ATE333897T1 - Arzneimittel mit chymaseinhibitoren als wirksames mittel zur behandlung von dermatitis mit zweiphasigen hautreaktionen - Google Patents

Arzneimittel mit chymaseinhibitoren als wirksames mittel zur behandlung von dermatitis mit zweiphasigen hautreaktionen

Info

Publication number
ATE333897T1
ATE333897T1 AT01906226T AT01906226T ATE333897T1 AT E333897 T1 ATE333897 T1 AT E333897T1 AT 01906226 T AT01906226 T AT 01906226T AT 01906226 T AT01906226 T AT 01906226T AT E333897 T1 ATE333897 T1 AT E333897T1
Authority
AT
Austria
Prior art keywords
dermatitis
treatment
chymasine
inhibitors
effective agent
Prior art date
Application number
AT01906226T
Other languages
English (en)
Inventor
Harukazu Fukami
Yoshiaki Tomimori
Yoshiaki Fukuda
Naohiro Watanabe
Original Assignee
Daiichi Asubio Pharma Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Daiichi Asubio Pharma Co Ltd filed Critical Daiichi Asubio Pharma Co Ltd
Application granted granted Critical
Publication of ATE333897T1 publication Critical patent/ATE333897T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/517—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with carbocyclic ring systems, e.g. quinazoline, perimidine
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/70—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
    • C07D239/72—Quinazolines; Hydrogenated quinazolines
    • C07D239/95—Quinazolines; Hydrogenated quinazolines with hetero atoms directly attached in positions 2 and 4
    • C07D239/96—Two oxygen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/04—Antipruritics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Dermatology (AREA)
  • Transplantation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Plant Substances (AREA)
AT01906226T 2000-02-22 2001-02-22 Arzneimittel mit chymaseinhibitoren als wirksames mittel zur behandlung von dermatitis mit zweiphasigen hautreaktionen ATE333897T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP2000050504 2000-02-22

Publications (1)

Publication Number Publication Date
ATE333897T1 true ATE333897T1 (de) 2006-08-15

Family

ID=18572276

Family Applications (1)

Application Number Title Priority Date Filing Date
AT01906226T ATE333897T1 (de) 2000-02-22 2001-02-22 Arzneimittel mit chymaseinhibitoren als wirksames mittel zur behandlung von dermatitis mit zweiphasigen hautreaktionen

Country Status (11)

Country Link
US (2) US7618977B2 (de)
EP (1) EP1192950B1 (de)
KR (1) KR20010109356A (de)
CN (1) CN1245979C (de)
AT (1) ATE333897T1 (de)
AU (1) AU3413601A (de)
CA (1) CA2368382A1 (de)
DE (1) DE60121695T2 (de)
ES (1) ES2269347T3 (de)
HU (1) HUP0201282A3 (de)
WO (1) WO2001062294A1 (de)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1366461A (zh) 2000-02-22 2002-08-28 三得利株式会社 含有胃促胰酶抑制剂作为有效成分的预防或治疗纤维变性的药物
EP1174151B1 (de) 2000-02-22 2007-01-24 Daiichi Asubio Pharma Co., Ltd. Therapeutische behandlung von eosinophilie durch verwendung von chymase-inhibitoren als aktiven bestandteilen
US7361767B2 (en) * 2003-11-14 2008-04-22 3M Innovative Properties Company N-sulfonyldicarboximide containing tethering compounds
CN101160290B (zh) 2004-12-02 2011-01-19 第一三共株式会社 7-元环化合物、其制备方法和药物用途
JP4842256B2 (ja) 2005-04-04 2011-12-21 第一三共株式会社 遺伝子一塩基多型解析によるアトピー性皮膚炎の相対罹患危険率の検出方法
AU2007268507B2 (en) 2006-05-31 2012-01-19 Daiichi Sankyo Company, Limited Seven-membered ring compound, production method thereof and pharmaceutical use thereof
EP3066096A1 (de) * 2013-11-08 2016-09-14 Bayer Pharma Aktiengesellschaft Substituierte uracile als chymase inhibitoren
AU2017416068A1 (en) 2017-05-24 2019-10-31 The Provost, Fellows, Foundation Scholars, And Other Members Of Board, Of The College Of The Holy And Undivided Trinity Of Queen Elizabeth Near Dublin Novel compounds and uses
EP3719130A4 (de) * 2017-11-30 2021-11-24 Ribomic Inc. Anti-chymase-aptamer und verwendung davon

Family Cites Families (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4684654A (en) * 1985-08-14 1987-08-04 American Cyanamid Company 3-heteroalkyl-2,4-quinzaolinediones
IL79249A (en) * 1986-06-26 1992-02-16 Makhteshim Chem Works Ltd Herbicidal compositions containing haloalkylthioquinazoline di(thi)ones and some new such compounds
JP2832923B2 (ja) * 1990-07-13 1998-12-09 吉富製薬株式会社 スチリル化合物およびその医薬用途
IE913473A1 (en) * 1990-10-15 1992-04-22 Fujisawa Pharmaceutical Co Quinazoline derivatives and their preparation
US5199279A (en) 1991-08-13 1993-04-06 Reynolds Martin M Drum contact freezer system and method
JPH05294930A (ja) * 1992-04-21 1993-11-09 Yoshitomi Pharmaceut Ind Ltd スチリル化合物
EP0644892A1 (de) 1992-06-12 1995-03-29 Pfizer Inc. Inhibitoren für Angiotensin I-Chymasen inklusive der menschlichen Herzchymase
WO1994026722A1 (en) 1993-05-12 1994-11-24 E.I. Du Pont De Nemours And Company Fungicidal fused bicyclic pyrimidinones
AU3086095A (en) * 1994-07-29 1996-03-04 Suntory Limited Imidazolidine derivative and use thereof
EP0826671B1 (de) 1995-04-27 2004-12-29 Mitsubishi Pharma Corporation Heterocyclische amidverbindungen und deren medizinische verwendung
US5596111A (en) 1995-06-05 1997-01-21 North Dakota State University Method for preparation of carboxylic acids
DE69622148T2 (de) 1995-09-28 2002-10-31 Suntory Limited, Osaka Chinazozin derivate und deren verwendung
KR20000068354A (ko) 1996-09-06 2000-11-25 다께다 가즈히꼬 신규 아세트아미드 유도체 및 프로테아제 저해제
JPH1087493A (ja) * 1996-09-18 1998-04-07 Shionogi & Co Ltd セフェム系化合物を含有するキマーゼ阻害剤
JPH10101666A (ja) * 1996-10-02 1998-04-21 Shionogi & Co Ltd 新規ベンゾオキサシクロトリデシン化合物およびそれを含有する医薬組成物
EP0940400A4 (de) 1996-10-25 2002-10-02 Mitsubishi Pharma Corp Heterocyklische amidverbindungen und ihre medizinische anwendung
JPH10245384A (ja) * 1997-03-05 1998-09-14 Teijin Ltd 新規トリアジンスルホン誘導体
EP1055683A4 (de) 1998-02-17 2007-07-25 Nippon Kayaku Kk Neuartiges acetamid-derivat und verwendung desselben
HUP0103256A3 (en) 1998-07-15 2002-05-28 Teijin Ltd Thiobenzimidazole derivatives and pharmaceutical compositions containing the compounds
ES2259476T3 (es) 1998-08-21 2006-10-01 Daiichi Asubio Pharma Co., Ltd. Derivados de quinazolina y sus aplicaciones farmaceuticas.
JP2000247908A (ja) * 1999-03-01 2000-09-12 Welfide Corp かゆみ抑制剤
ATE360423T1 (de) 1999-11-01 2007-05-15 Daiichi Asubio Pharma Co Ltd Verwendung von chymase hemmern gegen vaskuläre lipidablagerung
EP1174151B1 (de) 2000-02-22 2007-01-24 Daiichi Asubio Pharma Co., Ltd. Therapeutische behandlung von eosinophilie durch verwendung von chymase-inhibitoren als aktiven bestandteilen
CN1366461A (zh) 2000-02-22 2002-08-28 三得利株式会社 含有胃促胰酶抑制剂作为有效成分的预防或治疗纤维变性的药物

Also Published As

Publication number Publication date
EP1192950A4 (de) 2003-01-22
AU3413601A (en) 2001-09-03
EP1192950B1 (de) 2006-07-26
CN1245979C (zh) 2006-03-22
EP1192950A1 (de) 2002-04-03
HUP0201282A3 (en) 2003-02-28
DE60121695D1 (de) 2006-09-07
DE60121695T2 (de) 2007-08-30
US20020183339A1 (en) 2002-12-05
WO2001062294A1 (en) 2001-08-30
ES2269347T3 (es) 2007-04-01
CN1366460A (zh) 2002-08-28
KR20010109356A (ko) 2001-12-08
HUP0201282A2 (hu) 2002-12-28
US7618977B2 (en) 2009-11-17
CA2368382A1 (en) 2001-08-30
US20100029695A1 (en) 2010-02-04

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