ATE334121T1 - Verfahren zur herstellung von threo-1,2-epoxy-3- amino-4-phenylbutan-derivaten - Google Patents

Verfahren zur herstellung von threo-1,2-epoxy-3- amino-4-phenylbutan-derivaten

Info

Publication number: ATE334121T1
Authority: AT; Austria
Prior art keywords: amino; epoxy; threo; phenylbutane; derivatives
Prior art date: 1999-01-29

Application number

AT00901998T

Other languages

English (en)

Inventor

Katsuji Maehara

Yukinori Tokuda

Hiroshi Murao

Yasuyoshi Ueda

Original Assignee

Kaneka Corp

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1999-01-29

Filing date

2000-01-31

Publication date

2006-08-15

2000-01-31 Application filed by Kaneka Corp filed Critical Kaneka Corp

2006-08-15 Application granted granted Critical

2006-08-15 Publication of ATE334121T1 publication Critical patent/ATE334121T1/de

Links

238000004519 manufacturing process Methods 0.000 title abstract 2
239000003495 polar organic solvent Substances 0.000 abstract 2
239000002904 solvent Substances 0.000 abstract 1
XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D301/00—Preparation of oxiranes
- C07D301/02—Synthesis of the oxirane ring
- C07D301/24—Synthesis of the oxirane ring by splitting off HAL—Y from compounds containing the radical HAL—C—C—OY
- C07D301/26—Y being hydrogen
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D303/00—Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
- C07D303/02—Compounds containing oxirane rings
- C07D303/36—Compounds containing oxirane rings with hydrocarbon radicals, substituted by nitrogen atoms

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Epoxy Compounds (AREA)

AT00901998T 1999-01-29 2000-01-31 Verfahren zur herstellung von threo-1,2-epoxy-3- amino-4-phenylbutan-derivaten ATE334121T1 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
JP2164099		1999-01-29
JP23972099		1999-08-26

Publications (1)

Publication Number	Publication Date
ATE334121T1 true ATE334121T1 (de)	2006-08-15

Family

ID=26358729

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT00901998T ATE334121T1 (de)	1999-01-29	2000-01-31	Verfahren zur herstellung von threo-1,2-epoxy-3- amino-4-phenylbutan-derivaten

Country Status (8)

Country	Link
US (1)	US6344572B1 (de)
EP (2)	EP1067125B1 (de)
AT (1)	ATE334121T1 (de)
AU (1)	AU2322600A (de)
CA (1)	CA2325919C (de)
DE (1)	DE60029517T2 (de)
ES (1)	ES2267494T3 (de)
WO (1)	WO2000044736A1 (de)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
KR100708221B1 (ko)	1999-08-31	2007-04-17	아지노모토 가부시키가이샤	에폭사이드 결정의 제조방법
GB2369356B (en) *	2000-09-18	2004-02-04	Phoenix Chemicals Ltd	Process
JP4651178B2 (ja) *	2000-10-23	2011-03-16	三菱レイヨン株式会社	２−グリシジルオキシエチル（メタ）アクリレートの製造方法
JPWO2002044136A1 (ja)	2000-11-30	2004-04-02	味の素株式会社	Ｎ保護−β−アミノアルコールの製造法およびＮ保護−β−アミノエポキシドの製造法
US6764545B2 (en)	2000-12-12	2004-07-20	Ajinomoto Co., Inc.	Production method of epoxide crystal
US7527794B2 (en)	2001-07-31	2009-05-05	Wayne State University	Hybrid proteins with neuregulin heparin-binding domain for targeting to heparan sulfate proteoglycans
HRP20090488T1 (hr)	2003-12-23	2009-10-31	Tibotec Pharmaceuticals Ltd.	Postupak za pripravu (3r,3as,6ar)-heksahidrofuro[2,3-b]furan-3-il(1s,23)-3-[[(4-aminofenil)sulfonil](izobutil)amino]-1-benzil-2-hidroksipropilkarbamata
US7772411B2 (en)	2003-12-23	2010-08-10	Tibotec Pharmaceuticals Ltd.	Process for the preparation of (3R,3aS,6aR)-hexahydrofuro [2,3-b] furan-3-yl (1S,2R)-3[[(4-aminophenyl) sulfonyl] (isobutyl) amino]-1-benzyl-2-hydroxypropylcarbamate
US7582468B2 (en) *	2005-05-25	2009-09-01	Bristol-Myers Squibb Company	Process for preparing (2R,3S)-1,2-epoxy-3-(protected)amino-4-substituted butane and intermediates thereof
WO2008055970A2 (en)	2006-11-09	2008-05-15	Tibotec Pharmaceuticals Ltd.	Methods for the preparation of hexahydrofuro[2,3-b]furan-3-ol
PL2152667T3 (pl)	2007-04-27	2011-06-30	Tibotec Pharm Ltd	Sposoby wytwarzania pochodnych N-izobutylo-N-(2-hydroksy-3-amino-4-fenylo-butylo)-p-nitrobenzenosulfonyloamidu
AU2008268627A1 (en) *	2007-06-22	2008-12-31	Bristol-Myers Squibb Company	Tableted compositions containing atazanavir
US20100178340A1 (en) *	2007-06-22	2010-07-15	Bristol-Myers Squibb Company	Tableted compositions containing atazanavir
DE602008005896D1 (de) *	2007-06-22	2011-05-12	Bristol Myers Squibb Co	Tablettierte atazanavirhaltige zusammensetzungen
SI2170292T1 (sl) *	2007-06-22	2014-05-30	Bristol-Myers Squibb Holdings Ireland	Tabletirani sestavki, ki vsebujejo atazanavir
WO2009136365A1 (en) *	2008-05-08	2009-11-12	Ranbaxy Laboratories Limited	Process for the preparation of 3,4-epoxy-2-amino-1-substituted butane derivatives and intermediate compounds thereof
AR073248A1 (es)	2008-09-01	2010-10-20	Tibotec Pharm Ltd	Proceso para la preparacion de (1s, 2r)-3- ((4-aminofenil) sulfonil) ( isobutil) amino)-1- bencil-2- hidroxipropilcarbamato de (3r, 3as,6ar)- hexahidrofuro-(2,3-b) furan-3- ilo (darunavir) y compuestos intermediarios utiles en dicho proceso.
US8921415B2 (en)	2009-01-29	2014-12-30	Mapi Pharma Ltd.	Polymorphs of darunavir
CN102725295A (zh)	2010-01-28	2012-10-10	Mapi医药公司	制备达芦那韦和达芦那韦中间体的方法

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JPH07504654A (ja) *	1992-03-11	1995-05-25	ナルヘックス　リミテッド	オキソ及びヒドロキシ置換炭化水素のアミン誘導体
US5559256A (en) *	1992-07-20	1996-09-24	E. R. Squibb & Sons, Inc.	Aminediol protease inhibitors
US5481011A (en) *	1994-12-13	1996-01-02	Bristol-Myers Squibb Company	Process for preparing N-protected amino acid α-halomethyl ketones and alcohols from N-protected amino acid esters
US5929284A (en) *	1995-02-03	1999-07-27	Kaneka Corporation	Processes for producing α-halo ketones, α-halohydrins and epoxides
CA2190570C (en) *	1995-11-17	2005-05-03	Yutaka Honda	Process for producing 3-amino-2-oxo-1-halogenopropane derivatives
JPH09323960A (ja) *	1996-06-05	1997-12-16	Ajinomoto Co Inc	３−アミノ−１，２−オキシランの製造方法

2000
- 2000-01-31 EP EP00901998A patent/EP1067125B1/de not_active Expired - Lifetime
- 2000-01-31 DE DE60029517T patent/DE60029517T2/de not_active Expired - Lifetime
- 2000-01-31 US US09/647,340 patent/US6344572B1/en not_active Expired - Lifetime
- 2000-01-31 WO PCT/JP2000/000495 patent/WO2000044736A1/ja not_active Ceased
- 2000-01-31 CA CA002325919A patent/CA2325919C/en not_active Expired - Fee Related
- 2000-01-31 AU AU23226/00A patent/AU2322600A/en not_active Abandoned
- 2000-01-31 AT AT00901998T patent/ATE334121T1/de not_active IP Right Cessation
- 2000-01-31 ES ES00901998T patent/ES2267494T3/es not_active Expired - Lifetime
- 2000-01-31 EP EP06110625A patent/EP1661893A3/de not_active Withdrawn

Also Published As

Publication number	Publication date
DE60029517D1 (de)	2006-09-07
EP1067125A1 (de)	2001-01-10
EP1661893A2 (de)	2006-05-31
US6344572B1 (en)	2002-02-05
EP1661893A3 (de)	2006-06-07
ES2267494T3 (es)	2007-03-16
AU2322600A (en)	2000-08-18
DE60029517T2 (de)	2006-11-23
EP1067125A4 (de)	2004-06-16
EP1067125B1 (de)	2006-07-26
WO2000044736A1 (en)	2000-08-03
CA2325919A1 (en)	2000-08-03
CA2325919C (en)	2009-07-21

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Legal Events

Date	Code	Title	Description
2007-01-15	RER	Ceased as to paragraph 5 lit. 3 law introducing patent treaties