ATE334671T1 - Wortmanninanaloge und verfahren zu deren verwendung - Google Patents

Wortmanninanaloge und verfahren zu deren verwendung

Info

Publication number: ATE334671T1
Authority: AT; Austria
Prior art keywords: analogs; wordman; inhibiting; mammals; subject
Prior art date: 2001-09-14

Application number

AT02766286T

Other languages

English (en)

Inventor

Peter Wipf

Garth Powis

Original Assignee

Univ Arizona

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2001-09-14

Filing date

2002-09-16

Publication date

2006-08-15

2002-09-16 Application filed by Univ Arizona filed Critical Univ Arizona

2006-08-15 Application granted granted Critical

2006-08-15 Publication of ATE334671T1 publication Critical patent/ATE334671T1/de

Links

230000002401 inhibitory effect Effects 0.000 abstract 2
241000124008 Mammalia Species 0.000 abstract 1
102000003993 Phosphatidylinositol 3-kinases Human genes 0.000 abstract 1
108090000430 Phosphatidylinositol 3-kinases Proteins 0.000 abstract 1
230000000694 effects Effects 0.000 abstract 1
230000005740 tumor formation Effects 0.000 abstract 1
QDLHCMPXEPAAMD-QAIWCSMKSA-N wortmannin Chemical class C1([C@]2(C)C3=C(C4=O)OC=C3C(=O)O[C@@H]2COC)=C4[C@@H]2CCC(=O)[C@@]2(C)C[C@H]1OC(C)=O QDLHCMPXEPAAMD-QAIWCSMKSA-N 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/94—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems condensed with rings other than six-membered or with ring systems containing such rings
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
General Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
Chemical Kinetics & Catalysis (AREA)
Public Health (AREA)
Medicinal Chemistry (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Steroid Compounds (AREA)
Medicines Containing Plant Substances (AREA)
Distillation Of Fermentation Liquor, Processing Of Alcohols, Vinegar And Beer (AREA)
Compounds Of Unknown Constitution (AREA)
Pyrane Compounds (AREA)

AT02766286T 2001-09-14 2002-09-16 Wortmanninanaloge und verfahren zu deren verwendung ATE334671T1 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US32214301P	2001-09-14	2001-09-14
US32213901P	2001-09-14	2001-09-14

Publications (1)

Publication Number	Publication Date
ATE334671T1 true ATE334671T1 (de)	2006-08-15

Family

ID=26983283

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT02766286T ATE334671T1 (de)	2001-09-14	2002-09-16	Wortmanninanaloge und verfahren zu deren verwendung

Country Status (8)

Country	Link
EP (1)	EP1435941B8 (de)
JP (1)	JP4540986B2 (de)
AT (1)	ATE334671T1 (de)
AU (1)	AU2002330029B2 (de)
CA (1)	CA2458318C (de)
DE (1)	DE60213633T2 (de)
MX (1)	MXPA04002445A (de)
WO (1)	WO2003024183A2 (de)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US7081475B2 (en)	2001-09-14	2006-07-25	Prolx Pharmaceuticals Corp.	Wortmannin analogs and methods of using same
DE10219545A1 (de) *	2002-04-26	2003-11-06	Lang Florian	Regulation der Apoptose
US7230139B2 (en)	2002-12-05	2007-06-12	Gemin X Biotechnologies	Diterpenoid compounds, compositions thereof and their use as anti-cancer or anti-fungal agents
WO2004093918A2 (en) *	2003-04-23	2004-11-04	Wyeth Holdings Corporation	Peg-wortmannin conjugates
DE102004043463A1 (de) *	2004-06-09	2006-02-09	Heinz Voigt	Mittel zur Krebsbekämpfung unter Verwendung von Schimmelpilzextrakten
WO2007008200A1 (en) *	2004-07-09	2007-01-18	Prolx Pharmaceuticals Corp.	Wortmannin analogs and methods of using same in combination with chemotherapeutic agents
TW200626610A (en)	2004-10-13	2006-08-01	Wyeth Corp	Analogs of 17-hydroxywortmannin as PI3K inhibitors
US8716299B2 (en) *	2004-12-20	2014-05-06	University Of South Florida	XIAP-targeted prostate cancer therapy
US20090324489A1 (en) *	2005-09-01	2009-12-31	Hushan Yuan	Wortmannin conjugates and uses thereof
US20070116736A1 (en) *	2005-11-23	2007-05-24	Argentieri Dennis C	Local vascular delivery of PI3 kinase inhibitors alone or in combination with sirolimus to prevent restinosis following vascular injury
ATE536181T1 (de)	2005-12-30	2011-12-15	Univ Arizona	Metabolite von wortmannin-analogen und verwendungsverfahren dafür
WO2007120897A2 (en) *	2006-04-13	2007-10-25	The Trustees Of Columbia University In The City Of New York	Compositions and intraluminal devices for inhibiting vascular stenosis
US20130131156A1 (en) *	2010-06-04	2013-05-23	Oncothyreon Inc.	Cancer Treatment with Wortmannin Analogs
WO2011153488A1 (en) *	2010-06-04	2011-12-08	Oncothyreon Inc.	Combination cancer therapies with wortmannin analogs
US11197854B1 (en)	2018-11-14	2021-12-14	National Technology & Engineering Solutions Of Sandia, Llc	Inhibitors for targeting flaviviruses
US20220040324A1 (en)	2018-12-21	2022-02-10	Daiichi Sankyo Company, Limited	Combination of antibody-drug conjugate and kinase inhibitor

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB2302021A (en) *	1996-10-16	1997-01-08	Lilly Co Eli	Inhibiting bone loss or resorption

2002
- 2002-09-16 CA CA2458318A patent/CA2458318C/en not_active Expired - Fee Related
- 2002-09-16 EP EP02766286A patent/EP1435941B8/de not_active Expired - Lifetime
- 2002-09-16 MX MXPA04002445A patent/MXPA04002445A/es active IP Right Grant
- 2002-09-16 AT AT02766286T patent/ATE334671T1/de not_active IP Right Cessation
- 2002-09-16 WO PCT/US2002/029365 patent/WO2003024183A2/en not_active Ceased
- 2002-09-16 JP JP2003528088A patent/JP4540986B2/ja not_active Expired - Fee Related
- 2002-09-16 DE DE60213633T patent/DE60213633T2/de not_active Expired - Lifetime
- 2002-09-16 AU AU2002330029A patent/AU2002330029B2/en not_active Ceased

Also Published As

Publication number	Publication date
CA2458318A1 (en)	2003-03-27
EP1435941A4 (de)	2004-12-08
MXPA04002445A (es)	2005-07-25
EP1435941B1 (de)	2006-08-02
EP1435941B8 (de)	2006-10-25
CA2458318C (en)	2011-03-15
WO2003024183A2 (en)	2003-03-27
JP2005507880A (ja)	2005-03-24
EP1435941A2 (de)	2004-07-14
AU2002330029B2 (en)	2006-07-06
JP4540986B2 (ja)	2010-09-08
DE60213633D1 (de)	2006-09-14
WO2003024183A3 (en)	2003-06-12
DE60213633T2 (de)	2007-11-08

Similar Documents

Publication	Publication Date	Title
ATE334671T1 (de)	2006-08-15	Wortmanninanaloge und verfahren zu deren verwendung
DE69815090D1 (de)	2003-07-03	Verwendung von cholinesterasehemmer zur behandlung von konzentrationsstörungen
ES2189235T3 (es)	2003-07-01	6-fenilfenantridinas sustituidas.
ATE323684T1 (de)	2006-05-15	Verfahren und zusammensetzungen unter verwendung von chinazolinonen
DE60044004D1 (de)	2010-04-22	Verwendung von Omega-Carboxyaryl-substituierten Diphenylharnstoffen als raf-Kinase-Inhibitoren
GB0209891D0 (en)	2002-06-05	Novel compounds
DE59905858D1 (de)	2003-07-10	Verwendung von pit-emulsionen
DE60334570D1 (de)	2010-11-25	Verfahren zu herstellung von metallnanoteilchen
TR200201638T2 (tr)	2002-11-21	Yeni imidazo[1,3,5]triazinonlar ve kullanımları
DE50212455D1 (de)	2008-08-14	Verwendung von Dimerdiolen
EP1565262A4 (de)	2009-11-11	VERFAHREN ZUR HERSTELLUNG EINER GETRûGERTEN AKTIVIERTEN KATALYSATOR ENTHALTENDEN ZUSAMMENSETZUNG
DE60221972D1 (de)	2007-10-04	Verfahren zur gewichtsverminderung von gipsbauplatten
NO994822D0 (no)	1999-10-04	Immunotolerant protrombinkomplekspreparat
NO996287D0 (no)	1999-12-17	Chalkoner med antiproliferativ aktivitet
DE50114181D1 (de)	2008-09-11	Verwendung von 1-phenyl-3-dimethylamino-propan-verbindungen zur therapie der harninkontinenz
DE60235589D1 (de)	2010-04-15	Wortmannin-Analoge und Verfahren zu deren Verwendung
ATE314066T1 (de)	2006-01-15	Verwendung von buprenorphin zur therapie der harninkontinenz
DE60011801D1 (de)	2004-07-29	Benzoxa- und benzthiazolylsulfamate sowie ihre verwendung als steroid-sulfataseinhibitoren
ATE314070T1 (de)	2006-01-15	Verwendung von pyridoindolonderivaten zur herstellung von antikrebsmitteln
IL148726A0 (en)	2002-09-12	Method of calculating correct religious hijri calendar
ATA16522002A (de)	2003-09-15	Verfahren zur bestimmung der aktivität von diaminooxidase
DE60127917D1 (de)	2007-05-31	Verwendung von gamma-CEHC als Antioxidantien
EP1965790A4 (de)	2009-06-24	Metabolite von wortmannin-analogen und verwendungsverfahren dafür
DE60116664D1 (de)	2006-04-06	Indolocarbazol-antikrebsmittel und verfahren zu ihrer verwendung
ATE345395T1 (de)	2006-12-15	Verfahren zur bestimmung der syntheseaktivität von hydrolasen

Legal Events

Date	Code	Title	Description
2007-02-15	RER	Ceased as to paragraph 5 lit. 3 law introducing patent treaties