ATE337035T1 - Verfahren zur isolierung und rückgewinnung von zellen - Google Patents

Verfahren zur isolierung und rückgewinnung von zellen

Info

Publication number
ATE337035T1
ATE337035T1 AT99118189T AT99118189T ATE337035T1 AT E337035 T1 ATE337035 T1 AT E337035T1 AT 99118189 T AT99118189 T AT 99118189T AT 99118189 T AT99118189 T AT 99118189T AT E337035 T1 ATE337035 T1 AT E337035T1
Authority
AT
Austria
Prior art keywords
filtering device
line
priming liquid
isolation
recovery
Prior art date
Application number
AT99118189T
Other languages
English (en)
Inventor
Yoshitaka Ohmura
Nakaimachi
Miyuki Shimizu
Tadashi Sameshima
Original Assignee
Terumo Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Terumo Corp filed Critical Terumo Corp
Application granted granted Critical
Publication of ATE337035T1 publication Critical patent/ATE337035T1/de

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D69/00—Semi-permeable membranes for separation processes or apparatus characterised by their form, structure or properties; Manufacturing processes specially adapted therefor
    • B01D69/12—Composite membranes; Ultra-thin membranes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/02—Blood transfusion apparatus
    • A61M1/0209—Multiple bag systems for separating or storing blood components
    • A61M1/0218—Multiple bag systems for separating or storing blood components with filters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/02—Blood transfusion apparatus
    • A61M1/0209—Multiple bag systems for separating or storing blood components
    • A61M1/0236—Multiple bag systems for separating or storing blood components with sampling means, e.g. sample bag or sampling port
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
    • A61M1/3621—Extra-corporeal blood circuits
    • A61M1/3627—Degassing devices; Buffer reservoirs; Drip chambers; Blood filters
    • A61M1/3633—Blood component filters, e.g. leukocyte filters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
    • A61M1/3621—Extra-corporeal blood circuits
    • A61M1/3643—Priming, rinsing before or after use
    • A61M1/3644—Mode of operation
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D61/00—Processes of separation using semi-permeable membranes, e.g. dialysis, osmosis or ultrafiltration; Apparatus, accessories or auxiliary operations specially adapted therefor
    • B01D61/14—Ultrafiltration; Microfiltration
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D69/00—Semi-permeable membranes for separation processes or apparatus characterised by their form, structure or properties; Manufacturing processes specially adapted therefor
    • B01D69/02—Semi-permeable membranes for separation processes or apparatus characterised by their form, structure or properties; Manufacturing processes specially adapted therefor characterised by their properties
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
    • A61M1/3621—Extra-corporeal blood circuits
    • A61M1/3643—Priming, rinsing before or after use
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2202/00—Special media to be introduced, removed or treated
    • A61M2202/04—Liquids
    • A61M2202/0413—Blood
    • A61M2202/0439—White blood cells; Leucocytes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/75—General characteristics of the apparatus with filters
    • A61M2205/7554—General characteristics of the apparatus with filters with means for unclogging or regenerating filters

Landscapes

  • Health & Medical Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Cardiology (AREA)
  • Water Supply & Treatment (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • External Artificial Organs (AREA)
  • Separation Using Semi-Permeable Membranes (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Sampling And Sample Adjustment (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
AT99118189T 1998-09-14 1999-09-13 Verfahren zur isolierung und rückgewinnung von zellen ATE337035T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP27936498A JP3517359B2 (ja) 1998-09-14 1998-09-14 細胞分離・回収装置および細胞の分離・回収方法

Publications (1)

Publication Number Publication Date
ATE337035T1 true ATE337035T1 (de) 2006-09-15

Family

ID=17610139

Family Applications (1)

Application Number Title Priority Date Filing Date
AT99118189T ATE337035T1 (de) 1998-09-14 1999-09-13 Verfahren zur isolierung und rückgewinnung von zellen

Country Status (5)

Country Link
US (1) US6312950B1 (de)
EP (1) EP0987034B1 (de)
JP (1) JP3517359B2 (de)
AT (1) ATE337035T1 (de)
DE (1) DE69932901T2 (de)

Families Citing this family (70)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6306350B1 (en) * 1999-05-19 2001-10-23 Itt Manufacturing Enterprises, Inc. Water sampling method and apparatus with analyte integration
AU2001229489A1 (en) * 2000-01-14 2001-07-24 Mykrolis Corporation System and method for liquid filtration based on a neutral filter material
EP1573416A4 (de) * 2000-07-07 2010-01-27 Fenwal Inc Medizinisches system, verfahren und gerät, das mems verwendet
US7311905B2 (en) 2002-02-13 2007-12-25 Anthrogenesis Corporation Embryonic-like stem cells derived from post-partum mammalian placenta, and uses and methods of treatment using said cells
DK1349918T3 (da) 2000-12-06 2014-11-10 Anthrogenesis Corp Fremgangsmåde til indsamling af stamceller fra moderkagen
EP2316919B1 (de) 2001-02-14 2015-10-07 Anthrogenesis Corporation Post-partum Säugetier-Plazenta, deren Verwendung und daraus gewonnene Stammzellen
FR2825261B1 (fr) * 2001-06-01 2003-09-12 Maco Pharma Sa Ligne de prelevement du sang placentaire comprenant une poche de rincage
US6623959B2 (en) 2001-06-13 2003-09-23 Ethicon, Inc. Devices and methods for cell harvesting
US7156803B2 (en) 2002-08-19 2007-01-02 Depuy Spine, Inc. Devices for controlling fluid flow through a medium
AU2003298775B2 (en) 2002-11-26 2008-07-17 Anthrogenesis Corporation Cytotherapeutics, cytotherapeutic units and methods for treatments using them
JP4158095B2 (ja) * 2003-01-15 2008-10-01 株式会社クニムネ 尿検体の採取・保存器具
US7601268B2 (en) * 2003-05-27 2009-10-13 Haemonetics Corporation Continuous blood filtration and method of use
JP2007017151A (ja) * 2003-09-30 2007-01-25 Dai Ichi Pure Chem Co Ltd フィルターホルダーとそれを装着した検査用フィルターユニット
DK1957633T3 (en) 2005-10-13 2014-03-17 Anthrogenesis Corp Immunomodulation USING PLACE SPEECH STEM CELLS
PT2471904T (pt) 2005-12-29 2019-02-25 Celularity Inc População de células estaminais placentárias
CN101389754A (zh) 2005-12-29 2009-03-18 人类起源公司 胎盘干细胞和第二来源干细胞的联合培养
EP3763376A1 (de) 2007-02-12 2021-01-13 Celularity, Inc. Behandlung von infektionskrankheiten mithilfe von plazenta-stammzellen
JP5243456B2 (ja) * 2007-03-02 2013-07-24 スミス アンド ネフュー ピーエルシー 生物学的サンプルろ過中の超音波、逆流洗浄、およびフィルタ運動によるフィルタ洗浄装置および方法
US9200253B1 (en) 2007-08-06 2015-12-01 Anthrogenesis Corporation Method of producing erythrocytes
NZ599825A (en) 2007-09-28 2014-10-31 Anthrogenesis Corp Tumor suppression using human placental perfusate and human placenta-derived intermediate natural killer cells
JP5441888B2 (ja) 2008-03-31 2014-03-12 シスメックス株式会社 試料調製装置及び試料調製方法、並びに、細胞分析装置及び細胞分析方法
JP5003614B2 (ja) * 2008-07-03 2012-08-15 株式会社日立プラントテクノロジー 生体細胞の分離方法及び培養装置
KR20240052847A (ko) 2008-08-20 2024-04-23 셀룰래리티 인코포레이티드 개선된 세포 조성물 및 그의 제조 방법
WO2010021715A1 (en) 2008-08-20 2010-02-25 Anthrogenesis Corporation Treatment of stroke using isolated placental cells
CA2734446C (en) 2008-08-22 2017-06-20 Anthrogenesis Corporation Methods and compositions for treatment of bone defects with placental cell populations
JP2010094266A (ja) * 2008-10-16 2010-04-30 Nipro Corp 体外循環モジュールのプライミング用液体およびプライミング方法
AU2009316541B2 (en) 2008-11-19 2015-08-06 Celularity Inc. Amnion derived adherent cells
JP6162359B2 (ja) * 2009-06-30 2017-07-12 株式会社カネカ 血液成分の分離システム、分離材
US8586360B2 (en) 2009-07-02 2013-11-19 Anthrogenesis Corporation Method of producing erythrocytes without feeder cells
DE102009052671B4 (de) 2009-11-12 2015-07-30 Sartorius Stedim Biotech Gmbh Vorrichtung und Verfahren zur Behandlung eines Filtrationsmediums
DK3284818T3 (da) 2010-01-26 2022-06-20 Celularity Inc Behandling af knoglerelateret kræft ved hjælp af placenta stamceller
EP2554190B1 (de) * 2010-03-31 2016-02-24 Asahi Kasei Medical Co., Ltd. System und verfahren zur entlüftung eines leukozytenentfernungsmittels
LT2556145T (lt) 2010-04-07 2016-11-10 Anthrogenesis Corporation Angiogenezė naudojant placentos kamienines ląsteles
MX2012011543A (es) 2010-04-08 2013-05-06 Anthrogenesis Corp Tratamiento de sarcoidosis empleando celulas madre placentarias.
ES2666746T3 (es) 2010-07-13 2018-05-07 Anthrogenesis Corporation Métodos para generar linfocitos citolíticos naturales
DE102010047826A1 (de) * 2010-10-04 2012-04-05 Eppendorf Ag Elektronische Pipette
JP2012120458A (ja) * 2010-12-06 2012-06-28 Kaneka Corp 細胞の分離器具。
JP2012120457A (ja) * 2010-12-06 2012-06-28 Kaneka Corp プライミング装置機能付き細胞分離装置およびそれを用いたプライミング法。
JP5738582B2 (ja) * 2010-12-06 2015-06-24 株式会社カネカ プライミング時の気泡の除去を簡便にする部材を備えた細胞溶液処理器具およびその使用方法
US8969315B2 (en) 2010-12-31 2015-03-03 Anthrogenesis Corporation Enhancement of placental stem cell potency using modulatory RNA molecules
EP2683470B1 (de) * 2011-03-11 2017-05-03 Fenwal, Inc. Membrantrennungsvorrichtungen, -systeme und -verfahren sowie datenverwaltungssysteme und -verfahren
JP6104896B2 (ja) 2011-06-01 2017-03-29 アントフロゲネシス コーポレーション 胎盤幹細胞を使用する疼痛の治療
JP2013034436A (ja) * 2011-08-09 2013-02-21 Kaneka Corp 細胞懸濁液の濃縮方法
DE102011112291B4 (de) * 2011-09-05 2015-07-09 Sartorius Stedim Biotech Gmbh Vorrichtung und Verfahren zur Filtration einer Flüssigkeitsprobe
WO2013055476A1 (en) 2011-09-09 2013-04-18 Anthrogenesis Corporation Treatment of amyotrophic lateral sclerosis using placental stem cells
WO2013102165A2 (en) * 2011-12-29 2013-07-04 Delcath Systems, Inc. Adjustable filter apparatus
IN2014DN09456A (de) * 2012-05-30 2015-07-17 Ge Healthcare Bio Sciences Ab
US10253295B2 (en) 2012-09-06 2019-04-09 Biomet Manufacturing, Llc Methods for producing rejuvenated red blood cells
US9066909B2 (en) 2012-09-06 2015-06-30 Biomet Biologics, Llc Methods for producing and using rejuvenated red blood cells
JP6113988B2 (ja) * 2012-09-26 2017-04-12 旭化成株式会社 腹水処理システム及び複合システム
US9103842B2 (en) 2013-01-31 2015-08-11 Biomet Biologics, Llc Methods for rejuvenating red blood cells
US9011408B2 (en) 2013-01-31 2015-04-21 Biomet Biologics, Llc Functionally-closed, sterile blood processing solution system and method
US9102918B2 (en) 2013-01-31 2015-08-11 Biomet Biologics, Llc Methods for rejuvenating red blood cells
CN115137753A (zh) 2013-02-05 2022-10-04 细胞结构公司 来自胎盘的自然杀伤细胞
JP6251998B2 (ja) * 2013-07-05 2017-12-27 日立化成株式会社 細胞捕捉システム及び細胞捕捉システムの運転方法
JP6299115B2 (ja) * 2013-08-29 2018-03-28 日立化成株式会社 細胞捕捉デバイス及び細胞捕捉システム
WO2015037468A1 (ja) * 2013-09-12 2015-03-19 ユニバーサル・バイオ・リサーチ株式会社 培養システム、及び培養方法
JPWO2015037120A1 (ja) * 2013-09-13 2017-03-02 株式会社メディネット 細胞懸濁液ろ過器具及び細胞懸濁液を含む点滴用溶液の調製方法
US9067172B1 (en) * 2014-01-28 2015-06-30 Air Products And Chemicals, Inc. Solid-state membrane module
US20150209721A1 (en) * 2014-01-28 2015-07-30 Air Products And Chemicals, Inc. Solid-State Membrane Module
EP3205712A4 (de) * 2014-10-08 2018-05-09 Hitachi Chemical Co., Ltd. Zellenerfassungsvorrichtung
KR101776245B1 (ko) 2014-11-20 2017-09-11 울산과학기술원 입자 여과 장치 및 입자 여과 방법
JP6615577B2 (ja) * 2015-10-29 2019-12-04 株式会社カネカ 細胞分離フィルターを用いた細胞濃縮液の製造方法
EP3471793B1 (de) * 2016-06-16 2023-12-20 Haemonetics Corporation Blutverarbeitungssystem mit einem y-verbinder
DE102018004521A1 (de) 2018-06-07 2019-12-12 Sartorius Stedim Biotech Gmbh Serielle Anordnung mit mehreren Lagen asymmetrischer Filtermedien, Herstellungsverfahren, Filtrationseinheit, Verwendung der Anordnung und Charakterisierungsverfahren
US11320345B2 (en) * 2019-03-18 2022-05-03 Avantor Fluid Handling, Llc Adjustable volume sampling system (AVSS)
CN110511860B (zh) * 2019-09-06 2022-09-06 辽宁鼎天生命科技有限公司 一种用于实验室提取干细胞的一体化装置
DE102019215029A1 (de) * 2019-09-30 2021-04-01 Robert Bosch Gmbh Filterabfolge, Spritzenaufsatz und Verfahren zur Separierung von Partikeln aus einer Körperflüssigkeit
DE102020216578B4 (de) * 2020-12-28 2023-02-09 Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung eingetragener Verein Vorrichtung und Verfahren zur Separation von unterschiedlich großen Partikeln in einer Flüssigkeit und Verwendungen der Vorrichtung
CN119142675B (zh) * 2024-11-18 2025-02-07 山东中瑞源生物科技有限公司 一种自体脂肪干细胞预处理设备

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1329559C (en) * 1988-03-03 1994-05-17 Keiji Naoi Leukocyte separator and method of making the same
JP3322595B2 (ja) * 1996-03-28 2002-09-09 テルモ株式会社 フィルター装置および生体微細組織の分離・回収方法
US6120474A (en) * 1997-12-15 2000-09-19 Nissho Corporation Blood component-recovering apparatus and a method for recovering blood components using the same

Also Published As

Publication number Publication date
US6312950B1 (en) 2001-11-06
EP0987034A3 (de) 2000-10-04
EP0987034B1 (de) 2006-08-23
JP2000083649A (ja) 2000-03-28
JP3517359B2 (ja) 2004-04-12
DE69932901T2 (de) 2007-03-01
EP0987034A2 (de) 2000-03-22
DE69932901D1 (de) 2006-10-05

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