Антигипоксическое средство
WO2004030522A2 (en) 2002-10-02 2004-04-15 Dmi Biosciences, Inc. Diagnosis and monitoring of diseases
EP2517718B1 (de) 2003-05-15 2016-03-02 Ampio Pharmaceuticals, Inc. Behandlung von T-Zell-vermittelten Krankheiten
WO2005016326A2 (en) * 2003-07-11 2005-02-24 The Government Of The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services Analogs of thalidomide as potential angiogenesis inhibitors
US7973057B2 (en) 2003-09-17 2011-07-05 The United States Of America As Represented By The Department Of Health And Human Services Thalidomide analogs
US8952895B2 (en) 2011-06-03 2015-02-10 Apple Inc. Motion-based device operations
US20080233053A1 (en) * 2005-02-07 2008-09-25 Pharmalight Inc. Method and Device for Ophthalmic Administration of Active Pharmaceutical Ingredients
CA2569204A1 (en) 2006-11-28 2008-05-28 Apotex Technologies Inc. Crystalline d-isoglutamyl-d-tryptophan and the mono ammonium salt of d-isoglutamyl-d-tryptophan
CA2571645A1 (en) 2006-12-19 2008-06-19 Apotex Technologies Inc. Pharmaceutically acceptable salts of thymodepressin and processes for their manufacture
KR20090119897A (ko) * 2007-02-13 2009-11-20 사이클론 파아머슈티컬 인코오퍼레이티드 점막의 질환으로 인한 조직 악화, 상처 또는 손상을 치료 또는 예방하는 방법
CA2579119C (en) 2007-02-16 2013-03-05 Apotex Technologies Inc. Crystalline forms of the mono-sodium salt of d-isoglutamyl-d-tryptophan
WO2009025830A1 (en) * 2007-08-23 2009-02-26 Sciclone Pharmaceuticals, Inc. Treatment of lung cancer
JP5856843B2 (ja) 2008-05-27 2016-02-10 アンピオ ファーマシューティカルズ，インコーポレイテッド ジケトピペラジンを用いた医薬組成物
DE102008032828A1 (de) * 2008-07-02 2010-01-07 Technische Universität Dresden Tryptophanhaltige Peptide aus alpha-Lactalbumin mit blutdrucksenkender und vasoprotektiver Wirkung für biofunktionelle Lebensmittel
EP2613786A4 (de) 2010-09-07 2013-10-23 Dmi Acquisition Corp Behandlung von erkrankungen
MY172699A (en) 2011-10-10 2019-12-10 Ampio Pharmaceuticals Inc Implantable medical devices with increased immune tolerance, and methods for making and implanting
EA028343B1 (ru) 2011-10-10 2017-11-30 Ампио Фармасьютикалз, Инк. Лечение дегенеративного заболевания сустава
EP2771007B1 (de) 2011-10-28 2018-04-04 Ampio Pharmaceuticals, Inc. Behandlung von rhinitis
US8927725B2 (en) 2011-12-02 2015-01-06 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Thio compounds
CN102631464B (zh) * 2012-05-18 2013-07-31 崔新明 一种治疗婴幼儿血管瘤的中药膏剂及其制备方法
BR112015020469A2 (pt) 2013-03-15 2020-01-28 Ampio Pharmaceuticals Inc Usos de da-dkp, composição e método para fornecimento de células-tronco a umindivíduo
RU2736513C2 (ru) 2014-08-18 2020-11-17 Ампио Фармасьютикалз, Инк. Лечение патологических состояний суставов
US9925233B2 (en) 2015-01-30 2018-03-27 Par Pharmaceutical, Inc. Vasopressin formulations for use in treatment of hypotension
US9687526B2 (en) 2015-01-30 2017-06-27 Par Pharmaceutical, Inc. Vasopressin formulations for use in treatment of hypotension
US9744239B2 (en) 2015-01-30 2017-08-29 Par Pharmaceutical, Inc. Vasopressin formulations for use in treatment of hypotension
US9750785B2 (en) 2015-01-30 2017-09-05 Par Pharmaceutical, Inc. Vasopressin formulations for use in treatment of hypotension
US9937223B2 (en) 2015-01-30 2018-04-10 Par Pharmaceutical, Inc. Vasopressin formulations for use in treatment of hypotension
US9744209B2 (en) 2015-01-30 2017-08-29 Par Pharmaceutical, Inc. Vasopressin formulations for use in treatment of hypotension
EP3310375A4 (de) 2015-06-22 2019-02-20 Ampio Pharmaceuticals, Inc. Verwendung von niedermolekularen fraktionen von humanem serumalbumin bei der behandlung von erkrankungen
SG11202001595SA (en) * 2017-08-31 2020-03-30 Singapore Health Serv Pte Ltd Angio-3 for treatment of retinal angiogenic diseases
CN116874557B (zh) * 2023-08-01 2024-12-20 首都医科大学 2-Trp-AA-四氢咔啉-3-羧酸类化合物及其PAF抑制剂的应用

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US5902790A (en) * 1995-10-03 1999-05-11 Cytran, Inc. Pharmaceutical angiostatic dipeptide compositions and method of use thereof
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ATE188219T1 (de) * 1991-10-28 2000-01-15 Cytran Ltd Pharmazeutische dipeptid zusammensetzungen und verwendungsmethoden.
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Also Published As

Publication number Publication date
EA001146B1 (ru) 2000-10-30
US20060094665A1 (en) 2006-05-04
BR9610838A (pt) 1999-12-21
DK0869808T3 (da) 2006-11-13
KR19990063958A (ko) 1999-07-26
NO326298B1 (no) 2008-11-03
WO1997012625A1 (en) 1997-04-10
CA2233457C (en) 2004-08-03
HUP9902105A3 (en) 2001-02-28
CA2233457A1 (en) 1997-04-10
SK42398A3 (en) 1998-10-07
US5902790A (en) 1999-05-11
NO981436D0 (no) 1998-03-30
CN1128636C (zh) 2003-11-26
US6911431B1 (en) 2005-06-28
NZ319907A (en) 2000-09-29
MX9802564A (es) 1998-11-30
TR199800653T1 (xx) 1998-06-22
DE69636343D1 (de) 2006-08-24
SK283677B6 (sk) 2003-11-04
EP0869808B1 (de) 2006-07-12
JP2005194287A (ja) 2005-07-21
IL123889A0 (en) 1998-10-30
EP0869808A1 (de) 1998-10-14
HUP9902105A2 (hu) 1999-09-28
AU7254096A (en) 1997-04-28
ES2268710T3 (es) 2007-03-16
US6096713A (en) 2000-08-01
JP3679129B2 (ja) 2005-08-03
PL326149A1 (en) 1998-08-31
NO981436L (no) 1998-05-19
JPH11504943A (ja) 1999-05-11
PL186123B1 (pl) 2003-10-31
AU714846B2 (en) 2000-01-13
CN1198673A (zh) 1998-11-11
CZ91398A3 (cs) 1998-11-11
EA199800357A1 (ru) 1998-10-29
DE69636343T2 (de) 2007-07-19
KR100483779B1 (ko) 2007-03-02
CZ298345B6 (cs) 2007-09-05

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