ATE332711T1 - Eine neue komponente des 'hedgehog'- signalübertragungsweges - Google Patents

Eine neue komponente des 'hedgehog'- signalübertragungsweges

Info

Publication number
ATE332711T1
ATE332711T1 AT99956430T AT99956430T ATE332711T1 AT E332711 T1 ATE332711 T1 AT E332711T1 AT 99956430 T AT99956430 T AT 99956430T AT 99956430 T AT99956430 T AT 99956430T AT E332711 T1 ATE332711 T1 AT E332711T1
Authority
AT
Austria
Prior art keywords
ptch2
hedgehog
signal transmission
transmission path
new component
Prior art date
Application number
AT99956430T
Other languages
English (en)
Inventor
Peter G Zaphiropoulos
Anne Birgitte Unden
Rune Toftgard
Fahimeh Rahnama
Robert E Hollingsworth
Original Assignee
Karolinska Innovations Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Karolinska Innovations Ab filed Critical Karolinska Innovations Ab
Application granted granted Critical
Publication of ATE332711T1 publication Critical patent/ATE332711T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Cell Biology (AREA)
  • Immunology (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Psychology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Cable Transmission Systems, Equalization Of Radio And Reduction Of Echo (AREA)
  • Reduction Or Emphasis Of Bandwidth Of Signals (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
AT99956430T 1998-10-06 1999-10-06 Eine neue komponente des 'hedgehog'- signalübertragungsweges ATE332711T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SE9803393A SE9803393D0 (sv) 1998-10-06 1998-10-06 A novel component in the hedgehog signalling pathway

Publications (1)

Publication Number Publication Date
ATE332711T1 true ATE332711T1 (de) 2006-08-15

Family

ID=20412843

Family Applications (1)

Application Number Title Priority Date Filing Date
AT99956430T ATE332711T1 (de) 1998-10-06 1999-10-06 Eine neue komponente des 'hedgehog'- signalübertragungsweges

Country Status (9)

Country Link
US (2) US6881833B1 (de)
EP (1) EP1121157B1 (de)
JP (1) JP2002526050A (de)
AT (1) ATE332711T1 (de)
AU (1) AU1304400A (de)
DE (1) DE69932340T2 (de)
ES (1) ES2268886T3 (de)
SE (1) SE9803393D0 (de)
WO (1) WO2000020037A1 (de)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6709838B1 (en) * 1998-04-15 2004-03-23 Genentech, Inc. Nucleic acid encoding patched-2
WO2002046403A2 (en) * 2000-12-05 2002-06-13 Bayer Aktiengesellschaft Regulation of human patched-like protein

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6027882A (en) 1994-10-07 2000-02-22 The Regents Of The University Of California Patched genes and their use for diagnostics
EP0879888A3 (de) * 1997-05-23 1999-07-14 Smithkline Beecham Plc Patched-2 Polypeptide und Polynucleotide und Methoden zu ihrer Herstellung
EP1037982A1 (de) * 1997-12-08 2000-09-27 Ontogeny, Inc. Menschliche patched gene und proteine, und entsprechende verwendungen
US6709838B1 (en) * 1998-04-15 2004-03-23 Genentech, Inc. Nucleic acid encoding patched-2
US6348575B1 (en) * 1998-04-15 2002-02-19 Genentech, Inc. Patched-2

Also Published As

Publication number Publication date
EP1121157B1 (de) 2006-07-12
SE9803393D0 (sv) 1998-10-06
ES2268886T3 (es) 2007-03-16
WO2000020037A1 (en) 2000-04-13
EP1121157A1 (de) 2001-08-08
US20040146929A1 (en) 2004-07-29
DE69932340T2 (de) 2007-07-26
AU1304400A (en) 2000-04-26
DE69932340D1 (de) 2006-08-24
JP2002526050A (ja) 2002-08-20
US6881833B1 (en) 2005-04-19

Similar Documents

Publication Publication Date Title
WO2001062280A3 (en) Lipase-containing composition and methods of use thereof
WO2002024909A3 (en) Receptor nucleic acids and polypeptides
WO1999014346A3 (en) SENSE mRNA THERAPY
ATE484587T1 (de) Ldcam genannte moleküle
ATE297188T1 (de) Stabilisierte ascorbinsäure-lösungen
WO2002014485A3 (en) Kallikrein gene
WO2003048205A3 (fr) Proteines a activite inhibitrice de l'il-6
AU7303301A (en) Isolated nucleic acid molecules which encode t cell inducible factors, or interleukin-21, the proteins encoded, and uses thereof
WO1998011234A3 (en) Human protein kinases
DK0793721T3 (da) Peptider, der er i stand til at binde sig til GAP-proteinets SH3-domæne, nukleotidsekvenser, der koder derfor, fremstilling og anvendelse deraf
WO2002049625A3 (en) Compounds that affect cd83 expression, pharmaceutical compositions comprising said compounds and methods for identifying said compounds
DE69932340D1 (de) Eine neue komponente des 'hedgehog'-signalübertragungsweges
BR9711540A (pt) Inibidores de protease proteìnico estabilizados e variantes dos mesmos
WO2002022661A3 (en) NOVEL PDEs AND USES THEREOF
EP1151089A4 (de) Katalytische moleküle
DK0939769T3 (da) Vertebrat-Smoothened-proteiner
WO2001059120A3 (en) Il-17 like molecules and uses thereof
WO2001036626A3 (en) Pentraxin i and pentraxin receptor, inhibitors of said proteins and pharmaceutical compositions containing said compounds
DE69812438D1 (de) Zusammensetzung zur herstellung von brennstoff-briketts
WO1999002724A3 (en) Methods for identifying genes expressed in selected lineages, and a novel genes identified using the methods
WO2002024727A3 (en) New inhibitors of iapp fibril formation and uses thereof
WO1997046673A3 (en) Inhibition of hiv-1 replication by antisense rna expression
EP1097999A3 (de) An das durch Abscisinsäure-aktivierbare-Element bindende Transkriptionsfaktoren
DE60104789D1 (de) Verfahren zur Herstellung von 2,4,5-Trialkylbenzaldehyden
DE60004931D1 (de) Kontinuierliches Verfahren zur Herstellung von 3,5,5-Trimethylcyclohexa-3-en-1-on(beta-Isophoron)

Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties