MX342995B - Métodos de generar células asesinas naturales. - Google Patents

Métodos de generar células asesinas naturales.

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Publication number
MX342995B
MX342995B MX2013000395A MX2013000395A MX342995B MX 342995 B MX342995 B MX 342995B MX 2013000395 A MX2013000395 A MX 2013000395A MX 2013000395 A MX2013000395 A MX 2013000395A MX 342995 B MX342995 B MX 342995B
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MX
Mexico
Prior art keywords
methods
cells
murder
generating natural
cancer
Prior art date
Application number
MX2013000395A
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English (en)
Other versions
MX2013000395A (es
Inventor
J Hariri Robert
Zeitlin Andrew
A Heidaran Mohammad
Zhang Xiaokui
Pal Ajai
Law Eric
Voskinarian-Berse Vanessa
Kang Lin
Jasko Stephen
Stout Bhavani
Original Assignee
Anthrogenesis Corp
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Publication date
Application filed by Anthrogenesis Corp filed Critical Anthrogenesis Corp
Publication of MX2013000395A publication Critical patent/MX2013000395A/es
Publication of MX342995B publication Critical patent/MX342995B/es

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    • C12N5/06Animal cells or tissues; Human cells or tissues
    • C12N5/0602Vertebrate cells
    • C12N5/0634Cells from the blood or the immune system
    • C12N5/0646Natural killers cells [NK], NKT cells
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    • A61K35/12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/14Blood; Artificial blood
    • A61K35/17Lymphocytes; B-cells; T-cells; Natural killer cells; Interferon-activated or cytokine-activated lymphocytes
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    • A61K40/00Cellular immunotherapy
    • A61K40/10Cellular immunotherapy characterised by the cell type used
    • A61K40/15Natural-killer [NK] cells; Natural-killer T [NKT] cells
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    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • A61K40/42Cancer antigens
    • A61K40/428Undefined tumor antigens, e.g. tumor lysate or antigens targeted by cells isolated from tumor
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    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
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Abstract

La presente invención se refiere a métodos de producir células asesinas naturales usando un método de expansión y diferenciación de dos pasos. En la presente también se proveen métodos de suprimir la proliferación celular de tumor, de tratar individuos que tienen cáncer o una infección viral, que comprenden administrar las células NK producidas por el método a un individuo que tiene cáncer o infección viral.
MX2013000395A 2010-07-13 2011-07-13 Métodos de generar células asesinas naturales. MX342995B (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US36398110P 2010-07-13 2010-07-13
US201161497897P 2011-06-16 2011-06-16
PCT/US2011/043831 WO2012009422A1 (en) 2010-07-13 2011-07-13 Methods of generating natural killer cells

Publications (2)

Publication Number Publication Date
MX2013000395A MX2013000395A (es) 2013-03-22
MX342995B true MX342995B (es) 2016-10-21

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ID=44546146

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2013000395A MX342995B (es) 2010-07-13 2011-07-13 Métodos de generar células asesinas naturales.

Country Status (13)

Country Link
US (5) US8926964B2 (es)
EP (2) EP3358007A1 (es)
JP (5) JP5996533B2 (es)
KR (7) KR20220053695A (es)
CN (3) CN107828727A (es)
AU (1) AU2011279201B2 (es)
BR (1) BR112013000822B1 (es)
CA (1) CA2804750C (es)
ES (1) ES2666746T3 (es)
IL (2) IL224204B (es)
MX (1) MX342995B (es)
NZ (2) NZ605505A (es)
WO (1) WO2012009422A1 (es)

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US7498171B2 (en) 2002-04-12 2009-03-03 Anthrogenesis Corporation Modulation of stem and progenitor cell differentiation, assays, and uses thereof
ES2671355T3 (es) 2005-12-29 2018-06-06 Anthrogenesis Corporation Poblaciones de células madre placentarias
ZA200902233B (en) 2006-10-23 2010-07-28 Anthrogenesis Corp Methods and compositions for treatment of bone defects with placental cell populations
EP2129775A1 (en) * 2007-02-12 2009-12-09 Anthrogenesis Corporation Hepatocytes and chondrocytes from adherent placental stem cells; and cd34+, cd45- placental stem cell-enriched cell populations
US9200253B1 (en) 2007-08-06 2015-12-01 Anthrogenesis Corporation Method of producing erythrocytes
RS53841B1 (sr) 2007-09-28 2015-06-30 Anthrogenesis Corporation Supresija tumora korišćenjem humanog placentalnog perfuzata i intermedijernih ćelija ubica poreklom iz humane placente
DK2330889T3 (en) 2008-08-20 2017-01-30 Anthrogenesis Corp Improved cell composition and process for making the same
MX2011001992A (es) 2008-08-22 2011-03-29 Anthrogenesis Corp Metodos y composiciones para el tratamiento de defectos oseos con poblaciones de celulas placentarias.
AR077369A1 (es) 2009-07-02 2011-08-24 Anthrogenesis Corp Metodopara producir eritrocitos sin celulas alimentadoras
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AU2011237743A1 (en) 2010-04-08 2012-11-01 Anthrogenesis Corporation Treatment of sarcoidosis using placental stem cells
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AR093183A1 (es) 2010-12-31 2015-05-27 Anthrogenesis Corp Aumento de la potencia de celulas madre de placenta usando moleculas de arn moduladoras
EP3443968A1 (en) 2011-06-01 2019-02-20 Celularity, Inc. Treatment of pain using placental stem cells
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CN103372029A (zh) * 2012-04-19 2013-10-30 孙勇 肿瘤治疗用nk细胞新技术
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CN102994449A (zh) * 2012-12-13 2013-03-27 上海柯莱逊生物技术有限公司 一种体外扩增nk细胞的方法
AU2013204922B2 (en) 2012-12-20 2015-05-14 Celgene Corporation Chimeric antigen receptors
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JP5511039B1 (ja) * 2013-05-22 2014-06-04 国立大学法人九州大学 Nk細胞の調製方法
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CN106164256B (zh) * 2014-03-07 2021-08-10 艾美尔塞勒公司 来自脐带血的汇集的nk细胞和在治疗癌和慢性感染病中的应用
KR20210014210A (ko) 2014-05-15 2021-02-08 내셔널 유니버시티 오브 싱가포르 변형된 천연 살해 세포 및 그의 용도
CN105219710B (zh) * 2014-06-05 2020-01-10 上海厚超生物科技有限公司 一种高杀伤活性的免疫细胞群的培养方法
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CN103097520B (zh) 2017-12-05
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KR20130093091A (ko) 2013-08-21
US8926964B2 (en) 2015-01-06
KR20180099915A (ko) 2018-09-05
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