ATE332702T1 - Verwendung von glu-trp dipeptiden zur herstellung eines arzneimittels zur behandlung von verschiedenen gefässneubildung-assozierten erkrankungen - Google Patents
Verwendung von glu-trp dipeptiden zur herstellung eines arzneimittels zur behandlung von verschiedenen gefässneubildung-assozierten erkrankungenInfo
- Publication number
- ATE332702T1 ATE332702T1 AT96934021T AT96934021T ATE332702T1 AT E332702 T1 ATE332702 T1 AT E332702T1 AT 96934021 T AT96934021 T AT 96934021T AT 96934021 T AT96934021 T AT 96934021T AT E332702 T1 ATE332702 T1 AT E332702T1
- Authority
- AT
- Austria
- Prior art keywords
- glu
- treatment
- production
- associated diseases
- medicinal product
- Prior art date
Links
- 108010050025 alpha-glutamyltryptophan Proteins 0.000 title 1
- 201000010099 disease Diseases 0.000 title 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 title 1
- 229940126601 medicinal product Drugs 0.000 title 1
- 230000002792 vascular Effects 0.000 title 1
- 206010029113 Neovascularisation Diseases 0.000 abstract 1
- 230000002401 inhibitory effect Effects 0.000 abstract 1
- 239000000825 pharmaceutical preparation Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/05—Dipeptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/06—Dipeptides
- C07K5/06008—Dipeptides with the first amino acid being neutral
- C07K5/06017—Dipeptides with the first amino acid being neutral and aliphatic
- C07K5/06034—Dipeptides with the first amino acid being neutral and aliphatic the side chain containing 2 to 4 carbon atoms
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Organic Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Gastroenterology & Hepatology (AREA)
- Immunology (AREA)
- Epidemiology (AREA)
- Biochemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Medicinal Preparation (AREA)
- Medicines Containing Plant Substances (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US53870195A | 1995-10-03 | 1995-10-03 | |
| US08/614,764 US5902790A (en) | 1995-10-03 | 1996-03-13 | Pharmaceutical angiostatic dipeptide compositions and method of use thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE332702T1 true ATE332702T1 (de) | 2006-08-15 |
Family
ID=27065900
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT96934021T ATE332702T1 (de) | 1995-10-03 | 1996-10-02 | Verwendung von glu-trp dipeptiden zur herstellung eines arzneimittels zur behandlung von verschiedenen gefässneubildung-assozierten erkrankungen |
Country Status (23)
| Country | Link |
|---|---|
| US (4) | US5902790A (de) |
| EP (1) | EP0869808B1 (de) |
| JP (2) | JP3679129B2 (de) |
| KR (1) | KR100483779B1 (de) |
| CN (1) | CN1128636C (de) |
| AT (1) | ATE332702T1 (de) |
| AU (1) | AU714846B2 (de) |
| BR (1) | BR9610838A (de) |
| CA (1) | CA2233457C (de) |
| CZ (1) | CZ298345B6 (de) |
| DE (1) | DE69636343T2 (de) |
| DK (1) | DK0869808T3 (de) |
| EA (1) | EA001146B1 (de) |
| ES (1) | ES2268710T3 (de) |
| HU (1) | HUP9902105A3 (de) |
| IL (1) | IL123889A0 (de) |
| MX (1) | MX9802564A (de) |
| NO (1) | NO326298B1 (de) |
| NZ (1) | NZ319907A (de) |
| PL (1) | PL186123B1 (de) |
| SK (1) | SK283677B6 (de) |
| TR (1) | TR199800653T1 (de) |
| WO (1) | WO1997012625A1 (de) |
Families Citing this family (38)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5902790A (en) * | 1995-10-03 | 1999-05-11 | Cytran, Inc. | Pharmaceutical angiostatic dipeptide compositions and method of use thereof |
| US6060452A (en) * | 1996-03-13 | 2000-05-09 | Cytran, Inc. | Analogs of L-Glu-L-Trp having pharmacological activity |
| AU3467099A (en) * | 1998-04-03 | 1999-10-25 | Cytran Ltd. | Methods for production of therapeutic cytokines |
| JP5048201B2 (ja) | 2000-08-04 | 2012-10-17 | ディーエムアイ バイオサイエンシズ インコーポレイテッド | ジケトピペラジン類の使用方法とジケトピペラジン類を含む組成物 |
| DE10100052A1 (de) * | 2001-01-02 | 2002-07-11 | Inst Medizintechnologie Magdeb | Kombinierte Verwendung von Enzyminhibitoren und pharmazeutischen Zubereitungen daraus zur Therapie und Prophylaxe der Atheriosklerose |
| WO2002053170A2 (de) * | 2001-01-02 | 2002-07-11 | Institut Für Medizintechnologie Magdeburg Gmbh (Imtm) | Kombinierte verwendung von enzyminhibitoren und pharmazeutischen zubereitungen daraus zur therapie und prophylaxe der arteriosklerose, zur therapie und prävention allergischer reaktionen von typ i nach gell und coombs und zur therapie und prävention dermatologischer erkrankungen mit follikulären und epidermalen hyperkeratos |
| US20030087830A1 (en) * | 2001-06-12 | 2003-05-08 | Eric Dupont | Low molecular weight components of cartilage, complexes of metals with amino acids, DI-peptides and analogs thereof; processes for preparation and therapeutic uses thereof |
| RU2213571C2 (ru) * | 2001-11-30 | 2003-10-10 | Филиппова Ольга Всеволодовна | Антигипоксическое средство |
| DK1571970T3 (da) | 2002-10-02 | 2011-11-28 | Dmi Biosciences Inc | Diagnose og monitorering af sygdomme |
| CN102210852B (zh) | 2003-05-15 | 2016-10-19 | 安皮奥制药股份有限公司 | T-细胞介导的疾病的治疗 |
| WO2005016326A2 (en) * | 2003-07-11 | 2005-02-24 | The Government Of The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services | Analogs of thalidomide as potential angiogenesis inhibitors |
| CA2808646C (en) | 2003-09-17 | 2016-08-23 | The Government Of The United States Of America, As Represented By The Secretary Of The Department Of Health And Human Services | Thalidomide analogs as tnf-alpha modulators |
| US8952895B2 (en) | 2011-06-03 | 2015-02-10 | Apple Inc. | Motion-based device operations |
| US20080233053A1 (en) * | 2005-02-07 | 2008-09-25 | Pharmalight Inc. | Method and Device for Ophthalmic Administration of Active Pharmaceutical Ingredients |
| CA2569204A1 (en) | 2006-11-28 | 2008-05-28 | Apotex Technologies Inc. | Crystalline d-isoglutamyl-d-tryptophan and the mono ammonium salt of d-isoglutamyl-d-tryptophan |
| CA2571645A1 (en) * | 2006-12-19 | 2008-06-19 | Apotex Technologies Inc. | Pharmaceutically acceptable salts of thymodepressin and processes for their manufacture |
| MX2009008641A (es) * | 2007-02-13 | 2009-09-14 | Sciclone Pharmaceuticals Inc | Composiciones para el tratamiento o prevencion del deterioro, lesion o daño a tejido debido a enfermedad de las mucosas. |
| CA2579119C (en) * | 2007-02-16 | 2013-03-05 | Apotex Technologies Inc. | Crystalline forms of the mono-sodium salt of d-isoglutamyl-d-tryptophan |
| UA98508C2 (ru) * | 2007-08-23 | 2012-05-25 | Сайклон Фармасьютикалз, Инк. | Иммуномодуляторное производное дипептида для лечения рака легких |
| JP5856843B2 (ja) | 2008-05-27 | 2016-02-10 | アンピオ ファーマシューティカルズ,インコーポレイテッド | ジケトピペラジンを用いた医薬組成物 |
| DE102008032828A1 (de) * | 2008-07-02 | 2010-01-07 | Technische Universität Dresden | Tryptophanhaltige Peptide aus alpha-Lactalbumin mit blutdrucksenkender und vasoprotektiver Wirkung für biofunktionelle Lebensmittel |
| EP2613786A4 (de) | 2010-09-07 | 2013-10-23 | Dmi Acquisition Corp | Behandlung von erkrankungen |
| PH12014500685B1 (en) | 2011-10-10 | 2018-10-03 | Ampio Pharmaceuticals Inc | Treatment of degenerative joint disease |
| JP2014530063A (ja) | 2011-10-10 | 2014-11-17 | アンピオ ファーマシューティカルズ,インコーポレイテッド | 免疫寛容が高められた埋込み型医療用デバイス、ならびに製造方法および埋込み方法 |
| HK1198812A1 (en) | 2011-10-28 | 2015-06-12 | Ampio Pharmaceuticals, Inc. | Treatment of rhinitis |
| US8927725B2 (en) | 2011-12-02 | 2015-01-06 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Thio compounds |
| CN102631464B (zh) * | 2012-05-18 | 2013-07-31 | 崔新明 | 一种治疗婴幼儿血管瘤的中药膏剂及其制备方法 |
| CA2906864A1 (en) | 2013-03-15 | 2014-09-18 | Ampio Pharmaceuticals, Inc. | Compositions for the mobilization, homing, expansion and differentiation of stem cells and methods of using the same |
| EP4066836A1 (de) | 2014-08-18 | 2022-10-05 | Ampio Pharmaceuticals, Inc. | Behandlung von gelenkerkrankungen |
| US9925233B2 (en) | 2015-01-30 | 2018-03-27 | Par Pharmaceutical, Inc. | Vasopressin formulations for use in treatment of hypotension |
| US9375478B1 (en) | 2015-01-30 | 2016-06-28 | Par Pharmaceutical, Inc. | Vasopressin formulations for use in treatment of hypotension |
| US9937223B2 (en) | 2015-01-30 | 2018-04-10 | Par Pharmaceutical, Inc. | Vasopressin formulations for use in treatment of hypotension |
| US9687526B2 (en) | 2015-01-30 | 2017-06-27 | Par Pharmaceutical, Inc. | Vasopressin formulations for use in treatment of hypotension |
| US9750785B2 (en) | 2015-01-30 | 2017-09-05 | Par Pharmaceutical, Inc. | Vasopressin formulations for use in treatment of hypotension |
| US9744209B2 (en) | 2015-01-30 | 2017-08-29 | Par Pharmaceutical, Inc. | Vasopressin formulations for use in treatment of hypotension |
| EP3310375A4 (de) | 2015-06-22 | 2019-02-20 | Ampio Pharmaceuticals, Inc. | Verwendung von niedermolekularen fraktionen von humanem serumalbumin bei der behandlung von erkrankungen |
| JP2020532586A (ja) | 2017-08-31 | 2020-11-12 | シンガポール ヘルス サービシーズ プライベート リミテッド | 網膜血管性疾患の処置のためのangio−3 |
| CN116874557B (zh) * | 2023-08-01 | 2024-12-20 | 首都医科大学 | 2-Trp-AA-四氢咔啉-3-羧酸类化合物及其PAF抑制剂的应用 |
Family Cites Families (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3997516A (en) * | 1974-07-04 | 1976-12-14 | Takeda Chemical Industries, Ltd. | Method for protecting guanidino group and restoring the same |
| US4191753A (en) * | 1978-11-06 | 1980-03-04 | University Of Miami | Anti-hypertensive peptide analogs |
| US5728680A (en) * | 1987-12-30 | 1998-03-17 | Cytoven J.V. | Methods for normalizing numbers of lymphocytes |
| DE3873327D1 (de) * | 1987-12-30 | 1992-09-03 | Vsesojuznyj Kardiologitsches | Arzneimittelzubereitung zur behandlung des immunmangels. |
| GR1000608B (el) * | 1988-07-21 | 1992-08-31 | Erba Carlo Spa | Μεθοδος για την παρασκευη ανταγωνιστων bombesin. |
| SU1642398A1 (ru) * | 1988-12-21 | 1991-04-15 | Ростовский медицинский институт | Способ лечени синуитов у детей |
| US5770576A (en) * | 1989-08-30 | 1998-06-23 | Cytran, Inc. | Pharmaceutical dipeptide compositions and methods of use thereof: systemic toxicity |
| US5902790A (en) * | 1995-10-03 | 1999-05-11 | Cytran, Inc. | Pharmaceutical angiostatic dipeptide compositions and method of use thereof |
| RU1827255C (ru) * | 1990-10-22 | 1993-07-15 | Киевский государственный институт усовершенствования врачей | Способ лечени туберкулеза легких |
| JP3068656B2 (ja) * | 1991-03-07 | 2000-07-24 | アピ株式会社 | 新規なペプチド及びアンジオテンシン変換酵素阻害ペプチド並びにそれらを含有する経口摂食組成物 |
| WO1992017191A1 (en) * | 1991-04-01 | 1992-10-15 | Cytoven | Pharmaceutical dipeptide compositions and methods of use thereof |
| RU2014063C1 (ru) * | 1991-04-23 | 1994-06-15 | Сочинский научно-исследовательский институт курортологии и физиотерапии | Способ лечения подострых воспалительных заболеваний гениталий |
| DE69230500D1 (de) * | 1991-10-28 | 2000-02-03 | Cytran Ltd | Pharmazeutische Dipeptid Zusammensetzungen und Verwendungsmethoden. |
| AU7392294A (en) * | 1993-07-21 | 1995-02-20 | Vladimir Khatskelevich Khavinson | Pharmaceutical with immunomodulating activity |
| EP1333034B1 (de) * | 1993-09-24 | 2010-07-14 | University Of Southern California | Verwendung von Angiotensin-II-Analogen zur Gewebewiederherstellung |
-
1996
- 1996-03-13 US US08/614,764 patent/US5902790A/en not_active Expired - Lifetime
- 1996-10-02 EP EP96934021A patent/EP0869808B1/de not_active Expired - Lifetime
- 1996-10-02 DE DE69636343T patent/DE69636343T2/de not_active Expired - Lifetime
- 1996-10-02 JP JP51441597A patent/JP3679129B2/ja not_active Expired - Lifetime
- 1996-10-02 NZ NZ319907A patent/NZ319907A/xx not_active IP Right Cessation
- 1996-10-02 CA CA002233457A patent/CA2233457C/en not_active Expired - Lifetime
- 1996-10-02 BR BR9610838-0A patent/BR9610838A/pt not_active Application Discontinuation
- 1996-10-02 TR TR1998/00653T patent/TR199800653T1/xx unknown
- 1996-10-02 HU HU9902105A patent/HUP9902105A3/hu unknown
- 1996-10-02 AU AU72540/96A patent/AU714846B2/en not_active Expired
- 1996-10-02 AT AT96934021T patent/ATE332702T1/de not_active IP Right Cessation
- 1996-10-02 CZ CZ0091398A patent/CZ298345B6/cs not_active IP Right Cessation
- 1996-10-02 CN CN96197430A patent/CN1128636C/zh not_active Expired - Lifetime
- 1996-10-02 WO PCT/US1996/015856 patent/WO1997012625A1/en not_active Ceased
- 1996-10-02 SK SK423-98A patent/SK283677B6/sk not_active IP Right Cessation
- 1996-10-02 DK DK96934021T patent/DK0869808T3/da active
- 1996-10-02 IL IL12388996A patent/IL123889A0/xx unknown
- 1996-10-02 PL PL96326149A patent/PL186123B1/pl unknown
- 1996-10-02 KR KR1019980702431A patent/KR100483779B1/ko not_active Expired - Lifetime
- 1996-10-02 ES ES96934021T patent/ES2268710T3/es not_active Expired - Lifetime
- 1996-10-02 EA EA199800357A patent/EA001146B1/ru not_active IP Right Cessation
-
1998
- 1998-03-30 NO NO19981436A patent/NO326298B1/no not_active IP Right Cessation
- 1998-04-01 MX MX9802564A patent/MX9802564A/es unknown
-
1999
- 1999-03-01 US US09/260,190 patent/US6096713A/en not_active Expired - Lifetime
-
2000
- 2000-02-17 US US09/506,430 patent/US6911431B1/en not_active Expired - Fee Related
-
2005
- 2005-03-15 JP JP2005074079A patent/JP2005194287A/ja not_active Withdrawn
- 2005-05-16 US US11/129,367 patent/US20060094665A1/en not_active Abandoned
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |