ATE333897T1 - Arzneimittel mit chymaseinhibitoren als wirksames mittel zur behandlung von dermatitis mit zweiphasigen hautreaktionen - Google Patents

Arzneimittel mit chymaseinhibitoren als wirksames mittel zur behandlung von dermatitis mit zweiphasigen hautreaktionen

Info

Publication number
ATE333897T1
ATE333897T1 AT01906226T AT01906226T ATE333897T1 AT E333897 T1 ATE333897 T1 AT E333897T1 AT 01906226 T AT01906226 T AT 01906226T AT 01906226 T AT01906226 T AT 01906226T AT E333897 T1 ATE333897 T1 AT E333897T1
Authority
AT
Austria
Prior art keywords
dermatitis
treatment
chymasine
inhibitors
effective agent
Prior art date
Application number
AT01906226T
Other languages
English (en)
Inventor
Harukazu Fukami
Yoshiaki Tomimori
Yoshiaki Fukuda
Naohiro Watanabe
Original Assignee
Daiichi Asubio Pharma Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Daiichi Asubio Pharma Co Ltd filed Critical Daiichi Asubio Pharma Co Ltd
Application granted granted Critical
Publication of ATE333897T1 publication Critical patent/ATE333897T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/517—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with carbocyclic ring systems, e.g. quinazoline, perimidine
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/70—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
    • C07D239/72—Quinazolines; Hydrogenated quinazolines
    • C07D239/95—Quinazolines; Hydrogenated quinazolines with hetero atoms directly attached in positions 2 and 4
    • C07D239/96—Two oxygen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/04—Antipruritics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Dermatology (AREA)
  • Transplantation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Plant Substances (AREA)
AT01906226T 2000-02-22 2001-02-22 Arzneimittel mit chymaseinhibitoren als wirksames mittel zur behandlung von dermatitis mit zweiphasigen hautreaktionen ATE333897T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP2000050504 2000-02-22

Publications (1)

Publication Number Publication Date
ATE333897T1 true ATE333897T1 (de) 2006-08-15

Family

ID=18572276

Family Applications (1)

Application Number Title Priority Date Filing Date
AT01906226T ATE333897T1 (de) 2000-02-22 2001-02-22 Arzneimittel mit chymaseinhibitoren als wirksames mittel zur behandlung von dermatitis mit zweiphasigen hautreaktionen

Country Status (11)

Country Link
US (2) US7618977B2 (de)
EP (1) EP1192950B1 (de)
KR (1) KR20010109356A (de)
CN (1) CN1245979C (de)
AT (1) ATE333897T1 (de)
AU (1) AU3413601A (de)
CA (1) CA2368382A1 (de)
DE (1) DE60121695T2 (de)
ES (1) ES2269347T3 (de)
HU (1) HUP0201282A3 (de)
WO (1) WO2001062294A1 (de)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE60126199T2 (de) 2000-02-22 2008-02-28 Asubio Pharma Co., Ltd. Therapeutische behandlung von eosinophilie durch verwendung von chymase-inhibitoren als aktive bestandteile
CN1366461A (zh) 2000-02-22 2002-08-28 三得利株式会社 含有胃促胰酶抑制剂作为有效成分的预防或治疗纤维变性的药物
US7361767B2 (en) * 2003-11-14 2008-04-22 3M Innovative Properties Company N-sulfonyldicarboximide containing tethering compounds
WO2006059801A1 (ja) 2004-12-02 2006-06-08 Asubio Pharma Co., Ltd. ７員環化合物並びにその製造法および医薬用途
WO2006107031A1 (ja) 2005-04-04 2006-10-12 Asubio Pharma Co., Ltd. 遺伝子一塩基多型解析によるアトピー性皮膚炎の相対罹患危険率の検出方法
BRPI0712721A2 (pt) 2006-05-31 2012-11-20 Asubio Pharma Co Ltd composto de anel de 7 membros e mÉtodo de produÇço e aplicaÇço farmacÊutica do mesmo
HK1224288A1 (zh) * 2013-11-08 2017-08-18 Bayer Pharma Aktiengesellschaft 作为类糜蛋白酶抑制剂的取代的尿嘧啶
US11840543B2 (en) 2017-05-24 2023-12-12 The University Of Queensland Compounds and uses
KR20200090869A (ko) * 2017-11-30 2020-07-29 가부시키가이샤 리보믹 항-키마제 압타머 및 그의 용도

Family Cites Families (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4684654A (en) * 1985-08-14 1987-08-04 American Cyanamid Company 3-heteroalkyl-2,4-quinzaolinediones
IL79249A (en) * 1986-06-26 1992-02-16 Makhteshim Chem Works Ltd Herbicidal compositions containing haloalkylthioquinazoline di(thi)ones and some new such compounds
JP2832923B2 (ja) * 1990-07-13 1998-12-09 吉富製薬株式会社 スチリル化合物およびその医薬用途
IE913473A1 (en) * 1990-10-15 1992-04-22 Fujisawa Pharmaceutical Co Quinazoline derivatives and their preparation
US5199279A (en) 1991-08-13 1993-04-06 Reynolds Martin M Drum contact freezer system and method
JPH05294930A (ja) * 1992-04-21 1993-11-09 Yoshitomi Pharmaceut Ind Ltd スチリル化合物
WO1993025574A1 (en) 1992-06-12 1993-12-23 Pfizer Inc. Inhibitors of angiotensin i chymase(s) including human heart chymase
ES2163445T3 (es) 1993-05-12 2002-02-01 Du Pont Pirimidinonas biciclicas fusionadas con actividad fungicida.
AU3086095A (en) 1994-07-29 1996-03-04 Suntory Limited Imidazolidine derivative and use thereof
CA2219364A1 (en) 1995-04-27 1996-10-31 Hideki Okunishi Heterocyclic amide compounds and pharmaceutical use thereof
US5596111A (en) 1995-06-05 1997-01-21 North Dakota State University Method for preparation of carboxylic acids
EP0795548B1 (de) * 1995-09-28 2002-07-03 Suntory Limited Chinazozin derivate und deren verwendung
AU723234B2 (en) 1996-09-06 2000-08-24 Nippon Kayaku Kabushiki Kaisha Novel acetamide derivatives and protease inhibitors
JPH1087493A (ja) * 1996-09-18 1998-04-07 Shionogi & Co Ltd セフェム系化合物を含有するキマーゼ阻害剤
JPH10101666A (ja) * 1996-10-02 1998-04-21 Shionogi & Co Ltd 新規ベンゾオキサシクロトリデシン化合物およびそれを含有する医薬組成物
CN1088706C (zh) 1996-10-25 2002-08-07 卫福有限公司 新型杂环酰胺化合物及其医药用途
JPH10245384A (ja) * 1997-03-05 1998-09-14 Teijin Ltd 新規トリアジンスルホン誘導体
CN1209368C (zh) 1998-02-17 2005-07-06 日本化药株式会社 新的乙酰胺衍生物及其用途
PL203730B1 (pl) 1998-07-15 2009-11-30 Teijin Ltd Pochodna tiobenzimidazolu, kompozycja farmaceutyczna i jej zastosowanie
ATE326451T1 (de) 1998-08-21 2006-06-15 Daiichi Asubio Pharma Co Ltd Chinazolin derivate und therapeutische verwendungen davon
JP2000247908A (ja) * 1999-03-01 2000-09-12 Welfide Corp かゆみ抑制剤
HUP0104952A3 (en) 1999-11-01 2006-02-28 Daiichi Asubio Pharma Co Ltd Inhibitors against vascular lipid deposition containing chymase-inhibiting substances
DE60126199T2 (de) 2000-02-22 2008-02-28 Asubio Pharma Co., Ltd. Therapeutische behandlung von eosinophilie durch verwendung von chymase-inhibitoren als aktive bestandteile
CN1366461A (zh) 2000-02-22 2002-08-28 三得利株式会社 含有胃促胰酶抑制剂作为有效成分的预防或治疗纤维变性的药物

Also Published As

Publication number Publication date
WO2001062294A1 (en) 2001-08-30
EP1192950A4 (de) 2003-01-22
EP1192950B1 (de) 2006-07-26
US7618977B2 (en) 2009-11-17
KR20010109356A (ko) 2001-12-08
US20020183339A1 (en) 2002-12-05
CA2368382A1 (en) 2001-08-30
HUP0201282A2 (hu) 2002-12-28
CN1245979C (zh) 2006-03-22
HUP0201282A3 (en) 2003-02-28
ES2269347T3 (es) 2007-04-01
DE60121695D1 (de) 2006-09-07
US20100029695A1 (en) 2010-02-04
CN1366460A (zh) 2002-08-28
AU3413601A (en) 2001-09-03
DE60121695T2 (de) 2007-08-30
EP1192950A1 (de) 2002-04-03

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