ATE333897T1 - Arzneimittel mit chymaseinhibitoren als wirksames mittel zur behandlung von dermatitis mit zweiphasigen hautreaktionen - Google Patents

Arzneimittel mit chymaseinhibitoren als wirksames mittel zur behandlung von dermatitis mit zweiphasigen hautreaktionen

Info

Publication number
ATE333897T1
ATE333897T1 AT01906226T AT01906226T ATE333897T1 AT E333897 T1 ATE333897 T1 AT E333897T1 AT 01906226 T AT01906226 T AT 01906226T AT 01906226 T AT01906226 T AT 01906226T AT E333897 T1 ATE333897 T1 AT E333897T1
Authority
AT
Austria
Prior art keywords
dermatitis
treatment
chymasine
inhibitors
effective agent
Prior art date
Application number
AT01906226T
Other languages
English (en)
Inventor
Harukazu Fukami
Yoshiaki Tomimori
Yoshiaki Fukuda
Naohiro Watanabe
Original Assignee
Daiichi Asubio Pharma Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Daiichi Asubio Pharma Co Ltd filed Critical Daiichi Asubio Pharma Co Ltd
Application granted granted Critical
Publication of ATE333897T1 publication Critical patent/ATE333897T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/517—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with carbocyclic ring systems, e.g. quinazoline, perimidine
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/70—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
    • C07D239/72—Quinazolines; Hydrogenated quinazolines
    • C07D239/95—Quinazolines; Hydrogenated quinazolines with hetero atoms directly attached in positions 2 and 4
    • C07D239/96—Two oxygen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/04—Antipruritics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Dermatology (AREA)
  • Immunology (AREA)
  • Transplantation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Plant Substances (AREA)
AT01906226T 2000-02-22 2001-02-22 Arzneimittel mit chymaseinhibitoren als wirksames mittel zur behandlung von dermatitis mit zweiphasigen hautreaktionen ATE333897T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP2000050504 2000-02-22

Publications (1)

Publication Number Publication Date
ATE333897T1 true ATE333897T1 (de) 2006-08-15

Family

ID=18572276

Family Applications (1)

Application Number Title Priority Date Filing Date
AT01906226T ATE333897T1 (de) 2000-02-22 2001-02-22 Arzneimittel mit chymaseinhibitoren als wirksames mittel zur behandlung von dermatitis mit zweiphasigen hautreaktionen

Country Status (11)

Country Link
US (2) US7618977B2 (de)
EP (1) EP1192950B1 (de)
KR (1) KR20010109356A (de)
CN (1) CN1245979C (de)
AT (1) ATE333897T1 (de)
AU (1) AU3413601A (de)
CA (1) CA2368382A1 (de)
DE (1) DE60121695T2 (de)
ES (1) ES2269347T3 (de)
HU (1) HUP0201282A3 (de)
WO (1) WO2001062294A1 (de)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1245978C (zh) 2000-02-22 2006-03-22 第一阿斯比奥制药株式会社 含有胃促胰酶抑制剂作为活性成分的预防和治疗各种与嗜酸性粒细胞增多有关的疾病的药物
AU3413401A (en) 2000-02-22 2001-09-03 Daiichi Asubio Pharma Co., Ltd. Preventive or therapeutic drugs for fibrosis containing chymase inhibitors as the active ingredient
US7361767B2 (en) * 2003-11-14 2008-04-22 3M Innovative Properties Company N-sulfonyldicarboximide containing tethering compounds
AU2005310490B2 (en) 2004-12-02 2012-01-19 Daiichi Sankyo Company, Limited 7-membered ring compound, process for producing the same, and medicinal use thereof
WO2006107031A1 (ja) * 2005-04-04 2006-10-12 Asubio Pharma Co., Ltd. 遺伝子一塩基多型解析によるアトピー性皮膚炎の相対罹患危険率の検出方法
JP5117382B2 (ja) 2006-05-31 2013-01-16 第一三共株式会社 ７員環化合物の製造方法
US9695131B2 (en) * 2013-11-08 2017-07-04 Bayer Pharma Aktiengesellschaft Substituted uracils as chymase inhibitors
US11840543B2 (en) 2017-05-24 2023-12-12 The University Of Queensland Compounds and uses
WO2019107532A1 (ja) * 2017-11-30 2019-06-06 株式会社リボミック キマーゼに対するアプタマー及びその使用

Family Cites Families (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4684654A (en) 1985-08-14 1987-08-04 American Cyanamid Company 3-heteroalkyl-2,4-quinzaolinediones
IL79249A (en) 1986-06-26 1992-02-16 Makhteshim Chem Works Ltd Herbicidal compositions containing haloalkylthioquinazoline di(thi)ones and some new such compounds
JP2832923B2 (ja) * 1990-07-13 1998-12-09 吉富製薬株式会社 スチリル化合物およびその医薬用途
IE913473A1 (en) * 1990-10-15 1992-04-22 Fujisawa Pharmaceutical Co Quinazoline derivatives and their preparation
US5199279A (en) 1991-08-13 1993-04-06 Reynolds Martin M Drum contact freezer system and method
JPH05294930A (ja) * 1992-04-21 1993-11-09 Yoshitomi Pharmaceut Ind Ltd スチリル化合物
CA2137832C (en) 1992-06-12 2000-09-26 Dennis J. Hoover Inhibitors of angiotensin i chymase(s) including human heart chymase
CN1050355C (zh) 1993-05-12 2000-03-15 纳幕尔杜邦公司 稠合双环嘧啶酮类化合物、含有它们的杀真菌组合物及其应用
WO1996004248A1 (en) 1994-07-29 1996-02-15 Suntory Limited Imidazolidine derivative and use thereof
US5948785A (en) 1995-04-27 1999-09-07 The Green Cross Corporation Heterocyclic amide compounds and pharmaceutical use of the same
US5596111A (en) 1995-06-05 1997-01-21 North Dakota State University Method for preparation of carboxylic acids
WO1997011941A1 (fr) 1995-09-28 1997-04-03 Suntory Limited Derives de la quinazoline et leurs emplois
JP4199309B2 (ja) 1996-09-06 2008-12-17 日本化薬株式会社 新規アセトアミド誘導体およびプロテアーゼ阻害
JPH1087493A (ja) * 1996-09-18 1998-04-07 Shionogi & Co Ltd セフェム系化合物を含有するキマーゼ阻害剤
JPH10101666A (ja) * 1996-10-02 1998-04-21 Shionogi & Co Ltd 新規ベンゾオキサシクロトリデシン化合物およびそれを含有する医薬組成物
KR20000052775A (ko) 1996-10-25 2000-08-25 가마쿠라 아키오 신규한 헤테로사이클릭 아미드 화합물 및 의약으로서의 그의 용도
JPH10245384A (ja) * 1997-03-05 1998-09-14 Teijin Ltd 新規トリアジンスルホン誘導体
EP1055683A4 (de) 1998-02-17 2007-07-25 Nippon Kayaku Kk Neuartiges acetamid-derivat und verwendung desselben
HUP0103256A3 (en) 1998-07-15 2002-05-28 Teijin Ltd Thiobenzimidazole derivatives and pharmaceutical compositions containing the compounds
HUP0103387A3 (en) 1998-08-21 2002-07-29 Daiichi Asubio Pharma Co Ltd Quinazoline derivatives preparation thereof, medicament containing them and their intermediates
JP2000247908A (ja) * 1999-03-01 2000-09-12 Welfide Corp かゆみ抑制剤
US6921766B1 (en) 1999-11-01 2005-07-26 Daiichi Suntory Pharma Co., Ltd. Blood vessel lipid deposition-preventive agent comprising chymase-inhibitor
CN1245978C (zh) 2000-02-22 2006-03-22 第一阿斯比奥制药株式会社 含有胃促胰酶抑制剂作为活性成分的预防和治疗各种与嗜酸性粒细胞增多有关的疾病的药物
AU3413401A (en) 2000-02-22 2001-09-03 Daiichi Asubio Pharma Co., Ltd. Preventive or therapeutic drugs for fibrosis containing chymase inhibitors as the active ingredient

Also Published As

Publication number Publication date
US20020183339A1 (en) 2002-12-05
ES2269347T3 (es) 2007-04-01
CN1245979C (zh) 2006-03-22
AU3413601A (en) 2001-09-03
KR20010109356A (ko) 2001-12-08
US7618977B2 (en) 2009-11-17
US20100029695A1 (en) 2010-02-04
EP1192950B1 (de) 2006-07-26
CA2368382A1 (en) 2001-08-30
HUP0201282A2 (hu) 2002-12-28
DE60121695D1 (de) 2006-09-07
DE60121695T2 (de) 2007-08-30
CN1366460A (zh) 2002-08-28
WO2001062294A1 (en) 2001-08-30
HUP0201282A3 (en) 2003-02-28
EP1192950A4 (de) 2003-01-22
EP1192950A1 (de) 2002-04-03

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